ATE364374T1 - Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit - Google Patents

Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit

Info

Publication number
ATE364374T1
ATE364374T1 AT98305960T AT98305960T ATE364374T1 AT E364374 T1 ATE364374 T1 AT E364374T1 AT 98305960 T AT98305960 T AT 98305960T AT 98305960 T AT98305960 T AT 98305960T AT E364374 T1 ATE364374 T1 AT E364374T1
Authority
AT
Austria
Prior art keywords
solid pharmaceutical
increased bioavailability
pharmaceutical dispersions
dispersions
biavailability
Prior art date
Application number
AT98305960T
Other languages
English (en)
Inventor
William John Curatolo
Scott Max Herbig
James Alan Schrive Nightingale
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21996463&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE364374(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE364374T1 publication Critical patent/ATE364374T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/02—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/005—Separating solid material from the gas/liquid stream

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT98305960T 1997-08-11 1998-07-27 Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit ATE364374T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5522197P 1997-08-11 1997-08-11

Publications (1)

Publication Number Publication Date
ATE364374T1 true ATE364374T1 (de) 2007-07-15

Family

ID=21996463

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98305960T ATE364374T1 (de) 1997-08-11 1998-07-27 Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit

Country Status (14)

Country Link
US (7) US8263128B2 (de)
EP (1) EP0901786B1 (de)
JP (1) JP2984661B2 (de)
CN (3) CN1207896A (de)
AT (1) ATE364374T1 (de)
BR (1) BR9803144A (de)
CA (1) CA2245269C (de)
CY (1) CY1107726T1 (de)
DE (1) DE69837903T2 (de)
DK (1) DK0901786T3 (de)
ES (1) ES2287971T3 (de)
IL (1) IL125627A (de)
PT (1) PT901786E (de)
TW (1) TWI230079B (de)

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EP0901786A2 (de) 1999-03-17
JP2984661B2 (ja) 1999-11-29
CN1207896A (zh) 1999-02-17
US8263128B2 (en) 2012-09-11
EP0901786B1 (de) 2007-06-13
US20120328679A1 (en) 2012-12-27
IL125627A0 (en) 1999-04-11
US20020009494A1 (en) 2002-01-24
PT901786E (pt) 2007-08-07
BR9803144A (pt) 2000-01-11
JPH11116502A (ja) 1999-04-27
EP0901786A3 (de) 2000-01-19
ES2287971T3 (es) 2007-12-16
CN1981742A (zh) 2007-06-20
US8257741B2 (en) 2012-09-04
DE69837903T2 (de) 2008-02-14
CA2245269A1 (en) 1999-02-11
US20130224301A1 (en) 2013-08-29
CA2245269C (en) 2003-01-28
US8367118B2 (en) 2013-02-05
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DK0901786T3 (da) 2007-10-08
DE69837903D1 (de) 2007-07-26
CN101450212A (zh) 2009-06-10
IL125627A (en) 2009-02-11
US8337899B2 (en) 2012-12-25
US20120288542A1 (en) 2012-11-15
US20120292797A1 (en) 2012-11-22
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CY1107726T1 (el) 2013-04-18
US20030219489A1 (en) 2003-11-27

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