ATE363539T1 - Veränderte kluveromyces hefe ihre herstellung und verwendung - Google Patents

Veränderte kluveromyces hefe ihre herstellung und verwendung

Info

Publication number
ATE363539T1
ATE363539T1 AT93913176T AT93913176T ATE363539T1 AT E363539 T1 ATE363539 T1 AT E363539T1 AT 93913176 T AT93913176 T AT 93913176T AT 93913176 T AT93913176 T AT 93913176T AT E363539 T1 ATE363539 T1 AT E363539T1
Authority
AT
Austria
Prior art keywords
kluveromyces
yeast
modified
production
yeasts
Prior art date
Application number
AT93913176T
Other languages
English (en)
Inventor
Reinhard Fleer
Alain Fournier
Patrice Yeh
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE363539T1 publication Critical patent/ATE363539T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT93913176T 1992-06-25 1993-06-23 Veränderte kluveromyces hefe ihre herstellung und verwendung ATE363539T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9207785A FR2692907B1 (fr) 1992-06-25 1992-06-25 Levures kluyveromyces modifiees, preparation et utilisation.

Publications (1)

Publication Number Publication Date
ATE363539T1 true ATE363539T1 (de) 2007-06-15

Family

ID=9431166

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93913176T ATE363539T1 (de) 1992-06-25 1993-06-23 Veränderte kluveromyces hefe ihre herstellung und verwendung

Country Status (13)

Country Link
US (2) USRE37447E1 (de)
EP (1) EP0672150B1 (de)
JP (1) JPH07508166A (de)
AT (1) ATE363539T1 (de)
AU (1) AU4333793A (de)
CA (1) CA2139117A1 (de)
DE (1) DE69334143T2 (de)
DK (1) DK0672150T3 (de)
ES (1) ES2287928T3 (de)
FI (1) FI120589B (de)
FR (1) FR2692907B1 (de)
PT (1) PT672150E (de)
WO (1) WO1994000579A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL116696A (en) * 1995-01-25 1999-08-17 Bio Technology General Corp Production of enzymatically active recombinant carboxypeptidase b
EP0852625A2 (de) * 1995-09-25 1998-07-15 Chiron Corporation Sekretorische 'leader'-sequenz aus pichia zur protein-expression
US6110703A (en) * 1996-07-05 2000-08-29 Novo Nordisk A/S Method for the production of polypeptides
JP2000078978A (ja) * 1998-09-04 2000-03-21 Kirin Brewery Co Ltd プロテアーゼ活性の低下したカンジダ・ボイジニ株及び異種タンパク質製造用宿主としてのその使用
US7517671B2 (en) 2002-02-28 2009-04-14 New England Biolabs, Inc. Methods and compositions for concentrating secreted recombinant protein
AR107872A1 (es) * 2016-03-16 2018-06-13 Godo Sushei Co Ltd Proteinasa b y solución de lactasa usando sus propiedades y método para producirlo
MX2019009124A (es) * 2017-02-02 2019-09-27 Lallemand Hungary Liquidity Man Llc Expresion de proteasa heterologa para mejorar la fermentacion alcoholica.
CN113717874B (zh) * 2021-09-27 2023-04-11 四川大学 一种耐高温、耐高糖的酿酒酵母菌株及其构建方法和应用
US20250283029A1 (en) * 2022-05-02 2025-09-11 North Carolina State University Engineered microorganisms with enhanced protein expression and secretion

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0240224A3 (de) * 1986-03-31 1989-02-01 Interferon Sciences, Inc. Alpha-Interferon-Analogon
ES2061632T5 (es) * 1987-07-28 2000-12-16 Dsm Nv Kluyveromyces como celula hospedante.
EP0327797B1 (de) * 1988-01-05 2003-09-03 Roche Diagnostics GmbH Verfahren zur Herstellung von Proteinen oder proteinhaltigen Genprodukten
DE68922014T2 (de) * 1988-01-27 1995-08-03 M & D Research Co Protease.
BE1004360A3 (fr) * 1989-03-31 1992-11-10 Debergh Ludo Dispositif de fermeture etanche pour regard.
FR2645175B1 (fr) * 1989-03-31 1994-02-18 Transgene Sa Souche de saccharomyces cerevisiaeproductrice d'une proteine heterologue et procede de preparation de ladite proteine heterologue par fermentation de ladite souche
EP0578746B1 (de) 1991-04-01 2002-07-03 Merck & Co., Inc. Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung

Also Published As

Publication number Publication date
JPH07508166A (ja) 1995-09-14
USRE37447E1 (en) 2001-11-13
EP0672150B1 (de) 2007-05-30
EP0672150A1 (de) 1995-09-20
DK0672150T3 (da) 2007-10-08
CA2139117A1 (fr) 1994-01-06
DE69334143T2 (de) 2008-01-31
WO1994000579A1 (fr) 1994-01-06
PT672150E (pt) 2007-09-07
FI120589B (fi) 2009-12-15
DE69334143D1 (de) 2007-07-12
FR2692907B1 (fr) 1995-06-30
ES2287928T3 (es) 2007-12-16
FI946076A0 (fi) 1994-12-23
US5679544A (en) 1997-10-21
FR2692907A1 (fr) 1993-12-31
AU4333793A (en) 1994-01-24
FI946076L (fi) 1994-12-23

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