ATE278412T1 - Cyclosporin enthaltende weichkapselpräparate - Google Patents

Cyclosporin enthaltende weichkapselpräparate

Info

Publication number: ATE278412T1
Authority: AT; Austria
Prior art keywords: soft capsule; preparations containing; fatty acid; composition; capsule preparations
Prior art date: 1996-06-19

Application number

AT97929227T

Other languages

English (en)

Inventor

Jong Soo Woo

Original Assignee

Novartis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-19

Filing date

1997-06-19

Publication date

2004-10-15

1996-06-19 Priority claimed from KR1019960022417A external-priority patent/KR0183449B1/ko

1997-03-14 Priority claimed from KR1019970008750A external-priority patent/KR19980073479A/ko

1997-06-19 Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh

2004-10-15 Application granted granted Critical

2004-10-15 Publication of ATE278412T1 publication Critical patent/ATE278412T1/de

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
108010036949 Cyclosporine Proteins 0.000 title abstract 2
229960001265 ciclosporin Drugs 0.000 title abstract 2
229930182912 cyclosporin Natural products 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
239000007901 soft capsule Substances 0.000 title abstract 2
239000002202 Polyethylene glycol Substances 0.000 abstract 3
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
229920001223 polyethylene glycol Polymers 0.000 abstract 3
235000014113 dietary fatty acids Nutrition 0.000 abstract 2
239000000194 fatty acid Substances 0.000 abstract 2
229930195729 fatty acid Natural products 0.000 abstract 2
150000004665 fatty acids Chemical class 0.000 abstract 2
RUOJZAUFBMNUDX-UHFFFAOYSA-N propylene carbonate Chemical compound CC1COC(=O)O1 RUOJZAUFBMNUDX-UHFFFAOYSA-N 0.000 abstract 2
LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 abstract 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010010803 Gelatin Proteins 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000012141 concentrate Substances 0.000 abstract 1
238000001816 cooling Methods 0.000 abstract 1
229920000159 gelatin Polymers 0.000 abstract 1
239000008273 gelatin Substances 0.000 abstract 1
235000019322 gelatine Nutrition 0.000 abstract 1
235000011852 gelatine desserts Nutrition 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
239000004014 plasticizer Substances 0.000 abstract 1
150000003138 primary alcohols Chemical class 0.000 abstract 1
238000003756 stirring Methods 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Epidemiology (AREA)
Tropical Medicine & Parasitology (AREA)
Rheumatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Transplantation (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Cardiology (AREA)
Hematology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

AT97929227T 1996-06-19 1997-06-19 Cyclosporin enthaltende weichkapselpräparate ATE278412T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
KR1019960022417A KR0183449B1 (ko)	1996-06-19	1996-06-19	사이클로스포린-함유 연질캅셀제
KR1019970008750A KR19980073479A (ko)	1997-03-14	1997-03-14	사이클로스포린-함유 연질캅셀제
PCT/EP1997/003213 WO1997048410A1 (en)	1996-06-19	1997-06-19	Cyclosporin-containing soft capsule preparations

Publications (1)

Publication Number	Publication Date
ATE278412T1 true ATE278412T1 (de)	2004-10-15

Family

ID=26631929

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT03029109T ATE392891T1 (de)	1996-06-19	1997-06-19	Cyclosporin enthaltende präparate
AT97929227T ATE278412T1 (de)	1996-06-19	1997-06-19	Cyclosporin enthaltende weichkapselpräparate

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT03029109T ATE392891T1 (de)	1996-06-19	1997-06-19	Cyclosporin enthaltende präparate

Country Status (27)

Country	Link
EP (2)	EP1413297B1 (de)
JP (2)	JP3519414B2 (de)
KR (2)	KR20000016761A (de)
CN (2)	CN1127350C (de)
AT (2)	ATE392891T1 (de)
AU (1)	AU719251B2 (de)
BR (2)	BR9713811A (de)
CA (2)	CA2226091C (de)
CY (1)	CY2549B1 (de)
CZ (2)	CZ291641B6 (de)
DE (2)	DE69731072T2 (de)
DK (1)	DK0869810T3 (de)
ES (2)	ES2305396T3 (de)
HU (1)	HUP9801109A3 (de)
IL (5)	IL123840A (de)
MX (2)	MX9804414A (de)
MY (1)	MY117765A (de)
NO (2)	NO321921B1 (de)
NZ (1)	NZ330062A (de)
PL (1)	PL188500B1 (de)
PT (2)	PT869810E (de)
RU (2)	RU2185187C2 (de)
SG (1)	SG88752A1 (de)
SI (2)	SI9720011A (de)
SK (2)	SK283216B6 (de)
TR (2)	TR199800525T2 (de)
WO (1)	WO1997048410A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0869810T3 (da) *	1996-06-19	2005-02-07	Novartis Ag	Cyclosporinholdige blöde kapselpræparater
AU722285B2 (en) *	1996-06-19	2000-07-27	Novartis Ag	Cyclosporin-containing soft capsule preparations
KR19980073479A (ko) *	1997-03-14	1998-11-05	한스루돌프하우스, 니콜케르커	사이클로스포린-함유 연질캅셀제
US6008191A (en) *	1997-09-08	1999-12-28	Panacea Biotec Limited	Pharmaceutical compositions containing cyclosporin
US6346511B1 (en)	1997-09-08	2002-02-12	Panacea Biotec Limited	Pharmaceutical composition comprising cyclosporin
US6187747B1 (en)	1997-09-08	2001-02-13	Panacea Biotech Limited	Pharmaceutical composition comprising cyclosporin
NZ329929A (en) *	1998-03-09	1999-10-28	Bernard Charles Sherman	Pharmaceutical emulsion preconcentrate containing cyclosporin in a solvent system containing glycerides, propylene or polyethylene glycol, a surfactant and a co-surfactant
DK1154759T3 (da)	1998-12-30	2008-12-08	Dexcel Ltd	Dispergerbart koncentrat til indgift af cyclosporin
MXPA02004900A (es)	2000-09-18	2003-10-24	Rpg Life Sciences Ltd	Formulacion autoemulsificable, con mejores actividades de bioabsorcion e inmunosupresion.
TNSN03139A1 (fr)	2001-06-21	2005-12-23	Pfizer Prod Inc	Formulations auto-emulsionnables d'inhibiteurs de la proteine de transfert d'ester de cholesteryle
ES2310604T3 (es) *	2001-10-19	2009-01-16	Isotechnika, Inc.	Mezclas de analogos de ciclosporinas y su uso como agentes inmunomoduladores.
EP2116228A1 (de)	2001-10-19	2009-11-11	Isotechnika Inc.	Neuartige Cyclosporinanalog-Mikroemulsionspräkonzentrate
KR100533460B1 (ko) *	2002-07-20	2005-12-08	대화제약 주식회사	난용성 약물의 가용화용 점막흡착성 조성물, 이를 이용한난용성 약물의 가용화용 제형 및 이들의 제조 방법
US20070092559A1 (en) *	2005-10-24	2007-04-26	Jinghua Yuan	Liquid dosage forms having enteric properties of delayed and then sustained release
FR3029792B1 (fr) *	2014-12-15	2018-01-26	Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic	Liberation maitrisee de substances actives.
KR20170001569U (ko)	2015-10-27	2017-05-10	이제홍	쑥뜸장치

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU633207B2 (en) *	1990-03-30	1993-01-21	Alza Corporation	Compositions comprising cytotoxic agent and permeation enhancers
GB9113872D0 (en) *	1991-06-27	1991-08-14	Sandoz Ag	Improvements in or relating to organic compounds
HU215966B (hu) *	1994-11-21	1999-07-28	BIOGAL Gyógyszergyár Rt.	Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
KR0167613B1 (ko) *	1994-12-28	1999-01-15	한스 루돌프 하우스, 니콜 케르커	사이클로스포린-함유 연질캅셀제 조성물
NZ280689A (en) *	1995-12-15	1997-08-22	Bernard Charles Sherma Sherman	Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol
DK0869810T3 (da) *	1996-06-19	2005-02-07	Novartis Ag	Cyclosporinholdige blöde kapselpræparater

1997
- 1997-06-19 DK DK97929227T patent/DK0869810T3/da active
- 1997-06-19 PT PT97929227T patent/PT869810E/pt unknown
- 1997-06-19 CZ CZ1998834A patent/CZ291641B6/cs not_active IP Right Cessation
- 1997-06-19 IL IL12384097A patent/IL123840A/en not_active IP Right Cessation
- 1997-06-19 CN CN97191060A patent/CN1127350C/zh not_active Expired - Fee Related
- 1997-06-19 SI SI9720011A patent/SI9720011A/sl not_active IP Right Cessation
- 1997-06-19 SK SK371-98A patent/SK283216B6/sk not_active IP Right Cessation
- 1997-06-19 AU AU33411/97A patent/AU719251B2/en not_active Ceased
- 1997-06-19 CA CA002226091A patent/CA2226091C/en not_active Expired - Fee Related
- 1997-06-19 DE DE69731072T patent/DE69731072T2/de not_active Expired - Fee Related
- 1997-06-19 KR KR1019980710368A patent/KR20000016761A/ko not_active Withdrawn
- 1997-06-19 DE DE69738656T patent/DE69738656T2/de not_active Expired - Fee Related
- 1997-06-19 PL PL97325832A patent/PL188500B1/pl not_active IP Right Cessation
- 1997-06-19 EP EP03029109A patent/EP1413297B1/de not_active Expired - Lifetime
- 1997-06-19 CA CA002240705A patent/CA2240705C/en not_active Expired - Fee Related
- 1997-06-19 BR BR9713811-8A patent/BR9713811A/pt not_active Application Discontinuation
- 1997-06-19 HU HU9801109A patent/HUP9801109A3/hu unknown
- 1997-06-19 PT PT03029109T patent/PT1413297E/pt unknown
- 1997-06-19 ES ES03029109T patent/ES2305396T3/es not_active Expired - Lifetime
- 1997-06-19 NZ NZ330062A patent/NZ330062A/xx unknown
- 1997-06-19 JP JP50229798A patent/JP3519414B2/ja not_active Expired - Fee Related
- 1997-06-19 SK SK372-98A patent/SK283361B6/sk not_active IP Right Cessation
- 1997-06-19 SI SI9720010A patent/SI9720010B/sl not_active IP Right Cessation
- 1997-06-19 MY MYPI97002776A patent/MY117765A/en unknown
- 1997-06-19 SG SG9901629A patent/SG88752A1/en unknown
- 1997-06-19 IL IL14736997A patent/IL147369A/en not_active IP Right Cessation
- 1997-06-19 AT AT03029109T patent/ATE392891T1/de not_active IP Right Cessation
- 1997-06-19 BR BR9706804-7A patent/BR9706804A/pt not_active IP Right Cessation
- 1997-06-19 WO PCT/EP1997/003213 patent/WO1997048410A1/en not_active Ceased
- 1997-06-19 TR TR1998/00525T patent/TR199800525T2/xx unknown
- 1997-06-19 IL IL12367697A patent/IL123676A/en not_active IP Right Cessation
- 1997-06-19 ES ES97929227T patent/ES2227700T3/es not_active Expired - Lifetime
- 1997-06-19 RU RU98106393/14A patent/RU2185187C2/ru not_active IP Right Cessation
- 1997-06-19 TR TR1998/00526T patent/TR199800526T2/xx unknown
- 1997-06-19 AT AT97929227T patent/ATE278412T1/de not_active IP Right Cessation
- 1997-06-19 CN CNA2003101142054A patent/CN1494920A/zh active Pending
- 1997-06-19 CZ CZ1998835A patent/CZ292378B6/cs not_active IP Right Cessation
- 1997-06-19 RU RU98105629/14A patent/RU2181055C2/ru not_active IP Right Cessation
- 1997-06-19 KR KR10-2003-7000108A patent/KR20040000379A/ko not_active Ceased
- 1997-06-19 EP EP97929227A patent/EP0869810B1/de not_active Expired - Lifetime
1998
- 1998-03-17 NO NO19981200A patent/NO321921B1/no not_active IP Right Cessation
- 1998-03-26 IL IL12384098A patent/IL123840A0/xx unknown
- 1998-05-26 NO NO19982382A patent/NO323816B1/no not_active IP Right Cessation
- 1998-06-03 MX MX9804414A patent/MX9804414A/es not_active IP Right Cessation
- 1998-06-04 MX MX9804442A patent/MX9804442A/es not_active IP Right Cessation
2001
- 2001-12-27 IL IL14736901A patent/IL147369A0/xx unknown
2003
- 2003-11-06 JP JP2003376460A patent/JP2004043511A/ja not_active Withdrawn
2006
- 2006-02-13 CY CY0600003A patent/CY2549B1/xx unknown

Also Published As

Publication number	Publication date
DE69731072T2 (de)	2005-10-06
IL123840A (en)	2002-07-25
EP1413297A1 (de)	2004-04-28
IL147369A (en)	2002-12-01
MX9804442A (es)	1998-09-30
SI9720010B (sl)	2009-10-31
RU2181055C2 (ru)	2002-04-10
CZ83598A3 (cs)	1998-07-15
CY2549B1 (en)	2008-07-02
EP1413297B1 (de)	2008-04-23
PT869810E (pt)	2005-01-31
CN1207044A (zh)	1999-02-03
PT1413297E (pt)	2008-07-28
CA2226091A1 (en)	1997-12-24
TR199800525T2 (xx)	1999-02-22
IL147369A0 (en)	2002-08-14
CZ83498A3 (cs)	1998-07-15
HUP9801109A3 (en)	2000-06-28
PL325832A1 (en)	1999-01-04
JP3519414B2 (ja)	2004-04-12
HUP9801109A2 (hu)	1999-08-30
IL123676A0 (en)	1998-10-30
CZ291641B6 (cs)	2003-04-16
NO321921B1 (no)	2006-07-24
WO1997048410A1 (en)	1997-12-24
SI9720011A (sl)	1998-10-31
PL188500B1 (pl)	2005-02-28
EP0869810A1 (de)	1998-10-14
NO981200L (no)	1998-03-17
NO982382L (no)	1998-05-26
SK37198A3 (en)	1998-10-07
CA2226091C (en)	1999-02-09
NZ330062A (en)	2000-01-28
NO323816B1 (no)	2007-07-09
NO982382D0 (no)	1998-05-26
BR9706804A (pt)	1999-11-03
ES2305396T3 (es)	2008-11-01
CN1494920A (zh)	2004-05-12
JP2004043511A (ja)	2004-02-12
EP0869810B1 (de)	2004-10-06
BR9713811A (pt)	2004-03-02
ATE392891T1 (de)	2008-05-15
IL123840A0 (en)	1998-10-30
CA2240705C (en)	2007-07-31
JP2000505480A (ja)	2000-05-09
IL123676A (en)	2002-02-10
DE69731072D1 (de)	2004-11-11
NO981200D0 (no)	1998-03-17
RU2185187C2 (ru)	2002-07-20
AU719251B2 (en)	2000-05-04
ES2227700T3 (es)	2005-04-01
AU3341197A (en)	1998-01-07
DE69738656T2 (de)	2009-06-04
CZ292378B6 (cs)	2003-09-17
KR20040000379A (ko)	2004-01-03
HK1010492A1 (en)	1999-06-25
SI9720010A (sl)	1998-10-31
SK37298A3 (en)	1998-10-07
CN1127350C (zh)	2003-11-12
DE69738656D1 (de)	2008-06-05
TR199800526T2 (xx)	1999-02-22
KR20000016761A (ko)	2000-03-25
MY117765A (en)	2004-08-30
DK0869810T3 (da)	2005-02-07
CA2240705A1 (en)	1997-12-24
SG88752A1 (en)	2002-05-21
SK283216B6 (sk)	2003-03-04
SK283361B6 (sk)	2003-06-03
MX9804414A (es)	1998-09-30

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2011-03-15

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Publication	Publication Date	Title
ATE392891T1 (de)	2008-05-15	Cyclosporin enthaltende präparate
ES2122980T3 (es)	1999-01-01	Composiciones farmaceuticas topicas antimicrobianas.
KR980000466A (ko)	1998-03-30	사이클로스포린-함유 연질캅셀제
FR2710535B1 (fr)	1995-11-24	Composition à usage pharmaceutique ou cosmétique apte à former une microémulsion.
ATE265847T1 (de)	2004-05-15	Selbstemulgierbare formulierung enthaltend lipophile verbindungen
AU692801B2 (en)	1998-06-18	Pharmaceutical compositions comprising a staurosporine as active ingredient.
RU98106393A (ru)	2000-09-20	Препараты, содержащие циклоспорин, в виде капсул с мягким покрытием
RU98105629A (ru)	2000-02-10	Препараты, содержащие циклоспорин, в виде капсул с мягким покрытием
ECSP972157A (es)	1998-09-22	Preparaciones de capsula suave que contienen ciclosporina
CO4940404A1 (es)	2000-07-24	Composiciones farmaceuticas
RU99121398A (ru)	2001-12-27	Фармацевтические композиции
TH31345A (th)	1998-12-15	สารเตรียมแคปซูลอ่อนที่ประกอบด้วยไซโคลสพอริน
TH21053B (th)	2006-12-14	สารเตรียมแคปซูลอ่อนที่ประกอบด้วยไซโคลสพอริน