ITMI991402A0 - Composti amorfi e relative composizioni farmaceutiche - Google Patents

Composti amorfi e relative composizioni farmaceutiche

Info

Publication number
ITMI991402A0
ITMI991402A0 IT99MI001402A ITMI991402A ITMI991402A0 IT MI991402 A0 ITMI991402 A0 IT MI991402A0 IT 99MI001402 A IT99MI001402 A IT 99MI001402A IT MI991402 A ITMI991402 A IT MI991402A IT MI991402 A0 ITMI991402 A0 IT MI991402A0
Authority
IT
Italy
Prior art keywords
pharmaceutical compositions
amorphous compounds
related pharmaceutical
amorphous
compounds
Prior art date
Application number
IT99MI001402A
Other languages
English (en)
Inventor
Francesca Benedini
Patrizia Antognazza
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of ITMI991402A0 publication Critical patent/ITMI991402A0/it
Priority to IT1999MI001402A priority Critical patent/IT1312115B1/it
Priority to AT00949202T priority patent/ATE302746T1/de
Priority to DK00949202T priority patent/DK1187803T3/da
Priority to IL14678900A priority patent/IL146789A0/xx
Priority to CNB008091919A priority patent/CN1187312C/zh
Priority to CA002377132A priority patent/CA2377132A1/en
Priority to NZ515757A priority patent/NZ515757A/xx
Priority to TR2001/03624T priority patent/TR200103624T2/xx
Priority to MXPA01013273A priority patent/MXPA01013273A/es
Priority to BR0011831-1A priority patent/BR0011831A/pt
Priority to PCT/EP2000/005723 priority patent/WO2001000563A1/en
Priority to DE60022188T priority patent/DE60022188T2/de
Priority to EP00949202A priority patent/EP1187803B1/en
Priority to ES00949202T priority patent/ES2246878T3/es
Priority to RU2001134613/04A priority patent/RU2248963C2/ru
Priority to AU62644/00A priority patent/AU781479B2/en
Priority to KR1020017015729A priority patent/KR100672001B1/ko
Priority to PL00352529A priority patent/PL195557B1/pl
Priority to US10/009,741 priority patent/US6753442B1/en
Priority to JP2001506976A priority patent/JP2003503380A/ja
Priority to SI200030758T priority patent/SI1187803T1/sl
Priority to HU0201721A priority patent/HUP0201721A3/hu
Publication of ITMI991402A1 publication Critical patent/ITMI991402A1/it
Priority to ZA200109862A priority patent/ZA200109862B/xx
Priority to NO20016232A priority patent/NO321523B1/no
Application granted granted Critical
Publication of IT1312115B1 publication Critical patent/IT1312115B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT1999MI001402A 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche IT1312115B1 (it)

Priority Applications (24)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche
EP00949202A EP1187803B1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
RU2001134613/04A RU2248963C2 (ru) 1999-06-24 2000-06-21 Способ получения фармацевтической композиции, обладающей противовоспалительной и анальгезирующей активностью, включающей аморфные нитроэфиры
IL14678900A IL146789A0 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
CNB008091919A CN1187312C (zh) 1999-06-24 2000-06-21 无定形化合物和它们的药物组合物
CA002377132A CA2377132A1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
NZ515757A NZ515757A (en) 1999-06-24 2000-06-21 Amorphous compounds and their pharmaceutical compositions
TR2001/03624T TR200103624T2 (tr) 1999-06-24 2000-06-21 Amof bileşikler ve bunların farmasötik bileşimleri.
MXPA01013273A MXPA01013273A (es) 1999-06-24 2000-06-21 Compuestos amorfos y sus composiciones farmaceuticas.
BR0011831-1A BR0011831A (pt) 1999-06-24 2000-06-21 Compostos, processo para preparar os mesmos, composições farmacêuticas, e, uso dos compostos
PCT/EP2000/005723 WO2001000563A1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
DE60022188T DE60022188T2 (de) 1999-06-24 2000-06-21 Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen
AT00949202T ATE302746T1 (de) 1999-06-24 2000-06-21 Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen
ES00949202T ES2246878T3 (es) 1999-06-24 2000-06-21 Esteres nitricos amorfos y sus composiciones farmaceuticas.
DK00949202T DK1187803T3 (da) 1999-06-24 2000-06-21 Amorfe salpetersyreestere og deres farmaceutiske sammensætninger
AU62644/00A AU781479B2 (en) 1999-06-24 2000-06-21 Amorphous compounds and their pharmaceutical compositions
KR1020017015729A KR100672001B1 (ko) 1999-06-24 2000-06-21 무정형 질산에스테르들 및 그의 약학조성물들
PL00352529A PL195557B1 (pl) 1999-06-24 2000-06-21 Kompozycja zawierająca nitroksyzwiązek, sposób jej wytwarzania i zawierająca ją kompozycja farmaceutyczna
US10/009,741 US6753442B1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
JP2001506976A JP2003503380A (ja) 1999-06-24 2000-06-21 無定形硝酸エステルおよびその製剤組成物
SI200030758T SI1187803T1 (sl) 1999-06-24 2000-06-21 Amorfni dusikovi estri in njihovi farmacevtski sestavki
HU0201721A HUP0201721A3 (en) 1999-06-24 2000-06-21 Amorphous nitric esters, process for producing them and their pharmaceutical compositions
ZA200109862A ZA200109862B (en) 1999-06-24 2001-11-29 Amorphous nitric esters and their pharmaceutical compositions.
NO20016232A NO321523B1 (no) 1999-06-24 2001-12-19 Preparat omfattende et nitroksyderivat, farmasoytisk formulering inneholdende dette og fremgangsmate for fremstilling av preparatet.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche

Publications (3)

Publication Number Publication Date
ITMI991402A0 true ITMI991402A0 (it) 1999-06-24
ITMI991402A1 ITMI991402A1 (it) 2000-12-24
IT1312115B1 IT1312115B1 (it) 2002-04-04

Family

ID=11383219

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche

Country Status (23)

Country Link
US (1) US6753442B1 (it)
EP (1) EP1187803B1 (it)
JP (1) JP2003503380A (it)
KR (1) KR100672001B1 (it)
CN (1) CN1187312C (it)
AT (1) ATE302746T1 (it)
AU (1) AU781479B2 (it)
BR (1) BR0011831A (it)
CA (1) CA2377132A1 (it)
DE (1) DE60022188T2 (it)
DK (1) DK1187803T3 (it)
ES (1) ES2246878T3 (it)
HU (1) HUP0201721A3 (it)
IL (1) IL146789A0 (it)
IT (1) IT1312115B1 (it)
MX (1) MXPA01013273A (it)
NO (1) NO321523B1 (it)
NZ (1) NZ515757A (it)
PL (1) PL195557B1 (it)
RU (1) RU2248963C2 (it)
TR (1) TR200103624T2 (it)
WO (1) WO2001000563A1 (it)
ZA (1) ZA200109862B (it)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL150368A0 (en) 1999-12-23 2002-12-01 Nitromed Inc Nitrosated and nitrosylated cyclooxygenase-2-inhibitors, compositions and methods of use
IT1319202B1 (it) 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
JP4092203B2 (ja) 2000-12-21 2008-05-28 ニトロメッド，インク． 新規のシクロオキシゲナーゼ２選択的阻害剤としての置換アリール化合物、組成物、および使用方法
EP1219306A1 (en) 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
CA2487414A1 (en) 2002-06-11 2003-12-18 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
CA2491127A1 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
JP2005538110A (ja) 2002-07-29 2005-12-15 ニトロメッド インコーポレーティッド シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法
US8754238B2 (en) 2003-07-22 2014-06-17 Arena Pharmaceuticals, Inc. Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
JP5393677B2 (ja) 2007-08-15 2014-01-22 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ＨＴ２Ａセロトニン受容体に関連した障害の治療のための５−ＨＴ２Ａセロトニン受容体のモジュレーターとしてのイミダゾ［１，２−ａ］ピリジン誘導体
CN101969766B (zh) * 2007-10-17 2015-05-06 托德·F·奥沃凯泰斯 固态化合物的改良方法及使用其制备的共-无定形组合物
EA027333B1 (ru) * 2007-10-17 2017-07-31 Тодд Ф. Овокайтис Стабильный при комнатной температуре некристаллический аспирин
ES2324007A1 (es) * 2007-10-25 2009-07-28 Ferrer Internacional, S.A. Una forma amorfa de un compuesto antiinflamatorio.
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
WO2010062321A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
HRP20180589T1 (hr) * 2008-10-28 2018-05-18 Arena Pharmaceuticals, Inc. Pripravci modulatora serotoninskog receptora 5-ht2a koji su korisni za liječenje s njim povezanih poremećaja
US8218931B2 (en) 2008-11-04 2012-07-10 Dsm Ip Assets B.V. D 1413 HT radiation curable coatings for optical fiber
US10202598B2 (en) 2014-05-30 2019-02-12 Todd Frank Ovokaitys Methods and systems for generation, use, and delivery of activated stem cells
US10384985B2 (en) 2014-06-06 2019-08-20 B.K. Consultants, Inc. Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants
WO2015187974A1 (en) 2014-06-06 2015-12-10 Ovokaitys Todd Frank Methods and compositions for increasing the bioactivity of nutrients
RU2017145976A (ru) 2015-06-12 2019-07-15 Аксовант Сайенсиз Гмбх Производные диарил- и арилгетероарилмочевины, применимые для профилактики и лечения нарушения поведения во время REM-фазы сна
TW201720439A (zh) 2015-07-15 2017-06-16 Axovant Sciences Gmbh 用於預防及治療與神經退化性疾病相關的幻覺之作為５－ｈｔ２ａ血清素受體的二芳基及芳基雜芳基脲衍生物
MX2023006721A (es) 2020-12-08 2023-07-04 Todd Frank Ovokaitys Metodos y sistemas para producción incrementada de celulas madre.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
IT1256345B (it) * 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) * 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
WO1995030641A1 (en) 1994-05-10 1995-11-16 Nicox S.A. Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities
IT1276071B1 (it) * 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
JP2003503380A (ja) 2003-01-28
HUP0201721A2 (en) 2002-10-28
KR100672001B1 (ko) 2007-01-19
CA2377132A1 (en) 2001-01-04
BR0011831A (pt) 2002-03-19
EP1187803B1 (en) 2005-08-24
DE60022188T2 (de) 2006-06-08
ATE302746T1 (de) 2005-09-15
TR200103624T2 (tr) 2002-04-22
RU2248963C2 (ru) 2005-03-27
AU6264400A (en) 2001-01-31
CN1187312C (zh) 2005-02-02
IT1312115B1 (it) 2002-04-04
EP1187803A1 (en) 2002-03-20
PL352529A1 (en) 2003-08-25
NO321523B1 (no) 2006-05-15
DE60022188D1 (de) 2005-09-29
IL146789A0 (en) 2002-07-25
NZ515757A (en) 2004-02-27
NO20016232D0 (no) 2001-12-19
MXPA01013273A (es) 2003-07-14
PL195557B1 (pl) 2007-10-31
CN1356975A (zh) 2002-07-03
DK1187803T3 (da) 2005-11-28
NO20016232L (no) 2001-12-19
HUP0201721A3 (en) 2003-08-28
AU781479B2 (en) 2005-05-26
ITMI991402A1 (it) 2000-12-24
US6753442B1 (en) 2004-06-22
ZA200109862B (en) 2003-05-28
WO2001000563A1 (en) 2001-01-04
ES2246878T3 (es) 2006-03-01
KR20020008220A (ko) 2002-01-29

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