ATE386727T1 - Kondensierte pyrimidine als antagonisten des corticotropin releasing factor (crf) - Google Patents

Kondensierte pyrimidine als antagonisten des corticotropin releasing factor (crf)

Info

Publication number
ATE386727T1
ATE386727T1 AT02722478T AT02722478T ATE386727T1 AT E386727 T1 ATE386727 T1 AT E386727T1 AT 02722478 T AT02722478 T AT 02722478T AT 02722478 T AT02722478 T AT 02722478T AT E386727 T1 ATE386727 T1 AT E386727T1
Authority
AT
Austria
Prior art keywords
crf
antagonists
releasing factor
corticotropin releasing
condensed pyrimidines
Prior art date
Application number
AT02722478T
Other languages
English (en)
Inventor
Anna Maria Capelli
Chiara Marchionni
Fabrizio Micheli
Alessandra Pasquarello
Benedetta Perini
Yves St-Denis
Fabio Romano Di
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0110567A external-priority patent/GB0110567D0/en
Priority claimed from GB0110569A external-priority patent/GB0110569D0/en
Priority claimed from GB0110570A external-priority patent/GB0110570D0/en
Priority claimed from GB0117420A external-priority patent/GB0117420D0/en
Priority claimed from GB0117399A external-priority patent/GB0117399D0/en
Priority claimed from GB0117401A external-priority patent/GB0117401D0/en
Priority claimed from GB0203201A external-priority patent/GB0203201D0/en
Priority claimed from GB0206834A external-priority patent/GB0206834D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE386727T1 publication Critical patent/ATE386727T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
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    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0463—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
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    • A61K51/0465—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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AT02722478T 2001-04-30 2002-04-30 Kondensierte pyrimidine als antagonisten des corticotropin releasing factor (crf) ATE386727T1 (de)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB0110567A GB0110567D0 (en) 2001-04-30 2001-04-30 Chemical compounds
GB0110569A GB0110569D0 (en) 2001-04-30 2001-04-30 Chemical compounds
GB0110570A GB0110570D0 (en) 2001-04-30 2001-04-30 Chemical compounds
GB0117420A GB0117420D0 (en) 2001-07-17 2001-07-17 Chemical compounds
GB0117399A GB0117399D0 (en) 2001-07-17 2001-07-17 Chemical compounds
GB0117401A GB0117401D0 (en) 2001-07-17 2001-07-17 Chemical compounds
GB0203201A GB0203201D0 (en) 2002-02-11 2002-02-11 Chemical compounds
GB0206834A GB0206834D0 (en) 2002-03-22 2002-03-22 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE386727T1 true ATE386727T1 (de) 2008-03-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AT02722478T ATE386727T1 (de) 2001-04-30 2002-04-30 Kondensierte pyrimidine als antagonisten des corticotropin releasing factor (crf)

Country Status (19)

Country Link
US (1) US7279474B2 (de)
EP (1) EP1383747B1 (de)
JP (1) JP2004528349A (de)
KR (1) KR20040015206A (de)
CN (1) CN1649848A (de)
AR (1) AR033295A1 (de)
AT (1) ATE386727T1 (de)
AU (1) AU2002253357B2 (de)
BR (1) BR0209267A (de)
CA (1) CA2446514A1 (de)
CZ (1) CZ20032946A3 (de)
DE (1) DE60225127T2 (de)
ES (1) ES2301633T3 (de)
HU (1) HUP0304054A2 (de)
IL (1) IL158062A0 (de)
MX (1) MXPA03009938A (de)
NO (1) NO20034836L (de)
PL (1) PL366934A1 (de)
WO (1) WO2002088095A1 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE397609T1 (de) * 2001-06-12 2008-06-15 Glaxo Group Ltd Corticotropinfreisetzungsfaktor antagonisten
GB0117396D0 (en) * 2001-07-17 2001-09-05 Glaxo Group Ltd Chemical compounds
EP1583531B1 (de) * 2003-01-16 2007-04-18 SB Pharmco Puerto Rico Inc Heteroaryl-substituierte pyrrol[2, 3- b]pyridin-derivate als crf-rezeptor-antagonisten
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