ATE307803T1 - Herstellung von 3-amino-2-chlor-4-methylpyridin aus aceton und ethylcyanoacetat - Google Patents
Herstellung von 3-amino-2-chlor-4-methylpyridin aus aceton und ethylcyanoacetatInfo
- Publication number
- ATE307803T1 ATE307803T1 AT00903131T AT00903131T ATE307803T1 AT E307803 T1 ATE307803 T1 AT E307803T1 AT 00903131 T AT00903131 T AT 00903131T AT 00903131 T AT00903131 T AT 00903131T AT E307803 T1 ATE307803 T1 AT E307803T1
- Authority
- AT
- Austria
- Prior art keywords
- methylpyridine
- acetone
- amino
- ethylcyanoacetate
- chlorine
- Prior art date
Links
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 title abstract 4
- ZIUSEGSNTOUIPT-UHFFFAOYSA-N ethyl 2-cyanoacetate Chemical compound CCOC(=O)CC#N ZIUSEGSNTOUIPT-UHFFFAOYSA-N 0.000 title abstract 2
- UOBCYTOUXLAABU-UHFFFAOYSA-N 2-chloro-4-methylpyridin-3-amine Chemical compound CC1=CC=NC(Cl)=C1N UOBCYTOUXLAABU-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11670399P | 1999-01-22 | 1999-01-22 | |
| PCT/US2000/000261 WO2000043364A1 (en) | 1999-01-22 | 2000-01-06 | Synthesis of 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE307803T1 true ATE307803T1 (de) | 2005-11-15 |
Family
ID=22368723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00903131T ATE307803T1 (de) | 1999-01-22 | 2000-01-06 | Herstellung von 3-amino-2-chlor-4-methylpyridin aus aceton und ethylcyanoacetat |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6136982A (de) |
| EP (1) | EP1070053B1 (de) |
| JP (1) | JP2002535310A (de) |
| AT (1) | ATE307803T1 (de) |
| CA (1) | CA2318412A1 (de) |
| DE (1) | DE60023402T2 (de) |
| ES (1) | ES2251964T3 (de) |
| WO (1) | WO2000043364A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6399781B1 (en) | 2000-10-10 | 2002-06-04 | Boehringer Ingelheim Chemicals, Inc. | Process for making 3-amino-2-chloro-4-methylpyridine |
| CN100358871C (zh) * | 2005-08-02 | 2008-01-02 | 江阴暨阳医药化工有限公司 | 氰乙酰胺和丙酮合成2-氯-3-氨基-4-甲基吡啶法 |
| US8968779B2 (en) | 2010-06-16 | 2015-03-03 | Teijin Pharma Limited | Controlled release coat-core tablet |
| WO2016118586A1 (en) * | 2015-01-20 | 2016-07-28 | Virginia Commonwealth University | Lowcost, high yield synthesis of nevirapine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3133331B2 (ja) * | 1991-06-11 | 2001-02-05 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | ３―アミノ―２―クロロ―４―アルキルピリジン類の製造方法 |
| US5654429A (en) * | 1992-11-18 | 1997-08-05 | Boehringer Ingelheim Pharma | Method for the preparation of 3-amino-2-chloro-4-alkylpyridines |
| ATE192437T1 (de) * | 1993-12-02 | 2000-05-15 | Boehringer Ingelheim Pharma | Verfahren zur herstellung von 3-amino-2-chlor-4- alkyl- bzw. 4-cycloalkyl-pyridine |
-
2000
- 2000-01-06 EP EP00903131A patent/EP1070053B1/de not_active Expired - Lifetime
- 2000-01-06 WO PCT/US2000/000261 patent/WO2000043364A1/en not_active Ceased
- 2000-01-06 ES ES00903131T patent/ES2251964T3/es not_active Expired - Lifetime
- 2000-01-06 US US09/478,588 patent/US6136982A/en not_active Expired - Lifetime
- 2000-01-06 DE DE60023402T patent/DE60023402T2/de not_active Expired - Fee Related
- 2000-01-06 AT AT00903131T patent/ATE307803T1/de not_active IP Right Cessation
- 2000-01-06 CA CA002318412A patent/CA2318412A1/en not_active Abandoned
- 2000-01-06 JP JP2000594780A patent/JP2002535310A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1070053A4 (de) | 2001-04-18 |
| DE60023402T2 (de) | 2006-04-27 |
| ES2251964T3 (es) | 2006-05-16 |
| US6136982A (en) | 2000-10-24 |
| DE60023402D1 (de) | 2005-12-01 |
| JP2002535310A (ja) | 2002-10-22 |
| EP1070053A1 (de) | 2001-01-24 |
| EP1070053B1 (de) | 2005-10-26 |
| WO2000043364A1 (en) | 2000-07-27 |
| CA2318412A1 (en) | 2000-07-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| YU27304A (sh) | Novi dihidropteridinoni, postupak za njihovo dobijanje i njihova primena kao lekova | |
| BR0307432A (pt) | Difluormetiltiazolilcarboxanilidas | |
| MXPA04000622A (es) | Pirazolilcarboxanilidas como funguicidas. | |
| MX2007006549A (es) | Procedimiento para preparar derivados condensados de piperazin-2-ona, asi como productos intermedios del procedimiento. | |
| YU12000A (sh) | Supstituisani 1,2,3,4,5,6-heksahidro-2,6-metano-3-benzazocin -10-oli, postupak za njihovo pripremanje i njihova primena kao lekova | |
| DE60138271D1 (de) | Herstellung von DIBENZOÄB,FÜAZEPINE ZWISCHENPRODUKTE | |
| ATE234813T1 (de) | Ketonperoxidderivate, ihre herstellung und verwendung | |
| DE60023402D1 (de) | Herstellung von 3-amino-2-chlor-4-methylpyridin aus aceton und ethylcyanoacetat | |
| DE60235820D1 (de) | Verfahren zur herstellung von azoverbindungen | |
| DE60106057D1 (de) | Verfahren zur herstellung von baccatin iii-derivativen | |
| ATE264306T1 (de) | Synthese von 3-amino-2-chlor-4-methylpyridin aus malonsäuresäurenitril und aceton | |
| ATE244706T1 (de) | Enantiomere von mercaptolactonen und verfahren zu ihrer herstellung | |
| PL372933A1 (en) | Methylthiophene carboxanilides | |
| ZA983231B (en) | Substituted benzyloxyimino compounds. | |
| MXPA04004526A (es) | N-metil-homocisteinas, su uso y metodo para su produccion. | |
| YU67203A (sh) | Derivati caloporosida, postupak za njihovu proizvodnju i njihova primena | |
| ATE466847T1 (de) | Verfahren zur herstellung von 14-beta- hydroxybaccatin-iii-1,14-carbonat | |
| ATE537160T1 (de) | Verfahren zur herstellung von 14beta- hydroxybaccatin-iii-1,14-carbonat | |
| ATE265418T1 (de) | Neue substituierte 3-phenoxy- und 3- phenylalkyloxy-2-phenyl-propylamine | |
| NO20052329L (no) | Fremgangsmate for rensingen av 1,4-butandiol-mononitrat | |
| AU2003903132A0 (en) | Plant promoter | |
| MY119688A (en) | Use of arylguanidinium xanthogenates as vulcanization accelerators and process for the production thereof | |
| MXPA05009696A (es) | Procedimiento para producir 1-aril- y 1-heteroaril-2-aminoetanoles enantiomericamente enriquecidos. | |
| DE69818431D1 (de) | Verfahren zur herstellung von 3-cyanopyridin aus 2-methyl-1,5-pentandiamin | |
| NO20020328L (no) | Fremgangsmåte for fremstilling av 4-cyano-2-aminometyltiazol |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1070053 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |