ATE404695T1 - Einfache katalytische dna-biosensoren für ionen auf grundlage von farbveränderungen - Google Patents
Einfache katalytische dna-biosensoren für ionen auf grundlage von farbveränderungenInfo
- Publication number
- ATE404695T1 ATE404695T1 AT03731042T AT03731042T ATE404695T1 AT E404695 T1 ATE404695 T1 AT E404695T1 AT 03731042 T AT03731042 T AT 03731042T AT 03731042 T AT03731042 T AT 03731042T AT E404695 T1 ATE404695 T1 AT E404695T1
- Authority
- AT
- Austria
- Prior art keywords
- color changes
- ions based
- catalytic dna
- simple catalytic
- dna biosensors
- Prior art date
Links
- 108091027757 Deoxyribozyme Proteins 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/144,679 US7534560B2 (en) | 2002-05-10 | 2002-05-10 | Simple catalytic DNA biosensors for ions based on color changes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE404695T1 true ATE404695T1 (de) | 2008-08-15 |
Family
ID=29418522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03731042T ATE404695T1 (de) | 2002-05-10 | 2003-04-24 | Einfache katalytische dna-biosensoren für ionen auf grundlage von farbveränderungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7534560B2 (de) |
| EP (1) | EP1504018B1 (de) |
| AT (1) | ATE404695T1 (de) |
| AU (1) | AU2003241311A1 (de) |
| CA (1) | CA2482689A1 (de) |
| DE (1) | DE60322880D1 (de) |
| WO (1) | WO2003094838A2 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6706474B1 (en) * | 2000-06-27 | 2004-03-16 | Board Of Trustees Of The University Of Illinois | Nucleic acid enzyme biosensors for ions |
| US7534560B2 (en) | 2002-05-10 | 2009-05-19 | The Board Of Trustees Of The University Of Illinois | Simple catalytic DNA biosensors for ions based on color changes |
| US6890719B2 (en) * | 2002-05-10 | 2005-05-10 | The Board Of Trustess Of The University Of Illinois | Fluorescence based biosensor |
| US7612185B2 (en) * | 2003-03-07 | 2009-11-03 | The Board Of Trustees Of The University Of Illinois | Nucleic acid biosensors |
| EP1689361A4 (de) | 2003-12-02 | 2009-06-17 | 3M Innovative Properties Co | Therapeutische kombinationen und verfahren mit irm-verbindungen |
| US7485419B2 (en) * | 2004-01-13 | 2009-02-03 | The Board Of Trustees Of The University Of Illinois | Biosensors based on directed assembly of particles |
| WO2005073405A2 (en) * | 2004-01-29 | 2005-08-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Catalytic polynucleotide and its use for determination of analytes |
| US20060094026A1 (en) * | 2004-11-03 | 2006-05-04 | Yi Lu | Nucleic acid enzyme light-up sensor utilizing invasive DNA |
| US20060166222A1 (en) * | 2005-01-21 | 2006-07-27 | Yi Lu | Nucleic acid enzyme ligation sensor |
| US20070072205A1 (en) * | 2005-06-09 | 2007-03-29 | Yi Lu | Nanomaterial error correction |
| US7892734B2 (en) * | 2005-08-11 | 2011-02-22 | The Board Of Trustees Of The University Of Illinois | Aptamer based colorimetric sensor systems |
| US7799554B2 (en) * | 2006-03-16 | 2010-09-21 | The Board Of Trustees Of The University Of Illinois | Lateral flow devices |
| US20140024818A1 (en) * | 2006-11-14 | 2014-01-23 | Yi Lu | Alignment of nanomaterials and micromaterials |
| US8415461B2 (en) * | 2007-01-19 | 2013-04-09 | The Board Of Trustees Of The University Of Illinois | Amphiphilic substances and functionalized lipid vesicles including the same |
| US8058415B2 (en) | 2007-04-24 | 2011-11-15 | The Board Of Trustees Of The University Of Illinois | Aptamer- and nucleic acid enzyme-based systems for simultaneous detection of multiple analytes |
| WO2009012309A2 (en) * | 2007-07-16 | 2009-01-22 | The Board Of Trustees Of The University Of Illinois | Nucleic acid based fluorescent sensor for divalent copper ion detection |
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| WO2009045632A2 (en) | 2007-08-10 | 2009-04-09 | The Board Of Trustees Of The University Of Illinois | Nucleic acid based fluorescent sensor for mercury detection |
| US20100105039A1 (en) * | 2008-06-03 | 2010-04-29 | Yi Lu | Label-free colorimetric detection |
| US8062893B2 (en) | 2008-10-10 | 2011-11-22 | The Board Of Trustees Of The University Of Illinois | Fluorescent sensor for mercury |
| US8530158B2 (en) * | 2010-05-10 | 2013-09-10 | Life Technologies Corporation | System and method for processing a biological sample |
| CA2800257C (en) | 2010-05-26 | 2019-03-05 | The Board Of Trustees Of The University Of Illinois | Personal glucose meters for detection and quantification of a broad range of analytes |
| US9000401B2 (en) | 2010-07-07 | 2015-04-07 | Institut National D'optique | Fiber optic radiochromic dosimeter probe and method to make the same |
| US8815156B2 (en) | 2010-07-19 | 2014-08-26 | Andalyze, Inc. | Sensor housing and reagent chemistry |
| US8933210B2 (en) | 2010-10-06 | 2015-01-13 | The Board Of Trustees Of The University Of Illinois | Label-free functional nucleic acid sensors for detecting target agents |
| EP2802862B1 (de) * | 2012-01-11 | 2021-03-10 | The Regents of The University of California | Verfahren für den nachweis von quecksilber mittels lokalisierter oberflächenplasmonresonanz |
| WO2014165659A2 (en) | 2013-04-03 | 2014-10-09 | University Of Massachusetts | An electrochemical tongue |
| ES2743458T5 (es) | 2014-08-08 | 2023-06-08 | Us Health | Eliminación fotocontrolada de dianas in vitro e in vivo |
| JP6701338B2 (ja) | 2015-08-10 | 2020-05-27 | エッセンリックス コーポレーション | ステップが簡略化され、試料が少なく、スピードアップし、使いやすい、生化学的/化学的なアッセイ装置及び方法 |
| US10359412B2 (en) | 2016-09-01 | 2019-07-23 | Schlumberger Technology Corporation | Systems and methods for detection of mercury in hydrocarbon-containing fluids using optical analysis of slug flow |
| US11331019B2 (en) | 2017-08-07 | 2022-05-17 | The Research Foundation For The State University Of New York | Nanoparticle sensor having a nanofibrous membrane scaffold |
| US11648551B2 (en) | 2017-12-12 | 2023-05-16 | Essenlix Corporation | Sample manipulation and assay with rapid temperature change |
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| WO2020177059A1 (en) * | 2019-03-04 | 2020-09-10 | Nano And Advanced Materials Institute Limited | System and method for detecting heavy metals and bacteria in an analyte |
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| CN116004766A (zh) * | 2022-12-19 | 2023-04-25 | 中国科学院生态环境研究中心 | 基于脱氧核酶微量热泳分析目标物的探针和方法 |
| WO2026055211A2 (en) | 2024-09-04 | 2026-03-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Photoactivatable dye compounds for conjugate formation and methods of making and using the same |
Family Cites Families (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0121970A1 (de) | 1983-04-07 | 1984-10-17 | Daisy Systems Holland B.V. | Vorrichtung zur Befestigung eines Typenrades in einem Typenraddrucker und Typenrad |
| US4703017C1 (en) | 1984-02-14 | 2001-12-04 | Becton Dickinson Co | Solid phase assay with visual readout |
| ATE195022T1 (de) | 1987-04-27 | 2000-08-15 | Unilever Nv | Spezifische bindungstestverfahren |
| US4855240A (en) | 1987-05-13 | 1989-08-08 | Becton Dickinson And Company | Solid phase assay employing capillary flow |
| AU2684488A (en) | 1988-06-27 | 1990-01-04 | Carter-Wallace, Inc. | Test device and method for colored particle immunoassay |
| US6040138A (en) * | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US5472881A (en) * | 1992-11-12 | 1995-12-05 | University Of Utah Research Foundation | Thiol labeling of DNA for attachment to gold surfaces |
| US5459040A (en) * | 1993-11-22 | 1995-10-17 | The Regents Of The University Of California | Enzyme amplified, complex linked, competitive and non-competitive assays for the detection of metal ions |
| US5631148A (en) | 1994-04-22 | 1997-05-20 | Chiron Corporation | Ribozymes with product ejection by strand displacement |
| US5580967A (en) * | 1994-05-13 | 1996-12-03 | The Scripps Research Institute | Optimized catalytic DNA-cleaving ribozymes |
| WO1998049346A1 (en) | 1997-04-29 | 1998-11-05 | The Scripps Research Institute | Enzymatic dna molecules |
| US5807718A (en) * | 1994-12-02 | 1998-09-15 | The Scripps Research Institute | Enzymatic DNA molecules |
| US5663064A (en) * | 1995-01-13 | 1997-09-02 | University Of Vermont | Ribozymes with RNA protein binding site |
| US5593835A (en) * | 1995-05-12 | 1997-01-14 | President And Fellows Of Harvard College | Methods and kits for RNA binding compounds |
| US5910408A (en) | 1995-06-07 | 1999-06-08 | The General Hospital Corporation | Catalytic DNA having ligase activity |
| US5989813A (en) * | 1995-07-13 | 1999-11-23 | Molecular Innovations, Inc. | Detection of amplified nucleic acid sequences using bifunctional haptenization and dyed microparticles |
| WO1997009342A1 (en) | 1995-09-08 | 1997-03-13 | Scriptgen Pharmaceuticals, Inc. | Screen for compounds with affinity for rna |
| US5807967A (en) * | 1996-03-21 | 1998-09-15 | The United States Of America As Represented By The Secretary Of The Navy | Fluoroaliphatic cyanate resins for low dielectric applications |
| US6361944B1 (en) * | 1996-07-29 | 2002-03-26 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| EP1818417B1 (de) | 1996-07-29 | 2014-02-12 | Nanosphere, Inc. | Nanopartikel mit angehängten Oligonukleotiden und ihre Verwendungen |
| WO1998027104A1 (en) | 1996-12-19 | 1998-06-25 | Yale University | Bioreactive allosteric polynucleotides |
| US6331392B1 (en) | 1997-03-05 | 2001-12-18 | Anadys Pharmaceutical, Inc. | Screen employing fluorescence anisotropy to identify compounds with affinity for nucleic acids |
| EP1015889A1 (de) | 1997-09-12 | 2000-07-05 | Genelabs Technologies, Inc. | Dsrna/dsrna-bindung- proteine-verfahren und zusammensetsungen |
| US6117643A (en) | 1997-11-25 | 2000-09-12 | Ut Battelle, Llc | Bioluminescent bioreporter integrated circuit |
| DE19811618C1 (de) | 1998-03-17 | 2000-08-31 | Andreas Jenne | Ribozym codierende DNA und ein Oligonucleotidsubstrat enthaltende Zusammensetzung und Verfahren zur Messung von Transkriptionsraten |
| US6287765B1 (en) | 1998-05-20 | 2001-09-11 | Molecular Machines, Inc. | Methods for detecting and identifying single molecules |
| US6573045B1 (en) | 1998-06-05 | 2003-06-03 | Ribotargets, Ltd. | Methods and kits for discovery of RNA-binding compounds |
| US6541617B1 (en) * | 1998-10-27 | 2003-04-01 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
| CA2348779A1 (en) | 1998-11-03 | 2000-05-11 | Yale University | Multidomain polynucleotide molecular sensors |
| JP2000214165A (ja) * | 1999-01-22 | 2000-08-04 | Fuji Photo Film Co Ltd | 均一系酵素免疫分析方法 |
| US6110462A (en) * | 1999-03-03 | 2000-08-29 | The Scripps Research Institute | Enzymatic DNA molecules that contain modified nucleotides |
| DE19915141C2 (de) | 1999-03-26 | 2002-11-21 | Artus Ges Fuer Molekularbiolog | Detektion von Nucleinsäure-Amplifikaten |
| CA2376623C (en) | 1999-06-25 | 2011-04-19 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| AU7737300A (en) | 1999-09-30 | 2001-04-30 | Yale University | Dna-cleaving rnase p rna |
| US6355225B1 (en) | 1999-10-05 | 2002-03-12 | Wm. Marsh Rice University Tda Research, Inc. | Fullerene contrast agent for magnetic resonance imaging and spectroscopy |
| JP3463098B2 (ja) | 1999-10-08 | 2003-11-05 | 独立行政法人産業技術総合研究所 | モジュレートアプタマー及びこれを用いた標的タンパク質の検出方法 |
| DE50001665D1 (de) | 1999-10-12 | 2003-05-08 | Connex Ges Zur Optimierung Von | Verbessertes verfahren zum nachweis von säure-resistenten bakterien der gattung helicobacter im stuhl |
| US6316194B1 (en) | 1999-12-16 | 2001-11-13 | Ribotargets | Methods and kits for discovery of RNA-binding antimicrobials |
| EP1294930B1 (de) | 2000-01-13 | 2011-03-30 | Nanosphere, Inc. | Nanopartikel an denen oligonukleotide gebunden sind und deren verwendungen |
| US6316205B1 (en) | 2000-01-28 | 2001-11-13 | Genelabs Diagnostics Pte Ltd. | Assay devices and methods of analyte detection |
| EP1301625B1 (de) | 2000-03-28 | 2010-11-03 | Nanosphere, Inc. | Nanopartikel mit gebundenen oligonukleotiden und verwendungen derselben |
| US20040126882A1 (en) * | 2000-06-15 | 2004-07-01 | Ellington Andrew D | Regulatable, catalytically active nucleic acids |
| US6706474B1 (en) | 2000-06-27 | 2004-03-16 | Board Of Trustees Of The University Of Illinois | Nucleic acid enzyme biosensors for ions |
| AU2001290965A1 (en) | 2000-09-13 | 2002-03-26 | Archemix Corporation | Target activated nucleic acid biosensor and methods of using same |
| AU2002320058A1 (en) | 2001-06-06 | 2002-12-16 | The General Hspital Corporation | Magnetic-nanoparticle conjugates and methods of use |
| US20030219422A1 (en) | 2001-11-15 | 2003-11-27 | Noxxon Pharma Ag | Allosteric ribozymes and uses thereof |
| US20050089864A1 (en) | 2002-01-22 | 2005-04-28 | Yingfu Li | Signalling aptamer complexes |
| JP2005517409A (ja) | 2002-02-15 | 2005-06-16 | マクマスター ユニヴァーシティー | デオキシリボザイム |
| US20040018515A1 (en) * | 2002-04-03 | 2004-01-29 | Diener John L. | Compositions selective for adenosine diphosphate and methods of using same |
| US7534560B2 (en) | 2002-05-10 | 2009-05-19 | The Board Of Trustees Of The University Of Illinois | Simple catalytic DNA biosensors for ions based on color changes |
| US6890719B2 (en) * | 2002-05-10 | 2005-05-10 | The Board Of Trustess Of The University Of Illinois | Fluorescence based biosensor |
| US7612185B2 (en) * | 2003-03-07 | 2009-11-03 | The Board Of Trustees Of The University Of Illinois | Nucleic acid biosensors |
| US20050136500A1 (en) | 2003-12-19 | 2005-06-23 | Kimberly-Clark Worldwide; Inc. | Flow-through assay devices |
| US7485419B2 (en) | 2004-01-13 | 2009-02-03 | The Board Of Trustees Of The University Of Illinois | Biosensors based on directed assembly of particles |
| JP2007530946A (ja) | 2004-03-23 | 2007-11-01 | クイデル コーポレイション | ハイブリッド相ラテラルフロー・アッセイ |
| US20060019406A1 (en) | 2004-07-23 | 2006-01-26 | Ning Wei | Lateral flow device for the detection of large pathogens |
| US20060094026A1 (en) | 2004-11-03 | 2006-05-04 | Yi Lu | Nucleic acid enzyme light-up sensor utilizing invasive DNA |
| DE102004053918B4 (de) | 2004-11-05 | 2007-06-14 | Analyticon Biotechnologies Ag | Aptamerbasiertes Testsystem |
| US20060166222A1 (en) | 2005-01-21 | 2006-07-27 | Yi Lu | Nucleic acid enzyme ligation sensor |
| US7892734B2 (en) | 2005-08-11 | 2011-02-22 | The Board Of Trustees Of The University Of Illinois | Aptamer based colorimetric sensor systems |
| US7799554B2 (en) * | 2006-03-16 | 2010-09-21 | The Board Of Trustees Of The University Of Illinois | Lateral flow devices |
| US8415461B2 (en) | 2007-01-19 | 2013-04-09 | The Board Of Trustees Of The University Of Illinois | Amphiphilic substances and functionalized lipid vesicles including the same |
-
2002
- 2002-05-10 US US10/144,679 patent/US7534560B2/en not_active Expired - Lifetime
-
2003
- 2003-04-24 CA CA002482689A patent/CA2482689A1/en not_active Abandoned
- 2003-04-24 AU AU2003241311A patent/AU2003241311A1/en not_active Abandoned
- 2003-04-24 AT AT03731042T patent/ATE404695T1/de not_active IP Right Cessation
- 2003-04-24 WO PCT/US2003/012576 patent/WO2003094838A2/en not_active Ceased
- 2003-04-24 EP EP03731042A patent/EP1504018B1/de not_active Expired - Lifetime
- 2003-04-24 DE DE60322880T patent/DE60322880D1/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003241311A8 (en) | 2003-11-11 |
| WO2003094838A3 (en) | 2004-10-21 |
| AU2003241311A1 (en) | 2003-11-11 |
| US7534560B2 (en) | 2009-05-19 |
| CA2482689A1 (en) | 2003-11-20 |
| EP1504018A4 (de) | 2006-08-09 |
| EP1504018A2 (de) | 2005-02-09 |
| WO2003094838A2 (en) | 2003-11-20 |
| DE60322880D1 (de) | 2008-09-25 |
| US20030215810A1 (en) | 2003-11-20 |
| EP1504018B1 (de) | 2008-08-13 |
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