ATE404588T1 - Verfahren zur herstellung von chondroitinsulfaten aus k4-polysaccharid und so hergestellte produkte - Google Patents

Verfahren zur herstellung von chondroitinsulfaten aus k4-polysaccharid und so hergestellte produkte

Info

Publication number
ATE404588T1
ATE404588T1 AT02023351T AT02023351T ATE404588T1 AT E404588 T1 ATE404588 T1 AT E404588T1 AT 02023351 T AT02023351 T AT 02023351T AT 02023351 T AT02023351 T AT 02023351T AT E404588 T1 ATE404588 T1 AT E404588T1
Authority
AT
Austria
Prior art keywords
polysaccharide
products produced
producing chondroitin
chondroitin sulphates
sulphates
Prior art date
Application number
AT02023351T
Other languages
English (en)
Inventor
Giorgio Zoppetti
Pasqua Oreste
Original Assignee
Ibsa Inst Biochimique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ibsa Inst Biochimique Sa filed Critical Ibsa Inst Biochimique Sa
Application granted granted Critical
Publication of ATE404588T1 publication Critical patent/ATE404588T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02023351T 2001-10-22 2002-10-18 Verfahren zur herstellung von chondroitinsulfaten aus k4-polysaccharid und so hergestellte produkte ATE404588T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001MI002200A ITMI20012200A1 (it) 2001-10-22 2001-10-22 Processo per la preparazione di condroitin solfati dal polisaccaride k4 e prodotti ottenuti

Publications (1)

Publication Number Publication Date
ATE404588T1 true ATE404588T1 (de) 2008-08-15

Family

ID=11448534

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02023351T ATE404588T1 (de) 2001-10-22 2002-10-18 Verfahren zur herstellung von chondroitinsulfaten aus k4-polysaccharid und so hergestellte produkte

Country Status (7)

Country Link
US (1) US6777398B2 (de)
EP (1) EP1304338B1 (de)
AT (1) ATE404588T1 (de)
CA (1) CA2408681A1 (de)
DE (1) DE60228184D1 (de)
ES (1) ES2312519T3 (de)
IT (1) ITMI20012200A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030104601A1 (en) * 1999-04-01 2003-06-05 Deangelis Paul L. Chondroitin synthase gene and methods of making and using same
US7223571B2 (en) 1998-04-02 2007-05-29 The Board Of Regents Of The Universtiy Of Oklahoma Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US20080108110A1 (en) * 1998-04-02 2008-05-08 Deangelis Paul L Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US20060188966A1 (en) 1998-04-02 2006-08-24 Deangelis Paul L Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same
US7642071B2 (en) 1999-04-01 2010-01-05 The Board Of Regents Of The University Of Oklahoma Methods of expressing gram-negative glycosaminoglycan synthase genes in gram-positive hosts
ITMI20032498A1 (it) 2003-12-17 2005-06-18 Pasqua Anna Oreste Polisaccaridi antitrombotici a basso peso molecolare e
ITMI20010397A1 (it) * 2001-02-27 2002-08-27 Giorgio Zoppetti Derivati altamente n,o-solfatati del polisaccaride k5 e loro preparazione
US8513407B2 (en) * 2002-06-18 2013-08-20 Glycores 2000 S.R.L. Process for the preparation of N-acyl-(epi)K5-amine-O-sulfate-derivatives and products thus obtained
PL375088A1 (en) * 2002-06-18 2005-11-14 Glycores 2000 S.R.L. Epimerized derivatives of k5 polysaccharide with a very high degree of sulfation
PL2296670T3 (pl) 2008-05-13 2013-07-31 Apharm Srl Doustne zastosowanie glikozaminoglikanu i kompozycje
US9109243B2 (en) 2008-06-04 2015-08-18 Amano Enzyme Usa, Ltd. Microbial-derived chondroitin sulfate
IT1394311B1 (it) 2009-05-25 2012-06-06 Altergon Sa Produzione biotecnologica di condroitina
ITMI20110505A1 (it) 2011-03-29 2012-09-30 Altergon Sa Processo per la preparazione di condroitine solfatate in posizione 3 sull'acido glucuronico
AU2012252415B2 (en) * 2011-05-12 2016-11-24 Gnosis S.P.A. "Biotechnological sulphated chondroitin sulphate at position 4 or 6 on the same polysaccharide chain, and process for the preparation thereof"
ITMI20120136A1 (it) * 2012-02-02 2013-08-03 Gnosis Spa Condroitin solfato biotecnologico a basso peso molecolare solfatato in posizione 4 o 6 sulla stessa catena polisaccaridica dotato di attivita' antiinfiammatoria e antiartritica e procedimento per la sua preparazione
ITMI20110829A1 (it) 2011-05-12 2012-11-13 Gnosis Spa Condroitin solfato biotecnologico solfatato in posizione 4 o 6 sulla stessa catena polisaccaridica e procedimento per la sua preparazione
PL2710043T3 (pl) * 2011-05-20 2016-11-30 Podobny do rekiniego siarczan chondroityny oraz sposób jego wytwarzania
US8664196B2 (en) 2011-05-20 2014-03-04 Gnosis S.P.A. Shark-like chondroitin sulphate and process for the preparation thereof
CN102618597A (zh) * 2012-04-06 2012-08-01 江南大学 大肠杆菌工程菌及其生产软骨素的方法
ITMI20120880A1 (it) 2012-05-22 2013-11-23 Gnosis Spa Condroitin 6-solfato biotecnologico a basso peso molecolare dotato di attivita' antiinfiammatoria e antiartritica e suo uso nel trattamento e nella prevenzione dell'osteoartrite
ITMI20120896A1 (it) 2012-05-23 2013-11-24 Bongulielmi Reto Condroitina per uso in medicina
ITMI20121316A1 (it) 2012-07-27 2014-01-28 Altergon Sa Complessi di condroitina ad assorbimento transcutaneo
ITMI20130117A1 (it) 2013-01-25 2014-07-26 Gnosis Spa Composizioni comprendenti condroitin solfato, enzimi proteolitici e composti sulfidrilati capaci di migliorare la biodisponibilita' del condroitin solfato
CN104163877B (zh) * 2014-08-26 2016-05-18 淮安麦德森制药有限公司 硫酸软骨素的制备方法
US11116786B2 (en) 2015-10-01 2021-09-14 Apharm S.R.L. Combination of glycosaminoglycans and an antacid agent and compositions thereof
CN108484795B (zh) * 2018-04-28 2021-02-09 山东第一医科大学第二附属医院 硫酸软骨素锂及其制备方法和应用
CN111662394B (zh) * 2019-03-05 2022-11-04 中国医学科学院药物研究所 硫酸软骨素多糖半合成制备方法和应用
IT202000013633A1 (it) * 2020-06-08 2021-12-08 Vivatis Pharma Gmbh Processo di estrazione di una condroitina solfato da un fungo, una condroitina solfato di origine vegetale e suo uso
CN115353574B (zh) * 2022-09-06 2023-06-13 福建省深蓝生物科技有限公司 高硫酸化度的硫酸软骨素cs-e及其提取方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3895107A (en) * 1970-04-15 1975-07-15 Morrison L M CSA and CSC in man and mammals to inhibit atherosclerosis and the recurrence of cardiovascular incidents in atherosclerotic mammals
US4302577A (en) * 1979-10-05 1981-11-24 Biomed Research Inc. Process for preparing CSA or CSC
IT1289613B1 (it) * 1997-02-07 1998-10-15 Inalco Spa Polisaccaridi batterici o-solfatati
ITMI991465A1 (it) 1999-07-02 2001-01-02 Inalco Spa Processo per la preparazione dei polisaccaridi k4 e k5 da escherichiacoli

Also Published As

Publication number Publication date
DE60228184D1 (de) 2008-09-25
ITMI20012200A1 (it) 2003-04-22
CA2408681A1 (en) 2003-04-22
US6777398B2 (en) 2004-08-17
EP1304338B1 (de) 2008-08-13
EP1304338A1 (de) 2003-04-23
ES2312519T3 (es) 2009-03-01
US20030100534A1 (en) 2003-05-29

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