ATE314392T1 - Einzelketten-gonadotropin - Google Patents

Einzelketten-gonadotropin

Info

Publication number
ATE314392T1
ATE314392T1 AT97122148T AT97122148T ATE314392T1 AT E314392 T1 ATE314392 T1 AT E314392T1 AT 97122148 T AT97122148 T AT 97122148T AT 97122148 T AT97122148 T AT 97122148T AT E314392 T1 ATE314392 T1 AT E314392T1
Authority
AT
Austria
Prior art keywords
present
stimulating
activity
fertility
relates
Prior art date
Application number
AT97122148T
Other languages
English (en)
Inventor
William R Moyle
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Application granted granted Critical
Publication of ATE314392T1 publication Critical patent/ATE314392T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Control Of Eletrric Generators (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
AT97122148T 1994-02-18 1995-02-17 Einzelketten-gonadotropin ATE314392T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19938294A 1994-02-18 1994-02-18

Publications (1)

Publication Number Publication Date
ATE314392T1 true ATE314392T1 (de) 2006-01-15

Family

ID=22737277

Family Applications (2)

Application Number Title Priority Date Filing Date
AT95911043T ATE342061T1 (de) 1994-02-18 1995-02-17 Verwendung eines nicht-neutralisierenden antikörpers spezifisch für die beta-untereinheit von luteinisierendem hormon zur erhöhung der fertilität
AT97122148T ATE314392T1 (de) 1994-02-18 1995-02-17 Einzelketten-gonadotropin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT95911043T ATE342061T1 (de) 1994-02-18 1995-02-17 Verwendung eines nicht-neutralisierenden antikörpers spezifisch für die beta-untereinheit von luteinisierendem hormon zur erhöhung der fertilität

Country Status (11)

Country Link
US (2) US7001597B1 (de)
EP (3) EP0751782B1 (de)
JP (3) JPH09509418A (de)
AT (2) ATE342061T1 (de)
AU (1) AU695111B2 (de)
CA (1) CA2183564C (de)
DE (2) DE69535260T2 (de)
DK (1) DK0751782T3 (de)
ES (2) ES2251731T3 (de)
PT (1) PT751782E (de)
WO (1) WO1995022340A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925549A (en) * 1996-04-15 1999-07-20 The Board Of Trustees Of The Leland Stanford Junior University Soluble 7-transmembrane domain G-protein-coupled receptor compositions and methods
AU4964197A (en) * 1996-11-12 1998-06-03 Teikoku Hormone Mfg. Co., Ltd. Recombinant single-stranded equine chorionic gonadotropin
ZA987497B (en) * 1997-09-08 1999-02-23 Akzo Nobel Nv Expression of gonadotropins in dictyostelium
US6103501A (en) * 1997-11-17 2000-08-15 Washington University Single chain glycoprotein hormones comprising two β and one α subunits and recombinant production thereof
US6635256B1 (en) * 1998-10-19 2003-10-21 Washington University Glycoprotein hormone compositions comprising two β subunits and methods of use thereof
US5981249A (en) * 1998-02-05 1999-11-09 Spectral Diagnostics, Inc. Single-chain polypeptides comprising creatine kinase M and creatine kinase B
EP1115866A1 (de) * 1998-09-22 2001-07-18 University of Maryland at Baltimore Mutanten der cysteinknoten-wachstumsfaktoren familie
DE19910394A1 (de) * 1999-03-03 2000-09-07 Schering Ag Substanzen für die Fertilitätskontrolle
US6342411B1 (en) * 1999-09-03 2002-01-29 Motorola Inc. Electronic component and method for manufacture
KR20010077538A (ko) * 2000-02-03 2001-08-20 김강권 단일체인 융모성성선자극호르몬 및 그 제조방법
JP2001333772A (ja) 2000-04-25 2001-12-04 Washington Univ 可変性の活性を有する単鎖稔性ホルモン
AU2001255624A1 (en) * 2000-04-25 2001-11-07 Washington University Single-chain fertility hormones with variable lh activity
US6987172B2 (en) 2001-03-05 2006-01-17 Washington University In St. Louis Multifunctional single chain glycoprotein hormones comprising three or more β subunits
EP1518863B1 (de) * 2003-09-26 2010-12-15 Institut National De La Recherche Agronomique (Inra) Antikörper modulierende die biologische Aktivität von Pferd-Choriongonadotropin
CN112189137A (zh) * 2018-03-16 2021-01-05 奎斯特诊断投资有限公司 多重患者样品中的睾丸酮的质谱法测定
BR102019004147A2 (pt) 2019-02-28 2020-10-06 Ouro Fino Saude Animal Participacoes S.A. Gonadotrofina coriônica equina recombinante (recg) biologicamente ativa e processo para obtenção da mesma, composição veterinária e uso
DE102023213284A1 (de) 2023-12-22 2025-06-26 Robert Bosch Gesellschaft mit beschränkter Haftung Vorrichtung und Verfahren zur Analyse einer Hormon-Konzentration

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514505A (en) * 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
US5284778A (en) * 1985-08-12 1994-02-08 The Trustees Of Columbia University In The City Of New York Sensitive bioassay using monoclonal antibodies which bind to hormone-receptor complexes
US4973577A (en) * 1986-04-04 1990-11-27 The Salk Institute For Biological Studies FSH-releasing peptides
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
ATE243754T1 (de) * 1987-05-21 2003-07-15 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung
WO1991016922A1 (en) * 1990-05-08 1991-11-14 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered immunological characteristics, efficacy and/or receptor specificity
WO1992022568A1 (en) * 1991-06-18 1992-12-23 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
US5508261A (en) * 1991-06-18 1996-04-16 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
WO1994012520A1 (en) * 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
ES2210307T3 (es) * 1994-08-12 2004-07-01 Washington University Formas monocatenarias del cuarteto de hormonas glicoproteinicas.

Also Published As

Publication number Publication date
EP0839831A2 (de) 1998-05-06
EP1849802A2 (de) 2007-10-31
DE69534723D1 (de) 2006-02-02
JP2002060347A (ja) 2002-02-26
EP0839831B1 (de) 2005-12-28
US20070253955A1 (en) 2007-11-01
JPH11263799A (ja) 1999-09-28
JPH09509418A (ja) 1997-09-22
EP0751782A4 (de) 2000-09-27
DE69534723T2 (de) 2006-08-31
EP0751782B1 (de) 2006-10-11
EP0839831A3 (de) 1999-09-29
DE69535260T2 (de) 2007-08-09
US7001597B1 (en) 2006-02-21
PT751782E (pt) 2007-01-31
DK0751782T3 (da) 2007-01-29
CA2183564A1 (en) 1995-08-24
CA2183564C (en) 2010-07-13
WO1995022340A1 (en) 1995-08-24
ATE342061T1 (de) 2006-11-15
EP0751782A1 (de) 1997-01-08
AU1878795A (en) 1995-09-04
ES2251731T3 (es) 2006-05-01
AU695111B2 (en) 1998-08-06
ES2273335T3 (es) 2007-05-01
DE69535260D1 (de) 2006-11-23

Similar Documents

Publication Publication Date Title
ATE314392T1 (de) Einzelketten-gonadotropin
US4780451B1 (en) Composition and method for producing superovulation in cattle
ES2009948A6 (es) Procedimiento de preparacion de una proteina procedente de una hormona estimulante folicular urinaria, mediante proceso de inmunopurificacion de un concentrado urinario post-menopausico.
EP0607297A4 (en) Hormone analogs with multiple ctp extensions.
SI1887016T1 (sl) Fragmenti človeškega horijevega gonadotropina (hcg) kot imunoregulator
DE3884776D1 (de) Durch "site-directed" Mutagenese modifzierte Glukoprotein-Hormone und Verfahren zu deren Verwendung.
KR910016340A (ko) 안정화된 고나도트로핀을 함유하는 제제
Zhang et al. Macrophages in human reproductive tissues contain luteinizing hormone/chorionic gonadotropin receptors
ATE115409T1 (de) Glykoprotein-hormonrezeptor-moleküle.
DE602004030546D1 (de) LH zur Verwendung der Erhaltung einer oder mehreren Schwangerschaften durch Induktion der Bildung des sekundären Gelbkörpers.
RU2006136919A (ru) Суперагонисты фолликулостимулирующего гормона
Xing et al. Efficient preparation of glycoprotein hormones lacking an α-subunit oligosaccharide
KR900702048A (ko) 고나도트로핀 및 그에 의한 과할성 작용제의 제조 방법
PL1518863T3 (pl) Przeciwciała modulujące aktywność końskiej gonadotropiny kosmówkowej
JPS63503141A (ja) 動物の生殖機能の調節方法
DE4000327A1 (de) Arzneimittel zur verbesserung der ovarreaktion und der eizell- und embryonen- produktion bei haussaeugetieren
Quesnel et al. Solubilization and purification of the gonadotropin (GTH II) receptor from rainbow trout (Oncorhynchus mykiss) ovaries
CA2219948A1 (en) Single chain gonadotropins, dna encoding them and method of producing
Matteri et al. Biochemical and biological properties of urinary follicle‐stimulating hormone (FSH) from the rhesus monkey (Macaca mulatta)
Magistretti et al. Comparison of the effects of hGRF, VIP and PHI on cAMP and glycogen levels in mouse cerebral cortical slices and on growth hormone (GH) release from perfused rat anterior pituitary cells
Andrade et al. Effects of body condition and GnRH pulse infusion on LH profiles, ovarian follicle populations and ovulation in postpartum beef cows
Muralidhar Indigenous Production of Bovine/Bubaline Reproductive Hormones
BR0101322A (pt) Processo de obtenção, composição e uso de um sistema de hormÈnios recombinantes para superovulação em vertebrados e invertebrados

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0839831

Country of ref document: EP