ATE302746T1 - Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen - Google Patents

Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen

Info

Publication number
ATE302746T1
ATE302746T1 AT00949202T AT00949202T ATE302746T1 AT E302746 T1 ATE302746 T1 AT E302746T1 AT 00949202 T AT00949202 T AT 00949202T AT 00949202 T AT00949202 T AT 00949202T AT E302746 T1 ATE302746 T1 AT E302746T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
nitric esters
amorphous
amorphous nitric
esters
Prior art date
Application number
AT00949202T
Other languages
English (en)
Inventor
Francesca Benedini
Patrizia Antognazza
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Application granted granted Critical
Publication of ATE302746T1 publication Critical patent/ATE302746T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT00949202T 1999-06-24 2000-06-21 Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen ATE302746T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche
PCT/EP2000/005723 WO2001000563A1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE302746T1 true ATE302746T1 (de) 2005-09-15

Family

ID=11383219

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00949202T ATE302746T1 (de) 1999-06-24 2000-06-21 Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen

Country Status (23)

Country Link
US (1) US6753442B1 (de)
EP (1) EP1187803B1 (de)
JP (1) JP2003503380A (de)
KR (1) KR100672001B1 (de)
CN (1) CN1187312C (de)
AT (1) ATE302746T1 (de)
AU (1) AU781479B2 (de)
BR (1) BR0011831A (de)
CA (1) CA2377132A1 (de)
DE (1) DE60022188T2 (de)
DK (1) DK1187803T3 (de)
ES (1) ES2246878T3 (de)
HU (1) HUP0201721A3 (de)
IL (1) IL146789A0 (de)
IT (1) IT1312115B1 (de)
MX (1) MXPA01013273A (de)
NO (1) NO321523B1 (de)
NZ (1) NZ515757A (de)
PL (1) PL195557B1 (de)
RU (1) RU2248963C2 (de)
TR (1) TR200103624T2 (de)
WO (1) WO2001000563A1 (de)
ZA (1) ZA200109862B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649629B2 (en) 1999-12-23 2003-11-18 Nitromed, Inc. Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
DE60122939T2 (de) 2000-12-21 2007-01-11 Nitromed, Inc., Bedford Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren
EP1219306A1 (de) * 2000-12-29 2002-07-03 Nicox S.A. Zyklodextrin und NO-abgebende Arzneimittlen enthaltende Zusammensetzungen
US7220749B2 (en) 2002-06-11 2007-05-22 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
WO2004004648A2 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
AU2003261281A1 (en) 2002-07-29 2004-02-16 Nicox S.A. Cyclooxygenase- 2 selective inhibitors, compositions and methods of use
EP1558582B1 (de) 2003-07-22 2005-12-21 Arena Pharmaceuticals, Inc. Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
US9567327B2 (en) 2007-08-15 2017-02-14 Arena Pharmaceuticals, Inc. Imidazo[1,2-a]pyridine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
JP5524851B2 (ja) * 2007-10-17 2014-06-18 エフ． オボカイティス，トッド 室温で安定な非結晶アスピリン
WO2009052246A1 (en) * 2007-10-17 2009-04-23 Ovokaitys, Todd, F. Process for the modification of the solid state of a compound and co-amorphous compositions produced with same
ES2324007A1 (es) * 2007-10-25 2009-07-28 Ferrer Internacional, S.A. Una forma amorfa de un compuesto antiinflamatorio.
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
WO2010062321A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
TR201805216T4 (en) 2008-10-28 2018-06-21 Arena Pharm Inc COMPOSITIONS OF A USEFUL 5-HT2A SEROTONINE RECEPTOR MODULATOR FOR THE TREATMENT OF RELATED DISORDERS
CN102186933B (zh) 2008-11-04 2014-06-25 帝斯曼知识产权资产管理有限公司 光纤用的d 1413 ht可辐射固化涂层
US10202598B2 (en) 2014-05-30 2019-02-12 Todd Frank Ovokaitys Methods and systems for generation, use, and delivery of activated stem cells
US10384985B2 (en) 2014-06-06 2019-08-20 B.K. Consultants, Inc. Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants
WO2015187974A1 (en) 2014-06-06 2015-12-10 Ovokaitys Todd Frank Methods and compositions for increasing the bioactivity of nutrients
HK1245660A1 (zh) 2015-06-12 2018-08-31 Axovant Sciences Gmbh 有用於预防和治疗rem睡眠行为障碍的二芳基脲和芳基脲衍生物
WO2017011767A2 (en) 2015-07-15 2017-01-19 Axovant Sciences Ltd. Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease
AU2021397627A1 (en) 2020-12-08 2023-07-20 Todd Frank OVOKAITYS Methods and systems for increased production of stem cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
IT1256345B (it) * 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) * 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
JP4043046B2 (ja) * 1994-05-10 2008-02-06 ニコックス エス エイ 消炎、鎮痛および抗血栓活性を有するニトロ化合物およびそれらの組成物
IT1276071B1 (it) * 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
NO321523B1 (no) 2006-05-15
ITMI991402A1 (it) 2000-12-24
WO2001000563A1 (en) 2001-01-04
ES2246878T3 (es) 2006-03-01
ITMI991402A0 (it) 1999-06-24
EP1187803B1 (de) 2005-08-24
CA2377132A1 (en) 2001-01-04
EP1187803A1 (de) 2002-03-20
TR200103624T2 (tr) 2002-04-22
RU2248963C2 (ru) 2005-03-27
NO20016232L (no) 2001-12-19
DK1187803T3 (da) 2005-11-28
CN1187312C (zh) 2005-02-02
PL352529A1 (en) 2003-08-25
AU6264400A (en) 2001-01-31
MXPA01013273A (es) 2003-07-14
HUP0201721A2 (en) 2002-10-28
ZA200109862B (en) 2003-05-28
CN1356975A (zh) 2002-07-03
DE60022188D1 (de) 2005-09-29
NO20016232D0 (no) 2001-12-19
US6753442B1 (en) 2004-06-22
IT1312115B1 (it) 2002-04-04
BR0011831A (pt) 2002-03-19
AU781479B2 (en) 2005-05-26
KR20020008220A (ko) 2002-01-29
PL195557B1 (pl) 2007-10-31
KR100672001B1 (ko) 2007-01-19
DE60022188T2 (de) 2006-06-08
NZ515757A (en) 2004-02-27
HUP0201721A3 (en) 2003-08-28
IL146789A0 (en) 2002-07-25
JP2003503380A (ja) 2003-01-28

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