ATE302746T1 - Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen - Google Patents

Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen

Info

Publication number
ATE302746T1
ATE302746T1 AT00949202T AT00949202T ATE302746T1 AT E302746 T1 ATE302746 T1 AT E302746T1 AT 00949202 T AT00949202 T AT 00949202T AT 00949202 T AT00949202 T AT 00949202T AT E302746 T1 ATE302746 T1 AT E302746T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
nitric esters
amorphous
amorphous nitric
esters
Prior art date
Application number
AT00949202T
Other languages
English (en)
Inventor
Francesca Benedini
Patrizia Antognazza
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Application granted granted Critical
Publication of ATE302746T1 publication Critical patent/ATE302746T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT00949202T 1999-06-24 2000-06-21 Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen ATE302746T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche
PCT/EP2000/005723 WO2001000563A1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE302746T1 true ATE302746T1 (de) 2005-09-15

Family

ID=11383219

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00949202T ATE302746T1 (de) 1999-06-24 2000-06-21 Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen

Country Status (23)

Country Link
US (1) US6753442B1 (de)
EP (1) EP1187803B1 (de)
JP (1) JP2003503380A (de)
KR (1) KR100672001B1 (de)
CN (1) CN1187312C (de)
AT (1) ATE302746T1 (de)
AU (1) AU781479B2 (de)
BR (1) BR0011831A (de)
CA (1) CA2377132A1 (de)
DE (1) DE60022188T2 (de)
DK (1) DK1187803T3 (de)
ES (1) ES2246878T3 (de)
HU (1) HUP0201721A3 (de)
IL (1) IL146789A0 (de)
IT (1) IT1312115B1 (de)
MX (1) MXPA01013273A (de)
NO (1) NO321523B1 (de)
NZ (1) NZ515757A (de)
PL (1) PL195557B1 (de)
RU (1) RU2248963C2 (de)
TR (1) TR200103624T2 (de)
WO (1) WO2001000563A1 (de)
ZA (1) ZA200109862B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2002002582A0 (en) 1999-12-23 2002-09-30 Nitromed Inc Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
DE60122939T2 (de) 2000-12-21 2007-01-11 Nitromed, Inc., Bedford Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren
EP1219306A1 (de) * 2000-12-29 2002-07-03 Nicox S.A. Zyklodextrin und NO-abgebende Arzneimittlen enthaltende Zusammensetzungen
CA2487414A1 (en) 2002-06-11 2003-12-18 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
AU2003247792B2 (en) 2002-07-03 2009-09-24 Nicox S.A. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
US7244753B2 (en) 2002-07-29 2007-07-17 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
DE602004000260T2 (de) 2003-07-22 2006-08-24 Arena Pharmaceuticals, Inc., San Diego Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
JP5393677B2 (ja) 2007-08-15 2014-01-22 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ＨＴ２Ａセロトニン受容体に関連した障害の治療のための５−ＨＴ２Ａセロトニン受容体のモジュレーターとしてのイミダゾ［１，２−ａ］ピリジン誘導体
EP2211611B1 (de) * 2007-10-17 2014-12-10 Todd F. Ovokaitys Verfahren zum modifizieren des festen aggregatszustands einer verbindung und hiermit hergestellte co-amorphe zusammensetzungen
WO2009052248A1 (en) * 2007-10-17 2009-04-23 Strachan, John, Scott Room temperature stable non-crystalline aspirin
ES2324007A1 (es) * 2007-10-25 2009-07-28 Ferrer Internacional, S.A. Una forma amorfa de un compuesto antiinflamatorio.
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
CA2741731A1 (en) * 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Compositions of a 5-ht2a serotonin receptor modulator useful for the treatment of disorders related thereto
JP5392868B2 (ja) 2008-11-04 2014-01-22 ディーエスエム アイピー アセッツ ビー．ブイ． 光ファイバ用ｄ１４１３ｈｔ放射線硬化性コーティング
US10202598B2 (en) 2014-05-30 2019-02-12 Todd Frank Ovokaitys Methods and systems for generation, use, and delivery of activated stem cells
WO2015187974A1 (en) 2014-06-06 2015-12-10 Ovokaitys Todd Frank Methods and compositions for increasing the bioactivity of nutrients
US10384985B2 (en) 2014-06-06 2019-08-20 B.K. Consultants, Inc. Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants
US10022355B2 (en) 2015-06-12 2018-07-17 Axovant Sciences Gmbh Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of REM sleep behavior disorder
BR112018000728A2 (pt) 2015-07-15 2018-09-04 Axovant Sciences Gmbh resumo método para a profilaxia e/ou tratamento de alucinações visuais em um sujeito com necessidade do mesmo
US12246037B2 (en) 2020-12-08 2025-03-11 Todd Frank Ovokaitys Methods and systems for increased production of stem cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
IT1256345B (it) 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
WO1995030641A1 (en) * 1994-05-10 1995-11-16 Nicox S.A. Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities
IT1276071B1 (it) * 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
DK1187803T3 (da) 2005-11-28
ES2246878T3 (es) 2006-03-01
CN1356975A (zh) 2002-07-03
MXPA01013273A (es) 2003-07-14
NZ515757A (en) 2004-02-27
CA2377132A1 (en) 2001-01-04
NO321523B1 (no) 2006-05-15
AU6264400A (en) 2001-01-31
IL146789A0 (en) 2002-07-25
AU781479B2 (en) 2005-05-26
EP1187803A1 (de) 2002-03-20
DE60022188D1 (de) 2005-09-29
US6753442B1 (en) 2004-06-22
PL195557B1 (pl) 2007-10-31
TR200103624T2 (tr) 2002-04-22
PL352529A1 (en) 2003-08-25
ITMI991402A0 (it) 1999-06-24
CN1187312C (zh) 2005-02-02
ZA200109862B (en) 2003-05-28
RU2248963C2 (ru) 2005-03-27
NO20016232D0 (no) 2001-12-19
HUP0201721A3 (en) 2003-08-28
KR100672001B1 (ko) 2007-01-19
EP1187803B1 (de) 2005-08-24
ITMI991402A1 (it) 2000-12-24
JP2003503380A (ja) 2003-01-28
IT1312115B1 (it) 2002-04-04
HUP0201721A2 (en) 2002-10-28
DE60022188T2 (de) 2006-06-08
BR0011831A (pt) 2002-03-19
KR20020008220A (ko) 2002-01-29
NO20016232L (no) 2001-12-19
WO2001000563A1 (en) 2001-01-04

Similar Documents

Publication Publication Date Title
ATE302746T1 (de) Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen
ATE312613T1 (de) Niedrig dosierte entecavir formulierung und deren verwendung
NZ324887A (en) Piperazine and piperidine compounds with analgesic effect
DE69907977D1 (de) Pyrrolobenzodiazepine
HUP0204071A3 (en) Nitrogenous cyclic compounds and pharmaceutical compositions containing the same and their use
IL163552A (en) Conjugates of biologically active compounds, uses thereof and pharmaceutical compositions comprising the same
BR0107869A (pt) Composições farmacêuticas eletrogiradas
DE60133665D1 (de) Zusammensetzungen enthaltend verzweigte primäre alkohole und deren derivate
MA26882A1 (fr) COMPOSITIONS PHARMACEUTIQUES D'INHIBITEURS ET GLYCOGèNE-PHOSPHORYLASE
DK1246625T3 (da) Anvendelser og sammensætninger af nitratestere til tilvejebringelse af sedering
ATE402691T1 (de) Pharmazeutische zusammensetzungen zur oralen und topischen verabreichung
DE60037816D1 (de) Pharmazeutische formulierung enthaltend megalatran und dessen pro-pharmaka
MXPA02012160A (es) Composiciones medicinales las cuales contienen derivados de propenona.
EP1221926A4 (de) Pharmazeutische zusammensetzungen mit schlecht löslichen arzneimittelwirkstoffen
SE0003476D0 (sv) Compounds
HUP0303673A3 (en) Piperidine derivatives and pharmaceutical compositions containing these derivatives as the active ingredient
DE60024476D1 (de) Pedikulizide und veterinärmedizinische zusammensetzungen
ATE301463T1 (de) Pharmazeutische zusammensetzungen enthaltend 17alpha-furanylester von 17beta-carbothioat androstanderivaten und einen muskarinrezeptorantagonist
ATE290543T1 (de) Pharmazeutische zusammensetzungen mit oligosacchariden und deren herstellung
ATE236885T1 (de) Hydrazono-benzazulen-derivate, pharmazeutische zusammensetzungen und zwischenprodukte
ATE332140T1 (de) Pharmazeutische zusammensetzungen, welche steroidische strukturen enthalten, und deren verwendungen
ATE350064T1 (de) Pharmazeutische zusammensetzungen von rapamycines
IL169163A0 (en) Optically active dihydropyridine derivative and pharmaceutical compositions containing the same
ATE279927T1 (de) Pharmazeutische zusammensetzungen enthaltend tobramycin und xanthangummi
ITMI20001741A0 (it) Composizioni farmaceutiche comprendenti agenti antiinfiammatori e loro usi

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1187803

Country of ref document: EP

REN Ceased due to non-payment of the annual fee