DK1539964T3 - Cellectin-komplementaktiverende proteinkimærer - Google Patents

Cellectin-komplementaktiverende proteinkimærer

Info

Publication number
DK1539964T3
DK1539964T3 DK03794818T DK03794818T DK1539964T3 DK 1539964 T3 DK1539964 T3 DK 1539964T3 DK 03794818 T DK03794818 T DK 03794818T DK 03794818 T DK03794818 T DK 03794818T DK 1539964 T3 DK1539964 T3 DK 1539964T3
Authority
DK
Denmark
Prior art keywords
fusion protein
complement
activating
activating protein
cellectin
Prior art date
Application number
DK03794818T
Other languages
Danish (da)
English (en)
Inventor
Leif Kongerslev
Dietmar Weilguny
Finn Matthiesen
Original Assignee
Natimmune As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natimmune As filed Critical Natimmune As
Application granted granted Critical
Publication of DK1539964T3 publication Critical patent/DK1539964T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK03794818T 2002-09-10 2003-09-10 Cellectin-komplementaktiverende proteinkimærer DK1539964T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200201328 2002-09-10
PCT/DK2003/000585 WO2004024925A2 (en) 2002-09-10 2003-09-10 Collectin-complement activating protein chimeras

Publications (1)

Publication Number Publication Date
DK1539964T3 true DK1539964T3 (da) 2007-05-07

Family

ID=31984965

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03794818T DK1539964T3 (da) 2002-09-10 2003-09-10 Cellectin-komplementaktiverende proteinkimærer

Country Status (11)

Country Link
US (1) US20060188963A1 (de)
EP (1) EP1539964B1 (de)
JP (1) JP2005537807A (de)
CN (1) CN1694961A (de)
AT (1) ATE349538T1 (de)
AU (1) AU2003260286A1 (de)
DE (1) DE60310736T2 (de)
DK (1) DK1539964T3 (de)
ES (1) ES2279981T3 (de)
PT (1) PT1539964E (de)
WO (1) WO2004024925A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0522113D0 (en) * 2005-10-28 2005-12-07 Ares Trading Sa vWFA-domain containing proteins
EP2176288B1 (de) 2007-07-10 2015-11-04 Apogenix GmbH Tnf-superfamilie-kollektin-fusionsproteine
CN101918439A (zh) * 2007-11-09 2010-12-15 阿纳福公司 用于治疗疾病的甘露糖结合凝集素融合蛋白
WO2009126346A2 (en) * 2008-01-18 2009-10-15 The General Hospital Corporation Methods for prevention and treatment of infections with supraphysiological doses of mannan-binding lectin (mbl) and ficolin-mbl fusion proteins
DK2380979T3 (da) * 2008-12-22 2015-06-22 Univ Hokkaido Nat Univ Corp Proteinstof med trippelhelixstruktur samt fremgangsmåde til dets fremstilling
JP5844158B2 (ja) * 2009-01-09 2016-01-13 アポゲニクス ゲゼルシャフト ミット ベシュレンクテル ハフツングＡｐｏｇｅｎｉｘ ＧｍｂＨ 三量体形成融合タンパク質
US8993343B2 (en) * 2009-01-28 2015-03-31 Korea Research Institute Of Bioscience And Biotechnology CD93 or use of soluble fragment thereof
US20120282285A1 (en) * 2009-07-17 2012-11-08 Rigshospitalet Masp isoforms as inhibitors of complement activation
CN102947341B (zh) 2010-01-19 2018-07-06 哈佛大学校长及研究员协会 用于病原体检测和治疗的工程化调理素
US8609606B2 (en) 2010-03-04 2013-12-17 Fuso Pharmaceutical Industries, Ltd. Polypeptide acting to enhance ischemic diseases
CA2791841C (en) * 2010-03-05 2023-01-03 Rigshospitalet Chimeric inhibitor molecules of complement activation
WO2013012924A2 (en) 2011-07-18 2013-01-24 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
CN104284984B (zh) 2012-02-29 2017-10-13 哈佛大学校长及研究员协会 抗生素药敏性的快速测试
EP2976642A4 (de) 2013-03-15 2016-09-21 Harvard College Verfahren und zusammensetzungen zur verbesserung der erkennung und/oder aufnahme einer zieleinheit
WO2014190040A1 (en) 2013-05-21 2014-11-27 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
EP3083658B1 (de) 2013-12-18 2019-05-08 President and Fellows of Harvard College Detektion gram-positiver bakterien mit crp
JP2014218510A (ja) * 2014-08-11 2014-11-20 アポゲニクスゲゼルシャフト ミット ベシュレンクテルハフツングＡｐｏｇｅｎｉｘ ＧｍｂＨ 三量体形成融合タンパク質
US10435457B2 (en) 2015-08-06 2019-10-08 President And Fellows Of Harvard College Microbe-binding molecules and uses thereof
JP2016210791A (ja) * 2016-08-03 2016-12-15 アポゲニクス アーゲー 三量体形成融合タンパク質
SG10201802979VA (en) * 2018-04-10 2019-11-28 Kah Meng Lim Immunological extract and method of production
WO2022079308A1 (en) * 2020-10-16 2022-04-21 Institut Pasteur Chimeric constructs useful in vaccination and cancer therapy
CN113307857B (zh) * 2021-01-14 2022-11-01 艾时斌 从表皮生长因子、凝集素和Tat蛋白衍生的支架蛋白
IL311914A (en) * 2021-10-07 2024-06-01 Omeros Corp Complement-activator-targeted catalytic molecules and methods of using them
CN114344453A (zh) * 2022-01-18 2022-04-15 华南师范大学 一种罗非鱼cl-k1在制备预防和/或治疗罗非鱼病害的药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69836428T2 (de) * 1997-08-21 2007-09-27 Takara Bio Inc., Otsu Karzinostatische wirkstoffe
JPH11206378A (ja) * 1998-01-23 1999-08-03 Fuso Pharmaceutical Industries Ltd 組換えヒトマンナン結合タンパク質およびその製造方法
US7049099B2 (en) * 1998-01-23 2006-05-23 Fuso Pharmaceutical Industries, Ltd. Recombinant human mannan-binding proteins and producing method of the same
US6337193B1 (en) * 1998-11-24 2002-01-08 Aptagen, Inc. Expression of manose-binding protein in methylotrophic yeast
EP1181038B1 (de) * 1999-05-14 2004-04-14 Steffen Thiel Neue indikationen für mannan-binding lectin (mbl) zur behandlung von immungeschwächten patienten
US20030186419A1 (en) * 1999-12-02 2003-10-02 Jensenius Jens Christian Masp-3, a complement-fixing enzyme, and uses for it
NZ523900A (en) * 2000-07-13 2004-02-27 Jens Christian Jensenius Isolation and characterisation of a mannan-binding lectin (MBL) associated serine protease (MASP-2) and uses thereof to treat infections
US20050137126A1 (en) * 2003-04-09 2005-06-23 Natlmmune A/S Treatment of SARS in individuals

Also Published As

Publication number Publication date
AU2003260286A1 (en) 2004-04-30
DE60310736T2 (de) 2007-10-11
WO2004024925A2 (en) 2004-03-25
EP1539964B1 (de) 2006-12-27
WO2004024925A8 (en) 2004-05-21
JP2005537807A (ja) 2005-12-15
ES2279981T3 (es) 2007-09-01
WO2004024925A3 (en) 2004-06-24
ATE349538T1 (de) 2007-01-15
CN1694961A (zh) 2005-11-09
PT1539964E (pt) 2007-04-30
US20060188963A1 (en) 2006-08-24
EP1539964A2 (de) 2005-06-15
DE60310736D1 (de) 2007-02-08

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