ATE345277T1 - Injizierbare pharmazeutische suspension in einer phiole mit zwei kammern - Google Patents
Injizierbare pharmazeutische suspension in einer phiole mit zwei kammernInfo
- Publication number
- ATE345277T1 ATE345277T1 AT03793140T AT03793140T ATE345277T1 AT E345277 T1 ATE345277 T1 AT E345277T1 AT 03793140 T AT03793140 T AT 03793140T AT 03793140 T AT03793140 T AT 03793140T AT E345277 T1 ATE345277 T1 AT E345277T1
- Authority
- AT
- Austria
- Prior art keywords
- formulation
- gaseous medium
- chamber
- injectable pharmaceutical
- medium
- Prior art date
Links
- 239000007971 pharmaceutical suspension Substances 0.000 title 1
- 239000002609 medium Substances 0.000 abstract 5
- 238000009472 formulation Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 238000013019 agitation Methods 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 230000016615 flocculation Effects 0.000 abstract 1
- 238000005189 flocculation Methods 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000010525 oxidative degradation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000375 suspending agent Substances 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2093—Containers having several compartments for products to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/02—Internal fittings
- B65D25/04—Partitions
- B65D25/08—Partitions with provisions for removing or destroying, e.g. to facilitate mixing of contents
- B65D25/082—Partitions with provisions for removing or destroying, e.g. to facilitate mixing of contents the partition being in the form of a plug or the like which is removed by increasing or decreasing the pressure within the container
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/202—Separating means
- A61J1/2041—Separating means having removable plugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Mechanical Engineering (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40498802P | 2002-08-21 | 2002-08-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE345277T1 true ATE345277T1 (de) | 2006-12-15 |
Family
ID=31946796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03793140T ATE345277T1 (de) | 2002-08-21 | 2003-08-20 | Injizierbare pharmazeutische suspension in einer phiole mit zwei kammern |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7387623B2 (de) |
| EP (1) | EP1545994B1 (de) |
| JP (1) | JP4416653B2 (de) |
| AT (1) | ATE345277T1 (de) |
| AU (1) | AU2003265511A1 (de) |
| CA (1) | CA2494825C (de) |
| DE (1) | DE60309731T2 (de) |
| ES (1) | ES2273078T3 (de) |
| NO (1) | NO328187B1 (de) |
| WO (1) | WO2004018312A1 (de) |
Families Citing this family (84)
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| GB2414409B (en) * | 2004-05-28 | 2009-11-18 | Cilag Ag Int | Injection device |
| GB2414405B (en) * | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| GB2414400B (en) * | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| GB2414404B (en) | 2004-05-28 | 2009-06-03 | Cilag Ag Int | Injection device |
| GB2414406B (en) | 2004-05-28 | 2009-03-18 | Cilag Ag Int | Injection device |
| GB2414401B (en) | 2004-05-28 | 2009-06-17 | Cilag Ag Int | Injection device |
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| GB2424836B (en) * | 2005-04-06 | 2010-09-22 | Cilag Ag Int | Injection device (bayonet cap removal) |
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| GB2424838B (en) * | 2005-04-06 | 2011-02-23 | Cilag Ag Int | Injection device (adaptable drive) |
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| US20110098656A1 (en) * | 2005-09-27 | 2011-04-28 | Burnell Rosie L | Auto-injection device with needle protecting cap having outer and inner sleeves |
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| US3087638A (en) * | 1961-12-15 | 1963-04-30 | Abbott Lab | Closure assembly |
| US3464414A (en) | 1963-07-31 | 1969-09-02 | Upjohn Co | Mixing vial construction |
| US3457348A (en) | 1966-06-27 | 1969-07-22 | American Cyanamid Co | Stable syringeable suspensions of parenteral drugs in complex floc form |
| US4089432A (en) * | 1977-05-06 | 1978-05-16 | The Upjohn Company | Vial and closure |
| NO165013C (no) * | 1977-09-14 | 1990-12-12 | Pemberton Sintermatic | Fremgangsmaate og apparat til fremstilling av kjoett eller kjoettlignende produkter. |
| US4258845A (en) | 1979-11-20 | 1981-03-31 | The Upjohn Company | Activator closure for two-compartment vial |
| US4614267A (en) | 1983-02-28 | 1986-09-30 | Abbott Laboratories | Dual compartmented container |
| US4871354A (en) | 1986-07-24 | 1989-10-03 | The West Company | Wet-dry bag with lyphozation vial |
| US5336180A (en) | 1990-04-24 | 1994-08-09 | Science Incorporated | Closed drug delivery system |
| SE9201246D0 (sv) * | 1992-04-21 | 1992-04-21 | Kabi Pharmacia Ab | Injection cartridge arrangement |
| JPH05317383A (ja) | 1992-05-19 | 1993-12-03 | Nissho Corp | 薬剤容器との連通手段を備えた溶解液容器 |
| US5385546A (en) | 1992-06-24 | 1995-01-31 | Science Incorporated | Mixing and delivering system |
| US5335773A (en) | 1993-07-02 | 1994-08-09 | Habley Medical Technology Corporation | Multi-pharmaceutical storage, mixing and dispensing vial |
| US5462526A (en) * | 1993-09-15 | 1995-10-31 | Mcgaw, Inc. | Flexible, sterile container and method of making and using same |
| DE19847968A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen |
| EP1251742A4 (de) * | 1999-10-18 | 2004-10-06 | Dial Corp | Vorrichtung und verfahren zur herstellung von hüllenlosen würsten |
| US6495534B2 (en) | 2000-05-15 | 2002-12-17 | Pharmacia & Upjohn Spa | Stabilized aqueous suspensions for parenteral use |
| US20030165568A1 (en) | 2000-05-15 | 2003-09-04 | Giuseppe Colombo | Stabilized steroidal suspension |
| JP2004337318A (ja) * | 2003-05-14 | 2004-12-02 | Otsuka Pharmaceut Factory Inc | 医療用複室容器及びその製造方法 |
-
2003
- 2003-08-20 AU AU2003265511A patent/AU2003265511A1/en not_active Abandoned
- 2003-08-20 DE DE2003609731 patent/DE60309731T2/de not_active Expired - Lifetime
- 2003-08-20 EP EP03793140A patent/EP1545994B1/de not_active Expired - Lifetime
- 2003-08-20 CA CA 2494825 patent/CA2494825C/en not_active Expired - Fee Related
- 2003-08-20 WO PCT/US2003/026005 patent/WO2004018312A1/en not_active Ceased
- 2003-08-20 AT AT03793140T patent/ATE345277T1/de not_active IP Right Cessation
- 2003-08-20 US US10/644,516 patent/US7387623B2/en not_active Expired - Lifetime
- 2003-08-20 JP JP2004531095A patent/JP4416653B2/ja not_active Expired - Lifetime
- 2003-08-20 ES ES03793140T patent/ES2273078T3/es not_active Expired - Lifetime
-
2005
- 2005-03-16 NO NO20051372A patent/NO328187B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004018312A1 (en) | 2004-03-04 |
| EP1545994B1 (de) | 2006-11-15 |
| AU2003265511A1 (en) | 2004-03-11 |
| DE60309731D1 (de) | 2006-12-28 |
| US7387623B2 (en) | 2008-06-17 |
| JP2005536285A (ja) | 2005-12-02 |
| CA2494825C (en) | 2009-02-17 |
| NO20051372L (no) | 2005-03-16 |
| JP4416653B2 (ja) | 2010-02-17 |
| NO328187B1 (no) | 2009-12-28 |
| CA2494825A1 (en) | 2004-03-04 |
| ES2273078T3 (es) | 2007-05-01 |
| DE60309731T2 (de) | 2007-06-28 |
| EP1545994A1 (de) | 2005-06-29 |
| US20040039366A1 (en) | 2004-02-26 |
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Legal Events
| Date | Code | Title | Description |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |