ITMI991402A0 - Composti amorfi e relative composizioni farmaceutiche - Google Patents

Composti amorfi e relative composizioni farmaceutiche

Info

Publication number
ITMI991402A0
ITMI991402A0 IT99MI001402A ITMI991402A ITMI991402A0 IT MI991402 A0 ITMI991402 A0 IT MI991402A0 IT 99MI001402 A IT99MI001402 A IT 99MI001402A IT MI991402 A ITMI991402 A IT MI991402A IT MI991402 A0 ITMI991402 A0 IT MI991402A0
Authority
IT
Italy
Prior art keywords
pharmaceutical compositions
amorphous compounds
related pharmaceutical
amorphous
compounds
Prior art date
Application number
IT99MI001402A
Other languages
English (en)
Inventor
Francesca Benedini
Patrizia Antognazza
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of ITMI991402A0 publication Critical patent/ITMI991402A0/it
Priority to IT1999MI001402A priority Critical patent/IT1312115B1/it
Priority to KR1020017015729A priority patent/KR100672001B1/ko
Priority to SI200030758T priority patent/SI1187803T1/sl
Priority to NZ515757A priority patent/NZ515757A/xx
Priority to MXPA01013273A priority patent/MXPA01013273A/es
Priority to IL14678900A priority patent/IL146789A0/xx
Priority to DK00949202T priority patent/DK1187803T3/da
Priority to DE60022188T priority patent/DE60022188T2/de
Priority to EP00949202A priority patent/EP1187803B1/en
Priority to BR0011831-1A priority patent/BR0011831A/pt
Priority to PCT/EP2000/005723 priority patent/WO2001000563A1/en
Priority to AT00949202T priority patent/ATE302746T1/de
Priority to US10/009,741 priority patent/US6753442B1/en
Priority to PL00352529A priority patent/PL195557B1/pl
Priority to RU2001134613/04A priority patent/RU2248963C2/ru
Priority to JP2001506976A priority patent/JP2003503380A/ja
Priority to HU0201721A priority patent/HUP0201721A3/hu
Priority to CNB008091919A priority patent/CN1187312C/zh
Priority to ES00949202T priority patent/ES2246878T3/es
Priority to TR2001/03624T priority patent/TR200103624T2/xx
Priority to AU62644/00A priority patent/AU781479B2/en
Priority to CA002377132A priority patent/CA2377132A1/en
Publication of ITMI991402A1 publication Critical patent/ITMI991402A1/it
Priority to ZA200109862A priority patent/ZA200109862B/xx
Priority to NO20016232A priority patent/NO321523B1/no
Application granted granted Critical
Publication of IT1312115B1 publication Critical patent/IT1312115B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT1999MI001402A 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche IT1312115B1 (it)

Priority Applications (24)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche
US10/009,741 US6753442B1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
RU2001134613/04A RU2248963C2 (ru) 1999-06-24 2000-06-21 Способ получения фармацевтической композиции, обладающей противовоспалительной и анальгезирующей активностью, включающей аморфные нитроэфиры
NZ515757A NZ515757A (en) 1999-06-24 2000-06-21 Amorphous compounds and their pharmaceutical compositions
MXPA01013273A MXPA01013273A (es) 1999-06-24 2000-06-21 Compuestos amorfos y sus composiciones farmaceuticas.
IL14678900A IL146789A0 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
DK00949202T DK1187803T3 (da) 1999-06-24 2000-06-21 Amorfe salpetersyreestere og deres farmaceutiske sammensætninger
DE60022188T DE60022188T2 (de) 1999-06-24 2000-06-21 Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen
EP00949202A EP1187803B1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
BR0011831-1A BR0011831A (pt) 1999-06-24 2000-06-21 Compostos, processo para preparar os mesmos, composições farmacêuticas, e, uso dos compostos
PCT/EP2000/005723 WO2001000563A1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
AT00949202T ATE302746T1 (de) 1999-06-24 2000-06-21 Amorphe salpetersäureester und deren pharmazeutische zusammensetzungen
KR1020017015729A KR100672001B1 (ko) 1999-06-24 2000-06-21 무정형 질산에스테르들 및 그의 약학조성물들
PL00352529A PL195557B1 (pl) 1999-06-24 2000-06-21 Kompozycja zawierająca nitroksyzwiązek, sposób jej wytwarzania i zawierająca ją kompozycja farmaceutyczna
SI200030758T SI1187803T1 (sl) 1999-06-24 2000-06-21 Amorfni dusikovi estri in njihovi farmacevtski sestavki
JP2001506976A JP2003503380A (ja) 1999-06-24 2000-06-21 無定形硝酸エステルおよびその製剤組成物
HU0201721A HUP0201721A3 (en) 1999-06-24 2000-06-21 Amorphous nitric esters, process for producing them and their pharmaceutical compositions
CNB008091919A CN1187312C (zh) 1999-06-24 2000-06-21 无定形化合物和它们的药物组合物
ES00949202T ES2246878T3 (es) 1999-06-24 2000-06-21 Esteres nitricos amorfos y sus composiciones farmaceuticas.
TR2001/03624T TR200103624T2 (tr) 1999-06-24 2000-06-21 Amof bileşikler ve bunların farmasötik bileşimleri.
AU62644/00A AU781479B2 (en) 1999-06-24 2000-06-21 Amorphous compounds and their pharmaceutical compositions
CA002377132A CA2377132A1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions
ZA200109862A ZA200109862B (en) 1999-06-24 2001-11-29 Amorphous nitric esters and their pharmaceutical compositions.
NO20016232A NO321523B1 (no) 1999-06-24 2001-12-19 Preparat omfattende et nitroksyderivat, farmasoytisk formulering inneholdende dette og fremgangsmate for fremstilling av preparatet.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche

Publications (3)

Publication Number Publication Date
ITMI991402A0 true ITMI991402A0 (it) 1999-06-24
ITMI991402A1 ITMI991402A1 (it) 2000-12-24
IT1312115B1 IT1312115B1 (it) 2002-04-04

Family

ID=11383219

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche

Country Status (23)

Country Link
US (1) US6753442B1 (it)
EP (1) EP1187803B1 (it)
JP (1) JP2003503380A (it)
KR (1) KR100672001B1 (it)
CN (1) CN1187312C (it)
AT (1) ATE302746T1 (it)
AU (1) AU781479B2 (it)
BR (1) BR0011831A (it)
CA (1) CA2377132A1 (it)
DE (1) DE60022188T2 (it)
DK (1) DK1187803T3 (it)
ES (1) ES2246878T3 (it)
HU (1) HUP0201721A3 (it)
IL (1) IL146789A0 (it)
IT (1) IT1312115B1 (it)
MX (1) MXPA01013273A (it)
NO (1) NO321523B1 (it)
NZ (1) NZ515757A (it)
PL (1) PL195557B1 (it)
RU (1) RU2248963C2 (it)
TR (1) TR200103624T2 (it)
WO (1) WO2001000563A1 (it)
ZA (1) ZA200109862B (it)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2002002582A0 (en) 1999-12-23 2002-09-30 Nitromed Inc Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
DE60122939T2 (de) 2000-12-21 2007-01-11 Nitromed, Inc., Bedford Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren
EP1219306A1 (en) * 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
CA2487414A1 (en) 2002-06-11 2003-12-18 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
AU2003247792B2 (en) 2002-07-03 2009-09-24 Nicox S.A. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
US7244753B2 (en) 2002-07-29 2007-07-17 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
DE602004000260T2 (de) 2003-07-22 2006-08-24 Arena Pharmaceuticals, Inc., San Diego Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
JP5393677B2 (ja) 2007-08-15 2014-01-22 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ＨＴ２Ａセロトニン受容体に関連した障害の治療のための５−ＨＴ２Ａセロトニン受容体のモジュレーターとしてのイミダゾ［１，２−ａ］ピリジン誘導体
EP2211611B1 (en) * 2007-10-17 2014-12-10 Todd F. Ovokaitys Process for the modification of the solid state of a compound and co-amorphous compositions produced with same
WO2009052248A1 (en) * 2007-10-17 2009-04-23 Strachan, John, Scott Room temperature stable non-crystalline aspirin
ES2324007A1 (es) * 2007-10-25 2009-07-28 Ferrer Internacional, S.A. Una forma amorfa de un compuesto antiinflamatorio.
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
CA2741731A1 (en) * 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Compositions of a 5-ht2a serotonin receptor modulator useful for the treatment of disorders related thereto
JP5392868B2 (ja) 2008-11-04 2014-01-22 ディーエスエム アイピー アセッツ ビー．ブイ． 光ファイバ用ｄ１４１３ｈｔ放射線硬化性コーティング
US10202598B2 (en) 2014-05-30 2019-02-12 Todd Frank Ovokaitys Methods and systems for generation, use, and delivery of activated stem cells
WO2015187974A1 (en) 2014-06-06 2015-12-10 Ovokaitys Todd Frank Methods and compositions for increasing the bioactivity of nutrients
US10384985B2 (en) 2014-06-06 2019-08-20 B.K. Consultants, Inc. Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants
US10022355B2 (en) 2015-06-12 2018-07-17 Axovant Sciences Gmbh Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of REM sleep behavior disorder
BR112018000728A2 (pt) 2015-07-15 2018-09-04 Axovant Sciences Gmbh resumo método para a profilaxia e/ou tratamento de alucinações visuais em um sujeito com necessidade do mesmo
US12246037B2 (en) 2020-12-08 2025-03-11 Todd Frank Ovokaitys Methods and systems for increased production of stem cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
IT1256345B (it) 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
WO1995030641A1 (en) * 1994-05-10 1995-11-16 Nicox S.A. Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities
IT1276071B1 (it) * 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
DK1187803T3 (da) 2005-11-28
ES2246878T3 (es) 2006-03-01
CN1356975A (zh) 2002-07-03
MXPA01013273A (es) 2003-07-14
NZ515757A (en) 2004-02-27
CA2377132A1 (en) 2001-01-04
NO321523B1 (no) 2006-05-15
AU6264400A (en) 2001-01-31
IL146789A0 (en) 2002-07-25
AU781479B2 (en) 2005-05-26
EP1187803A1 (en) 2002-03-20
DE60022188D1 (de) 2005-09-29
US6753442B1 (en) 2004-06-22
PL195557B1 (pl) 2007-10-31
TR200103624T2 (tr) 2002-04-22
PL352529A1 (en) 2003-08-25
CN1187312C (zh) 2005-02-02
ZA200109862B (en) 2003-05-28
ATE302746T1 (de) 2005-09-15
RU2248963C2 (ru) 2005-03-27
NO20016232D0 (no) 2001-12-19
HUP0201721A3 (en) 2003-08-28
KR100672001B1 (ko) 2007-01-19
EP1187803B1 (en) 2005-08-24
ITMI991402A1 (it) 2000-12-24
JP2003503380A (ja) 2003-01-28
IT1312115B1 (it) 2002-04-04
HUP0201721A2 (en) 2002-10-28
DE60022188T2 (de) 2006-06-08
BR0011831A (pt) 2002-03-19
KR20020008220A (ko) 2002-01-29
NO20016232L (no) 2001-12-19
WO2001000563A1 (en) 2001-01-04

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