ATE421536T1 - Verfahren zur reinigung stark anionischer proteine - Google Patents

Verfahren zur reinigung stark anionischer proteine

Info

Publication number: ATE421536T1
Authority: AT; Austria
Prior art keywords: purifying; containing molecules; mixture; anionic proteins; strongly anionic
Prior art date: 2001-06-05

Application number

AT06010184T

Other languages

English (en)

Inventor

Jonathan L Coffmann

William B Foster

Shujun Sun

Original Assignee

Genetics Inst Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-05

Filing date

2002-06-05

Publication date

2009-02-15

2002-06-05 Application filed by Genetics Inst Llc filed Critical Genetics Inst Llc

2009-02-15 Application granted granted Critical

2009-02-15 Publication of ATE421536T1 publication Critical patent/ATE421536T1/de

Links

102000004169 proteins and genes Human genes 0.000 title abstract 3
108090000623 proteins and genes Proteins 0.000 title abstract 3
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
102100021935 C-C motif chemokine 26 Human genes 0.000 abstract 1
101000897493 Homo sapiens C-C motif chemokine 26 Proteins 0.000 abstract 1
239000013522 chelant Substances 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/828—Protein A

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Analytical Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT06010184T 2001-06-05 2002-06-05 Verfahren zur reinigung stark anionischer proteine ATE421536T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US29640201P	2001-06-05	2001-06-05

Publications (1)

Publication Number	Publication Date
ATE421536T1 true ATE421536T1 (de)	2009-02-15

Family

ID=23141860

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT06010184T ATE421536T1 (de)	2001-06-05	2002-06-05	Verfahren zur reinigung stark anionischer proteine
AT02749564T ATE333469T1 (de)	2001-06-05	2002-06-05	Verfahren zur reinigung hochanionischer proteine

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT02749564T ATE333469T1 (de)	2001-06-05	2002-06-05	Verfahren zur reinigung hochanionischer proteine

Country Status (11)

Country	Link
US (1)	US7223848B2 (de)
EP (2)	EP1404428B1 (de)
JP (1)	JP4288153B2 (de)
AT (2)	ATE421536T1 (de)
AU (1)	AU2008203302B2 (de)
CA (1)	CA2448788C (de)
DE (2)	DE60213248T2 (de)
DK (2)	DK1404428T3 (de)
ES (2)	ES2266535T3 (de)
NZ (1)	NZ530025A (de)
WO (1)	WO2002098531A1 (de)

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US8084032B2 (en)	2004-01-21	2011-12-27	Ajinomoto Co., Inc.	Purification method which prevents denaturation of an antibody
DE602006003108D1 (de) *	2005-03-03	2008-11-27	Ajinomoto Kk	Methode zur Verbesserung der Ausbeute bei der Proteinreinigung mittels Gelfiltrationschromatographie und Arginin
EP1963367A4 (de) *	2005-12-06	2009-05-13	Amgen Inc	Reinigungsschritte in mehrstufigen proteinreinigungsverfahren
WO2007081906A2 (en) *	2006-01-06	2007-07-19	Amgen Inc.	Purification by column-chromatography using eluants containing organic solvents
TW200821026A (en) *	2006-09-08	2008-05-16	Wyeth Corp	Arginine wash in protein purification using affinity chromatography
US8911964B2 (en)	2006-09-13	2014-12-16	Abbvie Inc.	Fed-batch method of making human anti-TNF-alpha antibody
TW201516149A (zh)	2006-09-13	2015-05-01	Abbvie Inc	細胞培養改良
DK2089429T3 (en) *	2006-10-19	2015-01-12	Janssen Biotech Inc	PROCEDURE FOR MANUFACTURING NON-AGGREGATED ANTIBODY-FC DOMAINS
CN104974251A (zh)	2008-10-20	2015-10-14	Abbvie公司	在抗体纯化过程中的病毒灭活
CA2932207A1 (en) *	2008-10-20	2010-12-09	Abbvie Inc.	Isolation and purification of antibodies using protein a affinity chromatography
US20120149875A1 (en) *	2009-01-12	2012-06-14	Ge Healthcare Bio-Sciences Ab	Affinity chromatography matrix
WO2011064910A1 (ja) *	2009-11-25	2011-06-03	パナソニック株式会社	免疫測定方法
BR112012014937B1 (pt)	2009-12-18	2021-01-19	Novartis Ag	método de produção de um anticorpo, fragmento de anticorpo ou proteína de fusão fc purificada usando uma matriz de cromatografia de afinidade
KR101953405B1 (ko)	2011-06-01	2019-02-28	노파르티스 아게	친화성 크로마토그래피를 위한 세척 용액 및 방법
WO2021147857A1 (en) *	2020-01-20	2021-07-29	Wuxi Biologics (Shanghai) Co., Ltd	A novel wash buffer solution for affinity chromatography

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US5115101A (en) *	1988-06-08	1992-05-19	Miles Inc.	Removal of protein A from antibody preparations
US4983722A (en) *	1988-06-08	1991-01-08	Miles Inc.	Removal of protein A from antibody preparations
US5464778A (en)	1989-03-08	1995-11-07	Board Of Regents Of The University Of Oklahoma	Glycoprotein ligand for P-selectin and methods of use thereof
GB9022547D0 (en) *	1990-10-17	1990-11-28	Wellcome Found	Purified immunoglobulin
US5726293A (en) *	1992-10-02	1998-03-10	The General Hospital Corporation	Affinity purification methods involving imidazole elution
US5843707A (en)	1992-10-23	1998-12-01	Genetics Institute, Inc.	Nucleic acid encoding a novel P-selectin ligand protein
US6277975B1 (en)	1992-10-23	2001-08-21	Genetics Institute, Inc.	Fusions of P-selectin ligand protein and polynucleotides encoding same
US5429746A (en)	1994-02-22	1995-07-04	Smith Kline Beecham Corporation	Antibody purification
EP1104809A1 (de)	1994-04-09	2001-06-06	F. Hoffmann-La Roche Ag	Verfahren zur Herstellung von Alpha-Interferon
US6008328A (en)	1994-10-13	1999-12-28	Amgen Inc.	Method for purifying keratinocyte growth factors
SE503424C2 (sv)	1994-11-14	1996-06-10	Pharmacia Ab	Process för rening av rekombinant koagulationsfaktor VIII
FR2737730B1 (fr)	1995-08-10	1997-09-05	Pasteur Merieux Serums Vacc	Procede de purification de virus par chromatographie
FR2738009B1 (fr)	1995-08-24	1997-10-31	Centre Nat Rech Scient	Procede d'obtention de polysaccharides sulfates
AU729459B2 (en)	1996-11-15	2001-02-01	Genentech Inc.	Purification of neurotrophins
ES2293661T3 (es) *	1996-11-27	2008-03-16	Genentech, Inc.	Purificacion por afinidad de polipeptido en una matriz de proteinas a.
DE69930653T2 (de)	1998-09-24	2007-01-25	Pharming Intellectual Property Bv	Reinigung von fibrinogen aus milch durch den einsatz von kationenaustauschchromatographie
CN1342085A (zh) *	1998-10-30	2002-03-27	遗传研究所有限公司	通过p－选择素配体(psgl)拮抗剂抑制细胞素t细胞的分化
JP2003517580A (ja)	1999-01-21	2003-05-27	メタモーフイクス・インコーポレーテツド	増殖分化因子インヒビター及びそれらの用途
EP1681299B1 (de) *	2000-03-27	2009-11-11	Genetics Institute, LLC	Verfahren zur Reinigung stark anionischer Proteine

2002
- 2002-06-05 EP EP02749564A patent/EP1404428B1/de not_active Expired - Lifetime
- 2002-06-05 ES ES02749564T patent/ES2266535T3/es not_active Expired - Lifetime
- 2002-06-05 DE DE60213248T patent/DE60213248T2/de not_active Expired - Lifetime
- 2002-06-05 DE DE60231016T patent/DE60231016D1/de not_active Expired - Lifetime
- 2002-06-05 AT AT06010184T patent/ATE421536T1/de not_active IP Right Cessation
- 2002-06-05 DK DK02749564T patent/DK1404428T3/da active
- 2002-06-05 ES ES06010184T patent/ES2321539T3/es not_active Expired - Lifetime
- 2002-06-05 DK DK06010184T patent/DK1714982T3/da active
- 2002-06-05 WO PCT/US2002/018081 patent/WO2002098531A1/en not_active Ceased
- 2002-06-05 JP JP2003501567A patent/JP4288153B2/ja not_active Expired - Fee Related
- 2002-06-05 CA CA2448788A patent/CA2448788C/en not_active Expired - Fee Related
- 2002-06-05 NZ NZ530025A patent/NZ530025A/en unknown
- 2002-06-05 AT AT02749564T patent/ATE333469T1/de not_active IP Right Cessation
- 2002-06-05 EP EP06010184A patent/EP1714982B1/de not_active Expired - Lifetime
- 2002-06-05 US US10/163,853 patent/US7223848B2/en not_active Expired - Fee Related
2008
- 2008-07-24 AU AU2008203302A patent/AU2008203302B2/en not_active Ceased

Also Published As

Publication number	Publication date
US7223848B2 (en)	2007-05-29
EP1404428B1 (de)	2006-07-19
ATE333469T1 (de)	2006-08-15
NZ530025A (en)	2005-06-24
ES2321539T3 (es)	2009-06-08
EP1404428A1 (de)	2004-04-07
CA2448788A1 (en)	2002-12-12
AU2008203302B2 (en)	2011-10-27
DE60213248D1 (de)	2006-08-31
EP1714982A3 (de)	2006-12-20
JP4288153B2 (ja)	2009-07-01
ES2266535T3 (es)	2007-03-01
DE60231016D1 (de)	2009-03-12
EP1714982A2 (de)	2006-10-25
WO2002098531A1 (en)	2002-12-12
AU2008203302A1 (en)	2008-08-14
EP1714982B1 (de)	2009-01-21
US20030050450A1 (en)	2003-03-13
DK1404428T3 (da)	2006-10-30
EP1404428A4 (de)	2004-12-08
DE60213248T2 (de)	2006-11-30
CA2448788C (en)	2010-08-24
JP2004537042A (ja)	2004-12-09
DK1714982T3 (da)	2009-05-04

Legal Events

Date	Code	Title	Description
2009-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60231016D1 (de)	2009-03-12	Verfahren zur Reinigung stark anionischer Proteine
DE60030323D1 (de)	2006-10-05	Verfahren und verbindungen zur verlängerung der halbwertzeiten bei der ausscheidung von biowirksamen verbindungen
ATE342353T1 (de)	2006-11-15	Abtrennung von plasmin(ogen) aus proteinlösungen
AU2658397A (en)	1997-10-10	Purification of tissue plasminogen activator (tpa)
ATE278785T1 (de)	2004-10-15	Neues verfahren zur gewinnung und reinigung von fusionsproteinen
ATE200293T1 (de)	2001-04-15	Verfahren zur chromatographischen reinigung und trennung von nucleinsäuregemischen
WO2002057290A8 (en)	2003-11-13	Novel fibronectin epitopes and proteinaceous molecules capable of binding said epitopes
ATE449104T1 (de)	2009-12-15	Verfahren zur reinigung von fibrinogen
DE60104833D1 (de)	2004-09-16	Verfahren zur abtrennung von einer basischen aminosäure aus fermentationsbrühen
DE50012831D1 (de)	2006-06-29	Verfahren zur verbindung von molekularen substanzen
DE69435020D1 (en)	2007-10-18	Protein-tyrosin-phosphatase ptp-s31
ATE417056T1 (de)	2008-12-15	Verfahren zur proteinreinigung
Vosbeck et al.	1975	The proteolytic enzymes of the K-1 strain of Streptomyces griseus obtained from a commercial preparation (Pronase). Specificity and immobilization of aminopeptidase.
DK1105508T3 (da)	2003-01-06	Fremgangsmåde til oprensning af biomolekyle- eller proteinkomplekser
DE60140493D1 (de)	2009-12-24	Verfahren zur Reinigung stark anionischer Proteine
ATE242782T1 (de)	2003-06-15	Verfahren zur herstellung von peptiden aus biologischen flüssigkeiten und nach diesem verfahren herstellbare peptide
ATE215964T1 (de)	2002-04-15	Phrothrombin und thrombin bindende peptide.
ATE278699T1 (de)	2004-10-15	Verfahren zur aufreinigung von nukleinsäuren sowie anionenaustauscher zur durchführung dieses verfahrens
DE60039533D1 (de)	2008-08-28	Verbessertes verfahren zur herstellung von 2s,3s-n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamid hydrochlorid und anderen derivaten von 2-hydroxy-1,3-diamin
PL340728A1 (en)	2001-02-26	Histamine and serotonin bonding molecules
WO2004007536A3 (en)	2004-05-06	Interactions of the epstein-barr virus protein ebna1, and uses thereof
ATE220419T1 (de)	2002-07-15	Verfahren zur herstellung von cis-3-hydroxy-l- prolin
ATE380197T1 (de)	2007-12-15	Verfahren zur reinigung von epi-hne proteinen
MX9606617A (es)	1998-01-31	Resinas hidrofobicas con grupos ionizables para cromatografia.