ATE390406T1 - Neue stabile kristalle substituierter phenylpropionsäurederivate und verfahren zu deren herstellung - Google Patents

Neue stabile kristalle substituierter phenylpropionsäurederivate und verfahren zu deren herstellung

Info

Publication number: ATE390406T1
Authority: AT; Austria
Prior art keywords: production; acid derivatives; phenylpropionic acid; new stable; stable crystals
Prior art date: 2001-12-11

Application number

AT02783815T

Other languages

English (en)

Inventor

Kazuo Orita

Tomomi Koike

Original Assignee

Kyorin Seiyaku Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-11

Filing date

2002-12-10

Publication date

2008-04-15

2002-12-10 Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk

2008-04-15 Application granted granted Critical

2008-04-15 Publication of ATE390406T1 publication Critical patent/ATE390406T1/de

Links

239000013078 crystal Substances 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
YPGCWEMNNLXISK-UHFFFAOYSA-N hydratropic acid Chemical class OC(=O)C(C)C1=CC=CC=C1 YPGCWEMNNLXISK-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
230000001747 exhibiting effect Effects 0.000 abstract 1
238000000634 powder X-ray diffraction Methods 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT02783815T 2001-12-11 2002-12-10 Neue stabile kristalle substituierter phenylpropionsäurederivate und verfahren zu deren herstellung ATE390406T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2001377077		2001-12-11

Publications (1)

Publication Number	Publication Date
ATE390406T1 true ATE390406T1 (de)	2008-04-15

Family

ID=19185129

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02783815T ATE390406T1 (de)	2001-12-11	2002-12-10	Neue stabile kristalle substituierter phenylpropionsäurederivate und verfahren zu deren herstellung

Country Status (14)

Country	Link
US (1)	US7279596B2 (de)
EP (1)	EP1462439B1 (de)
JP (1)	JP4424728B2 (de)
KR (1)	KR100876849B1 (de)
CN (1)	CN1312121C (de)
AT (1)	ATE390406T1 (de)
AU (1)	AU2002349538B2 (de)
CA (1)	CA2469882C (de)
CY (1)	CY1107417T1 (de)
DE (1)	DE60225841T2 (de)
DK (1)	DK1462439T3 (de)
ES (1)	ES2302857T3 (de)
PT (1)	PT1462439E (de)
WO (1)	WO2003050077A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2005272389B2 (en) *	2004-08-11	2011-08-04	Kyorin Pharmaceutical Co., Ltd.	Novel cyclic aminobenzoic acid derivative
JP2007001912A (ja) *	2005-06-22	2007-01-11	Univ Of Tokyo	置換フェニルプロピオン酸誘導体
CN103951583B (zh) *	2006-12-06	2016-01-06	科内图斯医药公司	一种抑制剂的结晶形式

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4618845B2 (ja) *	1999-06-09	2011-01-26	杏林製薬株式会社	ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体
US6706763B1 (en) *	1999-09-17	2004-03-16	Kyorin Pharmaceutical Co., Ltd.	O-anisamide derivatives
TWI262185B (en)	1999-10-01	2006-09-21	Eisai Co Ltd	Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives

2002
- 2002-12-10 DK DK02783815T patent/DK1462439T3/da active
- 2002-12-10 AT AT02783815T patent/ATE390406T1/de active
- 2002-12-10 ES ES02783815T patent/ES2302857T3/es not_active Expired - Lifetime
- 2002-12-10 KR KR1020047008935A patent/KR100876849B1/ko not_active Expired - Fee Related
- 2002-12-10 CA CA002469882A patent/CA2469882C/en not_active Expired - Fee Related
- 2002-12-10 EP EP02783815A patent/EP1462439B1/de not_active Expired - Lifetime
- 2002-12-10 CN CNB028245946A patent/CN1312121C/zh not_active Expired - Fee Related
- 2002-12-10 DE DE60225841T patent/DE60225841T2/de not_active Expired - Lifetime
- 2002-12-10 PT PT02783815T patent/PT1462439E/pt unknown
- 2002-12-10 US US10/497,174 patent/US7279596B2/en not_active Expired - Fee Related
- 2002-12-10 WO PCT/JP2002/012892 patent/WO2003050077A1/ja not_active Ceased
- 2002-12-10 JP JP2003551104A patent/JP4424728B2/ja not_active Expired - Fee Related
- 2002-12-10 AU AU2002349538A patent/AU2002349538B2/en not_active Ceased
2008
- 2008-04-21 CY CY20081100446T patent/CY1107417T1/el unknown

Also Published As

Publication number	Publication date
JP4424728B2 (ja)	2010-03-03
EP1462439B1 (de)	2008-03-26
PT1462439E (pt)	2008-04-10
US7279596B2 (en)	2007-10-09
US20050228050A1 (en)	2005-10-13
DE60225841D1 (de)	2008-05-08
CY1107417T1 (el)	2012-12-19
CN1602295A (zh)	2005-03-30
CA2469882C (en)	2009-09-29
WO2003050077A1 (fr)	2003-06-19
AU2002349538A1 (en)	2003-06-23
CA2469882A1 (en)	2003-06-19
KR100876849B1 (ko)	2008-12-31
EP1462439A4 (de)	2006-02-01
ES2302857T3 (es)	2008-08-01
KR20040075000A (ko)	2004-08-26
DE60225841T2 (de)	2009-05-14
AU2002349538B2 (en)	2006-04-27
CN1312121C (zh)	2007-04-25
EP1462439A1 (de)	2004-09-29
DK1462439T3 (da)	2008-04-21
JPWO2003050077A1 (ja)	2005-04-21

Similar Documents

Publication	Publication Date	Title
ATE440817T1 (de)	2009-09-15	Bicalutamidkristalle und verfahren zu deren herstellung
CA2334775A1 (en)	1999-12-16	Benzo(b)thiepine-1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
ATE260896T1 (de)	2004-03-15	Donepezil polykristalle und verfharen zu ihrer herstellung
DK282188A (da)	1988-11-26	Cykliske aminderivater, laegemidler indeholdende forbindelserne og fremgangsmaader til deres fremstilling
TR200102771T2 (tr)	2002-04-22	Kristalleştirme ile elde edilen aglomeralar
ES2105362T3 (es)	1997-10-16	Nuevos derivados de acidos quinolon- y naftiridoncarboxilicos.
ATE48835T1 (de)	1990-01-15	Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope.
ATE47856T1 (de)	1989-11-15	11-substituierte 5h,11h-pyrrolo(2,1c>(1,4>benzoxazepine, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE60225841D1 (de)	2008-05-08	Neue stabile kristalle substituierter phenylpropionsäurederivate und verfahren zu deren herstellung
ATE261966T1 (de)	2004-04-15	Wasserfreie mirtazapin-kristalle und ein verfahren zu ihrer herstellung
DE69909165D1 (de)	2003-08-07	Verfahren zur Herstellung von N-Glycyltyrosin
ATE172976T1 (de)	1998-11-15	3-aminochroman-spiroderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
BR9707004A (pt)	1999-07-20	Composto processo para preparar o mesmo composição farmacêutica utilização do composto e processos para tratamento de doenças do sistema endocinológico e para a manufatura de um medicamento
ATE140213T1 (de)	1996-07-15	N-monosubstituierte cyclopentenylamine, ein verfahren zu ihrer herstellung, und ihre verwendung als medikament
DK0401623T3 (da)	2000-07-17	Fremgangsmåde til fremstilling af 7-(3-amino- og 3-aminomethyl-1-pyrrolidinyl)-3-quinoloncarboxylsyrer og -napthyridoncarbo
DK0469547T3 (da)	1996-06-10	4-Amino-delta4,6-steroider og deres anvendelse som inhibitorer af 5alfa-reduktase
DE3280245D1 (de)	1990-10-25	Imidazolverbindungen, verfahren zu deren herstellung und deren pharmazeutische zusammensetzungen.
ATE419230T1 (de)	2009-01-15	Verfahren zur herstellung von 2,6-dihalo-para- trifluoromethylanilin
ATE382624T1 (de)	2008-01-15	Kristalle von taxanderivaten und verfahren zu deren herstellung
BR0210512A (pt)	2004-06-22	Processo de decomposição papa o ácido (r)-(-)-2-hidroxi-2-(2-clorofenil) acético
CA2363875A1 (en)	2000-08-31	Method crystallising n-(4-trifluoromethylphenyl)-5-methyl-isoxazole-4-carboxamide
CN100491333C (zh)	2009-05-27	高纯度烯胺类的制备方法
DE60133995D1 (de)	2008-06-26	Neues kristallines stilben-derivat und verfahren zu dessen herstellung
ATE193703T1 (de)	2000-06-15	N-benzylpiperazinverbindungen, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen
DK527483D0 (da)	1983-11-17	Fremgangsmade til fremstilling af benzazepinderivater

Legal Events

Date

Code

Title

Description

2008-09-15

UEP

Publication of translation of european patent specification

Ref document number: 1462439

Country of ref document: EP