ATE328109T1 - Test mit hohem durchsatz zur identifizierung von modifikatoren der genexpression - Google Patents
Test mit hohem durchsatz zur identifizierung von modifikatoren der genexpressionInfo
- Publication number
- ATE328109T1 ATE328109T1 AT02734208T AT02734208T ATE328109T1 AT E328109 T1 ATE328109 T1 AT E328109T1 AT 02734208 T AT02734208 T AT 02734208T AT 02734208 T AT02734208 T AT 02734208T AT E328109 T1 ATE328109 T1 AT E328109T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- gene
- compounds
- gene expression
- pools
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 2
- 239000003607 modifier Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 238000012413 Fluorescence activated cell sorting analysis Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1051—Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28899401P | 2001-05-04 | 2001-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE328109T1 true ATE328109T1 (de) | 2006-06-15 |
Family
ID=23109544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02734208T ATE328109T1 (de) | 2001-05-04 | 2002-05-06 | Test mit hohem durchsatz zur identifizierung von modifikatoren der genexpression |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7083919B2 (de) |
| EP (1) | EP1392847B1 (de) |
| JP (1) | JP2004533245A (de) |
| AT (1) | ATE328109T1 (de) |
| AU (1) | AU2002305391A1 (de) |
| CA (1) | CA2446207A1 (de) |
| DE (1) | DE60211895T2 (de) |
| WO (1) | WO2002090498A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE554185T1 (de) * | 2003-02-27 | 2012-05-15 | Alnylam Pharmaceuticals Inc | Verfahren und konstrukte zur bewertung von rnai- zielen und effektormolekülen |
| WO2009061837A1 (en) * | 2007-11-05 | 2009-05-14 | Novostem Therapeutics Inc | Neoplastic stem cell system and method |
| DE102010023486A1 (de) * | 2010-06-11 | 2011-12-15 | B. Braun Avitum Ag | Nachweisvorrichtung und -verfahren |
| JP6349327B2 (ja) | 2012-12-17 | 2018-06-27 | レウコドゥックス，リミテッド | 化学的状態を判定するためのシステムおよび方法 |
| US10610861B2 (en) * | 2012-12-17 | 2020-04-07 | Accellix Ltd. | Systems, compositions and methods for detecting a biological condition |
| US20240125701A1 (en) * | 2021-01-22 | 2024-04-18 | Toho University | Autofluorescence quenching device |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5922601A (en) | 1995-01-19 | 1999-07-13 | Biotransplant, Inc. | High efficiency gene trap selection of regulated genetic loci |
| US5695937A (en) | 1995-09-12 | 1997-12-09 | The Johns Hopkins University School Of Medicine | Method for serial analysis of gene expression |
| US5866330A (en) | 1995-09-12 | 1999-02-02 | The Johns Hopkins University School Of Medicine | Method for serial analysis of gene expression |
| US6020192A (en) * | 1996-01-18 | 2000-02-01 | University Of Florida | Humanized green fluorescent protein genes and methods |
| EP0818534A1 (de) * | 1996-07-12 | 1998-01-14 | Janssen Pharmaceutica N.V. | Menschliche Interleukine-12 Genexpressions-regulierende Sequenzen |
| US5928888A (en) | 1996-09-26 | 1999-07-27 | Aurora Biosciences Corporation | Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and secondary screening capabilities |
| US6207371B1 (en) | 1996-10-04 | 2001-03-27 | Lexicon Genetics Incorporated | Indexed library of cells containing genomic modifications and methods of making and utilizing the same |
| DE19650714A1 (de) | 1996-12-06 | 1998-06-10 | Melchner Harald Von Prof Dr | Genfallen-Konstrukt zur Identifizierung und Isolierung von Genen |
| US6214563B1 (en) * | 1997-08-01 | 2001-04-10 | Aurora Biosciences Corporation | Photon reducing agents for reducing undesired light emission in assays |
| CA2224475A1 (en) * | 1998-02-25 | 1999-08-25 | University Of British Columbia | Protein interaction and transcription factor trap |
| US6436707B1 (en) | 1998-03-27 | 2002-08-20 | Lexicon Genetics Incorporated | Vectors for gene mutagenesis and gene discovery |
| US6080576A (en) | 1998-03-27 | 2000-06-27 | Lexicon Genetics Incorporated | Vectors for gene trapping and gene activation |
| US20030143597A1 (en) * | 2000-12-28 | 2003-07-31 | Finney Robert E. | Methods for making polynucleotide libraries, polynucleotide arrays, and cell libraries for high-throughput genomics analysis |
-
2002
- 2002-05-06 AT AT02734208T patent/ATE328109T1/de not_active IP Right Cessation
- 2002-05-06 EP EP02734208A patent/EP1392847B1/de not_active Expired - Lifetime
- 2002-05-06 WO PCT/US2002/014212 patent/WO2002090498A2/en not_active Ceased
- 2002-05-06 AU AU2002305391A patent/AU2002305391A1/en not_active Abandoned
- 2002-05-06 DE DE60211895T patent/DE60211895T2/de not_active Expired - Fee Related
- 2002-05-06 US US10/139,420 patent/US7083919B2/en not_active Expired - Lifetime
- 2002-05-06 JP JP2002587561A patent/JP2004533245A/ja active Pending
- 2002-05-06 CA CA002446207A patent/CA2446207A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60211895D1 (de) | 2006-07-06 |
| US20020164636A1 (en) | 2002-11-07 |
| WO2002090498A3 (en) | 2003-05-01 |
| DE60211895T2 (de) | 2007-05-24 |
| AU2002305391A1 (en) | 2002-11-18 |
| EP1392847A2 (de) | 2004-03-03 |
| EP1392847A4 (de) | 2004-06-09 |
| JP2004533245A (ja) | 2004-11-04 |
| CA2446207A1 (en) | 2002-11-14 |
| EP1392847B1 (de) | 2006-05-31 |
| US7083919B2 (en) | 2006-08-01 |
| WO2002090498A2 (en) | 2002-11-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE459652T1 (de) | Verfahren zur herstellung von antikörpern | |
| Hällfors et al. | Quantifying the need and potential of assisted migration | |
| DE60034059D1 (de) | Zielgerichtete verfahren des wirkstoff screenings unter verwendung von co-kultivierungs verfahren | |
| DE60039072D1 (de) | Verfahren zum screenen von mehrfach transformierteon von fluoreszenzproteinen | |
| DK1131471T3 (da) | Et system til cellebaseret screening | |
| ATE540128T1 (de) | Verfahren und materialien unter anwendung von signalsonden | |
| ATE401397T1 (de) | Gerichtete evolution von biomolekülen unter der verwendung von mikrostrukturen | |
| DE69131181D1 (de) | Verfahren zum nachweis und zur quantifikation von zell-subsätzen innerhalb von subpopulationen einer vermischten zellpopulation | |
| ATE412184T1 (de) | Verfahren zur analyse einer mehrzahl von proben verschiedenen ursprungs auf einen analyten | |
| ATE429511T1 (de) | Verfahren zur entwicklung von gensätzen zu diagnostischen und therapeutischen zwecken auf grundlage des expressions- und methylierungsstatus der gene | |
| EA200800787A1 (ru) | Устройство и способ для удаления целевых агентов из образца | |
| DE60332948D1 (de) | Strategien zur genexpressionsanalyse | |
| EP0938545A4 (de) | Neuartige Verfahren und Zusammensetzungen zur Entdeckung von neuen multimerischen Molekülen, basierend auf einer kombinatorsichen Bibliothek | |
| ATE409236T1 (de) | Derivatisierte nukleinsäuren und deren verwendung | |
| DE602006021223D1 (de) | Verfahren zur identifizierung von trpv2-modulatoren | |
| ATE328109T1 (de) | Test mit hohem durchsatz zur identifizierung von modifikatoren der genexpression | |
| WO2003099781A3 (en) | METHODS FOR THE IDENTIFICATION OF IKKα FUNCTION AND OTHER GENES USEFUL FOR TREATMENT OF INFLAMMATORY DISEASES | |
| DE60103428D1 (de) | Identifizierung von zellen während kinetischer versuchsreihen | |
| DK0700442T3 (da) | Udödeliggjorte humane cellelinier med indhold af exogene cytokrome P450 gener | |
| Merced et al. | Patterning of stomata in the moss Funaria: a simple way to space guard cells | |
| WO2004101764A3 (en) | Methods of modulating metastasis and skeletal related events resulting from metastases | |
| WO2006007479A3 (en) | Method for enumerating mammalian cell micronuclei via differential staining | |
| WO2003089901A3 (en) | Methods for preparing libraries of unique tags and related screening methods | |
| DE602004029255D1 (de) | Verfahren zum nachweis von aneuploidie unter verwendung eines multiplex-mikropartikelnachweises | |
| ATE483724T1 (de) | Verfahren zur erhöhung der ausbreitung von b- zellen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |