ATE312940T1 - Chromogenischen enzymsubstraten und verfahren zum nachweis von beta-d-ribofuranosidase-wirksamkeit - Google Patents
Chromogenischen enzymsubstraten und verfahren zum nachweis von beta-d-ribofuranosidase-wirksamkeitInfo
- Publication number
- ATE312940T1 ATE312940T1 AT02772539T AT02772539T ATE312940T1 AT E312940 T1 ATE312940 T1 AT E312940T1 AT 02772539 T AT02772539 T AT 02772539T AT 02772539 T AT02772539 T AT 02772539T AT E312940 T1 ATE312940 T1 AT E312940T1
- Authority
- AT
- Austria
- Prior art keywords
- ribofuranosidase
- substrate
- effectiveness
- enzyme substrates
- detecting
- Prior art date
Links
- 239000000758 substrate Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 230000001580 bacterial effect Effects 0.000 abstract 2
- -1 catechol compound Chemical class 0.000 abstract 2
- 229920001817 Agar Polymers 0.000 abstract 1
- 241001135699 Arcanobacterium Species 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000186227 Corynebacterium diphtheriae Species 0.000 abstract 1
- PCKPVGOLPKLUHR-UHFFFAOYSA-N OH-Indolxyl Natural products C1=CC=C2C(O)=CNC2=C1 PCKPVGOLPKLUHR-UHFFFAOYSA-N 0.000 abstract 1
- 241000607768 Shigella Species 0.000 abstract 1
- 241000607598 Vibrio Species 0.000 abstract 1
- 241000607734 Yersinia <bacteria> Species 0.000 abstract 1
- 239000008272 agar Substances 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- YCIMNLLNPGFGHC-UHFFFAOYSA-N o-dihydroxy-benzene Natural products OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/07—Benzo[b]pyran-4-ones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0125528A GB0125528D0 (en) | 2001-10-24 | 2001-10-24 | Enzyme substrates |
| GB0221716A GB0221716D0 (en) | 2002-09-18 | 2002-09-18 | Chromogenic enzyme substrates |
| PCT/GB2002/004800 WO2003035896A2 (en) | 2001-10-24 | 2002-10-24 | Chromogenic enzyme substrates and method for detecting beta-d-ribofuranosidase activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312940T1 true ATE312940T1 (de) | 2005-12-15 |
Family
ID=26246694
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02772539T ATE312940T1 (de) | 2001-10-24 | 2002-10-24 | Chromogenischen enzymsubstraten und verfahren zum nachweis von beta-d-ribofuranosidase-wirksamkeit |
| AT02770105T ATE316148T1 (de) | 2001-10-24 | 2002-10-24 | Enzymsubstrate zum nachweis der beta-d- ribofuranosidase aktivität |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02770105T ATE316148T1 (de) | 2001-10-24 | 2002-10-24 | Enzymsubstrate zum nachweis der beta-d- ribofuranosidase aktivität |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7323488B2 (de) |
| EP (2) | EP1438424B1 (de) |
| AT (2) | ATE312940T1 (de) |
| AU (2) | AU2002336205A1 (de) |
| DE (2) | DE60208809T2 (de) |
| ES (2) | ES2254745T3 (de) |
| WO (2) | WO2003035897A2 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7344854B2 (en) * | 1999-07-20 | 2008-03-18 | Micrology Laboratories, Llc | Test media for quantitative or qualitative identification and differentiation of general coliforms, E. coli, Aeromonas spp and Salmonella spp in a test sample |
| AU2002336205A1 (en) * | 2001-10-24 | 2003-05-06 | Michael Burton | Enzyme substrates for detecting beta-d-ribofuranosidase activity |
| US8785403B2 (en) | 2003-08-01 | 2014-07-22 | Mitsubishi Tanabe Pharma Corporation | Glucopyranoside compound |
| TW200526678A (en) | 2003-08-01 | 2005-08-16 | Janssen Pharmaceutica Nv | Substituted indole-O-glucosides |
| ES2531660T3 (es) | 2003-08-01 | 2015-03-18 | Mitsubishi Tanabe Pharma Corporation | Compuestos novedosos que tienen actividad inhibidora frente a transportador de glucosa dependiente de sodio |
| DE102005026500B4 (de) * | 2005-06-09 | 2008-05-15 | Philipps-Universität Marburg | Herstellung von N-Arylcarbamaten und N-Arylisocyanaten |
| UY30730A1 (es) * | 2006-12-04 | 2008-07-03 | Mitsubishi Tanabe Pharma Corp | Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno |
| RS56990B1 (sr) * | 2007-09-10 | 2018-05-31 | Janssen Pharmaceutica Nv | Postupak za dobijanje jedinjenja koja su korisna kao inhibitori sglt |
| FR2924127B1 (fr) * | 2007-11-26 | 2013-02-08 | Biomerieux Sa | Milieu reactionnel pour la detection et/ou l'identification de staphyloccocus aureus |
| CL2008003653A1 (es) | 2008-01-17 | 2010-03-05 | Mitsubishi Tanabe Pharma Corp | Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica. |
| US9056850B2 (en) * | 2008-10-17 | 2015-06-16 | Janssen Pharmaceutica N.V. | Process for the preparation of compounds useful as inhibitors of SGLT |
| US20110009347A1 (en) | 2009-07-08 | 2011-01-13 | Yin Liang | Combination therapy for the treatment of diabetes |
| EP2451797B1 (de) | 2009-07-10 | 2013-04-03 | Janssen Pharmaceutica, N.V. | Kristallisationsverfahren für 1-(beta-d-glucopyranosyl)-4-methyl-3-[5-(4-fluorphenyl)-2-thienylmethyl]benzol |
| HUE031375T2 (en) * | 2009-10-14 | 2017-07-28 | Janssen Pharmaceutica Nv | Process for the preparation of compounds useful as inhibitors of sglt2 |
| SG10201506114UA (en) | 2010-05-11 | 2015-09-29 | Janssen Pharmaceutica Nv | Pharmaceutical formulations comprising 1 - (beta-d-glucopyranosyl) - 2 -thienylmethylbenzene derivatives as inhibitors of sglt |
| EP2697218B1 (de) | 2011-04-13 | 2016-05-25 | Janssen Pharmaceutica NV | Verfahren zur herstellung von verbindungen die als sglt2 inhibitoren verwendbar sind |
| TWI542596B (zh) | 2011-05-09 | 2016-07-21 | 健生藥品公司 | （２ｓ,３ｒ,４ｒ,５ｓ,６ｒ）－２－（３－（（５－（４－氟苯基）噻吩－２－基）甲基）－４－甲基苯基）－６－（羥甲基）四氫－２ｈ－哌喃－３,４,５－三醇之ｌ－脯胺酸及檸檬酸共晶體 |
| CN103333817B (zh) * | 2013-06-05 | 2015-07-01 | 南昌大学 | 磁分离小肠结肠炎耶尔森氏菌ye的方法 |
| GB201319768D0 (en) | 2013-11-08 | 2013-12-25 | Glycosynth Ltd | Naphthalene derived chromogenic enzyme substrates |
| US20170071970A1 (en) | 2015-09-15 | 2017-03-16 | Janssen Pharmaceutica Nv | Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders |
| CN111393352A (zh) * | 2020-04-21 | 2020-07-10 | 中国科学院化学研究所 | 5-溴-6-氯-3-羟基吲哚-2-甲酸甲酯化合物及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364767A (en) * | 1993-02-11 | 1994-11-15 | Research Organics, In. | Chromogenic compounds and methods of using same |
| JPH093090A (ja) * | 1995-06-21 | 1997-01-07 | Sankyo Co Ltd | 新規化合物ａ−７６２０２ｍ及びその製法 |
| AU1739097A (en) * | 1996-02-23 | 1997-09-10 | Albert Einstein College Of Medicine Of Yeshiva University | Enzyme detection/assay method and substrates |
| FR2770538B1 (fr) | 1997-11-06 | 2000-10-13 | Bio Merieux | Procede et agent de detection et d'identification et/ou quantification d'une activite enzymatique de type desaminase |
| JP2000186098A (ja) * | 1998-12-22 | 2000-07-04 | Sankyo Co Ltd | Ａ−７６２０２及びその類縁化合物の製造方法 |
| US6350588B1 (en) * | 1999-07-20 | 2002-02-26 | Micrology Laboratories, Llc | Test media and quantitative or qualitative method for identification and differentiation of biological materials in a test sample |
| GB0125532D0 (en) * | 2001-10-24 | 2001-12-12 | Burton Michael | Enzyme activity indicators |
| AU2002336205A1 (en) * | 2001-10-24 | 2003-05-06 | Michael Burton | Enzyme substrates for detecting beta-d-ribofuranosidase activity |
-
2002
- 2002-10-24 AU AU2002336205A patent/AU2002336205A1/en not_active Abandoned
- 2002-10-24 DE DE60208809T patent/DE60208809T2/de not_active Expired - Lifetime
- 2002-10-24 ES ES02772539T patent/ES2254745T3/es not_active Expired - Lifetime
- 2002-10-24 AT AT02772539T patent/ATE312940T1/de not_active IP Right Cessation
- 2002-10-24 ES ES02770105T patent/ES2256535T3/es not_active Expired - Lifetime
- 2002-10-24 US US10/493,483 patent/US7323488B2/en not_active Expired - Lifetime
- 2002-10-24 DE DE60208063T patent/DE60208063T2/de not_active Expired - Lifetime
- 2002-10-24 AT AT02770105T patent/ATE316148T1/de not_active IP Right Cessation
- 2002-10-24 EP EP02770105A patent/EP1438424B1/de not_active Expired - Lifetime
- 2002-10-24 EP EP02772539A patent/EP1436411B1/de not_active Expired - Lifetime
- 2002-10-24 AU AU2002337302A patent/AU2002337302A1/en not_active Abandoned
- 2002-10-24 WO PCT/GB2002/004815 patent/WO2003035897A2/en not_active Ceased
- 2002-10-24 WO PCT/GB2002/004800 patent/WO2003035896A2/en not_active Ceased
- 2002-10-24 US US10/493,472 patent/US7384763B2/en not_active Expired - Lifetime
-
2008
- 2008-04-17 US US12/104,916 patent/US7709223B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20080193959A1 (en) | 2008-08-14 |
| EP1436411A2 (de) | 2004-07-14 |
| EP1438424A2 (de) | 2004-07-21 |
| DE60208063D1 (de) | 2006-01-19 |
| DE60208809D1 (de) | 2006-04-06 |
| AU2002336205A1 (en) | 2003-05-06 |
| US20040259181A1 (en) | 2004-12-23 |
| EP1438424B1 (de) | 2006-01-18 |
| ES2254745T3 (es) | 2006-06-16 |
| WO2003035897A2 (en) | 2003-05-01 |
| WO2003035896A2 (en) | 2003-05-01 |
| ES2256535T3 (es) | 2006-07-16 |
| DE60208063T2 (de) | 2006-08-17 |
| DE60208809T2 (de) | 2006-11-02 |
| WO2003035896A3 (en) | 2004-04-22 |
| US20050124556A1 (en) | 2005-06-09 |
| EP1436411B1 (de) | 2005-12-14 |
| US7384763B2 (en) | 2008-06-10 |
| ATE316148T1 (de) | 2006-02-15 |
| AU2002337302A1 (en) | 2003-05-06 |
| US7323488B2 (en) | 2008-01-29 |
| WO2003035897A3 (en) | 2004-04-22 |
| US7709223B2 (en) | 2010-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |