ATE293455T1 - Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus - Google Patents

Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus

Info

Publication number
ATE293455T1
ATE293455T1 AT99924055T AT99924055T ATE293455T1 AT E293455 T1 ATE293455 T1 AT E293455T1 AT 99924055 T AT99924055 T AT 99924055T AT 99924055 T AT99924055 T AT 99924055T AT E293455 T1 ATE293455 T1 AT E293455T1
Authority
AT
Austria
Prior art keywords
preventing
pruritus
tuber
treating inflammation
root derived
Prior art date
Application number
AT99924055T
Other languages
English (en)
Inventor
Embden Johanna Gee Ruseler-Van
Lieshout Leonarda Maria Ca Van
Jon Daniel Laman
Original Assignee
Univ Erasmus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Erasmus filed Critical Univ Erasmus
Application granted granted Critical
Publication of ATE293455T1 publication Critical patent/ATE293455T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/56—Protease inhibitors from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A61L2300/434—Inhibitors, antagonists of enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Materials Engineering (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
AT99924055T 1998-05-20 1999-05-20 Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus ATE293455T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98201694A EP0958833A1 (de) 1998-05-20 1998-05-20 Verfahren und Mittel zur Vorbeugung oder Behandlung der Entzündung
PCT/NL1999/000312 WO1999059623A1 (en) 1998-05-20 1999-05-20 Methods and means for preventing or treating inflammation or pruritis

Publications (1)

Publication Number Publication Date
ATE293455T1 true ATE293455T1 (de) 2005-05-15

Family

ID=8233748

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99924055T ATE293455T1 (de) 1998-05-20 1999-05-20 Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus

Country Status (11)

Country Link
US (1) US6723354B1 (de)
EP (2) EP0958833A1 (de)
JP (1) JP4633926B2 (de)
AT (1) ATE293455T1 (de)
AU (1) AU768615B2 (de)
CA (1) CA2332370C (de)
DE (1) DE69924842T2 (de)
DK (1) DK1079853T3 (de)
ES (1) ES2245510T3 (de)
NZ (1) NZ508406A (de)
WO (1) WO1999059623A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6703536B2 (en) 1998-03-12 2004-03-09 The Procter & Gamble Company Disposable absorbent article having a skin care composition containing an enzyme inhibitor
ATE239512T1 (de) 1998-03-12 2003-05-15 Procter & Gamble Protease-inhibitoren für absorbierende artikel
US6207596B1 (en) 1998-11-09 2001-03-27 The Procter & Gamble Company Disposable premoistened wipe containing an antimicrobial protease inhibitor
ITMI20020756A1 (it) * 2002-04-09 2003-10-09 Sinclair Pharma S R L Composizioni farmaceutiche topiche per il trattamento delle dermatiti
FR2865133B1 (fr) * 2004-01-19 2008-01-18 Rytek Compositions pour le traitement de pathologies digestives
US7858836B2 (en) * 2004-12-27 2010-12-28 Convatec Technologies Inc. Enzyme inhibiting adhesives
NZ547991A (en) * 2005-06-22 2008-08-29 Bristol Myers Squibb Co Enzyme inhibiting sprayable skin barrier compositions comprising enzyme inhibitors derived from potatoes
RU2443424C2 (ru) 2005-12-06 2012-02-27 Осира Терапьютикс, Инкорпорэйтд (Сша/Сша) Применение микросферического углеродного адсорбента для лечения синдрома раздраженной толстой кишки
WO2008069649A1 (en) * 2006-11-10 2008-06-12 Coöperatie Avebe U.A. Protein gel formation
EP1920662A1 (de) 2006-11-10 2008-05-14 Coöperatie Avebe U.A. Natives Kartoffelproteinisolat
US20080213252A1 (en) * 2007-01-03 2008-09-04 Ethan Lerner Methods of treating itch
WO2008092450A1 (en) * 2007-01-29 2008-08-07 Upfront Chromatography A/S Isolation and separation of minimally denatured potato proteins and peptides
KR101530398B1 (ko) * 2007-09-20 2015-06-19 카오카부시키가이샤 β-글루쿠로니다아제 저해제
US20090148538A1 (en) * 2007-10-12 2009-06-11 Ocera Therapeutics, Inc. Use of adsorbent carbon microspheres to treat pouchitis
US8563799B2 (en) 2008-02-25 2013-10-22 Teikoku Seiyaku Co., Ltd. Wound-covering hydrogel material
US8852569B2 (en) * 2008-08-28 2014-10-07 The General Hospital Corporation Prevention and treatment of itch with cysteine protease inhibition
US8817379B2 (en) 2011-07-12 2014-08-26 Google Inc. Whole image scanning mirror display system
US8471967B2 (en) 2011-07-15 2013-06-25 Google Inc. Eyepiece for near-to-eye display with multi-reflectors
US8670000B2 (en) 2011-09-12 2014-03-11 Google Inc. Optical display system and method with virtual image contrast control
US8786686B1 (en) 2011-09-16 2014-07-22 Google Inc. Head mounted display eyepiece with integrated depth sensing
PL406918A1 (pl) 2014-01-24 2015-08-03 Uniwersytet Przyrodniczy W Poznaniu Sposób otrzymywania preparatu z soku ziemniaka oraz jego zastosowanie
US10426815B2 (en) 2015-01-20 2019-10-01 The General Hospital Corporation Prevention and treatment of itch with an MRGPR antagonist
CN107683144B (zh) * 2015-04-17 2020-08-07 欧洲药物实验室公司 在预防和/或治疗皮肤损伤中使用的至少一种蛋白酶抑制剂和至少一种活性成分的组合
CN107303395B (zh) * 2016-04-19 2021-07-30 北京泰德制药股份有限公司 一种含有链霉蛋白酶的药物组合物及其制备方法
JP2022539535A (ja) * 2019-07-03 2022-09-12 コロプラスト アクティーゼルスカブ スキンケア用組成物
EP4051379A4 (de) * 2019-10-29 2023-12-13 The Regents of the University of California Therapeutisches verfahren zur behandlung einer entzündlichen darmerkrankung

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754278A (fr) * 1969-08-02 1971-02-01 Bayer Ag Procede d'utilisation d'inhibiteurs biologiques de proteases comme desodorisants
JPH0694420B2 (ja) * 1983-03-31 1994-11-24 恒 美原 血栓溶解剤
JPS61126031A (ja) * 1984-11-26 1986-06-13 Agency Of Ind Science & Technol コロニ−形成刺激因子の製造法
US4906457A (en) * 1988-09-06 1990-03-06 Washington State University Research Foundation, Inc. Compositions and methods for reducing the risk of sunlight and ultraviolet induced skin cancer
DK0462207T3 (da) * 1989-03-06 2001-06-18 Univ Texas t-Pa mutanter resistente mod deres respektive inhibitorer
FR2651125B1 (fr) * 1989-08-23 1992-10-02 Roussel Uclaf Compositions pharmaceutiques de type "pates a l'eau".
JPH0398596A (ja) * 1989-09-11 1991-04-24 Chisso Corp モノクローナル抗体
JP2938507B2 (ja) * 1990-03-20 1999-08-23 株式会社日本触媒 紙おむつ
DE4107765A1 (de) * 1990-07-28 1992-01-30 Schebo Tech Medizinisch Biolog Pankreas-elastase-1-spezifischer antikoerper, ein verfahren zu seiner gewinnung und ein testkit der solche antikoerper enthaelt
JPH04178335A (ja) * 1990-11-09 1992-06-25 Taiyo Kagaku Co Ltd ウイルス性下痢症治療剤
JPH04182423A (ja) * 1990-11-16 1992-06-30 Shiseido Co Ltd 清浄・清拭剤組成物
JP3159509B2 (ja) * 1992-03-30 2001-04-23 サンスター株式会社 プロテアーゼ阻害剤
IL101492A0 (en) * 1992-04-03 1992-12-30 Shalom Levy Anti-skin rash preparation
JPH06192085A (ja) * 1992-08-31 1994-07-12 Yuji Inada ダニアレルギー治療剤
NZ258824A (en) * 1992-12-16 1997-11-24 Univ Melbourne Nucleic acid encoding type ii serine proteinase inhibitor precursor and its use
WO1995012408A1 (en) * 1993-11-04 1995-05-11 Brigham & Women's Hospital Plasmin-independent fibrinolysis
JP3432260B2 (ja) * 1993-11-07 2003-08-04 日本水産株式会社 魚肉水溶性タンパク質の分画濃縮物を主要成分とする食品物性改良剤
US5614198A (en) * 1995-07-25 1997-03-25 The Trustees Of The University Of Pennsylvania Bowman-Birk Inhibitor compositions for treatment of inflammatory disease
JP3945544B2 (ja) * 1995-12-27 2007-07-18 ピジョン株式会社 ダイズエキスの製造方法
GB2311727A (en) * 1996-03-28 1997-10-08 Hanson Shaw Beverley Jane Sanitary article with treatment substance

Also Published As

Publication number Publication date
CA2332370C (en) 2012-01-24
AU4064299A (en) 1999-12-06
AU768615B2 (en) 2003-12-18
EP0958833A1 (de) 1999-11-24
ES2245510T3 (es) 2006-01-01
CA2332370A1 (en) 1999-11-25
DK1079853T3 (da) 2005-08-29
NZ508406A (en) 2003-08-29
DE69924842T2 (de) 2006-02-16
JP4633926B2 (ja) 2011-02-16
JP2002515454A (ja) 2002-05-28
EP1079853B1 (de) 2005-04-20
US6723354B1 (en) 2004-04-20
WO1999059623A1 (en) 1999-11-25
DE69924842D1 (de) 2005-05-25
EP1079853A1 (de) 2001-03-07

Similar Documents

Publication Publication Date Title
DE69924842D1 (de) Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus
BR9607474A (pt) Processos para liquefazer composições de amido e para desativar uma enzima hidrolisadora e composição de matéria
ATE241358T1 (de) Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen
ATE244511T1 (de) Verfahren zur behandlung von getreidekernen
DE69840126D1 (de) Verfahren zur prophylaxis oder behandlung von östrogen-abhängigen krankheiten
DE60140385D1 (de) Pektinase-Behandlung von Kartoffelprodukten
DE60142839D1 (de) Botulinum Toxin zur Behandlung von akuten Verletzungen der Skelettmuskeln
DE69629578D1 (de) Verwendung von wenigstens einem no-synthase hemmer zur behandlung empfindlicher haut
DE69911919D1 (de) Verfahren zur behandlung von obst und gemüse nach der ernte mit eugenol und/oder isoeugenol
DE69019072D1 (de) Zusammensetzungen und methode zur behandlung oder prophylaxe von sepsis oder septischem schock.
DE69939481D1 (de) Methode zur behandlung von diabetes die einen ap2-inhibitor und dazugehörige kombinationen verwendet
DE60229406D1 (de) Verfahren zur behandlung oder verhinderung von vaskulärer entzündung mit sterol-absorbierungs- inhibitor(en)
DE602004003587D1 (de) Kosmetische verwendung einer zusammensetzung mit mindestens einem oxazolin als wirkstoff, als abnehmprodukt und/oder zur prävention und/oder behandlung von cellulite
ATE258796T1 (de) Verwendung von vitamin d4-derivaten zur behandlung von hauterkrankungen
ATE555803T1 (de) Verwendung von osteopontin zur behandlung und/oder vorbeugung von neurologischen erkrankungen
DE69228188D1 (de) Verfahren zur behandlung von pflanzen oder pflanzlichem gewebe
ATE415822T1 (de) Verfahren zur behandlung von avocado und verfahren zur herstellung von guacamole
ATE239468T1 (de) Verwendung von carbonanhydrase-hemmern zur behandlung von makulär-ödemen
FR2810507B1 (fr) Procede de traitement de tubercules ou racines et plus generalement de legumes et de fruits destines a etre coupes, notamment avant cuisson
BR9902736A (pt) Processo de tratamento de frutas e legumes
ATE239467T1 (de) Methode zur behandlung oder verhütung von interstitieller blasenentzundung
ATE187205T1 (de) Verfahren zur lederherstellung beinhaltend eine enzymatische behandlung der hautblösse mit einer trypsinaktiven mikrobiellen protease
ATE338566T1 (de) Aldosteronantagonist und cyclooxygenase-2 hemmer- kombinationstherapie zur verhinderung oder behandlung von entzündungsverwandten kardiovaskulären krankheiten
PT1130978E (pt) Metodo para cobrir um produto alimentar com colagenio
DE69617599D1 (de) Verfahren zur Behandlung von gefrorenen Blattgemüse-Portionen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1079853

Country of ref document: EP