ATE368026T1 - Selektive modulatoren des durch den peroxisomproliferator aktivierten rezeptors - Google Patents
Selektive modulatoren des durch den peroxisomproliferator aktivierten rezeptorsInfo
- Publication number
- ATE368026T1 ATE368026T1 AT04811083T AT04811083T ATE368026T1 AT E368026 T1 ATE368026 T1 AT E368026T1 AT 04811083 T AT04811083 T AT 04811083T AT 04811083 T AT04811083 T AT 04811083T AT E368026 T1 ATE368026 T1 AT E368026T1
- Authority
- AT
- Austria
- Prior art keywords
- peroxisome proliferator
- selective modulators
- receptor activated
- syndrome
- compound
- Prior art date
Links
- 239000003614 peroxisome proliferator Substances 0.000 title 1
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 abstract 2
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000011580 syndromic disease Diseases 0.000 abstract 2
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Liquid Crystal Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03380288 | 2003-12-15 | ||
| US55063604P | 2004-03-05 | 2004-03-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE368026T1 true ATE368026T1 (de) | 2007-08-15 |
Family
ID=34712592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04811083T ATE368026T1 (de) | 2003-12-15 | 2004-12-08 | Selektive modulatoren des durch den peroxisomproliferator aktivierten rezeptors |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7321056B2 (de) |
| EP (1) | EP1697306B1 (de) |
| JP (1) | JP2007516267A (de) |
| KR (1) | KR100806004B1 (de) |
| CN (1) | CN1886364A (de) |
| AT (1) | ATE368026T1 (de) |
| AU (1) | AU2004303793A1 (de) |
| BR (1) | BRPI0417401A (de) |
| CA (1) | CA2549008A1 (de) |
| CY (1) | CY1106846T1 (de) |
| DE (1) | DE602004007825T2 (de) |
| DK (1) | DK1697306T3 (de) |
| EA (1) | EA009023B1 (de) |
| EC (1) | ECSP066639A (de) |
| ES (1) | ES2289589T3 (de) |
| HR (1) | HRP20070422T3 (de) |
| IL (1) | IL175997A0 (de) |
| MA (1) | MA28399B1 (de) |
| MX (1) | MXPA06006829A (de) |
| NO (1) | NO20063261L (de) |
| PL (1) | PL1697306T3 (de) |
| PT (1) | PT1697306E (de) |
| SI (1) | SI1697306T1 (de) |
| WO (1) | WO2005061441A1 (de) |
| ZA (1) | ZA200604834B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013049621A1 (en) * | 2011-09-29 | 2013-04-04 | The Board Of Regents Of The University Of Oklahoma | Ophthalmic compositions comprising ppar-alpha agonists and methods of production and use thereof |
| CN106310173A (zh) * | 2016-08-24 | 2017-01-11 | 厦门三川利生物科技有限公司 | 含过氧化物酶体增殖物激活受体多维果酸醇及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| AU3670900A (en) * | 1999-04-08 | 2000-11-14 | Sankyo Company Limited | Substituted fused imidazole derivatives |
| AU2002222552A1 (en) * | 2000-11-29 | 2002-06-11 | Kyorin Pharmaceutical Co. Ltd. | Substituted carboxylic acid derivatives |
| WO2002083616A1 (en) * | 2001-04-10 | 2002-10-24 | Sankyo Company, Limited | α-SUBSTITUTED φ-ARYLFATTY ACID DERIVATIVE |
| GB0314079D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| SE0104334D0 (sv) * | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
| CN1662487A (zh) * | 2002-06-19 | 2005-08-31 | 伊莱利利公司 | 酰胺连接基过氧化物酶体增殖物激活受体调节剂 |
-
2004
- 2004-12-08 CA CA002549008A patent/CA2549008A1/en not_active Abandoned
- 2004-12-08 HR HR20070422T patent/HRP20070422T3/xx unknown
- 2004-12-08 CN CNA2004800355126A patent/CN1886364A/zh active Pending
- 2004-12-08 PL PL04811083T patent/PL1697306T3/pl unknown
- 2004-12-08 AT AT04811083T patent/ATE368026T1/de not_active IP Right Cessation
- 2004-12-08 US US10/596,256 patent/US7321056B2/en not_active Expired - Fee Related
- 2004-12-08 MX MXPA06006829A patent/MXPA06006829A/es active IP Right Grant
- 2004-12-08 DK DK04811083T patent/DK1697306T3/da active
- 2004-12-08 BR BRPI0417401-1A patent/BRPI0417401A/pt not_active IP Right Cessation
- 2004-12-08 EA EA200601159A patent/EA009023B1/ru not_active IP Right Cessation
- 2004-12-08 WO PCT/US2004/038232 patent/WO2005061441A1/en not_active Ceased
- 2004-12-08 DE DE602004007825T patent/DE602004007825T2/de not_active Expired - Lifetime
- 2004-12-08 KR KR1020067011758A patent/KR100806004B1/ko not_active Expired - Fee Related
- 2004-12-08 SI SI200430482T patent/SI1697306T1/sl unknown
- 2004-12-08 EP EP04811083A patent/EP1697306B1/de not_active Expired - Lifetime
- 2004-12-08 AU AU2004303793A patent/AU2004303793A1/en not_active Abandoned
- 2004-12-08 ES ES04811083T patent/ES2289589T3/es not_active Expired - Lifetime
- 2004-12-08 JP JP2006545654A patent/JP2007516267A/ja active Pending
- 2004-12-08 PT PT04811083T patent/PT1697306E/pt unknown
-
2006
- 2006-05-29 IL IL175997A patent/IL175997A0/en unknown
- 2006-06-12 ZA ZA200604834A patent/ZA200604834B/en unknown
- 2006-06-14 EC EC2006006639A patent/ECSP066639A/es unknown
- 2006-07-06 MA MA29171A patent/MA28399B1/fr unknown
- 2006-07-13 NO NO20063261A patent/NO20063261L/no not_active Application Discontinuation
-
2007
- 2007-09-05 CY CY20071101149T patent/CY1106846T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20063261L (no) | 2006-09-06 |
| WO2005061441A1 (en) | 2005-07-07 |
| US7321056B2 (en) | 2008-01-22 |
| KR100806004B1 (ko) | 2008-02-26 |
| AU2004303793A1 (en) | 2005-07-07 |
| ES2289589T3 (es) | 2008-02-01 |
| HRP20070422T3 (en) | 2007-11-30 |
| EP1697306A1 (de) | 2006-09-06 |
| CN1886364A (zh) | 2006-12-27 |
| DE602004007825T2 (de) | 2008-04-17 |
| ECSP066639A (es) | 2006-10-25 |
| EP1697306B1 (de) | 2007-07-25 |
| CA2549008A1 (en) | 2005-07-07 |
| ZA200604834B (en) | 2007-11-28 |
| HK1097406A1 (en) | 2007-06-22 |
| PT1697306E (pt) | 2007-10-19 |
| MXPA06006829A (es) | 2006-08-23 |
| IL175997A0 (en) | 2006-10-05 |
| BRPI0417401A (pt) | 2007-05-08 |
| MA28399B1 (fr) | 2007-01-02 |
| PL1697306T3 (pl) | 2007-11-30 |
| CY1106846T1 (el) | 2012-05-23 |
| DE602004007825D1 (de) | 2007-09-06 |
| EA200601159A1 (ru) | 2006-10-27 |
| EA009023B1 (ru) | 2007-10-26 |
| SI1697306T1 (sl) | 2008-02-29 |
| DK1697306T3 (da) | 2007-11-12 |
| US20070066683A1 (en) | 2007-03-22 |
| JP2007516267A (ja) | 2007-06-21 |
| KR20060121192A (ko) | 2006-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |