ATE358493T1 - Menschliche mesenchymale stammzellen aus peripherem blut - Google Patents

Menschliche mesenchymale stammzellen aus peripherem blut

Info

Publication number
ATE358493T1
ATE358493T1 AT98935544T AT98935544T ATE358493T1 AT E358493 T1 ATE358493 T1 AT E358493T1 AT 98935544 T AT98935544 T AT 98935544T AT 98935544 T AT98935544 T AT 98935544T AT E358493 T1 ATE358493 T1 AT E358493T1
Authority
AT
Austria
Prior art keywords
mesenchymal stem
peripheral blood
stem cells
human mesenchymal
individual
Prior art date
Application number
AT98935544T
Other languages
English (en)
Inventor
Mireya Fernandez
Jose J Minguell
Original Assignee
Osiris Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osiris Therapeutics Inc filed Critical Osiris Therapeutics Inc
Application granted granted Critical
Publication of ATE358493T1 publication Critical patent/ATE358493T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98935544T 1997-07-03 1998-07-01 Menschliche mesenchymale stammzellen aus peripherem blut ATE358493T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5165197P 1997-07-03 1997-07-03

Publications (1)

Publication Number Publication Date
ATE358493T1 true ATE358493T1 (de) 2007-04-15

Family

ID=21972574

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98935544T ATE358493T1 (de) 1997-07-03 1998-07-01 Menschliche mesenchymale stammzellen aus peripherem blut

Country Status (11)

Country Link
US (1) US6261549B1 (de)
EP (1) EP1028737B1 (de)
AT (1) ATE358493T1 (de)
AU (1) AU8476698A (de)
CA (1) CA2294944A1 (de)
CY (1) CY1106798T1 (de)
DE (1) DE69837491T2 (de)
DK (1) DK1028737T3 (de)
ES (1) ES2285779T3 (de)
PT (1) PT1028737E (de)
WO (1) WO1999001145A1 (de)

Families Citing this family (174)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9822434D0 (en) * 1998-10-14 1998-12-09 Kennedy Rheumatology Inst Mesenchymal precursor cells
AU766064B2 (en) * 1998-10-26 2003-10-09 Philadelphia Health & Education Corporation Stromal cell use
IL145002A0 (en) * 1999-03-10 2002-06-30 Univ Pittsburgh Adipose-derived stem cells and lattices
US20050076396A1 (en) * 1999-03-10 2005-04-07 Katz Adam J. Adipose-derived stem cells and lattices
US20030082152A1 (en) 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
US20050153442A1 (en) * 1999-03-10 2005-07-14 Adam Katz Adipose-derived stem cells and lattices
US6777231B1 (en) * 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
AU2003901668A0 (en) * 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
US7670628B2 (en) * 1999-07-07 2010-03-02 Angioblast Systems, Inc. Mesenchymal precursor cell
US20050158289A1 (en) * 1999-07-07 2005-07-21 Simmons Paul J. Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals
US8062675B2 (en) 1999-07-07 2011-11-22 Angioblast Systems, Inc. Mesenchymal precursor cell
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
EP2206772A3 (de) 2000-12-06 2010-08-04 Robert J. Hariri Verfahren zum Sammeln von Plazentastammzellen
CA2437957C (en) 2001-02-14 2014-04-22 Robert J. Hariri Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
EP2336299A1 (de) * 2001-02-14 2011-06-22 Anthrogenesis Corporation Post-partum Säugetier-Plazenta, deren Verwendung und daraus gewonnene Stammzellen
FR2820979B1 (fr) * 2001-02-22 2004-03-12 Didier Pourquier Nouvelle application therapeutique du g-csf
US6814961B1 (en) * 2001-05-14 2004-11-09 Gitte S. Jensen Method for enhancing stem cell trafficking
US6723490B2 (en) 2001-11-15 2004-04-20 Kodak Polychrome Graphics Llc Minimization of ablation in thermally imageable elements
US8105580B2 (en) 2001-12-07 2012-01-31 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to promote wound healing
US7514075B2 (en) 2001-12-07 2009-04-07 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating adipose derived stem cells from tissue
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US7595043B2 (en) * 2001-12-07 2009-09-29 Cytori Therapeutics, Inc. Method for processing and using adipose-derived stem cells
US20060204556A1 (en) * 2001-12-07 2006-09-14 Cytori Therapeutics, Inc. Cell-loaded prostheses for regenerative intraluminal applications
US7651684B2 (en) 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US20050008626A1 (en) * 2001-12-07 2005-01-13 Fraser John K. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US20050048036A1 (en) * 2001-12-07 2005-03-03 Hedrick Marc H. Methods of using regenerative cells in the treatment of inherited and acquired disorders of the bone, bone marrow, liver, and other tissues
KR100811995B1 (ko) 2001-12-07 2008-03-10 사이토리 테라퓨틱스, 인크. 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법
US8404229B2 (en) * 2001-12-07 2013-03-26 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to treat acute tubular necrosis
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US7700090B2 (en) 2002-02-13 2010-04-20 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US6830862B2 (en) 2002-02-28 2004-12-14 Kodak Polychrome Graphics, Llc Multi-layer imageable element with a crosslinked top layer
AU2003213666A1 (en) * 2002-03-02 2003-09-16 Board Of Regents, The University Of Texas System Local production and/or delivery of anti-cancer agents by stromal cell precursors
WO2003093433A2 (en) * 2002-05-02 2003-11-13 Regents Of The University Of Minnesota Fibrin-based biomatrix
AU2003259152A1 (en) * 2002-07-23 2004-02-09 Boston Scientific Limited Cell therapy for regeneration
US20040043009A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of repairing primate mammalian tissue
US20040042997A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of regenerating human tissue
US20040076605A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of regenerating human tissue
US20040076620A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of repairing primate mammalian tissue
US20040136969A1 (en) * 2002-10-02 2004-07-15 New York University Adult bone marrow derived stem cells
US20040101959A1 (en) * 2002-11-21 2004-05-27 Olga Marko Treatment of tissue with undifferentiated mesenchymal cells
KR101042448B1 (ko) 2002-11-26 2011-06-16 안트로제네시스 코포레이션 세포요법제, 세포요법제 단위 및 이를 이용한 치료방법
WO2004069172A2 (en) 2003-01-30 2004-08-19 The Government of the United States of America as represented by the Department of Veterans Affairs Multilineage-inducible cells and uses thereof
EP2263698A1 (de) * 2003-04-01 2010-12-22 United States of America Dempartment of Veteran's Affairs Auf Stammzellen, Vorläuferzellen oder Targetzellen basierende Behandlung von Multiorganversagen und Nierenfunktionsstörung
EP1620827B1 (de) * 2003-04-24 2010-06-02 Koninklijke Philips Electronics N.V. Eingriffsfreie links-herzkammervolumenbestimmung
US20060210544A1 (en) 2003-06-27 2006-09-21 Renomedix Institute, Inc. Internally administered therapeutic agents for cranial nerve diseases comprising mesenchymal cells as an active ingredient
KR101130220B1 (ko) * 2003-06-27 2012-04-13 엔씨 메디컬 리서치 가부시키가이샤 간엽계 세포를 유효 성분으로 하는 뇌신경 질환 치료용 체내 투여용 약제
CN101072572B (zh) * 2003-07-09 2013-12-11 华沙整形外科股份有限公司 富含结缔组织生长成分的骨髓组分的分离及其促进结缔组织形成的用途
WO2005113749A2 (en) * 2004-05-14 2005-12-01 Becton, Dickinson And Company Stem cell populations and methods of use
WO2006004910A2 (en) * 2004-06-28 2006-01-12 Transtarget Inc. Improved bispecific antibodies
US8431397B2 (en) * 2004-09-14 2013-04-30 The Trustees Of Columbia University In The City Of New York Differentiation of human mesenchymal stem cells to cardiac progenitor cells that promote cardiac repair
EP2360242A1 (de) * 2004-09-24 2011-08-24 Angioblast Systems, Inc. Verfahren zur Verbesserung der Vermehrung und/oder des Überlebens von Mesenchymalvorläuferzellen (MPC)
US20060111778A1 (en) * 2004-10-29 2006-05-25 Michalow Alexander E Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway
US20090131866A1 (en) * 2004-11-12 2009-05-21 Regents Of The University Of Minnesota Veinous Occlusion Device and Methods of Using
US8017395B2 (en) 2004-12-17 2011-09-13 Lifescan, Inc. Seeding cells on porous supports
CA2512667A1 (en) * 2005-01-07 2006-07-07 Takahiro Ochiya Human hepatocyte-like cells and uses thereof
US20080140451A1 (en) * 2005-01-10 2008-06-12 Cytori Therapeutics, Inc. Devices and Methods for Monitoring, Managing, and Servicing Medical Devices
US20060193839A1 (en) * 2005-02-28 2006-08-31 Donnie Rudd Method of providing readily available cellular material derived from peripheral blood, and a composition thereof
BRPI0520280A2 (pt) * 2005-05-10 2009-04-28 Us Of America Dept Of Veteran terapia de disfunÇÕes renais e falÊncia méltipla de àrgços com cÉlulas-tronco mesenquimais e meio condicionado por exposiÇço a cÉlulas-tronco mesenquimais
AU2006202209B2 (en) * 2005-05-27 2011-04-14 Lifescan, Inc. Amniotic fluid derived cells
EP1888123B1 (de) * 2005-06-08 2013-01-09 Janssen Biotech, Inc. Zelltherapie für augendegeneration
AU2006265601A1 (en) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
US7928280B2 (en) * 2005-07-13 2011-04-19 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
US7531355B2 (en) 2005-07-29 2009-05-12 The Regents Of The University Of California Methods and compositions for smooth muscle reconstruction
CA2624925C (en) 2005-10-13 2014-09-30 Anthrogenesis Corporation Immunomodulation using placental stem cells
JP2009517343A (ja) * 2005-11-14 2009-04-30 エンタープライズ パートナーズ ベンチャー キャピタル 組織損傷のための幹細胞因子療法
ES2708933T3 (es) 2005-12-29 2019-04-12 Celularity Inc Poblaciones de células madre placentarias
US8741643B2 (en) 2006-04-28 2014-06-03 Lifescan, Inc. Differentiation of pluripotent stem cells to definitive endoderm lineage
JP2009535347A (ja) * 2006-04-28 2009-10-01 テュレーン・ユニバーシティ・ヘルス・サイエンシーズ・センター 糖尿病の治療方法
WO2007139551A1 (en) * 2006-05-30 2007-12-06 Cytori Therapeutics, Inc. Systems and methods for manipulation of regenerative cells from adipose tissue
WO2007146105A2 (en) * 2006-06-05 2007-12-21 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of fetal placental cells
WO2007146123A2 (en) * 2006-06-09 2007-12-21 Anthrogenesis Corporation Placental niche and use thereof to culture stem cells
CA2655990A1 (en) * 2006-06-22 2007-12-27 Tai June Yoo Restoration of hearing loss
WO2008013863A2 (en) * 2006-07-26 2008-01-31 Cytori Therapeutics, Inc. Generation of adipose tissue and adipocytes
JP2010500047A (ja) 2006-08-15 2010-01-07 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 間葉系幹細胞馴化培地
WO2008021391A1 (en) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US20080058922A1 (en) * 2006-08-31 2008-03-06 Cardiac Pacemakers, Inc. Methods and devices employing vap-1 inhibitors
US8636995B2 (en) * 2006-08-31 2014-01-28 Cardiac Pacemakers, Inc. Methods and devices to regulate stem cell homing
US8372399B2 (en) * 2006-08-31 2013-02-12 Cardiac Pacemakers, Inc. Bispecific antibodies and agents to enhance stem cell homing
WO2008042441A1 (en) * 2006-10-03 2008-04-10 Anthrogenesis Corporation Use of umbilical cord biomaterial for ocular surgery
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
AU2007318210B2 (en) * 2006-10-06 2014-02-20 Celularity Inc. Native (telopeptide) placental collagen compositions
US20080124318A1 (en) * 2006-11-28 2008-05-29 Jerold Lisson Algae supplement and treatment method
US20080124286A1 (en) * 2006-11-28 2008-05-29 Lisson Jerold B Algae supplement and treatment method
CA2677273A1 (en) * 2007-02-06 2008-08-14 Tai-June Yoo Use of a composition comprising a cytokine encoding nucleic acid for treating alzheimer's disease
KR101569168B1 (ko) 2007-02-12 2015-11-13 안트로제네시스 코포레이션 태반 줄기세포를 이용한 염증 질환의 치료
US9080145B2 (en) 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
US9096832B2 (en) 2007-07-31 2015-08-04 Lifescan, Inc. Differentiation of human embryonic stem cells
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
ES2326772B1 (es) * 2007-09-26 2010-07-26 Fundacion Progreso Y Salud Procedimiento de obtencion de celulas madre mesenquimales con capacidad pluripotente.
CA2700617C (en) 2007-09-28 2018-11-06 Celgene Cellular Therapeutics Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
ATE523585T1 (de) 2007-11-27 2011-09-15 Lifescan Inc Differenzierung menschlicher embryonaler stammzellen
CA2959401C (en) 2008-02-21 2021-12-07 Centocor Ortho Biotech Inc. Methods, surface modified plates and compositions for cell attachment, cultivation and detachment
SG188918A1 (de) 2008-03-17 2013-04-30 Agency Science Tech & Res
US8623648B2 (en) * 2008-04-24 2014-01-07 Janssen Biotech, Inc. Treatment of pluripotent cells
KR101651661B1 (ko) 2008-06-30 2016-08-26 얀센 바이오테크 인코포레이티드 만능 줄기 세포의 분화
EP2318516A1 (de) * 2008-06-30 2011-05-11 Centocor Ortho Biotech Inc. Differenzierung pluripotenter stammzellen
US20100028307A1 (en) * 2008-07-31 2010-02-04 O'neil John J Pluripotent stem cell differentiation
WO2010021993A1 (en) * 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
DK2330889T3 (en) 2008-08-20 2017-01-30 Anthrogenesis Corp Improved cell composition and process for making the same
WO2010031006A1 (en) 2008-09-12 2010-03-18 Cryopraxis Criobiologia Ltda. Ischemic tissue cell therapy
MX2011004563A (es) * 2008-10-31 2011-06-01 Centocor Ortho Biotech Inc Diferenciacion de celulas madre embrionarias humanas al linaje endocrino pancreatico.
CN102272291B (zh) * 2008-10-31 2018-01-16 詹森生物科技公司 人胚胎干细胞向胰腺内分泌谱系的分化
CN102282252B (zh) 2008-11-19 2017-07-04 人类起源公司 羊膜来源的贴壁细胞
PL2366022T3 (pl) * 2008-11-20 2016-11-30 Sposoby i kompozycje do przyłączania i hodowli komórek na podłożach planarnych
PL2366021T3 (pl) 2008-11-20 2017-12-29 Janssen Biotech, Inc. Hodowla pluripotencjalnych komórek macierzystych na mikronośnikach
US8790638B2 (en) * 2009-02-04 2014-07-29 Stemedica Cell Technologies, Inc. Compositions of stem cells and stem cell factors and methods for their use and manufacture
US9301975B2 (en) 2009-05-01 2016-04-05 Biocardia, Inc. Method of preparing autologous cells and method of use for therapy
WO2010127310A1 (en) * 2009-05-01 2010-11-04 Cytori Therapeutics, Inc. Systems, methods and compositions for optimizing tissue and cell enriched grafts
KR20170118969A (ko) 2009-07-20 2017-10-25 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
ES2693088T3 (es) * 2009-07-20 2018-12-07 Janssen Biotech, Inc. Diferenciación de células madre embriónicas humanas
AU2010276402B2 (en) * 2009-07-20 2014-07-03 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
CN102695790A (zh) * 2009-10-29 2012-09-26 詹森生物科技公司 多能干细胞
MX339669B (es) * 2009-12-23 2016-06-02 Janssen Biotech Inc Diferenciacion de celulas madres embrionarias humanas.
AU2010333839C1 (en) * 2009-12-23 2016-07-21 Janssen Biotech Inc. Differentiation of human embryonic stem cells
CN107189979B (zh) * 2010-03-01 2021-05-04 詹森生物科技公司 纯化衍生自多能干细胞的细胞的方法
IL250234B2 (en) 2010-04-07 2023-10-01 Anthrogenesis Llc Angiogenesis using placental stem cells
MX2012011543A (es) 2010-04-08 2013-05-06 Anthrogenesis Corp Tratamiento de sarcoidosis empleando celulas madre placentarias.
KR101986176B1 (ko) 2010-05-12 2019-06-05 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
US9206387B2 (en) 2010-07-09 2015-12-08 The Gid Group, Inc. Method and apparatus for processing adipose tissue
EP2590695B1 (de) 2010-07-09 2024-11-20 GID BIO, Inc. Vorrichtung und verfahren zur erhebung und verarbeitung von menschlichem biologischem material mit fettgewebe
US9296984B2 (en) 2010-07-09 2016-03-29 The Gid Group, Inc. Tissue processing apparatus and method for processing adipose tissue
WO2013106655A1 (en) 2012-01-11 2013-07-18 The Gid Group, Inc. Method for processing adipose tissue and processing apparatus
KR20180099915A (ko) 2010-07-13 2018-09-05 안트로제네시스 코포레이션 천연 킬러 세포의 생성 방법
WO2012030539A2 (en) 2010-08-31 2012-03-08 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
AU2011296381B2 (en) 2010-08-31 2016-03-31 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
WO2012030540A2 (en) 2010-08-31 2012-03-08 Janssen Biotech, Inc. Differentiation of pluripotent stem cells
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
EP4663241A3 (de) 2010-10-08 2026-03-25 Mesoblast International Sàrl Verbesserte msc-zubereitungen
ES2384790B1 (es) * 2010-12-10 2013-05-20 Instituto De Salud Carlos Iii Células madre mesenquimales aisladas a partir de sangre periférica.
AU2011352036A1 (en) 2010-12-31 2013-07-18 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
US9164079B2 (en) 2011-03-17 2015-10-20 Greyledge Technologies Llc Systems for autologous biological therapeutics
CN104220081A (zh) 2011-06-01 2014-12-17 人类起源公司 利用胎盘干细胞治疗疼痛
CA2840307C (en) 2011-07-06 2021-10-19 Cell Therapy Limited Progenitor cells of mesodermal lineage
WO2013055476A1 (en) 2011-09-09 2013-04-18 Anthrogenesis Corporation Treatment of amyotrophic lateral sclerosis using placental stem cells
EP2773746A4 (de) * 2011-11-01 2015-08-05 Neostem Inc Adulte mesenchymale stammzellenzusammensetzungen und verfahren zu ihrer herstellung
US9388386B2 (en) 2011-12-22 2016-07-12 Janssen Biotech, Inc. Differentiation of human embryonic stem cells into single hormonal insulin positive cells
CA2866590A1 (en) 2012-03-07 2013-09-12 Janssen Biotech, Inc. Defined media for expansion and maintenance of pluripotent stem cells
WO2013184888A1 (en) 2012-06-08 2013-12-12 Janssen Biotech, Inc. Differentiation of human embryonic stem cells into pancreatic endocrine cells
BR112015004003B1 (pt) 2012-09-06 2020-05-19 The Gid Group, Inc. aparelho para processar material biológico humano contendo tecido fibroso e método para processar tecido adiposo
WO2014105543A1 (en) 2012-12-31 2014-07-03 Janssen Biotech, Inc. Culturing of human embryonic stem cells at the air-liquid interface for differentiation into pancreatic endocrine cells
RU2687379C2 (ru) 2012-12-31 2019-05-13 Янссен Байотек, Инк. Суспендирование и кластеризация плюрипотентных клеток человека с целью их дифференцировки в панкреатические эндокринные клетки
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
RU2684215C2 (ru) 2012-12-31 2019-04-04 Янссен Байотек, Инк. Способ получения панкреатических эндокринных клеток (варианты) и способ увеличения выхода бета-клеток
AU2014215458A1 (en) 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
WO2015035221A1 (en) 2013-09-05 2015-03-12 The Gid Group, Inc. Tissue processing apparatus and method for processing adipose tissue
US20150093367A1 (en) * 2013-09-27 2015-04-02 Global Health Solutions Research Trust Acupoint injection therapy using an enriched cellular mixture
JP6612227B2 (ja) 2013-11-16 2019-11-27 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
WO2015167768A1 (en) 2014-05-02 2015-11-05 Lifecell Corporation Injection sensor with feedback mechanism
JP6588969B2 (ja) 2014-05-16 2019-10-09 ヤンセン バイオテツク,インコーポレーテツド 膵内分泌細胞内のmafa発現を強化するための小分子の使用
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
BR112018008050A2 (pt) 2015-10-21 2018-10-23 Lifecell Corp sistemas e métodos para gerenciamento de tubo
RU2728181C2 (ru) 2015-10-21 2020-07-28 Лайфселл Корпорейшн Системы и способы для управления изделиями медицинского назначения
US10729827B2 (en) 2015-12-22 2020-08-04 Lifecell Corporation Syringe filling device for fat transfer
US11654159B2 (en) 2016-04-06 2023-05-23 University Of Florida Research Foundation, Inc. Therapeutic use of electroacupuncture-induced mesenchymal stem cells
JP6705911B2 (ja) 2016-04-14 2020-06-03 ヤンセン バイオテツク,インコーポレーテツド 多能性幹細胞の中腸内胚葉細胞への分化
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
WO2018044791A1 (en) 2016-08-30 2018-03-08 Lifecell Corporation Systems and methods for medical device control
USD851777S1 (en) 2017-01-30 2019-06-18 Lifecell Corporation Canister-type device for tissue processing
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
WO2018184028A2 (en) 2017-03-31 2018-10-04 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
WO2018207918A1 (ja) * 2017-05-12 2018-11-15 国立大学法人 東京医科歯科大学 移植効率を向上させる間葉系幹細胞の純化方法
US11732233B2 (en) 2017-07-18 2023-08-22 Gid Bio, Inc. Adipose tissue digestion system and tissue processing method
AU2018372631B2 (en) 2017-11-22 2025-06-05 Mesoblast International Sarl Cellular compositions and methods of treatment I
GB2619893A (en) 2021-03-23 2023-12-20 Terumo Bct Inc Cell capture and expansion
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5199942A (en) 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation

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US6261549B1 (en) 2001-07-17
CA2294944A1 (en) 1999-01-14
EP1028737A1 (de) 2000-08-23
DE69837491D1 (de) 2007-05-16
AU8476698A (en) 1999-01-25
DE69837491T2 (de) 2008-01-17
WO1999001145A1 (en) 1999-01-14
PT1028737E (pt) 2007-07-11
DK1028737T3 (da) 2007-08-13
EP1028737A4 (de) 2002-12-04
ES2285779T3 (es) 2007-11-16

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