ATE398181T1 - Hefezellen welche zumindest zwei kopien von einem erwünschten gens enthalt und integrierte in dem chromosomal genom auf mehr als einem nicht- ribosomaler rns kodierende bereich, ins besonders mit kluyveromyces - Google Patents
Hefezellen welche zumindest zwei kopien von einem erwünschten gens enthalt und integrierte in dem chromosomal genom auf mehr als einem nicht- ribosomaler rns kodierende bereich, ins besonders mit kluyveromycesInfo
- Publication number
- ATE398181T1 ATE398181T1 AT98928202T AT98928202T ATE398181T1 AT E398181 T1 ATE398181 T1 AT E398181T1 AT 98928202 T AT98928202 T AT 98928202T AT 98928202 T AT98928202 T AT 98928202T AT E398181 T1 ATE398181 T1 AT E398181T1
- Authority
- AT
- Austria
- Prior art keywords
- desired gene
- copies
- ribosomal rna
- yeast cells
- kluyveromyces
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 210000005253 yeast cell Anatomy 0.000 title abstract 3
- 230000002759 chromosomal effect Effects 0.000 title abstract 2
- 241000235649 Kluyveromyces Species 0.000 title 1
- 108020004418 ribosomal RNA Proteins 0.000 abstract 2
- 230000010354 integration Effects 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97201053 | 1997-04-11 | ||
| EP97201637 | 1997-06-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE398181T1 true ATE398181T1 (de) | 2008-07-15 |
Family
ID=26146351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98928202T ATE398181T1 (de) | 1997-04-11 | 1998-04-14 | Hefezellen welche zumindest zwei kopien von einem erwünschten gens enthalt und integrierte in dem chromosomal genom auf mehr als einem nicht- ribosomaler rns kodierende bereich, ins besonders mit kluyveromyces |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0973918B1 (de) |
| JP (1) | JP4531868B2 (de) |
| AT (1) | ATE398181T1 (de) |
| AU (1) | AU8013798A (de) |
| DE (1) | DE69839602D1 (de) |
| DK (1) | DK0973918T3 (de) |
| ES (1) | ES2308805T3 (de) |
| WO (1) | WO1998046774A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3293264A1 (de) | 2009-07-22 | 2018-03-14 | DSM IP Assets B.V. | Verbesserte wirtszelle für die herstellung von relevanten produkten |
| CA3056920A1 (en) | 2017-03-29 | 2018-10-04 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Recombinant host cell with altered membrane lipid composition |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59501572A (ja) * | 1982-05-19 | 1984-09-06 | ユニリーバー ナームローゼ ベンノートシヤープ | クルイベロミセス属酵母およびその製造法 |
| WO1991000920A2 (en) * | 1989-07-07 | 1991-01-24 | Unilever N.V. | Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector |
| IT1251435B (it) * | 1991-09-04 | 1995-05-09 | Sclavo Spa | Vettore genetico per la integrazione multipla stabile di sequenze di dna nel genoma dei lieviti kluyveromyces lactis e saccharomyces cerevisiae e plasmidi che lo contengono. |
| DE69432543T2 (de) * | 1993-07-23 | 2003-12-24 | Dsm N.V., Te Heerlen | Selektionmarker-genfreie rekombinante Stämme: Verfahren zur ihrer Herstellung und die Verwendung dieser Stämme |
-
1998
- 1998-04-14 AT AT98928202T patent/ATE398181T1/de active
- 1998-04-14 DE DE69839602T patent/DE69839602D1/de not_active Expired - Lifetime
- 1998-04-14 ES ES98928202T patent/ES2308805T3/es not_active Expired - Lifetime
- 1998-04-14 AU AU80137/98A patent/AU8013798A/en not_active Abandoned
- 1998-04-14 WO PCT/EP1998/002261 patent/WO1998046774A1/en not_active Ceased
- 1998-04-14 EP EP98928202A patent/EP0973918B1/de not_active Expired - Lifetime
- 1998-04-14 DK DK98928202T patent/DK0973918T3/da active
- 1998-04-14 JP JP54351098A patent/JP4531868B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998046774A1 (en) | 1998-10-22 |
| EP0973918B1 (de) | 2008-06-11 |
| DE69839602D1 (de) | 2008-07-24 |
| ES2308805T3 (es) | 2008-12-01 |
| JP2002514077A (ja) | 2002-05-14 |
| JP4531868B2 (ja) | 2010-08-25 |
| EP0973918A1 (de) | 2000-01-26 |
| DK0973918T3 (da) | 2008-09-22 |
| AU8013798A (en) | 1998-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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