NO332275B1 - Fast underlag for immunoanalyse, fremgangsmate for fremstilling derav, fremgangsmater for pavising av hepatitt C virus (HCV) infeksjon i en prove samt immunodiagnostisk testkit. - Google Patents
Fast underlag for immunoanalyse, fremgangsmate for fremstilling derav, fremgangsmater for pavising av hepatitt C virus (HCV) infeksjon i en prove samt immunodiagnostisk testkit. Download PDFInfo
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- NO332275B1 NO332275B1 NO20025878A NO20025878A NO332275B1 NO 332275 B1 NO332275 B1 NO 332275B1 NO 20025878 A NO20025878 A NO 20025878A NO 20025878 A NO20025878 A NO 20025878A NO 332275 B1 NO332275 B1 NO 332275B1
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Classifications
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21208200P | 2000-06-15 | 2000-06-15 | |
| US28081101P | 2001-04-02 | 2001-04-02 | |
| US28086701P | 2001-04-02 | 2001-04-02 | |
| PCT/US2001/019369 WO2001096875A2 (en) | 2000-06-15 | 2001-06-14 | Hcv antigen/antibody combination assay |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20025878D0 NO20025878D0 (no) | 2002-12-06 |
| NO20025878L NO20025878L (no) | 2003-02-12 |
| NO332275B1 true NO332275B1 (no) | 2012-08-13 |
Family
ID=27395684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20025878A NO332275B1 (no) | 2000-06-15 | 2002-12-06 | Fast underlag for immunoanalyse, fremgangsmate for fremstilling derav, fremgangsmater for pavising av hepatitt C virus (HCV) infeksjon i en prove samt immunodiagnostisk testkit. |
Country Status (22)
| Country | Link |
|---|---|
| US (5) | US6632601B2 (de) |
| EP (2) | EP1350105B1 (de) |
| JP (3) | JP4834279B2 (de) |
| CN (3) | CN1214244C (de) |
| AT (2) | ATE368221T1 (de) |
| AU (2) | AU2001272948A1 (de) |
| BG (1) | BG66205B1 (de) |
| BR (2) | BRPI0111731C1 (de) |
| CA (2) | CA2412035C (de) |
| CY (2) | CY1107537T1 (de) |
| CZ (1) | CZ304185B6 (de) |
| DE (2) | DE60125240T3 (de) |
| DK (2) | DK1350105T3 (de) |
| ES (2) | ES2277932T5 (de) |
| HU (1) | HU228873B1 (de) |
| MX (2) | MXPA02012424A (de) |
| NO (1) | NO332275B1 (de) |
| PL (1) | PL213363B1 (de) |
| PT (2) | PT1354204E (de) |
| SI (1) | SI1354204T2 (de) |
| SK (1) | SK287694B6 (de) |
| WO (2) | WO2001096870A2 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69433160T2 (de) * | 1993-05-12 | 2004-07-08 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Konserviertes Motiv der Hepatitis C Virus E2/NS1 Region |
| US7491808B2 (en) * | 2000-06-15 | 2009-02-17 | Novartis Vaccines And Diagnostics, Inc. | HCV non-structural protein mutants and uses thereof |
| SK287694B6 (sk) * | 2000-06-15 | 2011-06-06 | Novartis Vaccines & Diagnostics, Inc. | Pevný nosič imunoeseje a spôsob jeho prípravy, spôsob detekcie infekcie HIV a súprava na imunodiagnostickú skúšku |
| US6858590B2 (en) | 2000-08-17 | 2005-02-22 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| AU2001292151B2 (en) * | 2000-08-17 | 2006-05-04 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| US6680059B2 (en) | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| DE10106295C1 (de) * | 2001-02-02 | 2002-08-22 | Gaifar German American Inst Fo | Protein mit mehreren Antigen-Epitop-Sequenzen, welches immobilisiert ist |
| AU785380B2 (en) * | 2001-03-28 | 2007-03-15 | Ortho-Clinical Diagnostics, Inc. | A hepatitis C antigen - antibody combination assay for the early detection of HCV infection |
| US7101683B2 (en) * | 2001-06-26 | 2006-09-05 | Abbott Laboratories | Methods for the simultaneous detection of HCV antigens and HCV antibodies |
| JP4353793B2 (ja) | 2001-06-26 | 2009-10-28 | アボット・ラボラトリーズ | Hcv抗原とhcv抗体との同時検出のための方法 |
| US7049060B2 (en) * | 2001-11-05 | 2006-05-23 | Ortho-Clinical Diagnostics, Inc. | HCV anti-core monoclonal antibodies |
| US7332269B2 (en) * | 2001-11-11 | 2008-02-19 | Ortho-Clinical Diagnostics, Inc. | HCV core protein sequences |
| FR2839555B1 (fr) | 2002-05-10 | 2007-07-27 | Bio Rad Pasteur | Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux |
| US7166426B2 (en) * | 2002-09-09 | 2007-01-23 | Novartis Vaccines And Diagnostics, Inc. | HCV assay |
| US20040152070A1 (en) * | 2003-02-04 | 2004-08-05 | Shah Dinesh O. | Method of detection of HCV antibodies in combination assay or sole antibody assay |
| EP1668369B1 (de) | 2003-08-20 | 2016-01-06 | ProMIS Neurosciences Inc. | Epitopschutztest und verfahren zum nachweis von proteinkonformationen |
| ATE542140T1 (de) * | 2004-08-27 | 2012-02-15 | Novartis Vaccines & Diagnostic | Nichtstrukturelle hcv-proteinmutanten und verwendungsmöglichkeiten dafür |
| WO2006081701A1 (fr) * | 2005-02-02 | 2006-08-10 | Peng Cui | Kit de detection de l'anticorps du vhc et procede de preparation de celui-ci |
| AU2006335256B2 (en) | 2005-11-22 | 2012-10-18 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and sapovirus antigens |
| US7887803B2 (en) | 2005-12-02 | 2011-02-15 | Amorfix Life Sciences | Methods and compositions to treat misfolded-SOD1 mediated diseases |
| US7794692B2 (en) * | 2005-12-02 | 2010-09-14 | Amorfix Life Sciences Ltd. | Methods and compositions for detecting amyotrophic lateral sclerosis |
| DK2514823T3 (en) | 2006-03-03 | 2018-07-23 | Promis Neurosciences Inc | Methods and compositions for treating and detecting failed SOD1-mediated diseases |
| CN1908666B (zh) * | 2006-08-14 | 2010-05-12 | 武汉大学 | 一种检测乙肝核心抗体的双夹心法酶联免疫诊断试剂盒及应用 |
| WO2009022236A2 (en) | 2007-08-16 | 2009-02-19 | Tripep Ab | Immunogen platform |
| WO2010112733A1 (fr) * | 2009-03-30 | 2010-10-07 | bioMérieux | Support solide de détection du vhc |
| US20100297607A1 (en) * | 2009-05-20 | 2010-11-25 | Jian Zheng | Reagents For HCV Antigen-Antibody Combination Assays |
| JP2013529894A (ja) | 2010-04-07 | 2013-07-25 | ノバルティス アーゲー | パルボウイルスb19のウイルス様粒子を生成するための方法 |
| CN102947703A (zh) * | 2010-06-17 | 2013-02-27 | 皇家飞利浦电子股份有限公司 | 多表位测定 |
| CA2804501C (en) | 2010-07-06 | 2021-01-26 | Novartis Ag | Noro virus derived immunogenic compositions and methods |
| WO2012006500A2 (en) * | 2010-07-08 | 2012-01-12 | Abbott Laboratories | Monoclonal antibodies against hepatitis c virus core protein |
| BR112013017961A2 (pt) * | 2011-01-13 | 2017-07-25 | Ortho Clinical Diagnostics Inc | antígeno tripleto para treponema pallidum |
| FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
| CN105378099B (zh) | 2013-03-14 | 2021-05-11 | 雅培制药有限公司 | Hcv核心脂质结合结构域单克隆抗体 |
| EP2970947A4 (de) | 2013-03-14 | 2016-10-12 | Abbott Lab | Rekombinante hcv-ns3-antigene und mutanten für den verbesserten nachweis von antikörpern |
| JP6505076B2 (ja) | 2013-03-14 | 2019-04-24 | アボット・ラボラトリーズAbbott Laboratories | Hcv抗原−抗体組み合わせアッセイおよびこれに使用するための方法および組成物 |
| CN103630690B (zh) * | 2013-12-17 | 2014-08-20 | 朱之炜 | 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法 |
| EP3274478B1 (de) | 2015-03-27 | 2020-09-23 | Ortho-Clinical Diagnostics, Inc. | Hcv-ns4a/modifizierte ns3-polypeptide und verwendungen davon |
| WO2016172121A1 (en) * | 2015-04-20 | 2016-10-27 | Qoolabs, Inc. | Camelid single-domain hcv antibodies and methods of use |
| EP3688185B1 (de) * | 2017-09-27 | 2023-01-18 | Bio-Rad Laboratories, Inc. | Test für digitale affinitätsverknüpfung |
| CN110261616B (zh) * | 2019-04-30 | 2021-07-20 | 广东菲鹏生物有限公司 | 一种丙型肝炎病毒检测试剂盒 |
| CN115057943B (zh) * | 2022-06-22 | 2025-03-14 | 杭州水芭莎生物医药科技有限公司 | 一种抗菌肽融合蛋白及其制备方法和应用 |
| CN115838420B (zh) * | 2022-10-31 | 2023-05-05 | 北京科跃中楷生物技术有限公司 | 一种可溶性hcv重组蛋白的制备方法及其制备的抗体检测试剂 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2212511B (en) * | 1987-11-18 | 1992-01-22 | Chiron Corp | Hepatitis c virus |
| US5350671A (en) | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
| BR8807310A (pt) * | 1987-11-18 | 1990-03-13 | Chiron Corp | Polinucleotidio,polinucleotidio recombinante,vetor recombinante,celula hospedeira,sistema de expressao recombinante,celula transformada,polipeptidio,hcv,preparacao de polipeptidio,polipeptidio de hcv,polipeptidio purificado,polipeptidio recombinante,polipeptidio de fusao,anticorpo monoclonal,preparacao purificada de anticorpos policlonais,particula,sonda de polinucleotidio,kit anticorpo para epetopo de hcv,metodo para producao de polipeptidio,metodo para deteccao de acidos nucleicos de hcv,imunoensaio para detectar antigeno de hcv,imunoensaio para detectar anticorpos dirigidos contra antigeno de hcv,vacina para tratamento de infeccao de hcv,celula,celula infectada com hcv,metodo para producao de anticorpos para hcv e metodo para isolar cdna derivado do genoma de um agente infeccioso nao identificado |
| US6171782B1 (en) | 1987-11-18 | 2001-01-09 | Chiron Corporation | Antibody compositions to HCV and uses thereof |
| US5683864A (en) * | 1987-11-18 | 1997-11-04 | Chiron Corporation | Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
| JP2730153B2 (ja) | 1989-03-16 | 1998-03-25 | 日本合成ゴム株式会社 | 熱可塑性樹脂組成物およびその製造方法 |
| HU225068B1 (en) | 1989-03-17 | 2006-05-29 | Chiron Corp | Process for producing diagnostics and vaccine of nanbh |
| JP2656996B2 (ja) * | 1989-05-18 | 1997-09-24 | カイロン コーポレイション | Nanbvの診断用薬 |
| US6194140B1 (en) * | 1990-04-04 | 2001-02-27 | Chiron Corporation | HCV NS3 protein fragments having helicase activity and improved solubility |
| US5712087A (en) | 1990-04-04 | 1998-01-27 | Chiron Corporation | Immunoassays for anti-HCV antibodies employing combinations of hepatitis C virus (HCV) antigens |
| WO1991015771A1 (en) * | 1990-04-04 | 1991-10-17 | Chiron Corporation | Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies |
| CA2049679C (en) * | 1990-08-24 | 2005-06-21 | Sushil G. Devare | Hepatitis c assay utilizing recombinant antigens |
| PT97247B (pt) * | 1991-04-03 | 1997-10-31 | Chiron Corp | Processo de preparacao de combinacoes de antigenios do virus da hepapite c (hcv) para uso em imunoensaios para anticorpos anti-hcv |
| KR0185426B1 (ko) | 1991-06-24 | 1999-04-01 | 로버트 피. 블랙버언 | 씨형 간염 바이러스 폴리펩티드 |
| UA39944C2 (uk) | 1992-07-07 | 2001-07-16 | Чірон Корпорейшн | Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі |
| ATE551423T1 (de) * | 1993-04-27 | 2012-04-15 | Innogenetics Nv | Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika |
| US6001604A (en) * | 1993-12-29 | 1999-12-14 | Bio-Technology General Corp. | Refolding of proinsulins without addition of reducing agents |
| JP3217600B2 (ja) | 1994-07-12 | 2001-10-09 | 株式会社先端生命科学研究所 | 非a非b型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ |
| DE4428705A1 (de) * | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
| US5843752A (en) | 1995-05-12 | 1998-12-01 | Schering Corporation | Soluble active hepatitis C virus protease |
| US5990276A (en) | 1996-05-10 | 1999-11-23 | Schering Corporation | Synthetic inhibitors of hepatitis C virus NS3 protease |
| US6514731B1 (en) * | 1996-05-24 | 2003-02-04 | Chiron Corporation | Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens |
| JP3945822B2 (ja) | 1996-05-24 | 2007-07-18 | カイロン コーポレイション | 複数エピトープ融合タンパク質 |
| EP0870830A3 (de) * | 1997-02-10 | 2004-02-25 | Advanced Life Science Institute, Inc. | Chimäres Hepatitis C-Virusantigen |
| PT1021719E (pt) * | 1997-09-22 | 2007-03-30 | Novartis Vaccines & Diagnostic | Método para detecção de anticorpos numa amostra |
| JP3514729B2 (ja) * | 1998-07-30 | 2004-03-31 | 株式会社先端生命科学研究所 | C型肝炎ウイルスの測定方法 |
| SK287694B6 (sk) * | 2000-06-15 | 2011-06-06 | Novartis Vaccines & Diagnostics, Inc. | Pevný nosič imunoeseje a spôsob jeho prípravy, spôsob detekcie infekcie HIV a súprava na imunodiagnostickú skúšku |
-
2001
- 2001-06-14 SK SK1777-2002A patent/SK287694B6/sk not_active IP Right Cessation
- 2001-06-14 PL PL365599A patent/PL213363B1/pl not_active IP Right Cessation
- 2001-06-14 CA CA2412035A patent/CA2412035C/en not_active Expired - Lifetime
- 2001-06-14 WO PCT/US2001/019156 patent/WO2001096870A2/en not_active Ceased
- 2001-06-14 SI SI200130682T patent/SI1354204T2/sl unknown
- 2001-06-14 AU AU2001272948A patent/AU2001272948A1/en not_active Abandoned
- 2001-06-14 DE DE60125240T patent/DE60125240T3/de not_active Expired - Lifetime
- 2001-06-14 WO PCT/US2001/019369 patent/WO2001096875A2/en not_active Ceased
- 2001-06-14 EP EP01952156A patent/EP1350105B1/de not_active Expired - Lifetime
- 2001-06-14 US US09/881,654 patent/US6632601B2/en not_active Expired - Lifetime
- 2001-06-14 MX MXPA02012424A patent/MXPA02012424A/es active IP Right Grant
- 2001-06-14 AT AT01952156T patent/ATE368221T1/de active
- 2001-06-14 JP JP2002510953A patent/JP4834279B2/ja not_active Expired - Lifetime
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- 2001-06-14 HU HU0500444A patent/HU228873B1/hu unknown
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- 2001-06-14 EP EP01952160A patent/EP1354204B2/de not_active Expired - Lifetime
- 2001-06-14 AT AT01952160T patent/ATE348337T1/de active
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- 2001-06-14 CN CNB2004100116606A patent/CN100463922C/zh not_active Expired - Lifetime
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- 2001-06-14 CA CA2413003A patent/CA2413003C/en not_active Expired - Lifetime
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- 2001-06-14 DK DK01952156T patent/DK1350105T3/da active
- 2001-06-14 AU AU2001272945A patent/AU2001272945A1/en not_active Abandoned
- 2001-06-14 DK DK01952160.8T patent/DK1354204T4/da active
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2002
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2003
- 2003-01-07 BG BG107441A patent/BG66205B1/bg unknown
- 2003-08-08 US US10/637,323 patent/US6797809B2/en not_active Expired - Lifetime
- 2003-08-19 US US10/643,853 patent/US7319144B2/en not_active Expired - Lifetime
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2004
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2007
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Owner name: GRIFOLS WORDWIDE OPERATIONS LIMITED, IE |
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| CREP | Change of representative |
Representative=s name: BRYN AARFLOT AS, POSTBOKS 449 SENTRUM, 0104 OSLO |
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| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: GRIFOLS WORLDWIDE OPERATIONS LIMITED, IE |
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| MK1K | Patent expired |