ATE293455T1 - Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus - Google Patents

Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus

Info

Publication number
ATE293455T1
ATE293455T1 AT99924055T AT99924055T ATE293455T1 AT E293455 T1 ATE293455 T1 AT E293455T1 AT 99924055 T AT99924055 T AT 99924055T AT 99924055 T AT99924055 T AT 99924055T AT E293455 T1 ATE293455 T1 AT E293455T1
Authority
AT
Austria
Prior art keywords
preventing
pruritus
tuber
treating inflammation
root derived
Prior art date
Application number
AT99924055T
Other languages
English (en)
Inventor
Embden Johanna Gee Ruseler-Van
Lieshout Leonarda Maria Ca Van
Jon Daniel Laman
Original Assignee
Univ Erasmus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Erasmus filed Critical Univ Erasmus
Application granted granted Critical
Publication of ATE293455T1 publication Critical patent/ATE293455T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/56—Protease inhibitors from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A61L2300/434—Inhibitors, antagonists of enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
AT99924055T 1998-05-20 1999-05-20 Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus ATE293455T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98201694A EP0958833A1 (de) 1998-05-20 1998-05-20 Verfahren und Mittel zur Vorbeugung oder Behandlung der Entzündung
PCT/NL1999/000312 WO1999059623A1 (en) 1998-05-20 1999-05-20 Methods and means for preventing or treating inflammation or pruritis

Publications (1)

Publication Number Publication Date
ATE293455T1 true ATE293455T1 (de) 2005-05-15

Family

ID=8233748

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99924055T ATE293455T1 (de) 1998-05-20 1999-05-20 Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus

Country Status (11)

Country Link
US (1) US6723354B1 (de)
EP (2) EP0958833A1 (de)
JP (1) JP4633926B2 (de)
AT (1) ATE293455T1 (de)
AU (1) AU768615B2 (de)
CA (1) CA2332370C (de)
DE (1) DE69924842T2 (de)
DK (1) DK1079853T3 (de)
ES (1) ES2245510T3 (de)
NZ (1) NZ508406A (de)
WO (1) WO1999059623A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE239512T1 (de) 1998-03-12 2003-05-15 Procter & Gamble Protease-inhibitoren für absorbierende artikel
US6703536B2 (en) 1998-03-12 2004-03-09 The Procter & Gamble Company Disposable absorbent article having a skin care composition containing an enzyme inhibitor
US6207596B1 (en) 1998-11-09 2001-03-27 The Procter & Gamble Company Disposable premoistened wipe containing an antimicrobial protease inhibitor
ITMI20020756A1 (it) * 2002-04-09 2003-10-09 Sinclair Pharma S R L Composizioni farmaceutiche topiche per il trattamento delle dermatiti
FR2865133B1 (fr) * 2004-01-19 2008-01-18 Rytek Compositions pour le traitement de pathologies digestives
US7858836B2 (en) * 2004-12-27 2010-12-28 Convatec Technologies Inc. Enzyme inhibiting adhesives
NZ547991A (en) * 2005-06-22 2008-08-29 Bristol Myers Squibb Co Enzyme inhibiting sprayable skin barrier compositions comprising enzyme inhibitors derived from potatoes
US7749497B2 (en) 2005-12-06 2010-07-06 Ocera Therapeutics, Inc. Use of adsorbent carbon microspheres for the treatment of irritable bowel syndrome
EP1920662A1 (de) 2006-11-10 2008-05-14 Coöperatie Avebe U.A. Natives Kartoffelproteinisolat
WO2008069649A1 (en) * 2006-11-10 2008-06-12 Coöperatie Avebe U.A. Protein gel formation
WO2008086069A1 (en) * 2007-01-03 2008-07-17 The General Hospital Corporation Methods of treating itch
WO2008092450A1 (en) * 2007-01-29 2008-08-07 Upfront Chromatography A/S Isolation and separation of minimally denatured potato proteins and peptides
WO2009037861A1 (ja) * 2007-09-20 2009-03-26 Kao Corporation β-グルクロニダーゼ阻害剤
WO2009049239A1 (en) * 2007-10-12 2009-04-16 Ocera Therapeutics, Inc. Use of adsorbent carbon microspheres to treat pouchitis
BRPI0822305B8 (pt) 2008-02-25 2021-06-22 Teikoku Seiyaku Kk material de hidrogel protetor de feridas
US8852569B2 (en) * 2008-08-28 2014-10-07 The General Hospital Corporation Prevention and treatment of itch with cysteine protease inhibition
US8817379B2 (en) 2011-07-12 2014-08-26 Google Inc. Whole image scanning mirror display system
US8471967B2 (en) 2011-07-15 2013-06-25 Google Inc. Eyepiece for near-to-eye display with multi-reflectors
US8670000B2 (en) 2011-09-12 2014-03-11 Google Inc. Optical display system and method with virtual image contrast control
US8786686B1 (en) 2011-09-16 2014-07-22 Google Inc. Head mounted display eyepiece with integrated depth sensing
PL406918A1 (pl) 2014-01-24 2015-08-03 Uniwersytet Przyrodniczy W Poznaniu Sposób otrzymywania preparatu z soku ziemniaka oraz jego zastosowanie
WO2016118632A1 (en) 2015-01-20 2016-07-28 The General Hospital Corporation Prevention and treatment of itch with an mrgpr antagonist
BR112017022286A2 (pt) * 2015-04-17 2018-07-10 Eurodrug Laboratories B V combinação, composição farmacêutica e uso da combinação
CN107303395B (zh) * 2016-04-19 2021-07-30 北京泰德制药股份有限公司 一种含有链霉蛋白酶的药物组合物及其制备方法
CN114007580B (zh) * 2019-07-03 2023-12-05 科洛普拉斯特公司 皮肤护理组合物
EP4051379A4 (de) * 2019-10-29 2023-12-13 The Regents of the University of California Therapeutisches verfahren zur behandlung einer entzündlichen darmerkrankung

Family Cites Families (20)

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BE754278A (fr) * 1969-08-02 1971-02-01 Bayer Ag Procede d'utilisation d'inhibiteurs biologiques de proteases comme desodorisants
JPH0694420B2 (ja) * 1983-03-31 1994-11-24 恒 美原 血栓溶解剤
JPS61126031A (ja) * 1984-11-26 1986-06-13 Agency Of Ind Science & Technol コロニ−形成刺激因子の製造法
US4906457A (en) * 1988-09-06 1990-03-06 Washington State University Research Foundation, Inc. Compositions and methods for reducing the risk of sunlight and ultraviolet induced skin cancer
EP0462207B1 (de) * 1989-03-06 2001-02-07 Board Of Regents, The University Of Texas System Gegenüber eigenen inhibitoren resistente t-pa mutanten
FR2651125B1 (fr) * 1989-08-23 1992-10-02 Roussel Uclaf Compositions pharmaceutiques de type "pates a l'eau".
JPH0398596A (ja) * 1989-09-11 1991-04-24 Chisso Corp モノクローナル抗体
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Also Published As

Publication number Publication date
DK1079853T3 (da) 2005-08-29
EP1079853B1 (de) 2005-04-20
CA2332370C (en) 2012-01-24
JP2002515454A (ja) 2002-05-28
DE69924842D1 (de) 2005-05-25
JP4633926B2 (ja) 2011-02-16
CA2332370A1 (en) 1999-11-25
EP1079853A1 (de) 2001-03-07
DE69924842T2 (de) 2006-02-16
ES2245510T3 (es) 2006-01-01
WO1999059623A1 (en) 1999-11-25
AU768615B2 (en) 2003-12-18
NZ508406A (en) 2003-08-29
EP0958833A1 (de) 1999-11-24
AU4064299A (en) 1999-12-06
US6723354B1 (en) 2004-04-20

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