ATE367818T1 - Anionische polymer als toxinbindemittels und antibacterische mittel - Google Patents
Anionische polymer als toxinbindemittels und antibacterische mittelInfo
- Publication number
- ATE367818T1 ATE367818T1 AT00930620T AT00930620T ATE367818T1 AT E367818 T1 ATE367818 T1 AT E367818T1 AT 00930620 T AT00930620 T AT 00930620T AT 00930620 T AT00930620 T AT 00930620T AT E367818 T1 ATE367818 T1 AT E367818T1
- Authority
- AT
- Austria
- Prior art keywords
- antibacteric
- toxin
- agents
- anionic polymers
- toxin binders
- Prior art date
Links
- 239000003053 toxin Substances 0.000 title abstract 3
- 231100000765 toxin Toxicity 0.000 title abstract 3
- 229920006318 anionic polymer Polymers 0.000 title 1
- 239000011230 binding agent Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 229920000642 polymer Polymers 0.000 abstract 3
- 125000006850 spacer group Chemical group 0.000 abstract 2
- OTLLEIBWKHEHGU-UHFFFAOYSA-N 2-[5-[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-4-phosphonooxyhexanedioic acid Chemical compound C1=NC=2C(N)=NC=NC=2N1C(C(C1O)O)OC1COC1C(CO)OC(OC(C(O)C(OP(O)(O)=O)C(O)C(O)=O)C(O)=O)C(O)C1O OTLLEIBWKHEHGU-UHFFFAOYSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 231100000776 exotoxin Toxicity 0.000 abstract 1
- 239000002095 exotoxin Substances 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 244000000010 microbial pathogen Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/795—Polymers containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Detergent Compositions (AREA)
- Absorbent Articles And Supports Therefor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13397599P | 1999-05-13 | 1999-05-13 | |
| US09/541,268 US6270755B1 (en) | 1999-05-13 | 2000-04-03 | Anionic polymers as toxin binders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE367818T1 true ATE367818T1 (de) | 2007-08-15 |
Family
ID=26831853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00930620T ATE367818T1 (de) | 1999-05-13 | 2000-05-11 | Anionische polymer als toxinbindemittels und antibacterische mittel |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6270755B1 (de) |
| EP (1) | EP1189622B1 (de) |
| JP (1) | JP2002544226A (de) |
| KR (1) | KR100742433B1 (de) |
| CN (1) | CN100435806C (de) |
| AT (1) | ATE367818T1 (de) |
| AU (1) | AU768592B2 (de) |
| BR (1) | BR0011520A (de) |
| CA (1) | CA2374108A1 (de) |
| DE (1) | DE60035689T2 (de) |
| DK (1) | DK1189622T3 (de) |
| ES (1) | ES2288855T3 (de) |
| HK (1) | HK1044490A1 (de) |
| HU (1) | HUP0201114A3 (de) |
| IL (2) | IL146211A0 (de) |
| MY (1) | MY132695A (de) |
| NO (1) | NO329497B1 (de) |
| NZ (1) | NZ515226A (de) |
| PL (1) | PL197157B1 (de) |
| PT (1) | PT1189622E (de) |
| RU (1) | RU2246938C2 (de) |
| TW (1) | TW592704B (de) |
| WO (1) | WO2000069428A2 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6290946B1 (en) * | 1999-05-13 | 2001-09-18 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders and antibacterial agents |
| US6270755B1 (en) * | 1999-05-13 | 2001-08-07 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders |
| US6805857B2 (en) * | 2000-03-06 | 2004-10-19 | Kumarpal A. Shah | Method of modulating factor D, factor H and CD4 cell immune response with a polystyrene sulfonate, alginate, and saline infusion solution |
| CA2314494A1 (en) * | 2000-05-02 | 2001-11-02 | Geltex Pharmaceuticals, Inc. | Anionic polymers as species specific antibacterial agents |
| US6537538B2 (en) * | 2000-12-18 | 2003-03-25 | Rush-Presbyterian-St. Luke's Medical Center | Method for the prevention, inhibition, or treatment of vaginitis and/or bacterial vaginosis using polystyrene sulfonate |
| EP1542706A1 (de) * | 2002-07-22 | 2005-06-22 | Genzyme Corporation | Poly (kalium- und natriumstyrolsulfonat), seine herstellung und verwendungszwecke |
| US20040106590A1 (en) * | 2002-08-29 | 2004-06-03 | Barry Eisenstein | Methods and reagents for treating infections of clostridium difficile and diseases associated therewith |
| US7682631B2 (en) * | 2003-10-01 | 2010-03-23 | Clemson University | Adhesin-specific nanoparticles and process for using same |
| AU2004285450B2 (en) | 2003-10-20 | 2010-01-14 | Gregory K. Frykman | Zeolite molecular sieves for the removal of toxins |
| US20060099169A1 (en) * | 2004-10-13 | 2006-05-11 | Ilypsa, Inc. | Toxin binding compositions |
| US20060078534A1 (en) * | 2004-10-13 | 2006-04-13 | Dominique Charmot | Toxin binding compositions |
| US8088400B2 (en) * | 2005-08-22 | 2012-01-03 | Quick-Med Technologies, Inc. | Disinfectant with quarternary ammonium polymer and copolymers |
| EP1956899B1 (de) * | 2005-11-02 | 2015-09-09 | Oplon, Pure Science Ltd | Zusammensetzungen und verfahren für die abtötung von zellen |
| RU2308486C1 (ru) * | 2006-04-10 | 2007-10-20 | Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Московская Государственная Академия Ветеринарной Медицины И Биотехнологии Имени К.И. Скрябина" | Способ получения иммобилизованной липазы |
| TW200829286A (en) * | 2006-09-06 | 2008-07-16 | Genzyme Corp | Polystyrene sulfonate polymer tablets, their preparation and use |
| US8809444B2 (en) * | 2009-12-23 | 2014-08-19 | Momentive Performance Materials Inc. | Network copolymer crosslinked emulsions and demulsifying compositions comprising the same |
| JP5820112B2 (ja) * | 2010-12-15 | 2015-11-24 | 積水化学工業株式会社 | インフルエンザウイルス感染阻止剤、インフルエンザウイルス感染阻止塗料及びインフルエンザウイルス感染阻止製品 |
| CN102160870B (zh) * | 2011-03-18 | 2013-04-24 | 南京欧睿医药科技有限公司 | 聚(4-苯乙烯磺酸-共聚-马来酸)钠盐的用途及其药物组合物 |
| CN103842083B (zh) * | 2011-09-08 | 2016-12-21 | 安全Bt股份有限公司 | 改性的中空纤维材料用于从优选血液和血浆的液体中除去由大肠杆菌产生的外毒素的用途及它们用于治疗伴随疾病的用途 |
| RU2482883C1 (ru) * | 2012-03-12 | 2013-05-27 | Федеральное государственное бюджетное учреждение науки Институт высокомолекулярных соединений Российской академии наук | Способ получения полимерно-композиционных волокнистых материалов с антимикробной активностью |
| EP3236940B1 (de) * | 2014-12-23 | 2020-02-05 | Ardelyx, Inc. | Zusammensetzungen und verfahren zur behandlung von hyperkaliämie |
| KR101720053B1 (ko) | 2015-04-30 | 2017-03-27 | 이현국 | 고주파 열처리 장치 및 고주파 열처리 방법 |
| DE102022132913A1 (de) | 2022-12-12 | 2024-06-13 | Forschungszentrum Jülich GmbH | Block-Copolymer, Verfahren zur Herstellung eines Block-Copolymers, Membran und Verwendung einer Membran |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3224941A (en) | 1963-01-21 | 1965-12-21 | Lilly Co Eli | Resin compositions and method for controlling diarrhea |
| US3466365A (en) | 1967-07-24 | 1969-09-09 | White Lab Inc | Antiviral compositions and method of use |
| NL7401542A (de) * | 1973-02-09 | 1974-08-13 | ||
| IE44690B1 (en) | 1976-02-04 | 1982-02-24 | Rohm & Haas | Pharmaceutical compositions containing polyvinylbenzenosulfonic acids |
| US4395392A (en) | 1980-06-24 | 1983-07-26 | Adria Laboratories Inc. | Method for treating kidney stones |
| US4362711A (en) | 1980-07-11 | 1982-12-07 | Evreka Inc. | Blood cholesterol level reducing agent and method |
| US5171738A (en) | 1982-10-04 | 1992-12-15 | Toray Industries, Inc. | Method of treating malignant tumors |
| US5435821A (en) | 1985-12-12 | 1995-07-25 | Exxon Research & Engineering Co. | Controlled release vegetation enhancement agents coated with sulfonated polymers, method of production and prcesses of use |
| US5071759A (en) | 1986-05-30 | 1991-12-10 | The United States Of America As Represented By The Secretary Of The Army | Hybridoma cell lines and monoclonal antibodies to clostridum difficile toxins A and B |
| US5091171B2 (en) * | 1986-12-23 | 1997-07-15 | Tristrata Inc | Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use |
| JPS6422551A (en) * | 1987-07-16 | 1989-01-25 | Dainippon Ink & Chemicals | Composite film for lid |
| IL90388A (en) | 1988-05-26 | 1993-08-18 | Duphar Int Res | Pharmaceutical compositions having anti- endotoxic activity containing a novel active fraction from lactulose syrup, and a method for its preparation |
| JPH02176351A (ja) | 1988-12-27 | 1990-07-09 | Matsushita Electric Ind Co Ltd | 給湯器 |
| US5149523A (en) | 1989-06-20 | 1992-09-22 | Aktiebolaget Hassle | Polystyrenesulfonate-drug complex and solid dosage forms thereof |
| US5093130A (en) | 1989-09-26 | 1992-03-03 | Plant Genetics | Powder coated hydrogel capsules |
| US5601823A (en) | 1989-10-31 | 1997-02-11 | Ophidian Pharmaceuticals, Inc. | Avian antitoxins to clostridium difficle toxin A |
| US5736139A (en) | 1989-10-31 | 1998-04-07 | Ochidian Pharmaceuticals, Inc. | Treatment of Clostridium difficile induced disease |
| US5231003A (en) | 1990-05-11 | 1993-07-27 | Cambridge Bioscience Corporation | Monoclonal antibodies specific for toxin b of clostridium difficile |
| US5149543A (en) | 1990-10-05 | 1992-09-22 | Massachusetts Institute Of Technology | Ionically cross-linked polymeric microcapsules |
| FR2669535A1 (fr) * | 1990-11-26 | 1992-05-29 | Medgenix Group Sa | Utilisation a titre de medicament de macromolecules polysulfonees. |
| AU2672892A (en) * | 1991-09-17 | 1993-04-27 | Alcon Laboratories, Inc. | Compositions containing quinolone antibiotics and sulfonate of polystyrol |
| US5424063A (en) | 1992-01-09 | 1995-06-13 | The Dow Chemical Company | Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process |
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| EP0779819A1 (de) | 1994-09-06 | 1997-06-25 | Galagen Inc. | Therapeutische behandlung von clostridium difficile verbundene krankheiten |
| WO1996020042A1 (fr) | 1994-12-26 | 1996-07-04 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | ADSORBANT POUR LES ENDOTOXINES, LE FACTEUR α DE NECROSE TUMORALE OU LES INTERLEUKINES, PROCEDE D'ELIMINATION PAR ADSORPTION ET ADSORBEUR |
| US5610023A (en) | 1995-03-31 | 1997-03-11 | Lee Laboratories, Inc. | Method of purification of clostridium difficile toxin A and production of mono-specific antibodies |
| DE19515554C2 (de) | 1995-04-27 | 1999-06-17 | Braun Melsungen Ag | Verwendung eines Mittels und Vorrichtung zur simultanen extrakorporalen Elimination von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus Vollblut oder/und Blutplasma |
| AUPN327695A0 (en) * | 1995-05-30 | 1995-06-22 | Chemeq Pty. Limited | Chemotherapeutic compositions |
| US5700458A (en) * | 1996-09-20 | 1997-12-23 | Geltex Pharmaceuticals Inc. | Acid-functionalized saccharides as polyvalent anti-infectives |
| US5800803A (en) | 1997-02-10 | 1998-09-01 | Colgate-Palmolive Company | Oral composition exhibiting enhanced uptake by dental tissue of noncationic antibacterial agents |
| US6060235A (en) | 1997-09-19 | 2000-05-09 | Geltex Pharmaceuticals, Inc. | Antiviral polymers comprising acid functional groups and hydrophobic groups |
| US6007803A (en) * | 1997-09-19 | 1999-12-28 | Geltex Pharmaceuticals, Inc. | Ionic polymers as toxin binding agents |
| WO1999020285A1 (en) | 1997-10-16 | 1999-04-29 | Sanwa Kagaku Kenkyusho Co., Ltd. | Gel preparations containing polystyrenesulfonate |
| US6270755B1 (en) * | 1999-05-13 | 2001-08-07 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders |
-
2000
- 2000-04-03 US US09/541,268 patent/US6270755B1/en not_active Expired - Lifetime
- 2000-05-09 MY MYPI20001992A patent/MY132695A/en unknown
- 2000-05-10 TW TW089108898A patent/TW592704B/zh not_active IP Right Cessation
- 2000-05-11 IL IL14621100A patent/IL146211A0/xx active IP Right Grant
- 2000-05-11 AU AU48409/00A patent/AU768592B2/en not_active Ceased
- 2000-05-11 PL PL352411A patent/PL197157B1/pl not_active IP Right Cessation
- 2000-05-11 DE DE60035689T patent/DE60035689T2/de not_active Expired - Lifetime
- 2000-05-11 KR KR1020017014459A patent/KR100742433B1/ko not_active Expired - Fee Related
- 2000-05-11 EP EP00930620A patent/EP1189622B1/de not_active Expired - Lifetime
- 2000-05-11 DK DK00930620T patent/DK1189622T3/da active
- 2000-05-11 RU RU2001133465/15A patent/RU2246938C2/ru not_active IP Right Cessation
- 2000-05-11 CA CA002374108A patent/CA2374108A1/en not_active Abandoned
- 2000-05-11 ES ES00930620T patent/ES2288855T3/es not_active Expired - Lifetime
- 2000-05-11 HK HK02106350.9A patent/HK1044490A1/zh unknown
- 2000-05-11 HU HU0201114A patent/HUP0201114A3/hu unknown
- 2000-05-11 BR BR0011520-7A patent/BR0011520A/pt not_active Application Discontinuation
- 2000-05-11 JP JP2000617887A patent/JP2002544226A/ja active Pending
- 2000-05-11 WO PCT/US2000/012943 patent/WO2000069428A2/en not_active Ceased
- 2000-05-11 NZ NZ515226A patent/NZ515226A/en not_active IP Right Cessation
- 2000-05-11 PT PT00930620T patent/PT1189622E/pt unknown
- 2000-05-11 AT AT00930620T patent/ATE367818T1/de not_active IP Right Cessation
- 2000-05-11 CN CNB008075360A patent/CN100435806C/zh not_active Expired - Fee Related
-
2001
- 2001-06-11 US US09/878,843 patent/US6419914B2/en not_active Expired - Fee Related
- 2001-10-28 IL IL146211A patent/IL146211A/en not_active IP Right Cessation
- 2001-11-12 NO NO20015524A patent/NO329497B1/no not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1189622 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |