ATE342897T1 - Chinoloncarbonsäurederivate oder deren salze - Google Patents

Chinoloncarbonsäurederivate oder deren salze

Info

Publication number: ATE342897T1
Authority: AT; Austria
Prior art keywords: optionally substituted; alkoxy; amino; acid derivatives; substituted alkyl
Prior art date: 1998-04-06

Application number

AT99912111T

Other languages

English (en)

Inventor

Kazuya Hayashi

Tokunori Kito

Junichi Mitsuyama

Tetsumi Yamakawa

Hiroshi Kuroda

Hiroyo Kawafuchi

Original Assignee

Toyama Chemical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-06

Filing date

1999-04-06

Publication date

2006-11-15

1999-04-06 Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd

2006-11-15 Application granted granted Critical

2006-11-15 Publication of ATE342897T1 publication Critical patent/ATE342897T1/de

Links

239000002253 acid Substances 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
125000000547 substituted alkyl group Chemical group 0.000 abstract 3
125000004414 alkyl thio group Chemical group 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
XOQQVKDBGLYPGH-UHFFFAOYSA-N 2-oxo-1h-quinoline-3-carboxylic acid Chemical class C1=CC=C2NC(=O)C(C(=O)O)=CC2=C1 XOQQVKDBGLYPGH-UHFFFAOYSA-N 0.000 abstract 1
125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
241000186427 Cutibacterium acnes Species 0.000 abstract 1
241000192125 Firmicutes Species 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
229940055019 propionibacterium acne Drugs 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000005346 substituted cycloalkyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT99912111T 1998-04-06 1999-04-06 Chinoloncarbonsäurederivate oder deren salze ATE342897T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP11014698		1998-04-06
JP34021798		1998-11-30

Publications (1)

Publication Number	Publication Date
ATE342897T1 true ATE342897T1 (de)	2006-11-15

Family

ID=26449822

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99912111T ATE342897T1 (de)	1998-04-06	1999-04-06	Chinoloncarbonsäurederivate oder deren salze

Country Status (14)

Country	Link
US (1)	US6335447B1 (de)
EP (1)	EP1070713B1 (de)
JP (1)	JP3346766B2 (de)
KR (1)	KR100550078B1 (de)
CN (1)	CN1152029C (de)
AT (1)	ATE342897T1 (de)
BR (1)	BRPI9909456B8 (de)
CA (1)	CA2327328C (de)
CY (1)	CY1105845T1 (de)
DE (1)	DE69933660T2 (de)
DK (1)	DK1070713T3 (de)
ES (1)	ES2273479T3 (de)
PT (1)	PT1070713E (de)
WO (1)	WO1999051588A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4061194B2 (ja) *	2001-02-08	2008-03-12	富山化学工業株式会社	６−置換アルキルアミノ−３−ピリジルホウ酸誘導体またはその塩およびそれらの製造法
EP1698336A1 (de) *	2005-03-01	2006-09-06	Ferrer Internacional, S.A.	Antimykotischezusammensetzungen enthaltend Sertaconazol und entweder Hydrokortison oder einen antibakteriellen Wikrstoff
ES2553179T3 (es) *	2005-08-01	2015-12-04	Maruho Co., Ltd.	Preparación de una loción que contiene un derivado del ácido piridoncarboxílico
EP2177208A1 (de)	2008-10-17	2010-04-21	Ferrer Internacional, S.A.	Pharmazeutische topische Zusammensetzungen
EP2177209A1 (de)	2008-10-17	2010-04-21	Ferrer Internacional, S.A.	Intravenöse Lösungen und Verwendungen
EP2177214A1 (de)	2008-10-17	2010-04-21	Ferrer Internacional, S.A.	Feste orale Dosierungsformen und Verwendungen
TWI513688B (zh) *	2010-04-06	2015-12-21	Ferrer Int	１－環丙基－８－甲基－７－〔５－甲基－６－（甲胺基）－３－吡啶基〕－４－側氧基－１，４－二氫－３－喹啉羧酸鹽
AU2010350521B2 (en)	2010-04-06	2015-04-16	Ferrer Internacional S.A.	1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid salts
EP3034078A1 (de) *	2010-09-27	2016-06-22	Emergent Product Development Gaithersburg Inc.	Antimikrobielle 2-pyridon-zusammensetzungen
HRP20180483T1 (hr) *	2011-08-31	2018-05-04	Otsuka Pharmaceutical Co., Ltd.	Spoj kinolona
EP3257512A4 (de) *	2015-02-13	2018-07-25	Maruho Co., Ltd.	Externes präparat mit pyridoncarbonsäurederivat
US10570152B2 (en) *	2015-07-28	2020-02-25	Vyome Therapeutics Limited	Antibacterial therapeutics and prophylactics
JP7347915B2 (ja) *	2016-04-28	2023-09-20	マルホ株式会社	抗菌剤
EP3549586A1 (de)	2016-12-01	2019-10-09	Maruho Co., Ltd.	Medizinisches hautpräparat zur äusserlichen anwendung
CN107121506B (zh) *	2017-04-13	2019-06-07	杭州华东医药集团新药研究院有限公司	奥泽沙星杂质及其用途
CN108299480A (zh) *	2017-12-27	2018-07-20	山东百诺医药股份有限公司	一种奥泽沙星及其中间体的制备方法
WO2020065668A1 (en) *	2018-09-26	2020-04-02	Maithri Drugs Pvt Ltd	Crystalline form of ozenoxacin and processes for preparation thereof
CN111675692A (zh) *	2020-06-08	2020-09-18	浙江科技学院	一种奥泽沙星的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3441788A1 (de) *	1984-11-15	1986-05-15	Bayer Ag, 5090 Leverkusen	Alkyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US5075319A (en) *	1987-09-08	1991-12-24	Sterling Drug Inc.	Pyridinyl-quinolone compounds, their preparation and use
US4959363A (en)	1989-06-23	1990-09-25	Sterling Drug Inc.	Quinolonecarboxamide compounds, their preparation and use as antivirals.
JP3145487B2 (ja)	1992-06-12	2001-03-12	シスメックス株式会社	粒子分析装置
DE4301246A1 (de) *	1993-01-19	1994-07-21	Bayer Ag	Chinolon- und Naphthyridoncarbonsäurederivate
NZ296532A (en) *	1994-11-24	2000-02-28	F	Substituted 5-benzyl-2,4,-diaminopyrimidines
KR100276477B1 (ko) *	1996-02-09	2000-12-15	나카노 가쓰히코	퀴놀론카복실산유도체또는그의염

1999
- 1999-04-06 AT AT99912111T patent/ATE342897T1/de active
- 1999-04-06 CN CNB998059145A patent/CN1152029C/zh not_active Expired - Lifetime
- 1999-04-06 DE DE69933660T patent/DE69933660T2/de not_active Expired - Lifetime
- 1999-04-06 BR BRPI9909456-8B1 patent/BRPI9909456B8/pt not_active IP Right Cessation
- 1999-04-06 EP EP99912111A patent/EP1070713B1/de not_active Expired - Lifetime
- 1999-04-06 ES ES99912111T patent/ES2273479T3/es not_active Expired - Lifetime
- 1999-04-06 PT PT99912111T patent/PT1070713E/pt unknown
- 1999-04-06 JP JP2000542309A patent/JP3346766B2/ja not_active Expired - Lifetime
- 1999-04-06 US US09/647,763 patent/US6335447B1/en not_active Expired - Lifetime
- 1999-04-06 KR KR1020007011078A patent/KR100550078B1/ko not_active Expired - Lifetime
- 1999-04-06 WO PCT/JP1999/001799 patent/WO1999051588A1/ja not_active Ceased
- 1999-04-06 CA CA002327328A patent/CA2327328C/en not_active Expired - Lifetime
- 1999-04-06 DK DK99912111T patent/DK1070713T3/da active
2006
- 2006-12-12 CY CY20061101789T patent/CY1105845T1/el unknown

Also Published As

Publication number	Publication date
DK1070713T3 (da)	2006-12-27
BRPI9909456A (pt)	2001-10-02
CN1152029C (zh)	2004-06-02
EP1070713A1 (de)	2001-01-24
KR100550078B1 (ko)	2006-02-08
WO1999051588A1 (en)	1999-10-14
DE69933660D1 (de)	2006-11-30
JP3346766B2 (ja)	2002-11-18
CA2327328A1 (en)	1999-10-14
CN1299356A (zh)	2001-06-13
EP1070713A4 (de)	2004-09-01
BRPI9909456B1 (pt)	2013-10-29
DE69933660T2 (de)	2007-08-23
US6335447B1 (en)	2002-01-01
CA2327328C (en)	2007-11-13
CY1105845T1 (el)	2011-02-02
KR20010042463A (ko)	2001-05-25
ES2273479T3 (es)	2007-05-01
BRPI9909456B8 (pt)	2021-07-06
EP1070713B1 (de)	2006-10-18
HK1039484A1 (en)	2002-04-26
PT1070713E (pt)	2006-12-29

Legal Events

Date

Code

Title

Description

2007-06-15

UEP

Publication of translation of european patent specification

Ref document number: 1070713

Country of ref document: EP

Publication	Publication Date	Title
DE69933660D1 (de)	2006-11-30	Chinoloncarbonsäurederivate oder deren salze
ATE157368T1 (de)	1997-09-15	6-0-methylerythromycin a-derivat
ATE161257T1 (de)	1998-01-15	Azolylamin-derivat
NZ228893A (en)	1990-06-26	Substituted quinoline and naphthyridine derivatives and pharmaceutical compositions
NO20002169L (no)	2000-05-18	Nye pyridazinderivater og medikamenter inneholdende disse som effektive ingredienser
DK0707007T3 (da)	2002-03-18	Amino(thio)etherderivater som CNS-aktive midler
BR9708828A (pt)	1999-08-03	Composto e composição herbicida
IL124944A (en)	2003-06-24	Quinolonecarboxylic acid derivatives or their salts and pharmaceutical compositions containing them
DK0920421T3 (da)	2003-03-10	Isoxazolinderivater anvendelige som antimikrobielle midler
DK0712853T3 (da)	2001-04-17	Pyrazolderivat
DK1262477T3 (da)	2008-12-01	Antibakterielle midler, der er virksomme mod syrefaste bakterier og indeholder pyridoncarboxylsyrer som aktiv ingrediens
MXPA04002649A (es)	2004-06-07	Diamidas insecticidas.
PL326024A1 (en)	1998-08-17	Novel derivatives of cyclodepsipeptidic substance pf1022
ZA916268B (en)	1992-04-29	Tricyclic compound or salts thereof,method for producing the same and antimicrobial agent containing the same
PT1338596E (pt)	2006-05-31	Processos para a preparacao de agentes antibacterianos do tipo carbapenem
WO2002032856A3 (en)	2002-07-04	Insecticidal 1,8-naphthalenedicarboxamides
ID16655A (id)	1997-10-30	Turunan-turunan sikloalkilaminometilpirolidina
ATE331720T1 (de)	2006-07-15	Pyridobenzoxazinderivate
PT897919E (pt)	2004-11-30	Novos derivados do acido piridonacarboxilico ou seus sais e agentes anti-bacterianos contendo-os como ingrediente activo
EP1118327A4 (de)	2006-08-02	Vorbeugende und/oder therapeutische mittel zur behandlung der sinusitis.
TH39034A3 (th)	2000-06-28	สารประกอบเอสเทอร์
MX9802192A (es)	1998-09-30	Derivados novedosos del acido piridona carboxilico o sus sales, y agentes antibacterianos que contienen los mismos como sus componentes efectivos.
DE69611148D1 (de)	2001-01-11	Pyrrolo(4,3,2-de)chinolin-Derivat