ATE346096T1 - G-csf tpo fusionsproteine - Google Patents
G-csf tpo fusionsproteineInfo
- Publication number
- ATE346096T1 ATE346096T1 AT96912262T AT96912262T ATE346096T1 AT E346096 T1 ATE346096 T1 AT E346096T1 AT 96912262 T AT96912262 T AT 96912262T AT 96912262 T AT96912262 T AT 96912262T AT E346096 T1 ATE346096 T1 AT E346096T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptide
- activity
- csf
- fusion polypeptide
- fusion proteins
- Prior art date
Links
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 title abstract 4
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 title abstract 4
- 102000037865 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 13
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 13
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 13
- 230000004927 fusion Effects 0.000 abstract 6
- 101800001707 Spacer peptide Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
- 150000002334 glycols Chemical class 0.000 abstract 1
- 229920001515 polyalkylene glycol Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10262595 | 1995-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE346096T1 true ATE346096T1 (de) | 2006-12-15 |
Family
ID=14332430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96912262T ATE346096T1 (de) | 1995-04-26 | 1996-04-26 | G-csf tpo fusionsproteine |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0783003B1 (de) |
| JP (1) | JP3763846B2 (de) |
| AT (1) | ATE346096T1 (de) |
| AU (1) | AU705064B2 (de) |
| CA (1) | CA2194070A1 (de) |
| DE (1) | DE69636714T2 (de) |
| ES (1) | ES2276401T3 (de) |
| WO (1) | WO1996034016A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869451A (en) * | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| US6251864B1 (en) | 1995-06-07 | 2001-06-26 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| US6066318A (en) * | 1995-10-05 | 2000-05-23 | G.D. Searle & Co. | Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors |
| US7091311B2 (en) | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
| AU2002212108A1 (en) * | 2000-11-02 | 2002-05-15 | Maxygen Aps | Single-chain multimeric polypeptides |
| MXPA05003057A (es) | 2002-09-18 | 2006-04-18 | Johnson & Johnson | Metodos para aumentar la produccion de celulas madre hematopoyeticas y plaquetas. |
| US20050079155A1 (en) * | 2003-03-20 | 2005-04-14 | Xencor, Inc. | Generating protein pro-drugs using reversible PPG linkages |
| US7723295B2 (en) | 2003-08-28 | 2010-05-25 | Ortho-Mcneil Pharmaceutical, Inc. | Peptides and compounds that bind to a receptor |
| KR20120078742A (ko) | 2003-08-28 | 2012-07-10 | 오르토-맥네일 파마슈티칼, 인코퍼레이티드 | 수용체에 결합하는 펩티드 및 화합물 |
| WO2006041088A1 (ja) * | 2004-10-12 | 2006-04-20 | Tissue Targeting Japan Inc. | 脳移行性骨髄前駆細胞 |
| RU2385875C2 (ru) * | 2008-04-24 | 2010-04-10 | Ибмед Холдингс Лимитед | Пептид, обладающий ростостимулирующей активностью гранулоцитарного колониестимулирующего фактора человека |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0796558B2 (ja) * | 1988-03-31 | 1995-10-18 | 協和醗酵工業株式会社 | 修飾ポリペプチド |
| AU5355790A (en) * | 1989-04-19 | 1990-11-16 | Cetus Corporation | Multifunctional m-csf proteins and genes encoding therefor |
| JPH04103599A (ja) * | 1990-08-22 | 1992-04-06 | Toray Ind Inc | 融合ポリペプチド |
| CA2089553C (en) * | 1990-08-29 | 2000-06-27 | Paul Schendel | Multidomain hematopoiesis stimulators |
| JPH05502463A (ja) * | 1990-09-28 | 1993-04-28 | オーソ・フアーマシユーチカル・コーポレーシヨン | ハイブリツド成長因子 |
-
1996
- 1996-04-26 AU AU55147/96A patent/AU705064B2/en not_active Ceased
- 1996-04-26 ES ES96912262T patent/ES2276401T3/es not_active Expired - Lifetime
- 1996-04-26 JP JP53237296A patent/JP3763846B2/ja not_active Expired - Fee Related
- 1996-04-26 CA CA002194070A patent/CA2194070A1/en not_active Abandoned
- 1996-04-26 WO PCT/JP1996/001157 patent/WO1996034016A1/ja not_active Ceased
- 1996-04-26 DE DE69636714T patent/DE69636714T2/de not_active Expired - Fee Related
- 1996-04-26 AT AT96912262T patent/ATE346096T1/de not_active IP Right Cessation
- 1996-04-26 EP EP96912262A patent/EP0783003B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2194070A1 (en) | 1996-10-31 |
| WO1996034016A1 (en) | 1996-10-31 |
| EP0783003A1 (de) | 1997-07-09 |
| ES2276401T3 (es) | 2007-06-16 |
| EP0783003A4 (de) | 1998-01-07 |
| AU5514796A (en) | 1996-11-18 |
| DE69636714T2 (de) | 2007-10-18 |
| EP0783003B1 (de) | 2006-11-22 |
| DE69636714D1 (de) | 2007-01-04 |
| JP3763846B2 (ja) | 2006-04-05 |
| AU705064B2 (en) | 1999-05-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |