ATE391127T1 - Indolylmaleimidderivate - Google Patents

Indolylmaleimidderivate

Info

Publication number: ATE391127T1
Authority: AT; Austria
Prior art keywords: indolylmaleimide derivatives; indolylmaleimide; derivatives; pkc; isoforms
Prior art date: 2004-01-19

Application number

AT05701051T

Other languages

English (en)

Inventor

Eis Maurice Van

Matt Peter Von

Juergen Wagner

Jean-Pierre Evenou

Original Assignee

Novartis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-19

Filing date

2005-01-19

Publication date

2008-04-15

2004-01-19 Priority claimed from GB0401089A external-priority patent/GB0401089D0/en

2004-01-19 Priority claimed from GB0401090A external-priority patent/GB0401090D0/en

2005-01-19 Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh

2008-04-15 Application granted granted Critical

2008-04-15 Publication of ATE391127T1 publication Critical patent/ATE391127T1/de

Links

WIQRSJOCVVPMPS-UHFFFAOYSA-N 3-(1h-indol-2-yl)pyrrole-2,5-dione Chemical class O=C1NC(=O)C(C=2NC3=CC=CC=C3C=2)=C1 WIQRSJOCVVPMPS-UHFFFAOYSA-N 0.000 title 1
102000001708 Protein Isoforms Human genes 0.000 abstract 1
108010029485 Protein Isoforms Proteins 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
238000002054 transplantation Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Virology (AREA)
Reproductive Health (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Orthopedic Medicine & Surgery (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Emergency Medicine (AREA)
Transplantation (AREA)
Psychiatry (AREA)

AT05701051T 2004-01-19 2005-01-19 Indolylmaleimidderivate ATE391127T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0401089A GB0401089D0 (en)	2004-01-19	2004-01-19	Organic compounds
GB0401090A GB0401090D0 (en)	2004-01-19	2004-01-19	Organic compounds

Publications (1)

Publication Number	Publication Date
ATE391127T1 true ATE391127T1 (de)	2008-04-15

Family

ID=34796827

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05701051T ATE391127T1 (de)	2004-01-19	2005-01-19	Indolylmaleimidderivate

Country Status (15)

Country	Link
US (2)	US7648989B2 (de)
EP (3)	EP1745037B1 (de)
JP (2)	JP2007518730A (de)
CN (1)	CN101933926A (de)
AT (1)	ATE391127T1 (de)
AU (3)	AU2005205183B2 (de)
BR (2)	BRPI0506958A (de)
CA (2)	CA2552740A1 (de)
DE (1)	DE602005005787T2 (de)
ES (2)	ES2303218T3 (de)
MX (1)	MXPA06008158A (de)
PL (1)	PL1709030T3 (de)
PT (1)	PT1709030E (de)
RU (2)	RU2372348C2 (de)
WO (2)	WO2005068455A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2007006533A2 (en)	2005-07-11	2007-01-18	Novartis Ag	Indolylmaleimide derivatives
US20070148628A1 (en) *	2005-12-09	2007-06-28	Philadelphia College Of Osteopathic Medicine	Organ preservation and/or perfusion
DK2056851T3 (da) *	2005-12-09	2013-10-14	Philadelphia College Of Osteopathic Medicine	Organkonservering og/eller -perfusion
CN101583358A (zh) *	2006-12-07	2009-11-18	诺瓦提斯公司	Pkc抑制剂在移植中的用途
CN102838610B (zh) *	2012-08-28	2014-09-10	吕叶叶	双吲哚二氧杂双环辛二酮
WO2016179517A1 (en)	2015-05-07	2016-11-10	Agenus Inc.	Anti-ox40 antibodies and methods of use thereof
PL3328827T3 (pl)	2015-07-31	2023-11-27	The Johns Hopkins University	Proleki analogów glutaminy
US10842763B2 (en)	2015-07-31	2020-11-24	The Johns Hopkins University	Methods for cancer and immunotherapy using prodrugs of glutamine analogs
CA2994256A1 (en)	2015-07-31	2017-02-09	The Johns Hopkins University	Methods and compositions for treating metabolic reprogramming disorders
WO2017096179A1 (en)	2015-12-02	2017-06-08	Agenus Inc.	Antibodies and methods of use thereof
MA46770A (fr)	2016-11-09	2019-09-18	Agenus Inc	Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
EP3576727A4 (de)	2017-02-01	2020-09-09	The Johns Hopkins University	Prodrugs von glutaminanaloga
CN110551103B (zh) *	2018-05-30	2022-08-23	北京大学深圳研究生院	一种jak3选择性抑制剂

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US36736A (en) *		1862-10-21		Improvement in curry-combs
IL89167A (en) *	1988-02-10	1994-02-27	Hoffmann La Roche	Substituted pyrroles, their manufacture and pharmaceutical compositions containing them
USRE36736E (en)	1989-02-06	2000-06-13	Hoffman-La Roche Inc.	Substituted pyrroles
MC2096A1 (fr) *	1989-02-23	1991-02-15	Hoffmann La Roche	Pyrroles substitues
DE3942296A1 (de) *	1989-12-21	1991-06-27	Goedecke Ag	Indolocarbazol-derivate, verfahren zu deren herstellung und deren verwendung
SG63570A1 (en) *	1993-12-07	1999-03-30	Lilly Co Eli	Protein kinase c inhibitors
ES2332770T3 (es) *	2000-11-07	2010-02-12	Novartis Ag	Derivados de indolilmaleimida como inhibidores de la proteina quinasa c.
US6645970B2 (en) *	2000-11-07	2003-11-11	Novartis Ag	Indolylmaleimide derivatives
BE1014306A6 (fr)	2001-07-19	2003-08-05	Project 21C	Dispositif de stationnement d'un cycle avec antivol.
TW200918046A (en) *	2002-04-03	2009-05-01	Novartis Ag	Indolylmaleimide derivatives
ES2312785T3 (es) *	2002-06-05	2009-03-01	Janssen Pharmaceutica Nv	Pirrolinas sustituidas utiles como inhibidores de quinasa.

2005
- 2005-01-19 AT AT05701051T patent/ATE391127T1/de active
- 2005-01-19 PL PL05701051T patent/PL1709030T3/pl unknown
- 2005-01-19 BR BRPI0506958-0A patent/BRPI0506958A/pt not_active IP Right Cessation
- 2005-01-19 CA CA002552740A patent/CA2552740A1/en not_active Abandoned
- 2005-01-19 EP EP05701052A patent/EP1745037B1/de not_active Expired - Lifetime
- 2005-01-19 ES ES05701051T patent/ES2303218T3/es not_active Expired - Lifetime
- 2005-01-19 ES ES05701052T patent/ES2402298T3/es not_active Expired - Lifetime
- 2005-01-19 RU RU2006129891/04A patent/RU2372348C2/ru not_active IP Right Cessation
- 2005-01-19 EP EP05701051A patent/EP1709030B1/de not_active Expired - Lifetime
- 2005-01-19 BR BRPI0506939-4A patent/BRPI0506939A/pt not_active IP Right Cessation
- 2005-01-19 AU AU2005205183A patent/AU2005205183B2/en not_active Ceased
- 2005-01-19 WO PCT/EP2005/000502 patent/WO2005068455A1/en not_active Ceased
- 2005-01-19 JP JP2006548286A patent/JP2007518730A/ja active Pending
- 2005-01-19 WO PCT/EP2005/000501 patent/WO2005068454A1/en not_active Ceased
- 2005-01-19 RU RU2006129890/04A patent/RU2373201C2/ru not_active IP Right Cessation
- 2005-01-19 CN CN2010101594600A patent/CN101933926A/zh active Pending
- 2005-01-19 JP JP2006548287A patent/JP4914223B2/ja not_active Expired - Fee Related
- 2005-01-19 PT PT05701051T patent/PT1709030E/pt unknown
- 2005-01-19 MX MXPA06008158A patent/MXPA06008158A/es not_active Application Discontinuation
- 2005-01-19 US US10/586,421 patent/US7648989B2/en not_active Expired - Fee Related
- 2005-01-19 DE DE602005005787T patent/DE602005005787T2/de not_active Expired - Lifetime
- 2005-01-19 EP EP10012694A patent/EP2270001A1/de not_active Withdrawn
- 2005-01-19 CA CA002552738A patent/CA2552738A1/en not_active Abandoned
- 2005-01-19 AU AU2005205182A patent/AU2005205182B2/en not_active Ceased
- 2005-01-19 US US10/586,420 patent/US7691861B2/en not_active Expired - Fee Related
2009
- 2009-10-16 AU AU2009227818A patent/AU2009227818A1/en not_active Abandoned

Also Published As

Publication number	Publication date
RU2006129890A (ru)	2008-02-27
BRPI0506958A (pt)	2007-07-24
EP1709030A1 (de)	2006-10-11
BRPI0506939A (pt)	2007-06-12
JP2007518731A (ja)	2007-07-12
EP1745037B1 (de)	2013-01-02
JP4914223B2 (ja)	2012-04-11
CN101933926A (zh)	2011-01-05
RU2372348C2 (ru)	2009-11-10
RU2373201C2 (ru)	2009-11-20
WO2005068455A1 (en)	2005-07-28
PL1709030T3 (pl)	2008-09-30
CA2552740A1 (en)	2005-07-28
MXPA06008158A (es)	2007-01-30
AU2005205183B2 (en)	2009-08-06
EP2270001A1 (de)	2011-01-05
AU2005205183A1 (en)	2005-07-28
EP1745037A1 (de)	2007-01-24
PT1709030E (pt)	2008-07-01
ES2402298T3 (es)	2013-04-30
US7648989B2 (en)	2010-01-19
EP1709030B1 (de)	2008-04-02
ES2303218T3 (es)	2008-08-01
AU2005205182A1 (en)	2005-07-28
CA2552738A1 (en)	2005-07-28
AU2009227818A1 (en)	2009-11-05
US7691861B2 (en)	2010-04-06
US20080234494A1 (en)	2008-09-25
JP2007518730A (ja)	2007-07-12
DE602005005787T2 (de)	2009-04-30
WO2005068454A1 (en)	2005-07-28
DE602005005787D1 (de)	2008-05-15
RU2006129891A (ru)	2008-02-27
AU2005205182B2 (en)	2009-07-16
US20080242675A1 (en)	2008-10-02

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2008-11-15

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