ATE383420T1 - Verwendung des cyp52a2a promotors für die erhöhung der genexpression in hefe - Google Patents

Verwendung des cyp52a2a promotors für die erhöhung der genexpression in hefe

Info

Publication number
ATE383420T1
ATE383420T1 AT01953603T AT01953603T ATE383420T1 AT E383420 T1 ATE383420 T1 AT E383420T1 AT 01953603 T AT01953603 T AT 01953603T AT 01953603 T AT01953603 T AT 01953603T AT E383420 T1 ATE383420 T1 AT E383420T1
Authority
AT
Austria
Prior art keywords
nucleic acid
yeast
gene expression
increase gene
acid sequence
Prior art date
Application number
AT01953603T
Other languages
English (en)
Inventor
David Craft
C Wilson
Dudley Eirich
Yeyan Zhang
Original Assignee
Cognis Ip Man Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cognis Ip Man Gmbh filed Critical Cognis Ip Man Gmbh
Application granted granted Critical
Publication of ATE383420T1 publication Critical patent/ATE383420T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT01953603T 2000-07-26 2001-07-25 Verwendung des cyp52a2a promotors für die erhöhung der genexpression in hefe ATE383420T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22085000P 2000-07-26 2000-07-26
US09/911,781 US6673613B2 (en) 2000-07-26 2001-07-24 Use of CYP52A2A promoter to increase gene expression in yeast

Publications (1)

Publication Number Publication Date
ATE383420T1 true ATE383420T1 (de) 2008-01-15

Family

ID=26915242

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01953603T ATE383420T1 (de) 2000-07-26 2001-07-25 Verwendung des cyp52a2a promotors für die erhöhung der genexpression in hefe

Country Status (8)

Country Link
US (2) US6673613B2 (de)
EP (1) EP1303593B1 (de)
CN (1) CN1444649A (de)
AT (1) ATE383420T1 (de)
AU (1) AU2001276036A1 (de)
DE (1) DE60132332T2 (de)
DK (1) DK1303593T3 (de)
WO (1) WO2002008412A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002344369A1 (en) * 2001-06-01 2002-12-16 Epidauros Biotechnologie Ag Polymorphisms in the human gene for cytochrome p450 polypeptide 2c8 and their use in diagnostic and therapeutic applications
EP1506302A4 (de) * 2002-05-23 2006-02-08 Cognis Ip Man Gmbh Nichtrevertierbare beta-oxidationsblockierte candida tropicalis
US7388084B2 (en) * 2002-08-16 2008-06-17 Cognis Corporation Promoter motifs in Candida tropicalis
FR2879215B1 (fr) * 2004-12-15 2010-08-20 Inst Francais Du Petrole Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica
KR20100053598A (ko) * 2007-08-01 2010-05-20 이데라 파마슈티칼즈, 인코포레이티드 Ｔｌｒ９의 신규한 합성 효능제
US8597931B2 (en) * 2008-07-11 2013-12-03 Institut National De La Recherche Agronomique (Inra) Mutant yeast strains capable of accumulating a large quantity of lipids
US20120156761A1 (en) 2009-07-02 2012-06-21 Verdezyne, Inc. Biological methods for preparing adipic acid
WO2012071439A1 (en) * 2010-11-22 2012-05-31 The Regents Of The University Of California Host cells and methods for producing diacid compounds
CN102212546B (zh) * 2011-02-28 2013-04-17 福建福大百特科技发展有限公司 一种整合型麦芽糖假丝酵母基因表达系统及其应用
US8735094B2 (en) 2011-04-05 2014-05-27 E I Du Pont De Nemours And Company Yarrowia n-alkane-hydroxylating cytochrome P450 promoter regions for gene expression in yeast
US8728798B2 (en) 2011-05-03 2014-05-20 Verdezyne, Inc. Biological methods for preparing adipic acid
US8343752B2 (en) 2011-05-03 2013-01-01 Verdezyne, Inc. Biological methods for preparing adipic acid
CA3051939C (en) 2011-07-06 2023-08-01 Verdezyne, Inc. Genetically modified yeast with increased alcohol dehydrogenase activity for preparing a fatty dicarboxylic acid
CN103992959B (zh) * 2014-04-28 2017-02-08 中国科学院微生物研究所 长链二元酸生产菌株及其制备方法和应用
CN110684783B (zh) * 2018-07-06 2023-08-08 上海凯赛生物技术股份有限公司 一种低含量脂肪酸杂质的长链二元酸及其生产方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254466A (en) 1989-11-06 1993-10-19 Henkel Research Corporation Site-specific modification of the candida tropicals genome
GB9703406D0 (en) * 1997-02-19 1997-04-09 Chiron Spa Expression of heterologous proteins
US6331420B1 (en) 1998-05-01 2001-12-18 C. Ron Wilson Cytochrome P450 monooxygenase and NADPH cytochrome P450 oxidoreductase genes and proteins related to the omega hydroxylase complex of Candida tropicalis and methods relating thereto
EP1135506B1 (de) 1998-10-05 2005-04-20 Cognis Corporation Cytochrom p450 monooxygenase und nadph-cytochrom p450-oxidoreduktase gene und proteine mit bezug zum omega-hydroxylase-komplex in candida tropicalis und dazu gehörigen verfahren

Also Published As

Publication number Publication date
US20030175896A1 (en) 2003-09-18
EP1303593A2 (de) 2003-04-23
EP1303593B1 (de) 2008-01-09
AU2001276036A1 (en) 2002-02-05
US6673613B2 (en) 2004-01-06
WO2002008412A3 (en) 2002-05-30
DK1303593T3 (da) 2008-05-19
CN1444649A (zh) 2003-09-24
WO2002008412A2 (en) 2002-01-31
US6790640B2 (en) 2004-09-14
DE60132332T2 (de) 2009-01-02
US20020034788A1 (en) 2002-03-21
DE60132332D1 (de) 2008-02-21

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