ATE314070T1 - Verwendung von pyridoindolonderivaten zur herstellung von antikrebsmitteln - Google Patents

Verwendung von pyridoindolonderivaten zur herstellung von antikrebsmitteln

Info

Publication number: ATE314070T1
Authority: AT; Austria
Prior art keywords: anticancer agents; producing anticancer; pyridoindolone derivatives; pyridoindolone; derivatives
Prior art date: 2001-04-27

Application number

AT02732841T

Other languages

English (en)

Inventor

Bernard Bourrie

Pierre Casellas

Jean-Marie Derocq

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-27

Filing date

2002-04-26

Publication date

2006-01-15

2002-04-26 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2006-01-15 Application granted granted Critical

2006-01-15 Publication of ATE314070T1 publication Critical patent/ATE314070T1/de

Links

239000002246 antineoplastic agent Substances 0.000 title 1
YNHGMRWHXVMPEN-UHFFFAOYSA-N pyrrolo[2,3-f]quinolin-2-one Chemical class C1=CC=C2C3=NC(=O)C=C3C=CC2=N1 YNHGMRWHXVMPEN-UHFFFAOYSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT02732841T 2001-04-27 2002-04-26 Verwendung von pyridoindolonderivaten zur herstellung von antikrebsmitteln ATE314070T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0105843A FR2823975B1 (fr)	2001-04-27	2001-04-27	Nouvelle utilisation de pyridoindolone
PCT/FR2002/001449 WO2002087574A2 (fr)	2001-04-27	2002-04-26	Utilisation de derives de pyridoindolone pour la preparation de medicaments anticancereux

Publications (1)

Publication Number	Publication Date
ATE314070T1 true ATE314070T1 (de)	2006-01-15

Family

ID=8862882

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT02735502T ATE338548T1 (de)	2001-04-27	2002-04-26	Pyridoindolonderivate und antikrebsmittel enthaltende pharmazeutische mischungen
AT02732841T ATE314070T1 (de)	2001-04-27	2002-04-26	Verwendung von pyridoindolonderivaten zur herstellung von antikrebsmitteln

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT02735502T ATE338548T1 (de)	2001-04-27	2002-04-26	Pyridoindolonderivate und antikrebsmittel enthaltende pharmazeutische mischungen

Country Status (33)

Country	Link
US (3)	US7524857B2 (de)
EP (2)	EP1385512B1 (de)
JP (2)	JP2004528343A (de)
KR (1)	KR100847413B1 (de)
CN (2)	CN1505511A (de)
AR (1)	AR034313A1 (de)
AT (2)	ATE338548T1 (de)
BG (2)	BG108260A (de)
BR (1)	BR0209138A (de)
CA (2)	CA2443012C (de)
CY (1)	CY1105813T1 (de)
CZ (2)	CZ295224B6 (de)
DE (2)	DE60208365T2 (de)
DK (2)	DK1385513T3 (de)
EA (1)	EA005930B1 (de)
EE (2)	EE200300465A (de)
ES (2)	ES2254683T3 (de)
FR (1)	FR2823975B1 (de)
HU (2)	HUP0400744A2 (de)
IL (4)	IL158312A0 (de)
IS (1)	IS2441B (de)
MX (1)	MXPA03009639A (de)
NO (2)	NO20034787L (de)
NZ (1)	NZ528671A (de)
PL (2)	PL366916A1 (de)
PT (2)	PT1385512E (de)
RS (2)	RS50790B (de)
RU (1)	RU2292888C9 (de)
SK (2)	SK13242003A3 (de)
TW (1)	TWI252104B (de)
UA (1)	UA74876C2 (de)
WO (2)	WO2002087574A2 (de)
ZA (1)	ZA200307785B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2823975B1 (fr) *	2001-04-27	2003-05-30	Sanofi Synthelabo	Nouvelle utilisation de pyridoindolone
US7456193B2 (en) *	2002-10-23	2008-11-25	Sanofi-Aventis	Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2846329B1 (fr)	2002-10-23	2004-12-03	Sanofi Synthelabo	Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
FR2869316B1 (fr) *	2004-04-21	2006-06-02	Sanofi Synthelabo	Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr)	2005-10-20	2008-06-27	Sanofi Aventis Sa	Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1268772A (en) *	1968-03-15	1972-03-29	Glaxo Lab Ltd	NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US4263304A (en) *	1978-06-05	1981-04-21	Sumitomo Chemical Company, Limited	7 H-indolo[2,3-c]isoquinolines
SU833971A1 (ru) *	1979-07-10	1981-05-30	Ленинградский Химико-Фармацевтическийинститут	Способ получени 3-фенил-2-оксо- - КАРбОлиНОВ
SU833972A1 (ru)	1979-10-26	1981-05-30	Институт Физико-Органической Химиии Углехимии Ah Украинской Ccp	Имидазо(4,5-с)пиридиний иодиды вКАчЕСТВЕ пРОМЕжуТОчНыХ пРОдуКТОВ дл СиНТЕзА фуНгицидОВ
FR2595701B1 (fr) *	1986-03-17	1988-07-01	Sanofi Sa	Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant
US5035252A (en) *	1990-12-14	1991-07-30	Mondre Steven J	Nicotine-containing dental floss
EP0581388A1 (de) *	1992-07-30	1994-02-02	Glaxo Group Limited	Pyridoindolone Methansulfonat als 5HT und 5HT3 Rezeptor Antagonisten
EP0755454B1 (de) *	1994-04-13	2008-02-13	The Rockefeller University	Aav-vermittelte überbringung von dna in zellen des nervensystems
DE19502753A1 (de) *	1995-01-23	1996-07-25	Schering Ag	Neue 9H-Pyrido[3,4-b]indol-Derivate
US6486177B2 (en) *	1995-12-04	2002-11-26	Celgene Corporation	Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
DE19624659A1 (de) *	1996-06-20	1998-01-08	Klinge Co Chem Pharm Fab	Neue Pyridylalken- und Pyridylalkinsäureamide
FR2765582B1 (fr) *	1997-07-03	1999-08-06	Synthelabo	Derives de 3-alkyl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one leur preparation et leur application en therapeutique
FR2765581B1 (fr) *	1997-07-03	1999-08-06	Synthelabo	Derives de 3-aryl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one, leur preparation et leur application en therapeutique
EP1068205A1 (de) *	1998-04-02	2001-01-17	Neurogen Corporation	Aminoalkylsubstituierte 5,6,7,8-tetrahydro-9h-pyrido[2,3-b]indol- und 5,6,7,8-tetrahydro-9h-pyrimidino[4,5-b]indolderivate: crf1-spezifische liganden
IT1313592B1 (it)	1999-08-03	2002-09-09	Novuspharma Spa	Derivati di 1h-pirido 3,4-b indol-1-one.
US20020156016A1 (en) *	2001-03-30	2002-10-24	Gerald Minuk	Control of cell growth by altering cell membrane potentials
FR2823975B1 (fr) *	2001-04-27	2003-05-30	Sanofi Synthelabo	Nouvelle utilisation de pyridoindolone
FR2846329B1 (fr)	2002-10-23	2004-12-03	Sanofi Synthelabo	Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
FR2846330B1 (fr)	2002-10-23	2004-12-03	Sanofi Synthelabo	Derives de pyridoindolone substitues en -3 par groupe heterocyclique, leur preparation et leur application en therapeutique
US6958347B2 (en)	2002-12-18	2005-10-25	Pfizer Inc.	Aminophenanthridinone and aminophenanthridine as NPY-5 antagonists
FR2869316B1 (fr)	2004-04-21	2006-06-02	Sanofi Synthelabo	Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr)	2005-10-20	2008-06-27	Sanofi Aventis Sa	Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

2001
- 2001-04-27 FR FR0105843A patent/FR2823975B1/fr not_active Expired - Fee Related
2002
- 2002-04-26 DE DE60208365T patent/DE60208365T2/de not_active Expired - Lifetime
- 2002-04-26 WO PCT/FR2002/001449 patent/WO2002087574A2/fr not_active Ceased
- 2002-04-26 SK SK1324-2003A patent/SK13242003A3/sk unknown
- 2002-04-26 WO PCT/FR2002/001450 patent/WO2002087575A1/fr not_active Ceased
- 2002-04-26 EA EA200301062A patent/EA005930B1/ru not_active IP Right Cessation
- 2002-04-26 US US10/476,321 patent/US7524857B2/en not_active Expired - Lifetime
- 2002-04-26 DE DE60214533T patent/DE60214533T2/de not_active Expired - Lifetime
- 2002-04-26 CZ CZ20032909A patent/CZ295224B6/cs not_active IP Right Cessation
- 2002-04-26 PL PL02366916A patent/PL366916A1/xx not_active IP Right Cessation
- 2002-04-26 NZ NZ528671A patent/NZ528671A/en unknown
- 2002-04-26 PT PT02732841T patent/PT1385512E/pt unknown
- 2002-04-26 CN CNA028089596A patent/CN1505511A/zh active Pending
- 2002-04-26 AT AT02735502T patent/ATE338548T1/de not_active IP Right Cessation
- 2002-04-26 ES ES02732841T patent/ES2254683T3/es not_active Expired - Lifetime
- 2002-04-26 EE EEP200300465A patent/EE200300465A/xx unknown
- 2002-04-26 IL IL15831202A patent/IL158312A0/xx unknown
- 2002-04-26 AT AT02732841T patent/ATE314070T1/de not_active IP Right Cessation
- 2002-04-26 JP JP2002584919A patent/JP2004528343A/ja active Pending
- 2002-04-26 US US10/476,322 patent/US6967203B2/en not_active Expired - Lifetime
- 2002-04-26 PL PL02366910A patent/PL366910A1/xx unknown
- 2002-04-26 CA CA002443012A patent/CA2443012C/fr not_active Expired - Fee Related
- 2002-04-26 AR ARP020101521A patent/AR034313A1/es unknown
- 2002-04-26 SK SK1325-2003A patent/SK13252003A3/sk unknown
- 2002-04-26 RU RU2003130376/15A patent/RU2292888C9/ru active
- 2002-04-26 KR KR1020037013925A patent/KR100847413B1/ko not_active Expired - Fee Related
- 2002-04-26 IL IL15826602A patent/IL158266A0/xx unknown
- 2002-04-26 EP EP02732841A patent/EP1385512B1/de not_active Expired - Lifetime
- 2002-04-26 TW TW091108716A patent/TWI252104B/zh not_active IP Right Cessation
- 2002-04-26 CN CNB028088980A patent/CN1240382C/zh not_active Expired - Fee Related
- 2002-04-26 ES ES02735502T patent/ES2271264T3/es not_active Expired - Lifetime
- 2002-04-26 RS YUP-834/03A patent/RS50790B/sr unknown
- 2002-04-26 JP JP2002584920A patent/JP2004531538A/ja active Pending
- 2002-04-26 DK DK02735502T patent/DK1385513T3/da active
- 2002-04-26 DK DK02732841T patent/DK1385512T3/da active
- 2002-04-26 HU HU0400744A patent/HUP0400744A2/hu unknown
- 2002-04-26 CZ CZ20032910A patent/CZ299465B6/cs not_active IP Right Cessation
- 2002-04-26 HU HU0400745A patent/HUP0400745A2/hu unknown
- 2002-04-26 EP EP02735502A patent/EP1385513B1/de not_active Expired - Lifetime
- 2002-04-26 MX MXPA03009639A patent/MXPA03009639A/es active IP Right Grant
- 2002-04-26 UA UA2003109248A patent/UA74876C2/uk unknown
- 2002-04-26 EE EEP200300466A patent/EE200300466A/xx unknown
- 2002-04-26 RS YUP-839/03A patent/RS50791B/sr unknown
- 2002-04-26 BR BR0209138-0A patent/BR0209138A/pt not_active IP Right Cessation
- 2002-04-26 CA CA002444334A patent/CA2444334A1/fr not_active Abandoned
- 2002-04-26 PT PT02735502T patent/PT1385513E/pt unknown
2003
- 2003-10-02 IL IL158266A patent/IL158266A/en not_active IP Right Cessation
- 2003-10-06 ZA ZA200307785A patent/ZA200307785B/en unknown
- 2003-10-08 IL IL158312A patent/IL158312A/en not_active IP Right Cessation
- 2003-10-09 IS IS6984A patent/IS2441B/is unknown
- 2003-10-13 BG BG108260A patent/BG108260A/bg unknown
- 2003-10-13 BG BG108261A patent/BG108261A/bg unknown
- 2003-10-24 NO NO20034787A patent/NO20034787L/no not_active Application Discontinuation
- 2003-10-24 NO NO20034785A patent/NO20034785L/no not_active Application Discontinuation
2005
- 2005-08-15 US US11/204,275 patent/US7160895B2/en not_active Expired - Lifetime
2006
- 2006-11-30 CY CY20061101725T patent/CY1105813T1/el unknown

Also Published As

Publication number	Publication date
PL366916A1 (en)	2005-02-07
IL158266A0 (en)	2004-05-12
CZ20032909A3 (en)	2004-06-16
MXPA03009639A (es)	2004-06-30
US7160895B2 (en)	2007-01-09
NO20034787L (no)	2003-12-23
IL158312A0 (en)	2004-05-12
DE60214533T2 (de)	2007-06-21
US20040122036A1 (en)	2004-06-24
CA2443012C (fr)	2009-07-28
YU83903A (sh)	2006-08-17
US20040122027A1 (en)	2004-06-24
CZ20032910A3 (en)	2004-07-14
JP2004531538A (ja)	2004-10-14
DE60214533D1 (de)	2006-10-19
JP2004528343A (ja)	2004-09-16
PT1385513E (pt)	2007-01-31
KR100847413B1 (ko)	2008-07-18
SK13242003A3 (sk)	2004-03-02
RS50791B (sr)	2010-08-31
BR0209138A (pt)	2004-06-08
EP1385512B1 (de)	2005-12-28
SK13252003A3 (sk)	2004-03-02
ES2271264T3 (es)	2007-04-16
EP1385512A2 (de)	2004-02-04
FR2823975B1 (fr)	2003-05-30
CN1505510A (zh)	2004-06-16
EE200300465A (et)	2003-12-15
CY1105813T1 (el)	2011-02-02
UA74876C2 (en)	2006-02-15
US7524857B2 (en)	2009-04-28
IL158266A (en)	2009-09-01
RU2003130376A (ru)	2005-04-10
PT1385512E (pt)	2006-05-31
CA2444334A1 (fr)	2002-11-07
NO20034785L (no)	2003-12-23
RU2292888C9 (ru)	2007-06-20
IS6984A (is)	2003-10-09
NZ528671A (en)	2004-06-25
US6967203B2 (en)	2005-11-22
ZA200307785B (en)	2004-10-06
YU83403A (sh)	2006-08-17
TWI252104B (en)	2006-04-01
WO2002087574A2 (fr)	2002-11-07
CA2443012A1 (en)	2002-11-07
DE60208365D1 (de)	2006-02-02
EA005930B1 (ru)	2005-08-25
DK1385512T3 (da)	2006-05-22
HK1059895A1 (en)	2004-07-23
EE200300466A (et)	2003-12-15
DK1385513T3 (da)	2007-01-15
FR2823975A1 (fr)	2002-10-31
US20050272760A1 (en)	2005-12-08
WO2002087574A3 (fr)	2003-02-13
ES2254683T3 (es)	2006-06-16
HUP0400745A2 (hu)	2004-08-30
IS2441B (is)	2008-11-15
PL366910A1 (en)	2005-02-07
KR20040015138A (ko)	2004-02-18
NO20034785D0 (no)	2003-10-24
HUP0400744A2 (hu)	2004-06-28
AR034313A1 (es)	2004-02-18
CZ299465B6 (cs)	2008-08-06
RU2292888C2 (ru)	2007-02-10
EP1385513A1 (de)	2004-02-04
CN1240382C (zh)	2006-02-08
ATE338548T1 (de)	2006-09-15
BG108261A (bg)	2004-12-30
DE60208365T2 (de)	2006-09-07
CZ295224B6 (cs)	2005-06-15
IL158312A (en)	2009-09-01
CN1505511A (zh)	2004-06-16
BG108260A (bg)	2004-12-30
EA200301062A1 (ru)	2004-04-29
NO20034787D0 (no)	2003-10-24
HK1060066A1 (en)	2004-07-30
EP1385513B1 (de)	2006-09-06
WO2002087575A1 (fr)	2002-11-07
RS50790B (sr)	2010-08-31

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2007-01-15

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