|
US20030215422A1
(en)
|
1996-09-11 |
2003-11-20 |
John A. Chiorini |
Aav4 vector and uses thereof
|
|
US6759237B1
(en)
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
|
CA2348382C
(en)
|
1998-11-10 |
2013-09-17 |
The University Of North Carolina At Chapel Hill |
Chimeric parvovirus vectors and methods of making and administering the same
|
|
WO2001025253A2
(en)
|
1999-10-01 |
2001-04-12 |
The University Of North Carolina At Chapel Hill |
Temperature-sensitive regulation of viral vector production
|
|
US6855314B1
(en)
*
|
2000-03-22 |
2005-02-15 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector for transducing brain cells and lung cells
|
|
AU2001250922A1
(en)
*
|
2000-03-22 |
2001-10-03 |
Board Of Trustees Of The University Of Arkansas |
Secreting products from skin by adeno-associated virus (aav) gene transfer
|
|
EP1285078A2
(de)
|
2000-04-28 |
2003-02-26 |
The Trustees of The University of Pennsylvania |
Rekombinante aav vektoren mit aav5 kapsiden und aav5 vektoren pseudotypisiert in heterologen kapsiden
|
|
WO2002082904A2
(en)
|
2001-04-13 |
2002-10-24 |
The Trustees Of The University Of Pennsylvania |
Method of treating or retarding the development of blindness
|
|
DE10120265A1
(de)
*
|
2001-04-25 |
2002-11-14 |
Deutsches Krebsforsch |
AAV-Helferplasmide zur Helfervirus-freien Verpackung und Pseudotypisierung von AAV-Vektoren
|
|
US7271150B2
(en)
|
2001-05-14 |
2007-09-18 |
United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Modified growth hormone
|
|
US8241622B2
(en)
|
2001-07-13 |
2012-08-14 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors with intravector heterologous terminal palindromic sequences
|
|
MX359371B
(es)
|
2001-11-13 |
2018-09-25 |
Univ Pennsylvania |
Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo.
|
|
EP1453547B1
(de)
|
2001-12-17 |
2016-09-21 |
The Trustees Of The University Of Pennsylvania |
Adeno-assoziierte virus (aav) serotyp 8 sequenzen, diese enthaltende vektoren und ihre verwendung
|
|
DK1463805T3
(en)
|
2001-12-17 |
2015-01-19 |
Univ Pennsylvania |
Sequences of adeno-associated virus (AAV) serotype 9, vectors containing these as well as their uses
|
|
US7419817B2
(en)
|
2002-05-17 |
2008-09-02 |
The United States Of America As Represented By The Secretary Department Of Health And Human Services, Nih. |
Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
|
|
US8927269B2
(en)
|
2003-05-19 |
2015-01-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Avian adenoassociated virus and uses thereof
|
|
WO2005021768A1
(en)
*
|
2003-09-01 |
2005-03-10 |
Academisch Medisch Centrum |
Aav vectors for in vivo gene therapy of rheumatoid arthritis
|
|
NZ545656A
(en)
|
2003-09-01 |
2009-02-28 |
Amc Amsterdam |
AAV vectors for in vivo gene therapy of rheumatoid arthritis
|
|
EP2345731B1
(de)
|
2003-09-30 |
2015-10-21 |
The Trustees of the University of Pennsylvania |
Adenoassoziierte Virus-Claden, Sequenzen, diese enthaltende Vektoren und ihre Verwendungen
|
|
WO2005056807A2
(en)
*
|
2003-12-04 |
2005-06-23 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, National Institutes Of Health |
Bovine adeno-associated viral (baav) vector and uses thereof
|
|
ES2616337T3
(es)
|
2003-12-12 |
2017-06-12 |
Government Of The United States Of America, As Repr. By The Secr. Of The Dept. Of Health And Human Services And His Successors |
Un epítopo de linfocito T citotóxico humano y su epítopo agonista del número no variable de secuencias de repetición en tándem de MUC-1
|
|
WO2006029196A1
(en)
*
|
2004-09-08 |
2006-03-16 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, National Institutes Of H Ealth |
Transcytosis of adeno-associated viruses
|
|
NZ555830A
(en)
|
2004-12-15 |
2009-01-31 |
Univ North Carolina |
Chimeric vectors
|
|
US8999678B2
(en)
|
2005-04-07 |
2015-04-07 |
The Trustees Of The University Of Pennsylvania |
Method of increasing the function of an AAV vector
|
|
WO2006119432A2
(en)
|
2005-04-29 |
2006-11-09 |
The Government Of The U.S.A., As Rep. By The Sec., Dept. Of Health & Human Services |
Isolation, cloning and characterization of new adeno-associated virus (aav) serotypes
|
|
WO2007109583A2
(en)
|
2006-03-17 |
2007-09-27 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Compositions and methods for prevention or treatment of neoplastic disease in a mammalian subject
|
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
|
WO2010093784A2
(en)
|
2009-02-11 |
2010-08-19 |
The University Of North Carolina At Chapel Hill |
Modified virus vectors and methods of making and using the same
|
|
JP2012521750A
(ja)
|
2009-03-27 |
2012-09-20 |
プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ |
肝硬変及び肝線維症の治療のための方法及び組成物
|
|
WO2010138263A2
(en)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Novel aav 's and uses thereof
|
|
EP2497830A1
(de)
|
2009-11-05 |
2012-09-12 |
Proyecto de Biomedicina Cima, S.L. |
Regulierte expressionssysteme
|
|
WO2011088081A1
(en)
|
2010-01-12 |
2011-07-21 |
The University Of North Carolina At Chapel Hill |
Restrictive inverted terminal repeats for viral vectors
|
|
JP2013533847A
(ja)
|
2010-04-23 |
2013-08-29 |
ユニバーシティ オブ マサチューセッツ |
コレステロール関連障害のaavベースの治療
|
|
US9546369B2
(en)
|
2010-04-23 |
2017-01-17 |
University Of Massachusetts |
Multicistronic expression constructs
|
|
ES2605305T3
(es)
|
2010-04-23 |
2017-03-13 |
University Of Massachusetts |
Vectores de AAV que se dirigen al SNC y métodos de uso de los mismos
|
|
ES2711256T3
(es)
*
|
2010-04-23 |
2019-04-30 |
Univ Florida |
Composiciones de rAAV-guanilato ciclasa y métodos para tratar la amaurosis congénita de Leber 1 (LCA1)
|
|
WO2012007458A1
(en)
|
2010-07-12 |
2012-01-19 |
Universidad Autónoma De Barcelona |
Gene therapy composition for use in diabetes treatment
|
|
WO2012145624A2
(en)
|
2011-04-21 |
2012-10-26 |
University Of Massachusetts |
Raav-based compositions and methods for treating alpha-1 anti-trypsin deficiencies
|
|
RU2611202C2
(ru)
|
2011-04-22 |
2017-02-21 |
Те Риджентс Оф Те Юниверсити Оф Калифорния |
Вирионы аденоассоциированного вируса с вариантным капсидом и способы их использования
|
|
BR112014020127A2
(pt)
*
|
2012-02-14 |
2020-06-30 |
The Regents Of The University Of Calefornia |
métodos para tratamento, melhoramento ou proteção (prevenção) de um indivíduo ou um paciente, e de uma disfunção, uma doença, uma infecção ou uma condição, e, método para suprimir o ganho de peso, ou suprimir o apepite, ou estimular ou iniciar a perda de peso
|
|
EP2692868A1
(de)
|
2012-08-02 |
2014-02-05 |
Universitat Autònoma De Barcelona |
Adenoassoziierte virale (AAV) Vektoren für die Transduktion von Fettgewebe
|
|
DK2900686T3
(da)
|
2012-09-28 |
2020-08-17 |
Univ North Carolina Chapel Hill |
Aav-vektorer targeteret til oligodendrocytter
|
|
US9597357B2
(en)
|
2012-10-10 |
2017-03-21 |
Sangamo Biosciences, Inc. |
T cell modifying compounds and uses thereof
|
|
WO2014143932A1
(en)
|
2013-03-15 |
2014-09-18 |
The University Of North Carolina At Chapel Hill |
Synthetic adeno-associated virus inverted terminal repeats
|
|
EP3008191A2
(de)
|
2013-06-13 |
2016-04-20 |
Shire Human Genetic Therapies, Inc. |
Virenproduktion auf messenger-rna-basis
|
|
KR102445330B1
(ko)
*
|
2013-07-12 |
2022-09-19 |
더 칠드런스 호스피탈 오브 필라델피아 |
Aav 벡터 및 항―aav (아데노-관련 바이러스) 중화 항체에 대한 검정
|
|
WO2015044292A1
(en)
|
2013-09-26 |
2015-04-02 |
Universitat Autonoma De Barcelona |
Gene therapy compositions for use in the prevention and/or treatment of non-alcoholic fatty liver disease
|
|
PL3102722T3
(pl)
|
2014-02-04 |
2021-03-08 |
Jumpcode Genomics, Inc. |
Frakcjonowanie genomu
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
US10072251B2
(en)
|
2014-02-19 |
2018-09-11 |
University Of Massachusetts |
Recombinant AAVS having useful transcytosis properties
|
|
EP3778627A1
(de)
|
2014-03-09 |
2021-02-17 |
The Trustees of The University of Pennsylvania |
Zusammensetzungen für die behandlung des mangels von ornithin-transcarbamylase (otc)
|
|
DK3117005T3
(da)
|
2014-03-10 |
2024-08-12 |
Uniqure Ip Bv |
Yderligere forbedrede AVV-vektorer, der er produceret i insektceller
|
|
EP3119797B1
(de)
|
2014-03-18 |
2020-12-23 |
University of Massachusetts |
Zusammensetzungen und verfahren zur behandlung von amyotropher lateralsklerose
|
|
WO2015164786A1
(en)
|
2014-04-25 |
2015-10-29 |
University Of Massachusetts |
Recombinant aav vectors useful for reducing immunity against transgene products
|
|
WO2015187825A2
(en)
|
2014-06-03 |
2015-12-10 |
University Of Massachusetts |
Compositions and methods for modulating dysferlin expression
|
|
US10577627B2
(en)
|
2014-06-09 |
2020-03-03 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
US9458464B2
(en)
|
2014-06-23 |
2016-10-04 |
The Johns Hopkins University |
Treatment of neuropathic pain
|
|
CA2960912A1
(en)
|
2014-09-16 |
2016-03-24 |
Universitat Autonoma De Barcelona |
Adeno-associated viral vectors for the gene therapy of metabolic diseases
|
|
US10711270B2
(en)
|
2014-10-03 |
2020-07-14 |
University Of Massachusetts |
High efficiency library-identified AAV vectors
|
|
US10370432B2
(en)
|
2014-10-03 |
2019-08-06 |
University Of Massachusetts |
Heterologous targeting peptide grafted AAVS
|
|
RU2020140209A
(ru)
*
|
2014-10-21 |
2021-01-25 |
Юниверсити Оф Массачусетс |
Варианты рекомбинантных aav и их применения
|
|
MX2017005834A
(es)
|
2014-11-05 |
2017-11-17 |
Voyager Therapeutics Inc |
Polinucleotidos aad para el tratamiento de la enfermedad de parkinson.
|
|
SG10202001102XA
(en)
|
2014-11-14 |
2020-03-30 |
Voyager Therapeutics Inc |
Modulatory polynucleotides
|
|
CN107109407A
(zh)
|
2014-11-14 |
2017-08-29 |
沃雅戈治疗公司 |
治疗肌萎缩性侧索硬化(als)的组合物和方法
|
|
CN114480440A
(zh)
|
2014-11-21 |
2022-05-13 |
北卡罗来纳-查佩尔山大学 |
靶向中枢神经系统的aav载体
|
|
WO2016094783A1
(en)
|
2014-12-12 |
2016-06-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the production of scaav
|
|
EP3978614A3
(de)
|
2015-01-07 |
2022-07-27 |
Universitat Autònoma de Barcelona |
Einzelvektor-genkonstrukt mit insulin und glucokinasegenen
|
|
EP3245220B1
(de)
|
2015-01-14 |
2023-09-20 |
The University of North Carolina at Chapel Hill |
Verfahren und zusammensetzungen für gezielten gentransfer
|
|
CN107531774B
(zh)
|
2015-02-06 |
2021-12-14 |
北卡罗来纳大学查珀尔希尔分校 |
优化的人类凝血因子viii基因表达盒及其用途
|
|
WO2016131009A1
(en)
|
2015-02-13 |
2016-08-18 |
University Of Massachusetts |
Compositions and methods for transient delivery of nucleases
|
|
US10968536B2
(en)
|
2015-02-25 |
2021-04-06 |
Jumpcode Genomics, Inc. |
Methods and compositions for sequencing
|
|
US10081659B2
(en)
|
2015-04-06 |
2018-09-25 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Adeno-associated vectors for enhanced transduction and reduced immunogenicity
|
|
CA3021949C
(en)
|
2015-04-24 |
2023-10-17 |
University Of Massachusetts |
Modified aav constructs and uses thereof
|
|
US20190000943A1
(en)
*
|
2015-08-13 |
2019-01-03 |
Aavet Therapeutics, Llc |
Aav6 vectors for immunotherapy
|
|
ES2865487T3
(es)
|
2015-09-28 |
2021-10-15 |
Univ North Carolina Chapel Hill |
Métodos y composiciones para vectores virales que evaden los anticuerpos
|
|
EP3355924A1
(de)
|
2015-09-29 |
2018-08-08 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Verfahren zur behandlung und prävention von amyotropher lateralsklerose
|
|
US11253576B2
(en)
|
2015-10-22 |
2022-02-22 |
University Of Massachusetts |
Methods and compositions for treating metabolic imbalance in neurodegenerative disease
|
|
CA3002980A1
(en)
|
2015-10-22 |
2017-04-27 |
University Of Massachusetts |
Prostate-targeting adeno-associated virus serotype vectors
|
|
BR112018007453A2
(pt)
|
2015-11-05 |
2018-10-23 |
Bamboo Therapeutics Inc |
genes modificados de ataxia de friedreich e vetores para a terapia gênica
|
|
AU2016362477A1
(en)
|
2015-12-02 |
2018-06-14 |
Voyager Therapeutics, Inc. |
Assays for the detection of AAV neutralizing antibodies
|
|
EP3390429B1
(de)
|
2015-12-14 |
2025-06-18 |
The University of North Carolina at Chapel Hill |
Modifizierte kapsidproteine zur verbesserten abgabe von parvovirus-vektoren
|
|
WO2017129822A1
(en)
*
|
2016-01-29 |
2017-08-03 |
Sirion Biotech Gmbh |
Aav-based conditional expression system
|
|
US11826433B2
(en)
|
2016-02-02 |
2023-11-28 |
University Of Massachusetts |
Method to enhance the efficiency of systemic AAV gene delivery to the central nervous system
|
|
FI3411484T3
(fi)
|
2016-02-05 |
2023-11-15 |
Univ Emory |
Yksisäikeisen tai itsekomplementaarisen adenoassosioidun viruksen 9 injektio serebrospinaaliseen fluidiin
|
|
WO2017139381A1
(en)
|
2016-02-08 |
2017-08-17 |
University Of Iowa Research Foundation |
Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
|
|
US11339427B2
(en)
|
2016-02-12 |
2022-05-24 |
Jumpcode Genomics, Inc. |
Method for target specific RNA transcription of DNA sequences
|
|
US11060088B2
(en)
|
2016-02-12 |
2021-07-13 |
University Of Massachusetts |
Anti-angiogenic miRNA therapeutics for inhibiting corneal neovascularization
|
|
BR112018017125A2
(pt)
|
2016-02-22 |
2018-12-26 |
The University Of North Carolina At Chapel Hill |
vetor aav-idua para tratamento de cegueira associada a mps i
|
|
IL261642B2
(en)
|
2016-03-07 |
2026-01-01 |
Univ Iowa Res Found |
AAV-mediated expression using a synthetic promoter and enhancer
|
|
US11207426B2
(en)
|
2016-04-05 |
2021-12-28 |
University Of Massachusetts |
Compositions and methods for selective inhibition of grainyhead-like protein expression
|
|
US11413356B2
(en)
|
2016-04-15 |
2022-08-16 |
University Of Massachusetts |
Methods and compositions for treating metabolic imbalance
|
|
US10585103B2
(en)
|
2016-04-28 |
2020-03-10 |
The Trustees Of Indiana University |
Methods and compositions for resolving components of a virus preparation
|
|
EP4049683A1
(de)
|
2016-04-29 |
2022-08-31 |
Adverum Biotechnologies, Inc. |
Evasion von neutralisierenden antikörpern durch ein rekombinantes adeno-assoziiertes virus
|
|
EP3448874A4
(de)
|
2016-04-29 |
2020-04-22 |
Voyager Therapeutics, Inc. |
Zusammensetzungen zur behandlung einer erkrankung
|
|
EP3448987A4
(de)
|
2016-04-29 |
2020-05-27 |
Voyager Therapeutics, Inc. |
Zusammensetzungen zur behandlung einer erkrankung
|
|
CR20180589A
(es)
|
2016-05-13 |
2019-02-27 |
4D Molecular Therapeutics Inc |
Cápsulas variantes de virus adenoasociados y métodos de uso de estas
|
|
EP3458589A4
(de)
|
2016-05-18 |
2020-01-01 |
Voyager Therapeutics, Inc. |
Zusammensetzungen und verfahren zur behandlung von morbus huntington
|
|
EP3458588B1
(de)
|
2016-05-18 |
2025-10-29 |
Voyager Therapeutics, Inc. |
Modulatorische polynukleotide
|
|
US12173305B2
(en)
|
2016-05-26 |
2024-12-24 |
University Of Iowa Research Foundation |
cis and trans requirements for terminal resolution of human bocavirus 1
|
|
JP2019517274A
(ja)
|
2016-06-13 |
2019-06-24 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill |
最適化されたcln1遺伝子および発現カセットおよびそれらの使用
|
|
US11882815B2
(en)
|
2016-06-15 |
2024-01-30 |
University Of Massachusetts |
Recombinant adeno-associated viruses for delivering gene editing molecules to embryonic cells
|
|
WO2017221145A1
(en)
|
2016-06-21 |
2017-12-28 |
Bamboo Therapeutics, Inc. |
Optimized mini-dystrophin genes and expression cassettes and their use
|
|
BR112019001344A2
(pt)
|
2016-07-26 |
2019-04-30 |
The University Of North Carolina At Chapel Hill |
tolerância imunológica mediada por vetor no olho
|
|
CA3035522A1
(en)
|
2016-08-30 |
2018-03-08 |
The Regents Of The University Of California |
Methods for biomedical targeting and delivery and devices and systems for practicing the same
|
|
US10457940B2
(en)
|
2016-09-22 |
2019-10-29 |
University Of Massachusetts |
AAV treatment of Huntington's disease
|
|
CN110506119A
(zh)
|
2016-10-13 |
2019-11-26 |
马萨诸塞大学 |
Aav衣壳设计
|
|
EP3528785A4
(de)
|
2016-10-19 |
2020-12-02 |
Adverum Biotechnologies, Inc. |
Modifizierte aav-kaspide und verwendungen davon
|
|
EP3535396A1
(de)
|
2016-11-01 |
2019-09-11 |
Novartis AG |
Verfahren und zusammensetzungen zur verbesserung der genbearbeitung
|
|
WO2018132747A1
(en)
|
2017-01-13 |
2018-07-19 |
University Of Iowa Research Foundation |
Bocaparvovirus small noncoding rna and uses thereof
|
|
WO2018134168A1
(en)
|
2017-01-17 |
2018-07-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of expressing a polynucleotide of interest in the cone photoreceptors
|
|
JP7081767B2
(ja)
*
|
2017-01-30 |
2022-06-07 |
学校法人日本医科大学 |
アデノ随伴ウイルス(aav)キャプシドタンパク質の変異体
|
|
CN110770346B
(zh)
|
2017-03-15 |
2024-01-12 |
北卡罗来纳-查佩尔山大学 |
多倍体腺相关病毒载体及其制备和使用方法
|
|
EP3388520A1
(de)
|
2017-04-11 |
2018-10-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren und pharmazeutische zusammensetzung zur reduzierung der expression von nkcc1 in einer darauf angewiesenen person
|
|
US11752181B2
(en)
|
2017-05-05 |
2023-09-12 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating Huntington's disease
|
|
AU2018261790B2
(en)
|
2017-05-05 |
2024-10-03 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating amyotrophic lateral sclerosis (ALS)
|
|
WO2018208972A1
(en)
|
2017-05-09 |
2018-11-15 |
University Of Massachusetts |
Methods of treating amyotrophic lateral sclerosis (als)
|
|
KR102765034B1
(ko)
|
2017-05-24 |
2025-02-11 |
유니버시타트 아우토노마 데 바르셀로나 |
섬유아세포 성장 인자 21 (fgf21) 코딩 서열을 포함하는 바이러스 발현 컨스트럭트
|
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
|
CA3106446A1
(en)
|
2017-07-13 |
2019-01-17 |
University Of Miami |
Method for managing pain
|
|
EP3654860A1
(de)
|
2017-07-17 |
2020-05-27 |
Voyager Therapeutics, Inc. |
Trajektoriearrayführungssystem
|
|
EP3658577A1
(de)
|
2017-07-27 |
2020-06-03 |
Novartis AG |
Sheddase-resistente trem2-varianten
|
|
CN111448308A
(zh)
|
2017-08-03 |
2020-07-24 |
沃雅戈治疗公司 |
递送aav的组合物和方法
|
|
WO2019040586A1
(en)
*
|
2017-08-25 |
2019-02-28 |
Ovid Therapeutics Inc. |
RECOMBINANT ADENO-ASSOCIATE VECTORS
|
|
EP4218828A3
(de)
|
2017-09-20 |
2023-09-27 |
4D Molecular Therapeutics Inc. |
Kapside mit adeno-assoziierten virenvarianten und verfahren zur verwendung davon
|
|
WO2019060538A1
(en)
|
2017-09-20 |
2019-03-28 |
The Trustees Of Indiana University |
METHODS FOR LIPOPROTEIN RESOLUTION BY MASS SPECTROMETRY
|
|
CA3075643A1
(en)
|
2017-09-22 |
2019-03-28 |
University Of Massachusetts |
Sod1 dual expression vectors and uses thereof
|
|
US20200263199A1
(en)
|
2017-09-29 |
2020-08-20 |
Voyager Therapeutics, Inc. |
Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery
|
|
WO2019079240A1
(en)
|
2017-10-16 |
2019-04-25 |
Voyager Therapeutics, Inc. |
TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
|
|
EP3697908A1
(de)
|
2017-10-16 |
2020-08-26 |
Voyager Therapeutics, Inc. |
Behandlung von amyotropher lateralsklerose (als)
|
|
EP3697448A1
(de)
|
2017-10-20 |
2020-08-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren zur expression eines bestimmten polynukleotids in den zapfen-fotorezeptoren einer person mit subretinaler abgabe einer therapeutisch wirksamen menge eines rekombinanten aav9-vektors
|
|
BR112020008835A2
(pt)
|
2017-11-07 |
2020-10-20 |
The University Of North Carolina At Chapel Hill |
genes de aga otimizados e cassetes de expressão e seu uso
|
|
KR102793696B1
(ko)
|
2017-11-27 |
2025-04-09 |
4디 몰레큘러 테라퓨틱스 아이엔씨. |
아데노-관련 바이러스 변이체 캡시드 및 혈관 신생을 억제하기 위한 용도
|
|
US11232941B2
(en)
|
2018-01-12 |
2022-01-25 |
The Trustees Of Indiana University |
Electrostatic linear ion trap design for charge detection mass spectrometry
|
|
CN111601620A
(zh)
*
|
2018-01-17 |
2020-08-28 |
阿瑞纳斯治疗公司 |
用于21-羟化酶缺乏症的腺相关病毒基因疗法
|
|
EP3746153A4
(de)
|
2018-02-21 |
2021-11-10 |
Alcyone Lifesciences, Inc. |
Systeme und verfahren zur abgabe von flüssigkeiten
|
|
BR112020016699A2
(pt)
|
2018-02-28 |
2020-12-15 |
The University Of North Carolina At Chapel Hill |
Métodos e composições para vetores de vírus de evasão de anticorpos
|
|
SG11202009450SA
(en)
|
2018-04-03 |
2020-10-29 |
Stridebio Inc |
Virus vectors for targeting ophthalmic tissues
|
|
CN112272672A
(zh)
|
2018-04-03 |
2021-01-26 |
斯特里迪比奥公司 |
抗体逃避性病毒载体
|
|
SG11202009451VA
(en)
|
2018-04-03 |
2020-10-29 |
Stridebio Inc |
Antibody-evading virus vectors
|
|
JP7611702B2
(ja)
|
2018-05-06 |
2025-01-10 |
エメンドバイオ インコーポレーテッド |
ヘテロ接合性elane遺伝子の対立遺伝子の差次的ノックアウト
|
|
TW202005978A
(zh)
|
2018-05-14 |
2020-02-01 |
美商拜奧馬林製藥公司 |
新穎肝靶向腺相關病毒載體
|
|
CN112424359A
(zh)
|
2018-05-15 |
2021-02-26 |
沃雅戈治疗公司 |
用于治疗帕金森氏病的组合物和方法
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
AU2019281255B2
(en)
|
2018-06-04 |
2023-01-12 |
The Trustees Of Indiana University |
Ion trap array for high throughput charge detection mass spectrometry
|
|
WO2019236143A1
(en)
|
2018-06-04 |
2019-12-12 |
The Trustees Of Indiana University |
Apparatus and method for calibrating or resetting a charge detector
|
|
JP7398810B2
(ja)
|
2018-06-04 |
2023-12-15 |
ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー |
静電線形イオン・トラップにイオンを捕獲する装置および方法
|
|
US11315780B2
(en)
|
2018-06-04 |
2022-04-26 |
The Trustees Of Indiana University |
Charge detection mass spectrometry with real time analysis and signal optimization
|
|
WO2019236139A1
(en)
|
2018-06-04 |
2019-12-12 |
The Trustees Of Indiana University |
Interface for transporting ions from an atmospheric pressure environment to a low pressure environment
|
|
US12163129B2
(en)
|
2018-06-08 |
2024-12-10 |
University Of Massachusetts |
Antisense oligonucleotides to restore dysferlin protein expression in dysferlinopathy patient cells
|
|
CN119242659A
(zh)
|
2018-06-12 |
2025-01-03 |
北卡罗来纳大学教堂山分校 |
合成嗜肝性腺相关病毒衣壳及其用途
|
|
US12060567B2
(en)
|
2018-06-13 |
2024-08-13 |
Voyager Therapeutics, Inc. |
Engineered untranslated regions (UTR) for AAV production
|
|
FI3814513T3
(fi)
|
2018-06-28 |
2025-05-28 |
Univ North Carolina Chapel Hill |
Optimoidut cln5-geenit ja -ilmentymiskasetit sekä niiden käyttö
|
|
CA3107462A1
(en)
|
2018-07-24 |
2020-01-30 |
Voyager Therapeutics, Inc. |
Systems and methods for producing gene therapy formulations
|
|
IL280300B2
(en)
|
2018-08-10 |
2025-06-01 |
Univ North Carolina Chapel Hill |
Optimized cln7 genes and expression cassettes and their use
|
|
AU2019327386A1
(en)
|
2018-08-27 |
2021-03-18 |
Alcyone Therapeutics, Inc. |
Fluid delivery systems and methods
|
|
WO2020069029A1
(en)
|
2018-09-26 |
2020-04-02 |
Emendobio Inc. |
Novel crispr nucleases
|
|
CN113383010B
(zh)
|
2018-09-28 |
2025-09-09 |
沃雅戈治疗公司 |
具有经工程化改造的启动子的共济蛋白表达构建体及其使用方法
|
|
WO2020072849A1
(en)
|
2018-10-04 |
2020-04-09 |
Voyager Therapeutics, Inc. |
Methods for measuring the titer and potency of viral vector particles
|
|
WO2020072844A1
(en)
|
2018-10-05 |
2020-04-09 |
Voyager Therapeutics, Inc. |
Engineered nucleic acid constructs encoding aav production proteins
|
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
|
JP2022505106A
(ja)
|
2018-10-15 |
2022-01-14 |
ボイジャー セラピューティクス インコーポレイテッド |
バキュロウイルス/Sf9システムにおけるrAAVの大規模産生のための発現ベクター
|
|
BR112021006074A2
(pt)
|
2018-11-05 |
2021-07-20 |
The University Of North Carolina At Chapel Hill |
genes e cassetes de expressão fig4 otimizados e seu uso
|
|
EP3884510A1
(de)
|
2018-11-20 |
2021-09-29 |
The Trustees of Indiana University |
Orbitrap für einzelteilchen-massenspektrometrie
|
|
AU2019392058B2
(en)
|
2018-12-03 |
2024-12-05 |
The Trustees Of Indiana University |
Apparatus and method for simultaneously analyzing multiple ions with an electrostatic linear ion trap
|
|
WO2020132385A1
(en)
|
2018-12-21 |
2020-06-25 |
The University Of North Carolina At Chapel Hill |
Optimized galc genes and expression cassettes and their use
|
|
WO2020163379A1
(en)
|
2019-02-05 |
2020-08-13 |
Emendobio Inc. |
Crispr compositions and methods for promoting gene editing of ribosomal protein s19 (rps19) gene
|
|
WO2020163307A1
(en)
|
2019-02-06 |
2020-08-13 |
Emendobio Inc. |
New engineered high fidelity cas9
|
|
WO2020174369A2
(en)
|
2019-02-25 |
2020-09-03 |
Novartis Ag |
Compositions and methods to treat bietti crystalline dystrophy
|
|
CN113677801A
(zh)
|
2019-02-25 |
2021-11-19 |
诺华股份有限公司 |
治疗bietti晶体营养不良的组合物和方法
|
|
SG11202110146VA
(en)
|
2019-03-21 |
2021-10-28 |
Stridebio Inc |
Recombinant adeno-associated virus vectors
|
|
JP7630176B2
(ja)
|
2019-04-01 |
2025-02-17 |
テナヤ セラピューティクス, インコーポレイテッド |
操作されたカプシドを有するアデノ随伴ウイルス
|
|
CA3136872A1
(en)
|
2019-04-23 |
2020-10-29 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
New adeno-associated virus (aav) variants and uses thereof for gene therapy
|
|
WO2020219527A1
(en)
|
2019-04-23 |
2020-10-29 |
The Trustees Of Indiana University |
Identification of sample subspecies based on particle charge behavior under structural change-inducing sample conditions
|
|
US11981967B2
(en)
|
2019-04-26 |
2024-05-14 |
Sangamo Therapeutics, Inc. |
Engineering AAV
|
|
CA3144654A1
(en)
|
2019-04-29 |
2020-11-05 |
The University Of North Carolina At Chapel Hill |
Optimized sumf1 genes and expression cassettes and their use
|
|
TW202104592A
(zh)
*
|
2019-05-14 |
2021-02-01 |
美商拜奧馬林製藥公司 |
重複投予基因療法載體之方法
|
|
WO2020237130A1
(en)
|
2019-05-22 |
2020-11-26 |
The University Of North Carolina At Chapel Hill |
Ube3a genes and expression cassettes and their use
|
|
CN114989267A
(zh)
*
|
2019-05-24 |
2022-09-02 |
瑞泽恩制药公司 |
经修饰的病毒颗粒和其用途
|
|
CA3144864A1
(en)
|
2019-06-27 |
2020-12-30 |
Pfizer Inc. |
Methods of treating duchenne muscular dystrophy using aav mini-dystrophin gene therapy
|
|
EP3914720B9
(de)
|
2019-07-10 |
2023-09-27 |
Masonic Medical Research Laboratory |
Vgll4 mit ucp-1-cis-regulierendem element und verfahren zu dessen verwendung
|
|
US10801042B1
(en)
|
2019-07-15 |
2020-10-13 |
Vigene Biosciences, Inc. |
Use of ion concentrations to increase the packaging efficiency of recombinant adeno-associated virus
|
|
US10557149B1
(en)
|
2019-07-15 |
2020-02-11 |
Vigene Biosciences, Inc. |
Recombinantly-modified adeno-associated virus helper vectors and their use to improve the packaging efficiency of recombinantly-modified adeno-associated virus
|
|
US10653731B1
(en)
|
2019-07-15 |
2020-05-19 |
Vigene Biosciences Inc. |
Recombinantly-modified adeno-associated virus (rAAV) having improved packaging efficiency
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
|
WO2021053559A1
(en)
|
2019-09-18 |
2021-03-25 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
CN120109003A
(zh)
|
2019-09-25 |
2025-06-06 |
印地安纳大学理事会 |
用于脉冲模式电荷检测质谱法的设备和方法
|
|
GB201913974D0
(en)
|
2019-09-27 |
2019-11-13 |
King S College London |
Vector
|
|
JP7659325B2
(ja)
|
2019-10-10 |
2025-04-09 |
ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー |
粒子を識別、選択、および純化するためのシステムおよび方法
|
|
US20230392163A1
(en)
|
2019-10-17 |
2023-12-07 |
Ginkgo Bioworks Inc. |
Adeno-associated viral vectors for treatment of niemann-pick disease type c
|
|
WO2021126972A1
(en)
|
2019-12-18 |
2021-06-24 |
The Trustees Of Indiana University |
Mass spectrometer with charge measurement arrangement
|
|
JP7607355B2
(ja)
|
2020-02-03 |
2024-12-27 |
ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー |
電荷検出質量分析用信号の時間ドメイン分析
|
|
US20230136699A1
(en)
|
2020-02-28 |
2023-05-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Gene therapy for maple syrup urine disease
|
|
US20230158173A1
(en)
|
2020-03-20 |
2023-05-25 |
University Of Florida Research Foundation, Inc. |
Gene therapy for cockayne syndrome
|
|
EP4100532A4
(de)
|
2020-03-23 |
2024-03-27 |
The University of North Carolina at Chapel Hill |
Aav-naglu-vektoren zur behandlung von mukopolysaccharidose iiib
|
|
EP4132955A2
(de)
|
2020-04-10 |
2023-02-15 |
SOLA Biosciences LLC |
Zusammensetzungen und verfahren zur behandlung von proteinaggregationsstörungen
|
|
DK4100539T3
(da)
|
2020-04-27 |
2026-02-16 |
4D Molecular Therapeutics Inc |
Adenoassocierede varianter, formuleringer og fremgangsmåder til pulmonal indgivelse
|
|
MX2022013288A
(es)
|
2020-04-28 |
2023-02-22 |
Sola Biosciences Llc |
Composiciones y metodos para el tratamiento de proteinopatias por la proteina 43 de union a acido desoxirribonucleico (adn) de respuesta transactiva (tdp-43).
|
|
MX2022013819A
(es)
|
2020-05-05 |
2023-01-30 |
Univ North Carolina Chapel Hill |
Capsides de virus adeno-asociado 5 modificado y usos del mismo.
|
|
WO2021247995A2
(en)
|
2020-06-04 |
2021-12-09 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating neuropathic pain
|
|
EP4161953A1
(de)
|
2020-06-05 |
2023-04-12 |
SOLA Biosciences LLC |
Zusammensetzungen und verfahren zur behandlung von synukleinopathien
|
|
ES3057565T3
(en)
|
2020-07-23 |
2026-03-03 |
Univ North Carolina Chapel Hill |
Optimized slc13a5 genes and expression cassettes and their use
|
|
CN116745409A
(zh)
|
2020-08-19 |
2023-09-12 |
萨雷普塔治疗公司 |
用于治疗雷特综合征的腺相关病毒载体
|
|
WO2022076648A1
(en)
|
2020-10-09 |
2022-04-14 |
Tenaya Therapeutics, Inc. |
Plakophillin-2 gene therapy methods and compositions
|
|
EP4240861A1
(de)
|
2020-11-03 |
2023-09-13 |
Pfizer Inc. |
Verfahren zur reinigung von aav-vektoren durch anionenaustauschchromatografie
|
|
WO2022130172A1
(en)
|
2020-12-15 |
2022-06-23 |
Pfizer Inc. |
Hilic uplc-ms method for separating and analyzing intact adeno-associated virus capsid proteins
|
|
MX2023007612A
(es)
|
2020-12-23 |
2023-07-12 |
Pfizer |
Metodos para purificacion de vectores aav por cromatografia de afinidad.
|
|
TW202242124A
(zh)
|
2021-01-14 |
2022-11-01 |
美商史崔德生物公司 |
靶向t細胞之aav載體
|
|
WO2022208342A1
(en)
|
2021-04-01 |
2022-10-06 |
Pfizer Inc. |
Pharmaceutical compositions containing adeno-associated viral vector
|
|
JP2024515626A
(ja)
|
2021-04-16 |
2024-04-10 |
アスクレピオス バイオファーマシューティカル, インコーポレイテッド |
血液脳関門を横断し低減された液性応答を惹起する合理的ポリプロイドaavビリオン
|
|
EP4329820A1
(de)
|
2021-04-26 |
2024-03-06 |
Alexion Pharma International Operations Limited |
Adeno-assoziierte virale vektorkapside mit verbessertem gewebetropismus
|
|
KR20240014477A
(ko)
|
2021-05-28 |
2024-02-01 |
상하이 레제네리드 테라피즈 컴퍼니 리미티드 |
변이체 캡시드를 갖는 재조합 아데노-연관 바이러스 및 이의 응용
|
|
US12570977B2
(en)
*
|
2021-06-12 |
2026-03-10 |
Mello Biotech Taiwan Co., Ltd. |
mRNA composition and production method for use in anti-viral and anti-cancer vaccines
|
|
EP4359547A1
(de)
|
2021-06-22 |
2024-05-01 |
Pfizer Inc. |
Herstellung eines adeno-assoziierten virusvektors in insektenzellen
|
|
EP4367251A1
(de)
|
2021-07-08 |
2024-05-15 |
Tenaya Therapeutics, Inc. |
Optimierte expressionskassetten für die gentherapie
|
|
EP4384195A2
(de)
|
2021-08-11 |
2024-06-19 |
King's College London |
Zusammensetzungen und verfahren zur verbesserten behandlung von erkrankungen mit einfluss auf das zentrale nervensystem
|
|
US20250042958A1
(en)
|
2021-10-08 |
2025-02-06 |
Sola Biosciences Llc |
Compositions and methods for the treatment of proteopathies
|
|
JP2024537178A
(ja)
|
2021-10-08 |
2024-10-10 |
ソラ・バイオサイエンシズ・エルエルシー |
p53媒介性癌の処置のための組成物および方法
|
|
AU2022368907A1
(en)
|
2021-10-20 |
2024-05-02 |
University Of Copenhagen |
Rejuvenation treatment of age-related white matter loss
|
|
JP2024542015A
(ja)
|
2021-11-02 |
2024-11-13 |
ユニバーシティ オブ ロチェスター |
脳内でのtcf7l2媒介性髄鞘再生
|
|
JP2024540181A
(ja)
|
2021-11-04 |
2024-10-31 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
骨格筋に再標的化されたウイルス粒子
|
|
WO2023114816A1
(en)
|
2021-12-14 |
2023-06-22 |
Neurogene, Inc. |
Recombinant optimized galc constructs and methods for treating galc-associated disorders
|
|
GB202201242D0
(en)
|
2022-01-31 |
2022-03-16 |
Univ Edinburgh |
Recombinant optimized mecp2 cassettes and methods for treating rett syndrome and related disorders
|
|
WO2023150687A1
(en)
|
2022-02-04 |
2023-08-10 |
Ginkgo Bioworks, Inc. |
Recombinant adeno-associated virus vectors, and methods of use thereof
|
|
EP4508062A1
(de)
|
2022-04-11 |
2025-02-19 |
Tenaya Therapeutics, Inc. |
Adeno-assoziiertes virus mit manipuliertem kapsid
|
|
GB202206336D0
(en)
|
2022-04-29 |
2022-06-15 |
Univ Edinburgh |
Recombinant therapeutic FMR1 constructs and methods of treating fragile X syndrome and related disorders
|
|
US20250353883A1
(en)
|
2022-05-06 |
2025-11-20 |
Novartis Ag |
Novel recombinant aav vp2 fusion polypeptides
|
|
CN119604610A
(zh)
|
2022-05-09 |
2025-03-11 |
瑞泽恩制药公司 |
用于体内抗体产生的载体和方法
|
|
WO2024003687A1
(en)
|
2022-06-28 |
2024-01-04 |
Pfizer Inc. |
Nucleic acids encoding acid alpha-glucosidase (gaa) and vectors for gene therapy
|
|
AU2023314923A1
(en)
|
2022-07-29 |
2025-02-27 |
Regeneron Pharmaceuticals, Inc. |
Viral particles retargeted to transferrin receptor 1
|
|
WO2024038365A1
(en)
|
2022-08-16 |
2024-02-22 |
Pfizer Inc. |
Methods for purification of aav vectors by anion exchange chromatography
|
|
EP4619438A2
(de)
|
2022-11-14 |
2025-09-24 |
Regeneron Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur fibroblastenwachstumsfaktorrezeptor-3-vermittelten abgabe an astrozyten
|
|
WO2024124019A2
(en)
|
2022-12-07 |
2024-06-13 |
Ginkgo Bioworks, Inc. |
Aav vectors targeting hematopoietic stem cells
|
|
KR20250134733A
(ko)
|
2022-12-16 |
2025-09-11 |
리제너론 파아마슈티컬스, 인크. |
Aav 입자에 결합하는 항원-결합 분자 및 용도
|
|
WO2024147114A1
(en)
|
2023-01-06 |
2024-07-11 |
Bloomsbury Genetic Therapies Limited |
Compositions and methods for treating parkinson's disease
|
|
EP4658294A2
(de)
|
2023-02-02 |
2025-12-10 |
University of Rochester |
Kompetitiver ersatz von gliazellen
|
|
CN120677178A
(zh)
|
2023-02-13 |
2025-09-19 |
瑞泽恩制药公司 |
用抗人cacng1抗体治疗肌肉相关病症
|
|
WO2024215653A1
(en)
|
2023-04-10 |
2024-10-17 |
Tenaya Therapeutics, Inc. |
Guide rnas, vectors, and virions for targeting mutations in the pln gene
|
|
WO2024215655A1
(en)
|
2023-04-10 |
2024-10-17 |
Tenaya Therapeutics, Inc. |
Cardioprotective bag3 therapies
|
|
AU2024265507A1
(en)
|
2023-05-02 |
2025-10-30 |
Regeneron Pharmaceuticals, Inc. |
Anti-human m-cadherin (cdh15) antibodies, conjugates, and uses thereof for delivery of genetic payloads to muscle cells
|
|
WO2025042428A1
(en)
|
2023-08-18 |
2025-02-27 |
Regeneron Pharmaceuticals, Inc. |
Bispecific antigen-binding molecules and uses thereof
|
|
WO2025082618A1
(en)
|
2023-10-20 |
2025-04-24 |
Fuse Vectors Aps |
In vitro parvovirus capsid manufacturing
|
|
WO2025090427A1
(en)
|
2023-10-23 |
2025-05-01 |
University Of Rochester |
Glial-targeted relief of hyperexcitability in neurodegenerative diseases
|
|
WO2025090858A1
(en)
|
2023-10-27 |
2025-05-01 |
Biogen Ma Inc. |
Methods for identifying aav capsid variants with desired characteristics
|
|
WO2025151796A1
(en)
|
2024-01-11 |
2025-07-17 |
Regeneron Pharmaceuticals, Inc. |
Viral particles retargeted to nervous system tissues
|
|
WO2025160340A2
(en)
|
2024-01-26 |
2025-07-31 |
Regeneron Pharmaceuticals, Inc. |
Combination immunosuppression for inhibiting an immune response and enabling immunogen administration and re-administration
|
|
WO2025184603A2
(en)
|
2024-03-01 |
2025-09-04 |
Regeneron Pharmaceuticals, Inc. |
The use of cd40 inhibitors for inhibiting an immune response and enabling immunogen administration and re-administration
|
|
WO2025250457A1
(en)
|
2024-05-28 |
2025-12-04 |
University Of Rochester |
Enhanced brain transduction by gene therapeutics
|
|
WO2025255452A2
(en)
|
2024-06-07 |
2025-12-11 |
Regeneron Pharmaceuticals, Inc. |
Antigen-binding molecules that bind to aav particles and uses thereof
|
|
WO2026017965A1
(en)
|
2024-07-19 |
2026-01-22 |
The University Court Of The University Of Edinburgh |
Recombinant therapeutic fxn constructs and methods of treating friedreich ataxia and related conditions
|
|
WO2026025058A1
(en)
|
2024-07-25 |
2026-01-29 |
Regeneron Pharmaceuticals, Inc. |
Aav viral particles retargeted to egfr-expressing cancer cells
|
|
WO2026039325A2
(en)
|
2024-08-12 |
2026-02-19 |
Regeneron Pharmaceuticals, Inc. |
Modified mtm1 genes and uses thereof
|