ATE412002T1 - Gruppen zum einfangen von nukleinsäuren - Google Patents

Gruppen zum einfangen von nukleinsäuren

Info

Publication number
ATE412002T1
ATE412002T1 AT96928976T AT96928976T ATE412002T1 AT E412002 T1 ATE412002 T1 AT E412002T1 AT 96928976 T AT96928976 T AT 96928976T AT 96928976 T AT96928976 T AT 96928976T AT E412002 T1 ATE412002 T1 AT E412002T1
Authority
AT
Austria
Prior art keywords
nucleic acid
captivity
groups
acid capture
capture moieties
Prior art date
Application number
AT96928976T
Other languages
English (en)
Inventor
Michael J Lane
Albert S Benight
Brian D Faldasz
Original Assignee
Luminex Molecular Diagnostics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luminex Molecular Diagnostics filed Critical Luminex Molecular Diagnostics
Application granted granted Critical
Publication of ATE412002T1 publication Critical patent/ATE412002T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT96928976T 1995-08-25 1996-08-23 Gruppen zum einfangen von nukleinsäuren ATE412002T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/519,197 US5770365A (en) 1995-08-25 1995-08-25 Nucleic acid capture moieties

Publications (1)

Publication Number Publication Date
ATE412002T1 true ATE412002T1 (de) 2008-11-15

Family

ID=24067290

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96928976T ATE412002T1 (de) 1995-08-25 1996-08-23 Gruppen zum einfangen von nukleinsäuren

Country Status (9)

Country Link
US (1) US5770365A (de)
EP (1) EP0861262B1 (de)
JP (1) JP2001517068A (de)
KR (1) KR19990044342A (de)
AT (1) ATE412002T1 (de)
AU (1) AU701632B2 (de)
CA (1) CA2227950A1 (de)
DE (1) DE69637726D1 (de)
WO (1) WO1997008183A1 (de)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6468742B2 (en) 1993-11-01 2002-10-22 Nanogen, Inc. Methods for determination of single nucleic acid polymorphisms using bioelectronic microchip
US7582421B2 (en) * 1993-11-01 2009-09-01 Nanogen, Inc. Methods for determination of single nucleic acid polymorphisms using a bioelectronic microchip
DE19527155C2 (de) * 1995-07-25 1998-12-10 Deutsches Krebsforsch Verfahren zur Sequenzierung durch Oligomerhybridisierung
DE69719057T2 (de) 1996-07-12 2003-12-04 Tm Technologies Inc., Woburn Verfahren zur signalverstärkung
US6485901B1 (en) 1997-10-27 2002-11-26 Boston Probes, Inc. Methods, kits and compositions pertaining to linear beacons
ATE478090T1 (de) 1997-10-27 2010-09-15 Boston Probes Inc SICH AUF ßPNA MOLECULAR BEACONSß BEZIEHENDE VERFAHREN, TESTSÄTZE UND ZUSAMMENSETZUNGEN
DE19808884A1 (de) * 1998-03-03 1999-09-16 November Ag Molekulare Medizin Vorrichtung und Verfahren zum Nachweis chemischer Substanzen
US6361942B1 (en) 1998-03-24 2002-03-26 Boston Probes, Inc. Method, kits and compositions pertaining to detection complexes
WO1999063077A2 (en) * 1998-06-04 1999-12-09 Tm Technologies, Inc. Compositions of nucleic acid which alter ligand-binding characteristics and related methods and products
GB0002310D0 (en) * 2000-02-01 2000-03-22 Solexa Ltd Polynucleotide sequencing
US20040106110A1 (en) * 1998-07-30 2004-06-03 Solexa, Ltd. Preparation of polynucleotide arrays
US6787308B2 (en) 1998-07-30 2004-09-07 Solexa Ltd. Arrayed biomolecules and their use in sequencing
US20030022207A1 (en) * 1998-10-16 2003-01-30 Solexa, Ltd. Arrayed polynucleotides and their use in genome analysis
US20100130368A1 (en) * 1998-07-30 2010-05-27 Shankar Balasubramanian Method and system for sequencing polynucleotides
JP2002522047A (ja) * 1998-08-04 2002-07-23 ティーエム テクノロジーズ， インク． 限界まで非弁別的なハイブリダイゼーションを調節する方法及び組成
US7244570B2 (en) 1998-08-04 2007-07-17 Luminex Molecular Diagnostics, Inc. Methods and compositions for modulating “marginally indiscriminant” hybridizations
WO2000026412A1 (en) * 1998-11-02 2000-05-11 Kenneth Loren Beattie Nucleic acid analysis using sequence-targeted tandem hybridization
US7790865B1 (en) 1999-02-02 2010-09-07 Qiagen North American Holdings, Inc Eluting reagents, methods and kits for isolating DNA
AU769929B2 (en) * 1999-04-12 2004-02-12 Nanogen, Inc. Methods for determination of single nucleic acid polymorphisms using a bioelectronic microchip
US8137906B2 (en) * 1999-06-07 2012-03-20 Sloning Biotechnology Gmbh Method for the synthesis of DNA fragments
US6964847B1 (en) 1999-07-14 2005-11-15 Packard Biosciences Company Derivative nucleic acids and uses thereof
JP2003527087A (ja) * 1999-08-13 2003-09-16 イェール・ユニバーシティ バイナリーコード化配列タグ
US6528319B1 (en) 1999-09-02 2003-03-04 Amersham Biosciences Corp Method for anchoring oligonucleotides to a substrate
US6924108B2 (en) 1999-12-21 2005-08-02 Ingeneus Corporation Nucleic acid binding enhancement by conjugation with nucleotides, nucleosides, bases and/or their analogues
AU2001267191A1 (en) * 2000-06-06 2001-12-17 Tm Bioscience Corporation Capture moieties for nucleic acids and uses thereof
JP2004510433A (ja) 2000-10-06 2004-04-08 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク Ｄｎａおよびｒｎａを解読するための大量並行方法
US9708358B2 (en) 2000-10-06 2017-07-18 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding DNA and RNA
US20040266021A9 (en) * 2001-01-26 2004-12-30 Andras Guttman Multicapillary fraction collection system and method
US20020187479A1 (en) * 2001-06-12 2002-12-12 Gayle Dace In vitro capture of nucleic acids via modified oligonucleotides and magnetic beads
US20030032028A1 (en) * 2001-06-12 2003-02-13 Gayle Dace In vitro capture of nucleic acids via modified oligonucleotides and magnetic beads
US20030082584A1 (en) * 2001-06-29 2003-05-01 Liang Shi Enzymatic ligation-based identification of transcript expression
US20030170695A1 (en) * 2001-06-29 2003-09-11 Liang Shi Enzymatic ligation-based identification of nucleotide sequences
ATE414767T1 (de) * 2001-11-22 2008-12-15 Sloning Biotechnology Gmbh Nukleinsäure-linker und deren verwendung in der gensynthese
US7282355B2 (en) * 2002-03-13 2007-10-16 Syngenta Participations Ag Nucleic acid detection method
US7601493B2 (en) * 2002-07-26 2009-10-13 Nanogen, Inc. Methods and apparatus for screening and detecting multiple genetic mutations
US7291459B2 (en) * 2002-12-10 2007-11-06 University Of Alabama At Huntsville Nucleic acid detector and method of detecting targets within a sample
US7851150B2 (en) * 2002-12-18 2010-12-14 Third Wave Technologies, Inc. Detection of small nucleic acids
US8206904B2 (en) 2002-12-18 2012-06-26 Third Wave Technologies, Inc. Detection of nucleic acids
US20050014134A1 (en) * 2003-03-06 2005-01-20 West Jason Andrew Appleton Viral identification by generation and detection of protein signatures
US20050074781A1 (en) * 2003-10-02 2005-04-07 Herbert von Schroeder Nucleic acid braided J-probes
US20050095602A1 (en) * 2003-11-04 2005-05-05 West Jason A. Microfluidic integrated microarrays for biological detection
GB0326073D0 (en) 2003-11-07 2003-12-10 Solexa Ltd Improvements in or relating to polynucleotide arrays
CA2545917C (en) 2003-11-14 2014-07-29 Duke University Methods of detecting charcot-marie tooth disease type 2a
US20050147976A1 (en) * 2003-12-29 2005-07-07 Xing Su Methods for determining nucleotide sequence information
GB0400584D0 (en) * 2004-01-12 2004-02-11 Solexa Ltd Nucleic acid chacterisation
ES2353302T3 (es) * 2004-01-23 2011-03-01 Sloning Biotechnology Gmbh Producción enzimática de novo de moléculas de ácido nucleico.
US7618778B2 (en) 2004-06-02 2009-11-17 Kaufman Joseph C Producing, cataloging and classifying sequence tags
WO2006007567A2 (en) * 2004-07-01 2006-01-19 Gen-Probe Incorporated Methods and compositions to detect nucleic acids in a biological sample
US7620402B2 (en) * 2004-07-09 2009-11-17 Itis Uk Limited System and method for geographically locating a mobile device
US7524672B2 (en) * 2004-09-22 2009-04-28 Sandia Corporation Microfluidic microarray systems and methods thereof
US7592139B2 (en) 2004-09-24 2009-09-22 Sandia National Laboratories High temperature flow-through device for rapid solubilization and analysis
US20070015176A1 (en) * 2005-02-18 2007-01-18 Applera Corporation Small nucleic acid detection probes and uses thereof
US9297036B2 (en) 2005-07-01 2016-03-29 Agilent Technologies, Inc Nucleic acid probes for analysis of small RNAs and other polynucleotides
US20070099193A1 (en) * 2005-11-01 2007-05-03 Hui Wang Probe/target stabilization with add-in oligo
US8551697B1 (en) 2005-12-09 2013-10-08 Applied Biosystems, Llc Electrochemical polynucleotide detection comprising ligation
US20070172841A1 (en) * 2006-01-25 2007-07-26 Hui Wang Probe/target stabilization with add-in oligo
US7754475B2 (en) * 2006-01-25 2010-07-13 Agilent Technologies, Inc. Nucleic acid probes and microarrays for analysis of polynucleotides
WO2008069973A2 (en) 2006-12-01 2008-06-12 The Trustees Of Columbia University In The City Of New York Four-color dna sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
US9938641B2 (en) * 2006-12-18 2018-04-10 Fluidigm Corporation Selection of aptamers based on geometry
WO2009051807A1 (en) 2007-10-19 2009-04-23 The Trustees Of Columbia University In The City Of New York Design and synthesis of cleavable fluorescent nucleotides as reversible terminators for dna sequencing by synthesis
DK2725107T3 (da) 2007-10-19 2019-01-02 Univ Columbia DNA-sekventering med ikke-fluorescerende nukleotidreversible terminatorer og ddNTP'er modificeret med spaltbart mærke og nukleinsyre omfattende inosin med reversible terminatorer
WO2009117327A2 (en) * 2008-03-15 2009-09-24 Hologic, Inc. Compositions and methods for analysis of nucleic acid molecules during amplification reactions
US9115352B2 (en) * 2008-03-31 2015-08-25 Sloning Biotechnology Gmbh Method for the preparation of a nucleic acid library
AU2009246363B2 (en) 2008-05-13 2013-10-24 Gen-Probe Incorporated Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences
JP2012509675A (ja) 2008-11-25 2012-04-26 ジェン−プロウブ インコーポレイテッド 低分子ｒｎａを検出するための組成物および方法、ならびにその使用
US8974651B2 (en) 2010-04-17 2015-03-10 C.C. Imex Illuminator for visualization of fluorophores
KR20130080007A (ko) 2010-05-11 2013-07-11 다우 아그로사이언시즈 엘엘씨 Ｓｐｎｋ 균주
EP2520653B1 (de) 2011-05-03 2017-03-29 Dow AgroSciences LLC Integration von Genen in das Chromosom von Saccharopolyspora spinosa
US20140004523A1 (en) * 2012-06-30 2014-01-02 Justine S. Chow Systems, methods, and a kit for determining the presence of fluids associated with a hydrocarbon reservoir in hydraulic fracturing
JP1628115S (de) 2012-10-24 2019-04-01
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
WO2014071322A1 (en) 2012-11-02 2014-05-08 Life Technologies Corporation Small RNA Capture, Detection and Quantification
WO2014144883A1 (en) 2013-03-15 2014-09-18 The Trustees Of Columbia University In The City Of New York Raman cluster tagged molecules for biological imaging
CN107866286A (zh) 2013-03-15 2018-04-03 金马克诊断股份有限公司 用于操纵可变形流体容器的系统、方法和设备
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
US9835587B2 (en) 2014-04-01 2017-12-05 C.C. Imex Electrophoresis running tank assembly
CN104195232A (zh) * 2014-07-24 2014-12-10 益善生物技术股份有限公司 抗微管类化疗药物疗效相关基因mRNA表达水平液相芯片检测试剂盒
CN104195229A (zh) * 2014-07-24 2014-12-10 益善生物技术股份有限公司 表皮生长因子受体抑制剂类药物疗效相关基因表达检测液相芯片试剂盒
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
EP3218108B1 (de) 2014-11-11 2020-09-02 Genmark Diagnostics Inc. Kartusche für fluidproben und ihre verwendung
US10563250B2 (en) 2015-03-13 2020-02-18 Life Technologies Corporation Methods, compositions and kits for small RNA capture, detection and quantification
EP3516401B1 (de) 2016-09-19 2025-07-30 Roche Diagnostics GmbH Instrument zur verarbeitung einer kassette zur durchführung von tests in einem geschlossenen probenvorbereitungs- und -reaktionssystem
WO2019011875A1 (en) 2017-07-11 2019-01-17 Qiagen Gmbh QUANTIFICATION OF ANTISENSE OLIGONUCLEOTIDES (ASOS)
EP4549590A3 (de) 2017-08-24 2025-08-06 Roche Diagnostics GmbH Elektrochemischer nachweis von bakteriellen und/oder pilzinfektionen
US20190062809A1 (en) 2017-08-24 2019-02-28 Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.) Electrochemical detection of bacterial and/or fungal infections
EP3963070A4 (de) 2019-04-30 2023-02-22 Encodia, Inc. Verfahren zur herstellung von analyten und zugehörige kits
WO2021252923A1 (en) 2020-06-12 2021-12-16 Genmark Diagnostics, Inc. Systems and methods for assessing bays on diagnostic devices

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
WO1991006679A1 (en) * 1989-10-24 1991-05-16 Stratagene An improved method for hybridizing nucleic acids using single-stranded nucleic acid binding protein
US5215899A (en) * 1989-11-09 1993-06-01 Miles Inc. Nucleic acid amplification employing ligatable hairpin probe and transcription
US5387510A (en) * 1991-10-02 1995-02-07 Eastman Kodak Company Detection of amplified nucleic acid using secondary capture oligonucleotides and test kit
US5503980A (en) * 1992-11-06 1996-04-02 Trustees Of Boston University Positional sequencing by hybridization
EP0708839A1 (de) * 1993-06-17 1996-05-01 ID Biomedical Corporation Verbesserte nukleinsäurereaktionen
US5556752A (en) * 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA

Also Published As

Publication number Publication date
DE69637726D1 (de) 2008-12-04
KR19990044342A (ko) 1999-06-25
EP0861262A1 (de) 1998-09-02
AU701632B2 (en) 1999-02-04
EP0861262A4 (de) 2000-07-12
US5770365A (en) 1998-06-23
JP2001517068A (ja) 2001-10-02
EP0861262B1 (de) 2008-10-22
AU6854596A (en) 1997-03-19
CA2227950A1 (en) 1997-03-06
WO1997008183A1 (en) 1997-03-06

Similar Documents

Publication Publication Date Title
ATE412002T1 (de) Gruppen zum einfangen von nukleinsäuren
RU94033149A (ru) Селективный ограничительный фрагмент амплификации: общий метод для днк "фингерпринтинга"
ATE346156T1 (de) Umkehrtransfektionsverfahren
DK0895806T3 (da) Fremgangsmåde til udførelse af endoterme reaktioner
DE69426956D1 (de) Nachweis von Mycobakterien durch Nukleinsäure-Multiplexamplifizierung
ATE199100T1 (de) Kettenabbrechende nukleinsäure-sequenziermethode mit 2'-desoxyuridin-5'-triphosphat
DE3875974D1 (de) Vorrichtung ohne netzanschluesse zum verpressen von richtungsmassen.
ATE346954T1 (de) Nachweis von mycobacterium tuberculosis durch vervielfältigung von nukleinsäuresequenzen
DE3788788D1 (de) Zange zum Spreizen von Wirbelsäulenkörpern.
DK0761822T3 (da) Fremgangsmåde til serieanalyse af genekspression
DE69020802D1 (de) Verfahren zum Ausheilen von Halbleitern.
ATE373105T1 (de) Verbindungen und methoden zum nachweis von biomolekülen
DE3576472D1 (de) Vorrichtung zum aufbauen von reifen.
DE69018625D1 (de) Verfahren zum aufkonzentrieren von chlorgas.
DK0889133T3 (da) Proces til frembringelse af mikrobiel transglutaminase
DE3882078D1 (de) Amperometrische methode zur titration von nadh (1,4-dihydronicotinamid-adenine-dinucleotide) in loesung.
DE3668560D1 (de) Verfahren zum reinigen, insbesondere entschwefelung von rauchgas.
FI883824L (fi) Etensampolymerisat.
TR199901115T2 (xx) Yeni metoprolol �retim i�lemi.
DE69202111D1 (de) Verfahren zum Lysieren von Mykobakterien.
NO992296D0 (no) FremgangsmÕte for disubstituerte pyridiner
DE69610785D1 (de) Verbesserter Wiederherstellungsprozess
EP0812234A4 (de) Membranverfahren zur behandlung von chlorhaltigen gasen
DE3769788D1 (de) Apparat zum stufenweisen durchfuehren von chemischen reaktionen.
NO882593D0 (no) Forbedret nykleinsyrehybridiseringsteknikk og kit til dette.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties