ATE368027T1 - Bipolare lipide und ihre verwendung zum transport bioaktiver substanzen - Google Patents

Bipolare lipide und ihre verwendung zum transport bioaktiver substanzen

Info

Publication number
ATE368027T1
ATE368027T1 AT00925490T AT00925490T ATE368027T1 AT E368027 T1 ATE368027 T1 AT E368027T1 AT 00925490 T AT00925490 T AT 00925490T AT 00925490 T AT00925490 T AT 00925490T AT E368027 T1 ATE368027 T1 AT E368027T1
Authority
AT
Austria
Prior art keywords
lipids
bioactive substances
bipolar lipids
bipolar
transporting
Prior art date
Application number
AT00925490T
Other languages
English (en)
Inventor
Ian Blagbrough
Andrew John Geall
Michael Anthony William Eaton
Timothy John Norman
Terence Seward Baker
Andrew Neil Charles Weir
Catherine Fiona Catterall
Original Assignee
Celltech R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9909582.0A external-priority patent/GB9909582D0/en
Priority claimed from GBGB9924257.0A external-priority patent/GB9924257D0/en
Application filed by Celltech R&D Ltd filed Critical Celltech R&D Ltd
Application granted granted Critical
Publication of ATE368027T1 publication Critical patent/ATE368027T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT00925490T 1999-04-26 2000-04-26 Bipolare lipide und ihre verwendung zum transport bioaktiver substanzen ATE368027T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9909582.0A GB9909582D0 (en) 1999-04-26 1999-04-26 Chemical compounds
GBGB9924257.0A GB9924257D0 (en) 1999-10-13 1999-10-13 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE368027T1 true ATE368027T1 (de) 2007-08-15

Family

ID=26315471

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00925490T ATE368027T1 (de) 1999-04-26 2000-04-26 Bipolare lipide und ihre verwendung zum transport bioaktiver substanzen

Country Status (6)

Country Link
EP (1) EP1187807B1 (de)
AT (1) ATE368027T1 (de)
AU (1) AU4421200A (de)
DE (1) DE60035687T2 (de)
ES (1) ES2288472T3 (de)
WO (1) WO2000064858A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1829856A3 (de) 1998-11-12 2009-02-25 Invitrogen Corporation Transfektionsreagenzien
GB9919338D0 (en) * 1999-08-16 1999-10-20 Celltech Therapeutics Ltd Biological products
FR2878846B1 (fr) 2004-12-07 2007-02-23 Enscr Composes analogues de lipides membranaires d'archaebacteries et compositions liposomiales integrant de tel composes
WO2016011203A1 (en) 2014-07-15 2016-01-21 Life Technologies Corporation Compositions with lipid aggregates and methods for efficient delivery of molecules to cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2727679B1 (fr) * 1994-12-05 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques
CA2299429C (en) * 1997-08-13 2010-04-20 Biontex Laboratories Gmbh New lipopolyamines,their preparation and the use thereof
AU768542C (en) * 1998-04-08 2004-06-17 Celltech R & D Limited Lipids

Also Published As

Publication number Publication date
DE60035687T2 (de) 2008-06-05
EP1187807A1 (de) 2002-03-20
AU4421200A (en) 2000-11-10
DE60035687D1 (de) 2007-09-06
WO2000064858A1 (en) 2000-11-02
ES2288472T3 (es) 2008-01-16
EP1187807B1 (de) 2007-07-25

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties