ATE422903T1 - Verfahren zur herstellung von einer 2-18f-fluor-2-deoxy-d-glucose (18fdg)-lösung - Google Patents

Verfahren zur herstellung von einer 2-18f-fluor-2-deoxy-d-glucose (18fdg)-lösung

Info

Publication number
ATE422903T1
ATE422903T1 AT03721834T AT03721834T ATE422903T1 AT E422903 T1 ATE422903 T1 AT E422903T1 AT 03721834 T AT03721834 T AT 03721834T AT 03721834 T AT03721834 T AT 03721834T AT E422903 T1 ATE422903 T1 AT E422903T1
Authority
AT
Austria
Prior art keywords
deoxy
glucose
solution
fdg
fluor
Prior art date
Application number
AT03721834T
Other languages
English (en)
Inventor
Petrus Kruijer
Castro Hector Knight
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Application granted granted Critical
Publication of ATE422903T1 publication Critical patent/ATE422903T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121—Solutions, i.e. homogeneous liquid formulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C07B63/04—Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03721834T 2002-04-24 2003-04-23 Verfahren zur herstellung von einer 2-18f-fluor-2-deoxy-d-glucose (18fdg)-lösung ATE422903T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02076638A EP1356827A1 (de) 2002-04-24 2002-04-24 Verfahren zur Herstellung von einer 2-18F-Fluor-2-Deoxy-D-Glucose (18F-FDG)-Lösung

Publications (1)

Publication Number Publication Date
ATE422903T1 true ATE422903T1 (de) 2009-03-15

Family

ID=28685968

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03721834T ATE422903T1 (de) 2002-04-24 2003-04-23 Verfahren zur herstellung von einer 2-18f-fluor-2-deoxy-d-glucose (18fdg)-lösung

Country Status (13)

Country Link
US (1) US8182788B2 (de)
EP (2) EP1356827A1 (de)
JP (2) JP5132869B2 (de)
KR (1) KR20050005456A (de)
CN (1) CN1323724C (de)
AT (1) ATE422903T1 (de)
AU (1) AU2003225124B2 (de)
CA (1) CA2483181C (de)
DE (1) DE60326220D1 (de)
IL (2) IL164805A0 (de)
NO (1) NO329160B1 (de)
PL (1) PL371682A1 (de)
WO (1) WO2003090789A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0422004D0 (en) 2004-10-05 2004-11-03 Amersham Plc Method of deprotection
KR20080022108A (ko) * 2005-06-14 2008-03-10 니혼 메디피직스 가부시키가이샤 방사성 화상 진단제
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
US8277777B2 (en) * 2006-06-21 2012-10-02 Nihon Medi-Physics Co., Ltd. Compound having affinity for amyloid
WO2007148083A2 (en) * 2006-06-21 2007-12-27 Ge Healthcare As Stabilisation of radiopharmaceutical precursors
EP2080526A4 (de) * 2006-11-09 2012-11-07 Nihon Mediphysics Co Ltd Radioaktives diagnostisches abbildungsagens
KR101497406B1 (ko) 2006-12-21 2015-03-02 니혼 메디피직스 가부시키가이샤 방사성 화상 진단제
JP5258583B2 (ja) * 2007-02-13 2013-08-07 日本メジフィジックス株式会社 放射性画像診断剤の製造方法
AU2008314870A1 (en) * 2007-10-24 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
CN102702195A (zh) * 2007-10-30 2012-10-03 日本医事物理股份有限公司 对淀粉样蛋白具有亲和性的新化合物的应用及制备方法
AU2008319985A1 (en) * 2007-10-30 2009-05-07 Nihon Medi-Physics Co., Ltd. Use of novel compound having affinity for amyloid, and process for production of the same
WO2009059977A1 (en) * 2007-11-07 2009-05-14 Ge Healthcare Bv Stabilization of radiopharmaceuticals
LT2419096T (lt) 2009-04-15 2020-04-10 Lantheus Medical Imaging, Inc. Radiofarmacinės kompozicijos stabilizavimas naudojant askorbo rūgštį
ES2785990T3 (es) 2010-08-13 2020-10-08 Siemens Medical Solutions Usa Inc Formulación, aparato y método para estabilizar productos radiofarmacéuticos
AU2011351550B2 (en) 2010-12-29 2017-02-02 Ge Healthcare Limited Eluent solution
EP2793954B1 (de) * 2011-12-21 2020-10-21 GE Healthcare Limited 18f-fluciclovinzusammensetzungen in citratpuffern
US20130004414A1 (en) * 2011-06-30 2013-01-03 General Electric Company Devices and methods for reducing radiolysis of radioisotopes
US20130005958A1 (en) * 2011-06-30 2013-01-03 General Electric Company Devices and methods for reducing radiolysis of radioisotopes
GB201411569D0 (en) 2014-06-30 2014-08-13 Ge Healthcare Ltd Novel formulation and method of synthesis
US11534494B2 (en) 2011-12-21 2022-12-27 Ge Healthcare Limited Formulation and method of synthesis
GB201202420D0 (en) * 2012-02-13 2012-03-28 Ge Healthcare Ltd Radiotracer compositions
US10695450B2 (en) 2016-07-26 2020-06-30 Laboratoires Cyclopharma Synthesis of a radioactive agent composition
FR3054445B1 (fr) * 2016-07-26 2019-07-05 Laboratoires Cyclopharma Synthese d'une composition d'agent radioactif
GB202005282D0 (en) 2020-04-09 2020-05-27 Blue Earth Diagnostics Ltd Pharmaceutical Formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707353A (en) * 1982-12-08 1987-11-17 Mallinckrodt, Inc. Radiographic imaging agents
SE9002117L (sv) * 1990-06-14 1991-08-26 Nils Elander Mikrovaagsanordning foer behandling av precessvaetskor
JP3370666B2 (ja) 1990-07-06 2003-01-27 マリンクロッド・インコーポレイテッド 放射性レニウム錯体溶液の調製法
JPH0797340A (ja) * 1993-06-03 1995-04-11 Terumo Corp Ｍｒｉ造影剤組成物
BE1010280A3 (fr) 1996-05-02 1998-05-05 Coincidence S A Procede et dispositif de synthese de 2-[18f] fluoro-2-deoxy-d-glucose.
EP1293214A3 (de) * 1996-10-07 2003-03-26 Bristol-Myers Squibb Pharma Company LTB4 Antagonisten und Radiopharmazeutika für Bilderzeugung der Infektion und Entzündung

Also Published As

Publication number Publication date
JP2006500319A (ja) 2006-01-05
IL164805A (en) 2009-06-15
EP1496946B1 (de) 2009-02-18
US20050175536A1 (en) 2005-08-11
CN1323724C (zh) 2007-07-04
AU2003225124B2 (en) 2007-06-14
CA2483181A1 (en) 2003-11-06
JP2010248244A (ja) 2010-11-04
NO329160B1 (no) 2010-08-30
CA2483181C (en) 2011-06-28
NO20045070L (no) 2004-11-22
IL164805A0 (en) 2005-12-18
PL371682A1 (en) 2005-06-27
WO2003090789A1 (en) 2003-11-06
EP1496946A1 (de) 2005-01-19
CN1646175A (zh) 2005-07-27
DE60326220D1 (de) 2009-04-02
AU2003225124A1 (en) 2003-11-10
US8182788B2 (en) 2012-05-22
KR20050005456A (ko) 2005-01-13
JP5132869B2 (ja) 2013-01-30
EP1356827A1 (de) 2003-10-29

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