DE69534723D1 - Einzelketten-Gonadotropin - Google Patents

Einzelketten-Gonadotropin

Info

Publication number
DE69534723D1
DE69534723D1 DE69534723T DE69534723T DE69534723D1 DE 69534723 D1 DE69534723 D1 DE 69534723D1 DE 69534723 T DE69534723 T DE 69534723T DE 69534723 T DE69534723 T DE 69534723T DE 69534723 D1 DE69534723 D1 DE 69534723D1
Authority
DE
Germany
Prior art keywords
present
stimulating
activity
fertility
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69534723T
Other languages
English (en)
Other versions
DE69534723T2 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St Louis University
Washington University in St Louis WUSTL
Original Assignee
St Louis University
Washington University in St Louis WUSTL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Louis University, Washington University in St Louis WUSTL filed Critical St Louis University
Publication of DE69534723D1 publication Critical patent/DE69534723D1/de
Application granted granted Critical
Publication of DE69534723T2 publication Critical patent/DE69534723T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Control Of Eletrric Generators (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69534723T 1994-02-18 1995-02-17 Einzelketten-Gonadotropin Expired - Lifetime DE69534723T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19938294A 1994-02-18 1994-02-18
US199382 1994-02-18

Publications (2)

Publication Number Publication Date
DE69534723D1 true DE69534723D1 (de) 2006-02-02
DE69534723T2 DE69534723T2 (de) 2006-08-31

Family

ID=22737277

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69535260T Expired - Lifetime DE69535260T2 (de) 1994-02-18 1995-02-17 Verwendung eines nicht-neutralisierenden Antikörpers spezifisch für die beta-Untereinheit von luteinisierendem Hormon zur Erhöhung der Fertilität
DE69534723T Expired - Lifetime DE69534723T2 (de) 1994-02-18 1995-02-17 Einzelketten-Gonadotropin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69535260T Expired - Lifetime DE69535260T2 (de) 1994-02-18 1995-02-17 Verwendung eines nicht-neutralisierenden Antikörpers spezifisch für die beta-Untereinheit von luteinisierendem Hormon zur Erhöhung der Fertilität

Country Status (11)

Country Link
US (2) US7001597B1 (de)
EP (3) EP0751782B1 (de)
JP (3) JPH09509418A (de)
AT (2) ATE342061T1 (de)
AU (1) AU695111B2 (de)
CA (1) CA2183564C (de)
DE (2) DE69535260T2 (de)
DK (1) DK0751782T3 (de)
ES (2) ES2251731T3 (de)
PT (1) PT751782E (de)
WO (1) WO1995022340A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925549A (en) * 1996-04-15 1999-07-20 The Board Of Trustees Of The Leland Stanford Junior University Soluble 7-transmembrane domain G-protein-coupled receptor compositions and methods
AU4964197A (en) * 1996-11-12 1998-06-03 Teikoku Hormone Mfg. Co., Ltd. Recombinant single-stranded equine chorionic gonadotropin
ZA987497B (en) * 1997-09-08 1999-02-23 Akzo Nobel Nv Expression of gonadotropins in dictyostelium
US6103501A (en) * 1997-11-17 2000-08-15 Washington University Single chain glycoprotein hormones comprising two β and one α subunits and recombinant production thereof
US6635256B1 (en) * 1998-10-19 2003-10-21 Washington University Glycoprotein hormone compositions comprising two β subunits and methods of use thereof
US5981249A (en) * 1998-02-05 1999-11-09 Spectral Diagnostics, Inc. Single-chain polypeptides comprising creatine kinase M and creatine kinase B
EP1115866A1 (de) * 1998-09-22 2001-07-18 University of Maryland at Baltimore Mutanten der cysteinknoten-wachstumsfaktoren familie
DE19910394A1 (de) * 1999-03-03 2000-09-07 Schering Ag Substanzen für die Fertilitätskontrolle
US6342411B1 (en) * 1999-09-03 2002-01-29 Motorola Inc. Electronic component and method for manufacture
KR20010077538A (ko) * 2000-02-03 2001-08-20 김강권 단일체인 융모성성선자극호르몬 및 그 제조방법
JP2001333772A (ja) 2000-04-25 2001-12-04 Washington Univ 可変性の活性を有する単鎖稔性ホルモン
AU2001255624A1 (en) * 2000-04-25 2001-11-07 Washington University Single-chain fertility hormones with variable lh activity
US6987172B2 (en) 2001-03-05 2006-01-17 Washington University In St. Louis Multifunctional single chain glycoprotein hormones comprising three or more β subunits
EP1518863B1 (de) * 2003-09-26 2010-12-15 Institut National De La Recherche Agronomique (Inra) Antikörper modulierende die biologische Aktivität von Pferd-Choriongonadotropin
CN112189137A (zh) * 2018-03-16 2021-01-05 奎斯特诊断投资有限公司 多重患者样品中的睾丸酮的质谱法测定
BR102019004147A2 (pt) 2019-02-28 2020-10-06 Ouro Fino Saude Animal Participacoes S.A. Gonadotrofina coriônica equina recombinante (recg) biologicamente ativa e processo para obtenção da mesma, composição veterinária e uso
DE102023213284A1 (de) 2023-12-22 2025-06-26 Robert Bosch Gesellschaft mit beschränkter Haftung Vorrichtung und Verfahren zur Analyse einer Hormon-Konzentration

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514505A (en) * 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
US5284778A (en) * 1985-08-12 1994-02-08 The Trustees Of Columbia University In The City Of New York Sensitive bioassay using monoclonal antibodies which bind to hormone-receptor complexes
US4973577A (en) * 1986-04-04 1990-11-27 The Salk Institute For Biological Studies FSH-releasing peptides
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
ATE243754T1 (de) * 1987-05-21 2003-07-15 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung
WO1991016922A1 (en) * 1990-05-08 1991-11-14 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered immunological characteristics, efficacy and/or receptor specificity
WO1992022568A1 (en) * 1991-06-18 1992-12-23 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
US5508261A (en) * 1991-06-18 1996-04-16 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
WO1994012520A1 (en) * 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
ES2210307T3 (es) * 1994-08-12 2004-07-01 Washington University Formas monocatenarias del cuarteto de hormonas glicoproteinicas.

Also Published As

Publication number Publication date
EP0839831A2 (de) 1998-05-06
EP1849802A2 (de) 2007-10-31
JP2002060347A (ja) 2002-02-26
EP0839831B1 (de) 2005-12-28
US20070253955A1 (en) 2007-11-01
JPH11263799A (ja) 1999-09-28
JPH09509418A (ja) 1997-09-22
EP0751782A4 (de) 2000-09-27
DE69534723T2 (de) 2006-08-31
ATE314392T1 (de) 2006-01-15
EP0751782B1 (de) 2006-10-11
EP0839831A3 (de) 1999-09-29
DE69535260T2 (de) 2007-08-09
US7001597B1 (en) 2006-02-21
PT751782E (pt) 2007-01-31
DK0751782T3 (da) 2007-01-29
CA2183564A1 (en) 1995-08-24
CA2183564C (en) 2010-07-13
WO1995022340A1 (en) 1995-08-24
ATE342061T1 (de) 2006-11-15
EP0751782A1 (de) 1997-01-08
AU1878795A (en) 1995-09-04
ES2251731T3 (es) 2006-05-01
AU695111B2 (en) 1998-08-06
ES2273335T3 (es) 2007-05-01
DE69535260D1 (de) 2006-11-23

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Legal Events

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