ATE335823T1 - Verfahren zur biologischen herstellung von 1,3- propandiol - Google Patents

Verfahren zur biologischen herstellung von 1,3- propandiol

Info

Publication number
ATE335823T1
ATE335823T1 AT00955772T AT00955772T ATE335823T1 AT E335823 T1 ATE335823 T1 AT E335823T1 AT 00955772 T AT00955772 T AT 00955772T AT 00955772 T AT00955772 T AT 00955772T AT E335823 T1 ATE335823 T1 AT E335823T1
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AT
Austria
Prior art keywords
propanediol
dehydratase
coli
present
improved process
Prior art date
Application number
AT00955772T
Other languages
English (en)
Inventor
Mark Emptage
Sharon Haynie
Lisa Laffend
Jeff Pucci
Greg Whited
Original Assignee
Du Pont
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Genencor Int filed Critical Du Pont
Application granted granted Critical
Publication of ATE335823T1 publication Critical patent/ATE335823T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00955772T 1999-08-18 2000-08-18 Verfahren zur biologischen herstellung von 1,3- propandiol ATE335823T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14953499P 1999-08-18 1999-08-18

Publications (1)

Publication Number Publication Date
ATE335823T1 true ATE335823T1 (de) 2006-09-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
AT00955772T ATE335823T1 (de) 1999-08-18 2000-08-18 Verfahren zur biologischen herstellung von 1,3- propandiol

Country Status (13)

Country Link
US (5) US6514733B1 (de)
EP (1) EP1204755B1 (de)
JP (1) JP4716634B2 (de)
KR (1) KR100785997B1 (de)
CN (2) CN1298852C (de)
AT (1) ATE335823T1 (de)
BR (2) BRPI0013315B8 (de)
CA (2) CA2380616C (de)
DE (1) DE60029971T2 (de)
DK (1) DK1204755T3 (de)
HK (1) HK1044963B (de)
PT (1) PT1204755E (de)
WO (1) WO2001012833A2 (de)

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CN110205277A (zh) * 2019-05-14 2019-09-06 河北科技师范学院 肠炎沙门菌glpK基因缺失的应用
CN116064352A (zh) * 2020-03-12 2023-05-05 中国科学院上海高等研究院 高产1,3-丙二醇的克雷伯氏工程菌构建方法及应用
CN114107145B (zh) * 2021-11-04 2024-05-07 清华大学 一种重组微生物及其在生产1,3-丙二醇中的应用
CN117050924B (zh) * 2022-05-06 2025-12-12 中国科学院天津工业生物技术研究所 生产1,3-丙二醇的重组密歇根克雷伯氏菌及其构建方法与应用
CN119744301A (zh) * 2022-11-30 2025-04-01 株式会社Lg化学 同时产生1,3-丙二醇和3-羟基丙酸的微生物及其用途
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