ATE295852T1 - Antibiotische tripropeptine und verfahren ihrer herstellung - Google Patents

Antibiotische tripropeptine und verfahren ihrer herstellung

Info

Publication number: ATE295852T1
Authority: AT; Austria
Prior art keywords: tripropeptin; methyl; group; resistant strains; tripropeptins
Prior art date: 2000-03-30

Application number

AT01917554T

Other languages

English (en)

Inventor

Tomio Takeuchi

Hideki Hashizume

Masayuki Igarashi

Hiroshi Naganawa

Masa Hamada

Original Assignee

Zaidan Hojin Biseibutsu

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-30

Filing date

2001-03-28

Publication date

2005-06-15

2001-03-28 Application filed by Zaidan Hojin Biseibutsu filed Critical Zaidan Hojin Biseibutsu

2005-06-15 Application granted granted Critical

2005-06-15 Publication of ATE295852T1 publication Critical patent/ATE295852T1/de

Links

230000003115 biocidal effect Effects 0.000 title abstract 2
-1 7-methyl-octyl group Chemical group 0.000 abstract 5
241000894006 Bacteria Species 0.000 abstract 2
239000003242 anti bacterial agent Substances 0.000 abstract 2
230000000844 anti-bacterial effect Effects 0.000 abstract 2
241001248650 Lysobacter sp. Species 0.000 abstract 1
RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 abstract 1
108010059993 Vancomycin Proteins 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
238000012258 culturing Methods 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
229960003085 meticillin Drugs 0.000 abstract 1
108010091003 tripropeptin C Proteins 0.000 abstract 1
ZJFQULWBEYLWOH-UHFFFAOYSA-N tripropeptin a Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 ZJFQULWBEYLWOH-UHFFFAOYSA-N 0.000 abstract 1
HDRXFYLSJDHVBY-UHFFFAOYSA-N tripropeptin b Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 HDRXFYLSJDHVBY-UHFFFAOYSA-N 0.000 abstract 1
ZRHHHIZQDIARCA-UHFFFAOYSA-N tripropeptin c Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 ZRHHHIZQDIARCA-UHFFFAOYSA-N 0.000 abstract 1
DETFTHHTKCLOGR-UHFFFAOYSA-N tripropeptin d Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 DETFTHHTKCLOGR-UHFFFAOYSA-N 0.000 abstract 1
CDGPSUVNLUGBRV-UHFFFAOYSA-N tripropeptin z Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 CDGPSUVNLUGBRV-UHFFFAOYSA-N 0.000 abstract 1
229960003165 vancomycin Drugs 0.000 abstract 1
MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 abstract 1
MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oncology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Veterinary Medicine (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Compounds Of Unknown Constitution (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT01917554T 2000-03-30 2001-03-28 Antibiotische tripropeptine und verfahren ihrer herstellung ATE295852T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2000093405		2000-03-30
PCT/JP2001/002578 WO2001074850A1 (en)	2000-03-30	2001-03-28	Antibiotics tripropeptins and process for producing the same

Publications (1)

Publication Number	Publication Date
ATE295852T1 true ATE295852T1 (de)	2005-06-15

Family

ID=18608597

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01917554T ATE295852T1 (de)	2000-03-30	2001-03-28	Antibiotische tripropeptine und verfahren ihrer herstellung

Country Status (8)

Country	Link
US (1)	US7271147B2 (de)
EP (1)	EP1285928B1 (de)
JP (1)	JP4054576B2 (de)
AT (1)	ATE295852T1 (de)
AU (1)	AU2001244594A1 (de)
DE (1)	DE60110908T2 (de)
ES (1)	ES2240434T3 (de)
WO (1)	WO2001074850A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2011148959A1 (ja)	2010-05-25	2011-12-01	株式会社ゲノム創薬研究所	新規環状ペプチド化合物とその製造方法及び感染症治療薬、抗生物質含有画分、その抗生物質及びその抗生物質の製造方法並びに抗生物質産生微生物及びそれが産生した抗生物質
JP5878303B2 (ja) *	2010-05-25	2016-03-08	株式会社ゲノム創薬研究所	抗生物質含有画分、その抗生物質及びその抗生物質の製造方法
JP5823733B2 (ja) *	2010-05-25	2015-11-25	株式会社ゲノム創薬研究所	抗生物質産生微生物及びそれが産生した抗生物質
JP5878302B2 (ja) *	2010-05-25	2016-03-08	株式会社ゲノム創薬研究所	新規環状ペプチド化合物とその製造方法及び感染症治療薬
BRPI1005341B1 (pt) *	2010-12-02	2016-12-20	Bosch Do Brasil	galeria de combustível de material plástico com sistema de aquecimento
JPWO2012176909A1 (ja) *	2011-06-24	2015-02-23	公益財団法人微生物化学研究会	トリプロペプチン誘導体又はその薬理学上許容される塩、及び抗菌剤
EP2790514A1 (de)	2011-12-14	2014-10-22	Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V.	Verfahren zum abbau eines biofilms auf oberflächen von objekten
WO2014028848A1 (en) *	2012-08-17	2014-02-20	The Regents Of The University Of Michigan	Compositions and method for treating neutralizing microorganisms
US11744859B2 (en)	2017-07-07	2023-09-05	Epicentrx, Inc.	Compositions and methods for parenteral administration of therapeutic agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1266247C (en) *	1985-03-25	1990-02-27		ANTIBIOTIC PREPARED BY LYSOBACTER SP. SC14.067

2001
- 2001-03-28 EP EP01917554A patent/EP1285928B1/de not_active Expired - Lifetime
- 2001-03-28 JP JP2001572539A patent/JP4054576B2/ja not_active Expired - Fee Related
- 2001-03-28 US US10/239,324 patent/US7271147B2/en not_active Expired - Fee Related
- 2001-03-28 ES ES01917554T patent/ES2240434T3/es not_active Expired - Lifetime
- 2001-03-28 AT AT01917554T patent/ATE295852T1/de not_active IP Right Cessation
- 2001-03-28 DE DE60110908T patent/DE60110908T2/de not_active Expired - Lifetime
- 2001-03-28 AU AU2001244594A patent/AU2001244594A1/en not_active Abandoned
- 2001-03-28 WO PCT/JP2001/002578 patent/WO2001074850A1/ja not_active Ceased

Also Published As

Publication number	Publication date
US20030162697A1 (en)	2003-08-28
US7271147B2 (en)	2007-09-18
ES2240434T3 (es)	2005-10-16
AU2001244594A1 (en)	2001-10-15
WO2001074850A1 (en)	2001-10-11
EP1285928A1 (de)	2003-02-26
EP1285928A4 (de)	2004-09-01
DE60110908T2 (de)	2006-01-19
JP4054576B2 (ja)	2008-02-27
DE60110908D1 (de)	2005-06-23
EP1285928B1 (de)	2005-05-18

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Legal Events

Date	Code	Title	Description
2005-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties