ATE412000T1 - Verfahren zur herstellung von n-demethylolanzapin - Google Patents

Verfahren zur herstellung von n-demethylolanzapin

Info

Publication number: ATE412000T1
Authority: AT; Austria
Prior art keywords: demethylolanzapine; olanzapine; producing; piperazine; benzodiazepine
Prior art date: 2004-11-22

Application number

AT05810971T

Other languages

English (en)

Inventor

Tomasz Stawinski

Justyna Rechnio

Zbigniew Majka

Original Assignee

Adamed Sp Zoo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-22

Filing date

2005-11-15

Publication date

2008-11-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35645631&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE412000(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-11-15 Application filed by Adamed Sp Zoo filed Critical Adamed Sp Zoo

2008-11-15 Application granted granted Critical

2008-11-15 Publication of ATE412000T1 publication Critical patent/ATE412000T1/de

Links

FHPIXVHJEIZKJW-UHFFFAOYSA-N 4'-N-desmethylolanzapine Chemical compound S1C(C)=CC2=C1NC1=CC=CC=C1N=C2N1CCNCC1 FHPIXVHJEIZKJW-UHFFFAOYSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 4
KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 abstract 2
229960005017 olanzapine Drugs 0.000 abstract 2
230000000561 anti-psychotic effect Effects 0.000 abstract 1
229940049706 benzodiazepine Drugs 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000007069 methylation reaction Methods 0.000 abstract 1
150000007522 mineralic acids Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Hydrogenated Pyridines (AREA)
Cephalosporin Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT05810971T 2004-11-22 2005-11-15 Verfahren zur herstellung von n-demethylolanzapin ATE412000T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PL371307A PL198589B1 (pl)	2004-11-22	2004-11-22	Sposób wytwarzania N-demetyloolanzapiny

Publications (1)

Publication Number	Publication Date
ATE412000T1 true ATE412000T1 (de)	2008-11-15

Family

ID=35645631

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05810971T ATE412000T1 (de)	2004-11-22	2005-11-15	Verfahren zur herstellung von n-demethylolanzapin

Country Status (10)

Country	Link
EP (2)	EP1814886B1 (de)
CN (1)	CN101061124B (de)
AT (1)	ATE412000T1 (de)
DE (1)	DE602005010606D1 (de)
ES (1)	ES2315928T3 (de)
NO (1)	NO20073165L (de)
PL (1)	PL198589B1 (de)
PT (1)	PT1814886E (de)
SI (1)	SI1814886T1 (de)
WO (1)	WO2006053870A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL395468A1 (pl)	2011-06-29	2013-01-07	Adamed Spólka Z Ograniczona Odpowiedzialnoscia	Zwiazki amidoalkilopiperazynylowe do leczenia chorób osrodkowego ukladu nerwowego
CN102924470B (zh) *	2011-08-31	2014-12-03	江苏豪森药业股份有限公司	新颖的奥氮平的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9009229D0 (en)	1990-04-25	1990-06-20	Lilly Industries Ltd	Pharmaceutical compounds
CA2351718A1 (en)	1998-11-23	2000-06-02	Sepracor Inc.	Desmethylolanzapine compositions and methods
CN1420117A (zh) *	2001-11-16	2003-05-28	连云港豪森制药有限公司	一种制备奥氮平的方法
PL199016B1 (pl)	2002-06-20	2008-08-29	Adamed Sp Z Oo	Sposób wytwarzania olanzapiny
AU2003243143A1 (en) *	2003-03-20	2004-11-19	Watson Pharmaceuticals, Inc.	2-methyl-thieno-benzodiazepine process

2004
- 2004-11-22 PL PL371307A patent/PL198589B1/pl unknown
2005
- 2005-11-15 SI SI200530530T patent/SI1814886T1/sl unknown
- 2005-11-15 CN CN2005800399627A patent/CN101061124B/zh not_active Expired - Fee Related
- 2005-11-15 ES ES05810971T patent/ES2315928T3/es not_active Expired - Lifetime
- 2005-11-15 PT PT05810971T patent/PT1814886E/pt unknown
- 2005-11-15 WO PCT/EP2005/055981 patent/WO2006053870A1/en not_active Ceased
- 2005-11-15 DE DE602005010606T patent/DE602005010606D1/de not_active Expired - Lifetime
- 2005-11-15 EP EP05810971A patent/EP1814886B1/de not_active Expired - Lifetime
- 2005-11-15 EP EP08161324.2A patent/EP1988092B1/de not_active Ceased
- 2005-11-15 AT AT05810971T patent/ATE412000T1/de not_active IP Right Cessation
2007
- 2007-06-22 NO NO20073165A patent/NO20073165L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE602005010606D1 (de)	2008-12-04
EP1988092A1 (de)	2008-11-05
SI1814886T1 (sl)	2009-04-30
CN101061124A (zh)	2007-10-24
EP1814886B1 (de)	2008-10-22
WO2006053870A1 (en)	2006-05-26
PT1814886E (pt)	2008-11-04
ES2315928T3 (es)	2009-04-01
EP1988092B1 (de)	2013-11-27
EP1814886A1 (de)	2007-08-08
NO20073165L (no)	2007-06-22
PL371307A1 (pl)	2006-05-29
CN101061124B (zh)	2010-07-28
PL198589B1 (pl)	2008-06-30

Similar Documents

Publication	Publication Date	Title
DE60006298D1 (de)	2003-12-11	Verfahren zur Herstellung von Kohlendioxid
DE602005016292D1 (de)	2009-10-08	Verfahren zur herstellung von glatiramer
DE60336226D1 (de)	2011-04-14	Verfahren zur herstellung von olanzapin form i
DE60321626D1 (de)	2008-07-31	Verfahren zur Herstellung von Acrylsäure
DE502004005626D1 (de)	2008-01-10	Verfahren zur herstellung von organoacylphosphiten
DE602004025267D1 (de)	2010-03-11	Verfahren zur herstellung form i von (s)-(+)- clopidogrelbisulfat
DE60202261D1 (de)	2005-01-20	Verfahren zur herstellung von mesylaten von piperazinderivaten
DE60100217D1 (de)	2003-06-05	Verfahren zur Herstellung von hochkonzentrierten Kohlendioxid
ATE371660T1 (de)	2007-09-15	Verfahren zur herstellung von olanzapine und ein zwischenprodukt dafür
DE60217414D1 (de)	2007-02-15	Verfahren zur Herstellung von Alpha-Hydroxycarbonsäure Amiden
ATE359287T1 (de)	2007-05-15	Ein verfahren zur herstellung von clopidogrel
ATE412000T1 (de)	2008-11-15	Verfahren zur herstellung von n-demethylolanzapin
ATE424892T1 (de)	2009-03-15	Verfahren zur herstellung von derivaten des 4a,5, 9,10,11,12-hexahydrobenzofuro ä3a,3,2üä 2 ü- benzazepins
DE602005024566D1 (de)	2010-12-16	Verfahren zur herstellung von 2-amino-5-iodobenzoesäure
DE60318444D1 (de)	2008-02-14	Verfahren zur herstellung von nevirapin
DE602005003678D1 (de)	2008-01-17	Gemischtes olanzapinsolvat, verfahren zu dessen herstellung und verfahren zur herstellung von olanzapin-form i daraus
DE502004009156D1 (de)	2009-04-23	Verfahren zur herstellung von mit phosphonsäureester modifizierten organosiloxanen
DE502004002234D1 (de)	2007-01-18	Verfahren zur herstellung der enantiomeren formen von cis-konfigurierten 1,3-cyclohexandiol-derivaten
DE10082578D2 (de)	2002-11-21	Verfahren zur Herstellung von regelmäßigen Nanostrukturen
ATE466010T1 (de)	2010-05-15	Verfahren zur herstellung von candesartan
DE602004029787D1 (de)	2010-12-09	Verfahren zur herstellung von 5-iodo-2-methylbenzoesäure
DE60005252D1 (de)	2003-10-23	Verfahren zur Herstellung von Malononitril
DE502004011536D1 (de)	2010-09-23	verfahren zur herstellung von bengamide-derivaten
DE502005009149D1 (de)	2010-04-15	Verfahren zur herstellung von blausäure
DE502005002040D1 (de)	2008-01-03	Kontinuierliches verfahren zur herstellung von polyamiden

Legal Events

Date	Code	Title	Description
2009-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties