ATE386729T1 - Cyclothiocarbamatderivate als progesteron- rezeptormodulatoren - Google Patents

Cyclothiocarbamatderivate als progesteron- rezeptormodulatoren

Info

Publication number: ATE386729T1
Authority: AT; Austria
Prior art keywords: alkyl; optionally substituted; aryl; ring; groups
Prior art date: 1999-05-04

Application number

AT00930266T

Other languages

English (en)

Inventor

Puwen Zhang

Andrew Fensome

Eugene Terefenko

Lin Zhi

Todd Jones

Mark Collins

Christopher Tegley

Jay Wrobel

James Edwards

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-04

Filing date

2000-05-01

Publication date

2008-03-15

2000-04-19 Priority claimed from US09/552,354 external-priority patent/US6436929B1/en

2000-05-01 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-03-15 Application granted granted Critical

2008-03-15 Publication of ATE386729T1 publication Critical patent/ATE386729T1/de

Links

239000002379 progesterone receptor modulator Substances 0.000 title 1
229940095745 sex hormone and modulator of the genital system progesterone receptor modulator Drugs 0.000 title 1
RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 4
125000003118 aryl group Chemical group 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000004103 aminoalkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004122 cyclic group Chemical group 0.000 abstract 2
125000005842 heteroatom Chemical group 0.000 abstract 2
125000000623 heterocyclic group Chemical group 0.000 abstract 2
125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 2
229960003387 progesterone Drugs 0.000 abstract 2
239000000186 progesterone Substances 0.000 abstract 2
125000003003 spiro group Chemical group 0.000 abstract 2
125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
241000689227 Cora <basidiomycete fungus> Species 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Chemical Or Physical Treatment Of Fibers (AREA)
Detergent Compositions (AREA)
Steroid Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT00930266T 1999-05-04 2000-05-01 Cyclothiocarbamatderivate als progesteron- rezeptormodulatoren ATE386729T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US18301399P	1999-05-04	1999-05-04
US09/552,354 US6436929B1 (en)	1999-05-04	2000-04-19	Cyclothiocarbamate derivatives as progesterone receptor modulators

Publications (1)

Publication Number	Publication Date
ATE386729T1 true ATE386729T1 (de)	2008-03-15

Family

ID=26878649

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00930266T ATE386729T1 (de)	1999-05-04	2000-05-01	Cyclothiocarbamatderivate als progesteron- rezeptormodulatoren

Country Status (24)

Country	Link
EP (1)	EP1175411B1 (de)
JP (2)	JP4958338B2 (de)
KR (1)	KR100732692B1 (de)
CN (1)	CN1131856C (de)
AT (1)	ATE386729T1 (de)
AU (1)	AU766801B2 (de)
BG (1)	BG65277B1 (de)
BR (1)	BR0010214A (de)
CA (1)	CA2371712C (de)
CZ (1)	CZ20013952A3 (de)
DE (1)	DE60038108T2 (de)
DK (1)	DK1175411T3 (de)
EA (1)	EA004511B1 (de)
ES (1)	ES2301482T3 (de)
GE (1)	GEP20043181B (de)
HU (1)	HUP0203332A3 (de)
IL (1)	IL146298A0 (de)
MX (1)	MXPA01011287A (de)
NO (1)	NO321370B1 (de)
NZ (1)	NZ515353A (de)
PL (1)	PL351083A1 (de)
SG (1)	SG120970A1 (de)
SK (1)	SK15922001A3 (de)
TR (1)	TR200103285T2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6407101B1 (en) *	1999-05-04	2002-06-18	American Home Products Corporation	Cyanopyrroles
MXPA01011287A (es) *	1999-05-04	2003-07-14	American Home Prod	Derivados de ciclotiocarbamato como moduladores de receptor de progesterona.
DK1732922T3 (da) *	2004-04-08	2009-01-12	Wyeth Corp	Fremgangsmåde til minimering af thioamidurenheder
ATE413398T1 (de) *	2004-04-08	2008-11-15	Wyeth Corp	Thioamidderivate als progesteronrezeptormodulatoren
WO2005104711A2 (en) *	2004-04-27	2005-11-10	Wyeth	Purification of progesterone receptor modulators
ATE396189T1 (de) *	2004-04-27	2008-06-15	Wyeth Corp	Cyanopyrrolhaltige cyclische carbamat- und thiocarbamatbiaryle und verfahren zu deren herstellung
CN104208067A (zh) *	2004-07-07	2014-12-17	惠氏公司	周期性黄体酮方案及试剂盒
SI1778710T1 (sl) *	2004-08-13	2012-05-31	Wyeth Llc	Derivati tanaprogeta metaboliti in njihove uporabe
MX2007013469A (es) *	2005-04-28	2008-01-22	Wyeth Corp	Forma ii polimorfa de tanaproget.
DE602006007453D1 (de)	2005-04-28	2009-08-06	Wyeth Corp	Zusammensetzungen mit mikronisiertem tanaproget
AR056328A1 (es)	2005-04-28	2007-10-03	Wyeth Corp	TANAPROGET MICRONIZADO, COMPOSICIONES Y MÉTODOS PARA SU PREPARACIoN
EP1874743B1 (de) *	2005-04-28	2013-07-17	Wyeth LLC	Gereinigte form von tanaproget
US20060246128A1 (en) *	2005-04-28	2006-11-02	Wyeth	Micronized tanaproget and compositions containing same
CN103989687A (zh) *	2005-06-09	2014-08-20	惠氏公司	含有炔雌醇的tanaproget组合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0510235A1 (de) *	1991-04-26	1992-10-28	Dong-A Pharm. Co., Ltd.	Benzoxazin- oder Benzothiazinderivate und Verfahren zu deren Herstellung
JPH0510235A (ja) *	1991-07-05	1993-01-19	Nippondenso Co Ltd	内燃機関の点火時期制御装置
AU1694295A (en) *	1994-01-28	1995-08-15	Merck & Co., Inc.	Benzoxazinones as inhibitors of hiv reverse transcriptase
CZ176197A3 (cs) *	1994-12-22	1998-09-16	Ligand Pharmaceuticals Incorporated	Modulátory steroidových receptorů a způsoby jejich přípravy a použití
US5693647A (en) *	1994-12-22	1997-12-02	Ligand Pharmaceuticals Incorporated	Steroid receptor modulator compounds and methods
ATE248826T1 (de) *	1996-10-02	2003-09-15	Bristol Myers Squibb Pharma Co	4,4-disubstituierte 1,4-dihydro-2h-3,1-benzoxazin-2-one die anwendbar sind als hiv- reverstranskriptase-inhibitoren, zwischenprodukte und verfahren zu ihrer herstellung
MXPA01011287A (es) *	1999-05-04	2003-07-14	American Home Prod	Derivados de ciclotiocarbamato como moduladores de receptor de progesterona.
US20060246128A1 (en) *	2005-04-28	2006-11-02	Wyeth	Micronized tanaproget and compositions containing same
CN103989687A (zh) *	2005-06-09	2014-08-20	惠氏公司	含有炔雌醇的tanaproget组合物

2000
- 2000-05-01 MX MXPA01011287A patent/MXPA01011287A/es active IP Right Grant
- 2000-05-01 EA EA200101181A patent/EA004511B1/ru not_active IP Right Cessation
- 2000-05-01 SK SK1592-2001A patent/SK15922001A3/sk unknown
- 2000-05-01 CN CN008070997A patent/CN1131856C/zh not_active Expired - Fee Related
- 2000-05-01 AT AT00930266T patent/ATE386729T1/de not_active IP Right Cessation
- 2000-05-01 KR KR1020017014085A patent/KR100732692B1/ko not_active Expired - Fee Related
- 2000-05-01 GE GEAP20006120A patent/GEP20043181B/en unknown
- 2000-05-01 IL IL14629800A patent/IL146298A0/xx unknown
- 2000-05-01 AU AU48119/00A patent/AU766801B2/en not_active Ceased
- 2000-05-01 ES ES00930266T patent/ES2301482T3/es not_active Expired - Lifetime
- 2000-05-01 SG SG200400081A patent/SG120970A1/en unknown
- 2000-05-01 TR TR2001/03285T patent/TR200103285T2/xx unknown
- 2000-05-01 EP EP00930266A patent/EP1175411B1/de not_active Expired - Lifetime
- 2000-05-01 DK DK00930266T patent/DK1175411T3/da active
- 2000-05-01 CA CA002371712A patent/CA2371712C/en not_active Expired - Fee Related
- 2000-05-01 PL PL00351083A patent/PL351083A1/xx not_active Application Discontinuation
- 2000-05-01 JP JP2000615600A patent/JP4958338B2/ja not_active Expired - Fee Related
- 2000-05-01 DE DE60038108T patent/DE60038108T2/de not_active Expired - Lifetime
- 2000-05-01 NZ NZ515353A patent/NZ515353A/xx unknown
- 2000-05-01 HU HU0203332A patent/HUP0203332A3/hu unknown
- 2000-05-01 CZ CZ20013952A patent/CZ20013952A3/cs unknown
- 2000-05-01 BR BR0010214-8A patent/BR0010214A/pt active Search and Examination
2001
- 2001-11-02 BG BG106080A patent/BG65277B1/bg unknown
- 2001-11-02 NO NO20015381A patent/NO321370B1/no unknown
2011
- 2011-11-14 JP JP2011249051A patent/JP5523430B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2371712A1 (en)	2000-11-09
HUP0203332A3 (en)	2004-12-28
BG65277B1 (bg)	2007-11-30
DE60038108D1 (de)	2008-04-03
JP5523430B2 (ja)	2014-06-18
NZ515353A (en)	2004-03-26
CZ20013952A3 (cs)	2002-05-15
EP1175411B1 (de)	2008-02-20
JP2002543192A (ja)	2002-12-17
AU4811900A (en)	2000-11-17
KR20020000170A (ko)	2002-01-04
EP1175411A1 (de)	2002-01-30
NO20015381D0 (no)	2001-11-02
AU766801B2 (en)	2003-10-23
SG120970A1 (en)	2006-04-26
BR0010214A (pt)	2002-02-13
CN1349516A (zh)	2002-05-15
HUP0203332A2 (hu)	2003-01-28
SK15922001A3 (sk)	2002-09-10
EA200101181A1 (ru)	2002-04-25
KR100732692B1 (ko)	2007-06-27
NO321370B1 (no)	2006-05-02
EA004511B1 (ru)	2004-04-29
CN1131856C (zh)	2003-12-24
PL351083A1 (en)	2003-03-10
CA2371712C (en)	2009-12-22
BG106080A (en)	2002-05-31
MXPA01011287A (es)	2003-07-14
GEP20043181B (en)	2004-02-25
ES2301482T3 (es)	2008-07-01
JP2012087129A (ja)	2012-05-10
JP4958338B2 (ja)	2012-06-20
TR200103285T2 (tr)	2002-02-21
DE60038108T2 (de)	2009-02-12
IL146298A0 (en)	2002-07-25
DK1175411T3 (da)	2008-06-09
NO20015381L (no)	2002-01-03

Similar Documents

Publication	Publication Date	Title
UA72917C2 (en)	2005-05-16	Cyclic carbamates derivatives, pharmaceutical composition containing said derivatives of cyclic carbamates and active ingredients as modulators of the progesterone receptor
DE60038108D1 (de)	2008-04-03	Cyclothiocarbamatderivate als progesteron-rezeptormodulatoren
WO2000066564A8 (en)	2001-08-02	Benzimidazolones and analogues and their use as progesterone receptor ligands
BR0109855A (pt)	2003-06-03	Derivados de 8-isoquinolinxantina e 8-quinolixantina como inibidores de pde 5
HUP0300641A2 (hu)	2003-06-28	Triazaspiro[5.5]undekán-származékok és hatóanyagként ezeket tartalmazó gyógyszerkészítmények
HUP0204587A2 (en)	2003-05-28	6-position substituted indoline, production and use thereof as a medicament
AR035235A1 (es)	2004-05-05	Derivados heterocicliloxi-,-tioxi- y -aminobenzazol como ligandos de 5-hidroxitriptamina-6, un procedimiento para su preparacion, composicion farmaceutica, y el uso de dichos derivados para la manufactura de un medicamento
HUP0303652A2 (hu)	2004-03-01	Ciklikus származékok, mint kemokin receptor aktivitás modulátorai és ezeket tartalmazó gyógyszerkészítmények
AR030186A1 (es)	2003-08-13	Compuesto antibacteriano 3-aminoquinazolina-2,4-diona, composicion farmaceutica que lo comprende y su uso para fabricarla
AR007440A1 (es)	1999-10-27	Compuestos triciclos fenilamino sustituidos y composiciones farmaceuticas de los mismos.
BR0014901A (pt)	2002-06-11	Derivados de trifenil-alquenos e seu uso como moduladores de receptores seletivos de estrogênios
HUP9801688A2 (hu)	1999-03-29	Acetamidszármazékok, eljárás előállításukra és ilyen vegyületeket tartalmazó gyógyászati készítmények
AR035548A1 (es)	2004-06-16	Compuestos organicos
ATE204269T1 (de)	2001-09-15	Substituierte biphenyl- oder phenylpyridinderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
AR034203A1 (es)	2004-02-04	Derivados de 1-aril- o 1-alquilsulfonilbenzazol como ligandos de 5-hidroxitriptamina-6, un metodo para su preparacion, composicion farmaceutica y el uso de los mismos para la fabricacion de un medicamento
ATE194839T1 (de)	2000-08-15	Pyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
HUP9901096A2 (hu)	1999-07-28	Indolszármazékok, előállításuk és alkalmazásuk, a vegyületeket tartalmazó gyógyászati készítmények
EE9700227A (et)	1998-04-15	Arüülglütsiinamiidi derivaadid, meetod nende valmistamiseks ja neid ühendeid sisaldavad farmatseutilised preparaadid
PL309281A1 (en)	1995-10-02	Derivatives of 1,4-benzodiazepine and their application as cck modulators
HUP9700595A1 (hu)	2000-08-28	Fluor-alkil- és fluor-alkoxicsoporttal helyettesített heterociklikus bradikinin-antagonisták, eljárás ezek előállítására, valamint ezek alkalmazása
IL126278A0 (en)	1999-05-09	Novel 5-membered ring heterocycles their preparation their use and pharmaceutical preparations comprising them
NZ336189A (en)	2000-10-27	Diaza-spiro[3,5]nonane derivatives and use in treatment of diseases related to the orphanin receptor
CO5540322A2 (es)	2005-07-29	Nuevos derivados heterociclicos que comprenden un anillo de tetrahidroisoquinolina y uso farmaceutico de los mismos
YU75394A (sh)	1997-09-30	Anelirani dihidropiridini i njihova primena za pripremanje farmaceutskih preparata
ES2104370T3 (es)	1997-10-01	Derivados de (arilalquilaminobencil)aminopropionamidas sustituidas, su preparacion y utilizacion.

Legal Events

Date	Code	Title	Description
2008-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties