ATE384079T1 - Marker für stammzellen und dessen verwendung - Google Patents
Marker für stammzellen und dessen verwendungInfo
- Publication number
- ATE384079T1 ATE384079T1 AT03733733T AT03733733T ATE384079T1 AT E384079 T1 ATE384079 T1 AT E384079T1 AT 03733733 T AT03733733 T AT 03733733T AT 03733733 T AT03733733 T AT 03733733T AT E384079 T1 ATE384079 T1 AT E384079T1
- Authority
- AT
- Austria
- Prior art keywords
- msc
- stem cells
- marker
- markers
- mammalian
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 title 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 abstract 7
- 239000003550 marker Substances 0.000 abstract 3
- 230000001413 cellular effect Effects 0.000 abstract 2
- 238000002955 isolation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102100025310 Integrin alpha-10 Human genes 0.000 abstract 1
- 102100025320 Integrin alpha-11 Human genes 0.000 abstract 1
- 101710123196 Integrin alpha-11 Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 108010035006 integrin alpha 10 Proteins 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
- C07K14/7055—Integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70546—Integrin superfamily, e.g. VLAs, leuCAM, GPIIb/GPIIIa, LPAM
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Developmental Biology & Embryology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38829802P | 2002-06-14 | 2002-06-14 | |
| SE0201831A SE0201831D0 (sv) | 2002-06-14 | 2002-06-14 | Marker for stem cells and its use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE384079T1 true ATE384079T1 (de) | 2008-02-15 |
Family
ID=29738561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03733733T ATE384079T1 (de) | 2002-06-14 | 2003-06-12 | Marker für stammzellen und dessen verwendung |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7749710B2 (de) |
| EP (2) | EP1513877B1 (de) |
| JP (1) | JP4399533B2 (de) |
| AT (1) | ATE384079T1 (de) |
| AU (1) | AU2003239016B2 (de) |
| CA (1) | CA2489212C (de) |
| DE (1) | DE60318706T2 (de) |
| DK (1) | DK1513877T3 (de) |
| ES (1) | ES2306876T3 (de) |
| WO (1) | WO2003106492A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1068238T3 (da) | 1998-04-02 | 2013-01-14 | Xintela Ab | Integrinheterodimer og subunit deraf |
| JP5064025B2 (ja) * | 2003-04-14 | 2012-10-31 | キシンテラ、アクチボラグ | インテグリンα１０β１を結合することができる新規モノクローナル抗体 |
| SE0301087D0 (sv) | 2003-04-14 | 2003-04-14 | Cartela Ab | New monoclonal antibody |
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| ES2313805B1 (es) * | 2004-10-04 | 2009-12-23 | Cellerix, S.L. | Identificacion y aislamiento de celulas multipotentes de tejido mesenquimal no osteocondral. |
| US9234897B2 (en) | 2005-03-31 | 2016-01-12 | Two Cells Co., Ltd | Method for distinguishing mesenchymal stem cell using molecular marker and use thereof |
| SG10202001007TA (en) | 2005-09-23 | 2020-03-30 | Tigenix Sau | Cell populations having immunoregulatory activity, method for isolation and uses |
| DE102006026191A1 (de) * | 2006-05-26 | 2007-11-29 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Vorrichtung und Substanz zur Isolierung von mesenchymalen Stammzellen (MSC) |
| WO2008099561A1 (ja) * | 2007-02-14 | 2008-08-21 | Japan Science And Technology Agency | 抗菌性ペプチドを用いた細胞増殖促進剤及び該細胞増殖促進剤を含有する無血清培地を用いる細胞増殖促進方法 |
| WO2009128533A1 (ja) * | 2008-04-18 | 2009-10-22 | 国立大学法人名古屋大学 | 間葉系幹細胞およびその生産方法 |
| KR101158473B1 (ko) * | 2009-01-15 | 2012-06-20 | 코아스템(주) | 연골줄기세포를 유효성분으로 포함하는 골질환 치료용 또는 항염증용 약제학적 조성물 |
| WO2016006788A1 (ko) * | 2014-07-07 | 2016-01-14 | 메디포스트(주) | 작은 크기 줄기세포의 발모 촉진능 및 이의 용도 |
| ES2850048T3 (es) | 2015-02-16 | 2021-08-25 | Xintela Ab | Detección y tratamiento de tumores malignos en el SNC |
| GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| IL264342B2 (en) * | 2016-08-17 | 2024-04-01 | Xintela Ab | A marker for neural stem cells |
| KR102580320B1 (ko) * | 2017-01-27 | 2023-09-19 | 신텔라 에이비 | 골 및 연골 손상 또는 질환의 예방 및 치료 |
| WO2019102268A1 (en) * | 2017-11-22 | 2019-05-31 | Mesoblast International Sarl | Cellular compositions and methods of treatment i |
| BR112023023975A2 (pt) * | 2021-05-20 | 2024-01-30 | Xintela Ab | Composição, método para regeneração da pele, uso de uma composição cosmética, e, método para tratar um defeito de pele |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5837539A (en) * | 1990-11-16 | 1998-11-17 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human mesenchymal stem cells |
| US6200606B1 (en) | 1996-01-16 | 2001-03-13 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration |
| AU5436998A (en) | 1996-11-15 | 1998-06-03 | Osiris Therapeutics, Inc. | MSC-megakaryocyte precursor composition and method of isolating MSCs asso ciated with isolated megakaryocytes by isolating megakaryocytes |
| DK1068238T3 (da) | 1998-04-02 | 2013-01-14 | Xintela Ab | Integrinheterodimer og subunit deraf |
| SE9902056D0 (sv) * | 1999-06-03 | 1999-06-03 | Active Biotech Ab | An integrin heterodimer and an alpha subunit thereof |
| JP2006510576A (ja) * | 2002-06-17 | 2006-03-30 | カルテラ、アクチボラグ | アテローム性動脈硬化症のプラーク形成の進行を防止するためのインテグリンα１０鎖の方法および使用 |
| US20090232777A1 (en) * | 2006-03-01 | 2009-09-17 | Evy Lundgren-Akerlund | Expansion and Differentiation of Mesenchymal Stem Cells |
-
2003
- 2003-06-12 AU AU2003239016A patent/AU2003239016B2/en not_active Expired
- 2003-06-12 DE DE60318706T patent/DE60318706T2/de not_active Expired - Lifetime
- 2003-06-12 EP EP03733733A patent/EP1513877B1/de not_active Expired - Lifetime
- 2003-06-12 AT AT03733733T patent/ATE384079T1/de active
- 2003-06-12 WO PCT/SE2003/000983 patent/WO2003106492A1/en not_active Ceased
- 2003-06-12 ES ES03733733T patent/ES2306876T3/es not_active Expired - Lifetime
- 2003-06-12 CA CA2489212A patent/CA2489212C/en not_active Expired - Lifetime
- 2003-06-12 JP JP2004513323A patent/JP4399533B2/ja not_active Expired - Lifetime
- 2003-06-12 EP EP07023659A patent/EP1990350A1/de not_active Withdrawn
- 2003-06-12 US US10/517,210 patent/US7749710B2/en not_active Expired - Lifetime
- 2003-06-12 DK DK03733733T patent/DK1513877T3/da active
-
2010
- 2010-05-25 US US12/787,224 patent/US8105791B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1513877B1 (de) | 2008-01-16 |
| DK1513877T3 (da) | 2008-06-02 |
| DE60318706T2 (de) | 2009-04-30 |
| ES2306876T3 (es) | 2008-11-16 |
| DE60318706D1 (de) | 2008-03-06 |
| US8105791B2 (en) | 2012-01-31 |
| JP4399533B2 (ja) | 2010-01-20 |
| CA2489212A1 (en) | 2003-12-24 |
| US20110033923A1 (en) | 2011-02-10 |
| EP1990350A1 (de) | 2008-11-12 |
| CA2489212C (en) | 2012-08-14 |
| AU2003239016B2 (en) | 2007-09-20 |
| WO2003106492A1 (en) | 2003-12-24 |
| JP2006511201A (ja) | 2006-04-06 |
| US20050221327A1 (en) | 2005-10-06 |
| WO2003106492A8 (en) | 2005-05-19 |
| US7749710B2 (en) | 2010-07-06 |
| AU2003239016A1 (en) | 2003-12-31 |
| EP1513877A1 (de) | 2005-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner | ||
| UEP | Publication of translation of european patent specification |
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