ATE346096T1 - G-csf tpo fusionsproteine - Google Patents

G-csf tpo fusionsproteine

Info

Publication number
ATE346096T1
ATE346096T1 AT96912262T AT96912262T ATE346096T1 AT E346096 T1 ATE346096 T1 AT E346096T1 AT 96912262 T AT96912262 T AT 96912262T AT 96912262 T AT96912262 T AT 96912262T AT E346096 T1 ATE346096 T1 AT E346096T1
Authority
AT
Austria
Prior art keywords
polypeptide
activity
csf
fusion polypeptide
fusion proteins
Prior art date
Application number
AT96912262T
Other languages
English (en)
Inventor
Haruhiko Yokoi
Yukimasa Shiotsu
Noboru Konishi
Hideharu Anazawa
Tatsuya Tamaoki
Motoo Yamasaki
Yoko Terasaki
Kazuhisa Uchida
Kinya Yamashita
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE346096T1 publication Critical patent/ATE346096T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/524Thrombopoietin, i.e. C-MPL ligand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT96912262T 1995-04-26 1996-04-26 G-csf tpo fusionsproteine ATE346096T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10262595 1995-04-26

Publications (1)

Publication Number Publication Date
ATE346096T1 true ATE346096T1 (de) 2006-12-15

Family

ID=14332430

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96912262T ATE346096T1 (de) 1995-04-26 1996-04-26 G-csf tpo fusionsproteine

Country Status (8)

Country Link
EP (1) EP0783003B1 (de)
JP (1) JP3763846B2 (de)
AT (1) ATE346096T1 (de)
AU (1) AU705064B2 (de)
CA (1) CA2194070A1 (de)
DE (1) DE69636714T2 (de)
ES (1) ES2276401T3 (de)
WO (1) WO1996034016A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869451A (en) * 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6251864B1 (en) 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6066318A (en) * 1995-10-05 2000-05-23 G.D. Searle & Co. Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors
US7091311B2 (en) 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
AU2002212108A1 (en) * 2000-11-02 2002-05-15 Maxygen Aps Single-chain multimeric polypeptides
MXPA05003057A (es) 2002-09-18 2006-04-18 Johnson & Johnson Metodos para aumentar la produccion de celulas madre hematopoyeticas y plaquetas.
US20050079155A1 (en) * 2003-03-20 2005-04-14 Xencor, Inc. Generating protein pro-drugs using reversible PPG linkages
US7723295B2 (en) 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
KR20120078742A (ko) 2003-08-28 2012-07-10 오르토-맥네일 파마슈티칼, 인코퍼레이티드 수용체에 결합하는 펩티드 및 화합물
WO2006041088A1 (ja) * 2004-10-12 2006-04-20 Tissue Targeting Japan Inc. 脳移行性骨髄前駆細胞
RU2385875C2 (ru) * 2008-04-24 2010-04-10 Ибмед Холдингс Лимитед Пептид, обладающий ростостимулирующей активностью гранулоцитарного колониестимулирующего фактора человека

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0796558B2 (ja) * 1988-03-31 1995-10-18 協和醗酵工業株式会社 修飾ポリペプチド
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
JPH04103599A (ja) * 1990-08-22 1992-04-06 Toray Ind Inc 融合ポリペプチド
CA2089553C (en) * 1990-08-29 2000-06-27 Paul Schendel Multidomain hematopoiesis stimulators
JPH05502463A (ja) * 1990-09-28 1993-04-28 オーソ・フアーマシユーチカル・コーポレーシヨン ハイブリツド成長因子

Also Published As

Publication number Publication date
CA2194070A1 (en) 1996-10-31
WO1996034016A1 (en) 1996-10-31
EP0783003A1 (de) 1997-07-09
ES2276401T3 (es) 2007-06-16
EP0783003A4 (de) 1998-01-07
AU5514796A (en) 1996-11-18
DE69636714T2 (de) 2007-10-18
EP0783003B1 (de) 2006-11-22
DE69636714D1 (de) 2007-01-04
JP3763846B2 (ja) 2006-04-05
AU705064B2 (en) 1999-05-13

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Legal Events

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