ATE37984T1 - Pharmazeutische zusammensetzung welche 5acetamido-3,5-dideoxy-d-glycero-dgalactononulosamins|ure cytidin monophosphat enthaelt. - Google Patents
Pharmazeutische zusammensetzung welche 5acetamido-3,5-dideoxy-d-glycero-dgalactononulosamins|ure cytidin monophosphat enthaelt.Info
- Publication number
- ATE37984T1 ATE37984T1 AT84102059T AT84102059T ATE37984T1 AT E37984 T1 ATE37984 T1 AT E37984T1 AT 84102059 T AT84102059 T AT 84102059T AT 84102059 T AT84102059 T AT 84102059T AT E37984 T1 ATE37984 T1 AT E37984T1
- Authority
- AT
- Austria
- Prior art keywords
- glycero
- dideoxy
- dgalactononulosamine
- 5acetamido
- ure
- Prior art date
Links
- -1 URE CYTIDIN MONOPHOSPHATE Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- PCDQPRRSZKQHHS-CCXZUQQUSA-N Cytarabine Triphosphate Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1 PCDQPRRSZKQHHS-CCXZUQQUSA-N 0.000 abstract 2
- SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 abstract 2
- IERHLVCPSMICTF-XVFCMESISA-N cytidine 5'-monophosphate Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O1 IERHLVCPSMICTF-XVFCMESISA-N 0.000 abstract 2
- IERHLVCPSMICTF-UHFFFAOYSA-N cytidine monophosphate Natural products O=C1N=C(N)C=CN1C1C(O)C(O)C(COP(O)(O)=O)O1 IERHLVCPSMICTF-UHFFFAOYSA-N 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/305—Pyrimidine nucleotides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT83341/83A IT1175061B (it) | 1983-03-01 | 1983-03-01 | Applicazione terapeutica del citidin monofosfato dell'acido 5-acetamido-3,5-dideossi-d-glicero-d-galattononulo saminico |
| IT83371/83A IT1175084B (it) | 1983-04-20 | 1983-04-20 | Metodo per la preparazione del citidin monofosfato dell'acido 5-acetamido-3,5-dideossi-d-glicero-d-galattononulo-saminico |
| EP84102059A EP0120328B1 (de) | 1983-03-01 | 1984-02-28 | Pharmazeutische Zusammensetzung welche 5-Acetamido-3,5-Dideoxy-D-Glycero-D-Galactononulosaminsäure Cytidin Monophosphat enthält |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE37984T1 true ATE37984T1 (de) | 1988-11-15 |
Family
ID=26330056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84102059T ATE37984T1 (de) | 1983-03-01 | 1984-02-28 | Pharmazeutische zusammensetzung welche 5acetamido-3,5-dideoxy-d-glycero-dgalactononulosamins|ure cytidin monophosphat enthaelt. |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US4704361A (de) |
| EP (2) | EP0120328B1 (de) |
| JP (1) | JPH0276894A (de) |
| AT (1) | ATE37984T1 (de) |
| CA (1) | CA1219539A (de) |
| DE (1) | DE3474632D1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61204190A (ja) * | 1985-03-06 | 1986-09-10 | Kanto Ishi Pharma Co Ltd | グリコシド及びその製造方法 |
| EP0408668B1 (de) * | 1988-10-27 | 1994-05-11 | Massachusetts Institute Of Technology | Verfahren zur Steigerung des Phosphatidylcholins in Vivo |
| US5109126A (en) * | 1988-12-06 | 1992-04-28 | Worcester Foundation For Experimental Biology | 5'[2'(3')-O-(2,4,6-trinitrophenyl) pyprimidine nucleoside]diphosphate 1-glycosides |
| US5059535A (en) * | 1989-04-12 | 1991-10-22 | Chembiomed, Ltd. | Process for the separation and purification of sialyl transferases |
| DK0524143T3 (da) * | 1991-07-17 | 1998-08-24 | Novartis Ag | Fremgangsmåde til fremstilling af aktiverede sialinsyrer |
| ATE174925T1 (de) * | 1991-10-15 | 1999-01-15 | Scripps Research Inst | Herstellung von fucosylierten kohlenhydraten durch enzymatische fucosylierungs-synthese der zuckernukleotide; und in situ regeneration von gdp-fucose |
| JPH0967270A (ja) * | 1995-08-31 | 1997-03-11 | Res Dev Corp Of Japan | 水晶体混濁の予防および治療法、並びにそのための薬 剤 |
| US5958896A (en) * | 1997-08-08 | 1999-09-28 | The Mclean Hospital | Cytidine-containing and cytosine-containing compounds as treatments for stimulant exposure |
| WO2001068104A1 (en) * | 2000-03-16 | 2001-09-20 | The Mclean Hospital Corporation | Compounds for the treatment of psychiatric or substance abuse disorders |
| PT1565055E (pt) * | 2002-11-08 | 2013-09-16 | Mclean Hospital Corp | Compostos para o tratamento da dependência e da privação de tabaco |
| US20050038343A1 (en) * | 2003-07-10 | 2005-02-17 | Alfred E. Mann Institute For Biomedical Research At The University Of Southern California | Apparatus and method for locating a bifurcation in an artery |
| WO2005034874A2 (en) * | 2003-10-08 | 2005-04-21 | The Mclean Hospital Corporation | Enhanced efficacy of omega-3 fatty acid therapy in the treatment of psychiatric disorders and other indications |
| JP2007508315A (ja) * | 2003-10-08 | 2007-04-05 | ザ マクレーン ホスピタル コーポレーション | ω−3脂肪酸を含む組み合わせを用いて、精神障害、物質乱用障害、および他の障害を治療する方法 |
| WO2005122767A1 (en) * | 2004-06-10 | 2005-12-29 | Mclean Hospital Corporation | Pyrimidines, such as uridine, in treatments for patients with bipolar disorder |
| EP1765364A4 (de) * | 2004-06-10 | 2010-09-22 | Mclean Hospital Corp | Pyrimidine, wie z:b: cytidin, bei der behandlung von patienten mit bipolaren störungen |
| US7947661B2 (en) * | 2004-08-11 | 2011-05-24 | The Mclean Hospital Corporation | Compounds for the treatment of marihuana dependence, withdrawal, and usage |
| EP1814573B1 (de) | 2004-10-29 | 2016-03-09 | ratiopharm GmbH | Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf) |
| CA2593682C (en) | 2005-01-10 | 2016-03-22 | Neose Technologies, Inc. | Glycopegylated granulocyte colony stimulating factor |
| CN101516388B (zh) | 2006-07-21 | 2012-10-31 | 诺和诺德公司 | 通过o-联糖基化序列的肽的糖基化 |
| US8969532B2 (en) | 2006-10-03 | 2015-03-03 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography |
| EP2144923B1 (de) | 2007-04-03 | 2013-02-13 | BioGeneriX AG | Behandlungsverfahren mit glycopegyliertem g-csf |
| WO2008154639A2 (en) * | 2007-06-12 | 2008-12-18 | Neose Technologies, Inc. | Improved process for the production of nucleotide sugars |
| US20130189239A1 (en) | 2008-02-27 | 2013-07-25 | Novo Nordisk A/S | Conjugated Factor VIII Molecules |
| US20100041621A1 (en) * | 2008-08-15 | 2010-02-18 | Perry Renshaw | Methods and compositions for improving cognitive performance |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4100271A (en) * | 1976-02-26 | 1978-07-11 | Cooper Laboratories, Inc. | Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes |
| DE2648759C3 (de) * | 1976-10-27 | 1979-05-31 | Boehringer Mannheim Gmbh, 6800 Mannheim | Stabilisierungsmittel für Enzyme |
| US4593091A (en) * | 1981-08-04 | 1986-06-03 | Fidia, S.P.A. | Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions |
-
1984
- 1984-02-28 AT AT84102059T patent/ATE37984T1/de not_active IP Right Cessation
- 1984-02-28 DE DE8484102059T patent/DE3474632D1/de not_active Expired
- 1984-02-28 EP EP84102059A patent/EP0120328B1/de not_active Expired
- 1984-02-28 EP EP87114882A patent/EP0263533A3/de not_active Withdrawn
- 1984-02-29 CA CA000448517A patent/CA1219539A/en not_active Expired
- 1984-02-29 US US06/584,805 patent/US4704361A/en not_active Expired - Fee Related
-
1989
- 1989-08-23 JP JP1215137A patent/JPH0276894A/ja active Pending
-
1990
- 1990-07-23 US US07/560,239 patent/US5070079A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5070079A (en) | 1991-12-03 |
| JPH0276894A (ja) | 1990-03-16 |
| US4704361A (en) | 1987-11-03 |
| CA1219539A (en) | 1987-03-24 |
| EP0120328A2 (de) | 1984-10-03 |
| DE3474632D1 (en) | 1988-11-24 |
| EP0120328B1 (de) | 1988-10-19 |
| EP0263533A2 (de) | 1988-04-13 |
| EP0263533A3 (de) | 1990-05-30 |
| EP0120328A3 (en) | 1985-01-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |