NO20001509L - Dannelse av hematopoetiske celler fra multipotente neurale stam-celler - Google Patents
Dannelse av hematopoetiske celler fra multipotente neurale stam-cellerInfo
- Publication number
- NO20001509L NO20001509L NO20001509A NO20001509A NO20001509L NO 20001509 L NO20001509 L NO 20001509L NO 20001509 A NO20001509 A NO 20001509A NO 20001509 A NO20001509 A NO 20001509A NO 20001509 L NO20001509 L NO 20001509L
- Authority
- NO
- Norway
- Prior art keywords
- hematopoietic
- cells
- mnsc
- progeny
- neural stem
- Prior art date
Links
- 210000003958 hematopoietic stem cell Anatomy 0.000 title abstract 2
- 210000001178 neural stem cell Anatomy 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 230000003394 haemopoietic effect Effects 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 2
- 230000001939 inductive effect Effects 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000010322 bone marrow transplantation Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000011134 hematopoietic stem cell transplantation Methods 0.000 abstract 1
- 210000000777 hematopoietic system Anatomy 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/08—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Developmental Biology & Embryology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6028997P | 1997-09-29 | 1997-09-29 | |
| US09/100,679 US6093531A (en) | 1997-09-29 | 1998-06-19 | Generation of hematopoietic cells from multipotent neural stem cells |
| PCT/CA1998/000916 WO1999016863A1 (en) | 1997-09-29 | 1998-09-28 | Generation of hematopoietic cells from multipotent neural stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20001509D0 NO20001509D0 (no) | 2000-03-23 |
| NO20001509L true NO20001509L (no) | 2000-05-23 |
| NO324708B1 NO324708B1 (no) | 2007-12-03 |
Family
ID=26739784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20001509A NO324708B1 (no) | 1997-09-29 | 2000-03-23 | Sammensetning og doseform som omfatter multipotente neurale stamceller, unntatt embryoniske stamceller, samt anvendelse av mammalske multipotente neuralstamcelle-etterkommere. |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6093531A (no) |
| EP (1) | EP1019493B1 (no) |
| JP (1) | JP2001518289A (no) |
| AT (1) | ATE310077T1 (no) |
| AU (1) | AU9249598A (no) |
| CA (1) | CA2304007A1 (no) |
| DE (1) | DE69832402T2 (no) |
| DK (1) | DK1019493T3 (no) |
| ES (1) | ES2255179T3 (no) |
| NO (1) | NO324708B1 (no) |
| WO (1) | WO1999016863A1 (no) |
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|---|---|---|---|---|
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| US20010007657A1 (en) * | 1997-08-04 | 2001-07-12 | Reid James Steven | Compositions and methods for manipulating glial progenitor cells and treating neurological deficits |
| US7795202B2 (en) | 1997-08-04 | 2010-09-14 | Neurorepair, Inc. | Methods for treating a neurological disorder by peripheral administration of a transforming growth factor alpha (TGF-a) |
| WO1999006060A1 (en) | 1997-08-04 | 1999-02-11 | The Regents Of The University Of California | Methods for treating neurological deficits |
| US20020123143A1 (en) * | 1997-08-22 | 2002-09-05 | Jean Toma | Multipotent stem cells from peripheral tissues and uses thereof |
| US20020016002A1 (en) * | 2000-01-24 | 2002-02-07 | Jean Toma | Multipotent neural stem cells from peripheral tissues and uses thereof |
| US6093531A (en) * | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
| US6638501B1 (en) * | 1997-09-29 | 2003-10-28 | Neurospheres Holdings Ltd. | Use of multipotent neural stem cell progeny to augment non-neural tissues |
| SE9802264D0 (sv) * | 1998-06-25 | 1998-06-25 | Neuronova Ab | A method of isolating cells |
| US6541247B1 (en) | 1998-06-25 | 2003-04-01 | Neuronova Ab | Method of isolating ependymal neural stem cells |
| CA2381292C (en) | 1999-08-05 | 2016-05-24 | Mcl Llc | Multipotent adult stem cells and methods for isolation |
| US8252280B1 (en) | 1999-08-05 | 2012-08-28 | Regents Of The University Of Minnesota | MAPC generation of muscle |
| US8075881B2 (en) | 1999-08-05 | 2011-12-13 | Regents Of The University Of Minnesota | Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure |
| US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
| US10638734B2 (en) | 2004-01-05 | 2020-05-05 | Abt Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
| US8609412B2 (en) | 1999-08-05 | 2013-12-17 | Regents Of The University Of Minnesota | Mapc generation of lung tissue |
| ATE473751T1 (de) * | 2000-02-11 | 2010-07-15 | Schepens Eye Res Inst | Isolierung und transplantation von retinalen stammzellen |
| WO2002014469A2 (en) * | 2000-08-15 | 2002-02-21 | Geron Corporation | Reprogramming cells for enhanced differentiation capacity using pluripotent stem cells |
| EP2206772A3 (en) | 2000-12-06 | 2010-08-04 | Robert J. Hariri | Method of collecting placental stem cells |
| US7311905B2 (en) | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
| EP1491093B1 (en) | 2001-02-14 | 2013-07-31 | ABT Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
| EP2336299A1 (en) * | 2001-02-14 | 2011-06-22 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| US7838292B1 (en) * | 2001-03-29 | 2010-11-23 | University Of Louisville Research Foundation, Inc. | Methods for obtaining adult human olfactory progenitor cells |
| US20030017587A1 (en) * | 2001-07-18 | 2003-01-23 | Rader William C. | Embryonic stem cells, clinical applications and methods for expanding in vitro |
| US20030211603A1 (en) * | 2001-08-14 | 2003-11-13 | Earp David J. | Reprogramming cells for enhanced differentiation capacity using pluripotent stem cells |
| US20050064587A1 (en) * | 2001-09-07 | 2005-03-24 | Lawrence Rosenberg | Pancreatic small cells and uses thereof |
| US20030099621A1 (en) * | 2001-11-29 | 2003-05-29 | Robert Chow | Stem cell screening and transplantation therapy for HIV infection |
| DE10162080A1 (de) * | 2001-12-10 | 2003-06-26 | Albrecht Mueller | Verfahren zur Herstellung von Stammzellen mit erhöhtem Entwicklungspotential |
| JP4374469B2 (ja) * | 2002-01-09 | 2009-12-02 | 独立行政法人科学技術振興機構 | 記憶障害治療剤 |
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| WO2004050859A2 (en) | 2002-11-27 | 2004-06-17 | Regents Of The University Of Minnesota | Homologous recombination in multipotent adult progenitor cells |
| US20040219608A1 (en) * | 2003-04-29 | 2004-11-04 | Der-Balian Georges Puzant | Method of cell analysis using small volume of blood |
| DE602004030809D1 (de) * | 2003-09-12 | 2011-02-10 | Stemcell Technologies Inc | Test für neurale koloniebildung |
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| WO2008063675A2 (en) | 2006-11-24 | 2008-05-29 | Regents Of The University Of Minnesota | Endodermal progenitor cells |
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| US5766948A (en) * | 1993-01-06 | 1998-06-16 | The Regents Of The University Of California | Method for production of neuroblasts |
| US6432711B1 (en) * | 1993-11-03 | 2002-08-13 | Diacrin, Inc. | Embryonic stem cells capable of differentiating into desired cell lines |
| JP3952508B2 (ja) * | 1993-11-09 | 2007-08-01 | ニューロスフィアーズ ホウルディングス リミテッド | 中枢神経系の幹細胞の原位置修飾及び操作 |
| US5591625A (en) * | 1993-11-24 | 1997-01-07 | Case Western Reserve University | Transduced mesenchymal stem cells |
| US5639618A (en) * | 1994-05-13 | 1997-06-17 | Plurion, Inc. | Method of isolating a lineage specific stem cell in vitro |
| WO1996015226A1 (en) * | 1994-11-14 | 1996-05-23 | Neurospheres Holdings Ltd. | Regulation of neural stem cell proliferation |
| US6890724B2 (en) * | 1996-09-06 | 2005-05-10 | California Institute Of Technology | Methods and compositions for neural progenitor cells |
| US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
| US6093531A (en) * | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
| US6638501B1 (en) * | 1997-09-29 | 2003-10-28 | Neurospheres Holdings Ltd. | Use of multipotent neural stem cell progeny to augment non-neural tissues |
-
1998
- 1998-06-19 US US09/100,679 patent/US6093531A/en not_active Expired - Fee Related
- 1998-09-28 JP JP2000513934A patent/JP2001518289A/ja active Pending
- 1998-09-28 DE DE69832402T patent/DE69832402T2/de not_active Expired - Fee Related
- 1998-09-28 CA CA002304007A patent/CA2304007A1/en not_active Abandoned
- 1998-09-28 ES ES98944943T patent/ES2255179T3/es not_active Expired - Lifetime
- 1998-09-28 DK DK98944943T patent/DK1019493T3/da active
- 1998-09-28 AT AT98944943T patent/ATE310077T1/de not_active IP Right Cessation
- 1998-09-28 WO PCT/CA1998/000916 patent/WO1999016863A1/en not_active Ceased
- 1998-09-28 EP EP98944943A patent/EP1019493B1/en not_active Expired - Lifetime
- 1998-09-28 AU AU92495/98A patent/AU9249598A/en not_active Abandoned
-
2000
- 2000-03-23 NO NO20001509A patent/NO324708B1/no unknown
- 2000-07-24 US US09/624,199 patent/US6897060B1/en not_active Expired - Fee Related
-
2003
- 2003-02-21 US US10/371,779 patent/US7204979B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69832402D1 (de) | 2005-12-22 |
| AU9249598A (en) | 1999-04-23 |
| CA2304007A1 (en) | 1999-04-08 |
| US20030148515A1 (en) | 2003-08-07 |
| US7204979B2 (en) | 2007-04-17 |
| US6897060B1 (en) | 2005-05-24 |
| EP1019493A1 (en) | 2000-07-19 |
| NO20001509D0 (no) | 2000-03-23 |
| ATE310077T1 (de) | 2005-12-15 |
| NO324708B1 (no) | 2007-12-03 |
| JP2001518289A (ja) | 2001-10-16 |
| US6093531A (en) | 2000-07-25 |
| EP1019493B1 (en) | 2005-11-16 |
| DE69832402T2 (de) | 2006-08-10 |
| DK1019493T3 (da) | 2006-04-03 |
| ES2255179T3 (es) | 2006-06-16 |
| WO1999016863A1 (en) | 1999-04-08 |
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