ATE543817T1 - Verfahren zur herstellung einer imidverbindung - Google Patents
Verfahren zur herstellung einer imidverbindungInfo
- Publication number
- ATE543817T1 ATE543817T1 AT04748182T AT04748182T ATE543817T1 AT E543817 T1 ATE543817 T1 AT E543817T1 AT 04748182 T AT04748182 T AT 04748182T AT 04748182 T AT04748182 T AT 04748182T AT E543817 T1 ATE543817 T1 AT E543817T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- imide compound
- formula
- compound hydrochloride
- imide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003281860 | 2003-07-29 | ||
| PCT/JP2004/011035 WO2005009999A1 (ja) | 2003-07-29 | 2004-07-27 | イミド化合物の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE543817T1 true ATE543817T1 (de) | 2012-02-15 |
Family
ID=34100970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04748182T ATE543817T1 (de) | 2003-07-29 | 2004-07-27 | Verfahren zur herstellung einer imidverbindung |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7605260B2 (de) |
| EP (1) | EP1652848B1 (de) |
| JP (1) | JP4610485B2 (de) |
| KR (1) | KR101085806B1 (de) |
| CN (1) | CN100422178C (de) |
| AT (1) | ATE543817T1 (de) |
| AU (1) | AU2004259305B2 (de) |
| BR (1) | BRPI0413081B8 (de) |
| CA (1) | CA2538265C (de) |
| DK (1) | DK1652848T3 (de) |
| ES (1) | ES2378990T3 (de) |
| WO (1) | WO2005009999A1 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8283352B2 (en) | 2005-06-13 | 2012-10-09 | Dainippon Sumitomo Pharma Co., Ltd. | Solubilization preparation |
| CA2682494C (en) | 2007-04-04 | 2011-10-11 | Merck & Co., Inc. | Hexahydro-1h-4,7-methanoisoindole-1,3-dione compounds for treating psychiatric disorders |
| WO2011093522A1 (en) * | 2010-01-28 | 2011-08-04 | Dainippon Sumitomo Pharma Co., Ltd. | A cycloalkane derivative |
| ES2594709T3 (es) | 2010-04-26 | 2016-12-22 | Sumitomo Dainippon Pharma Co., Ltd. | Un proceso de preparación de una sal de amonio cuaternario |
| EP2629775A4 (de) * | 2010-10-18 | 2014-06-11 | Dainippon Sumitomo Pharma Co | Injizierbare formulierung mit verzögerter freisetzung |
| WO2012107890A2 (en) | 2011-02-10 | 2012-08-16 | Ranbaxy Laboratories Limited | Crystalline forms of lurasidone hydrochloride |
| WO2012123858A1 (en) | 2011-03-14 | 2012-09-20 | Ranbaxy Laboratories Limited | Amorphous lurasidone hydrochloride |
| US8981095B2 (en) | 2011-07-28 | 2015-03-17 | Mapi Pharma Ltd. | Intermediate compounds and process for the preparation of lurasidone and salts thereof |
| CZ304027B6 (cs) * | 2011-08-18 | 2013-08-28 | Farmak, A. S. | Zpusob prípravy polymorfu (1R,2S,3R,4S)-N-[(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl]-1-cyklohexylmethyl]-2,3-bicyklo[2.2.1]heptandikarboximidu hydrochloridu |
| CN102952064A (zh) * | 2011-08-19 | 2013-03-06 | 天津药物研究院 | 一种医药中间体顺式-外-二环[2.2.1]庚烷-2.3-二甲酰亚胺的制备方法 |
| WO2013030722A1 (en) | 2011-08-26 | 2013-03-07 | Ranbaxy Laboratories Limited | Crystalline lurasidone hydrochloride |
| CN103130794B (zh) * | 2011-12-02 | 2016-06-22 | 苏州二叶制药有限公司 | 卢拉西酮盐酸盐的晶体a的制备方法 |
| CN103130795A (zh) * | 2011-12-02 | 2013-06-05 | 苏州二叶制药有限公司 | 卢拉西酮盐酸盐的晶体a及其用途 |
| US9409899B2 (en) | 2012-02-13 | 2016-08-09 | Cadila Healthcare Limited | Process for preparing benzisothiazol-3-yl-piperazin-1-yl-methyl-cyclo hexylmethanisoindol-1,3-dione and its intermediates |
| CN103360383B (zh) * | 2012-04-11 | 2016-07-06 | 上海医药工业研究院 | 鲁拉西酮盐酸盐的晶型b及其制备方法 |
| CN102746289B (zh) * | 2012-04-28 | 2016-06-08 | 上海医药工业研究院 | 一种盐酸卢拉西酮的制备方法 |
| WO2013190455A2 (en) * | 2012-06-18 | 2013-12-27 | Shasun Pharmaceuticals Limited | Process for the preparation of lurasidone hydrochloride |
| CN102863437A (zh) * | 2012-09-04 | 2013-01-09 | 济南百诺医药科技开发有限公司 | 一种鲁拉西酮的制备方法 |
| WO2014064714A2 (en) * | 2012-10-22 | 2014-05-01 | Glenmark Pharmaceuticals Limited; Glenmark Generics Limited | Process for preparation of lurasidone hydrochloride |
| CN102911170A (zh) * | 2012-11-15 | 2013-02-06 | 苏州第壹制药有限公司 | 酰亚胺化合物盐酸盐的制备方法 |
| CN105524057A (zh) * | 2013-03-06 | 2016-04-27 | 江苏恩华药业股份有限公司 | 盐酸鲁拉西酮的新晶型及其制备方法 |
| CN103539794A (zh) * | 2013-10-17 | 2014-01-29 | 常州大学 | 一种盐酸鲁拉西酮的成盐方法 |
| CZ306203B6 (cs) * | 2013-12-06 | 2016-09-29 | Zentiva, K. S | Způsob syntézy lurasidonu |
| JP6594351B2 (ja) | 2014-06-16 | 2019-10-23 | ジョンソン、マッセイ、パブリック、リミテッド、カンパニー | 新規中間体を含むアルキル化アリールピペラジン及びアルキル化アリールピペリジン化合物の製造方法 |
| US10426770B2 (en) | 2014-10-14 | 2019-10-01 | Jubilant Generics Limited | Process for the preparation of Lurasidone hydrochloride |
| CN111989102A (zh) | 2018-02-28 | 2020-11-24 | 大日本住友制药株式会社 | 水性混悬液型药物制剂 |
| JPWO2019167978A1 (ja) | 2018-02-28 | 2021-02-04 | 大日本住友製薬株式会社 | 溶出が制御された水性懸濁型医薬製剤 |
| CN113024535B (zh) | 2019-12-24 | 2024-08-02 | 上海科胜药物研发有限公司 | 一种鲁拉西酮盐酸盐的制备方法 |
| CN115950695B (zh) * | 2021-10-09 | 2023-07-28 | 北京阳光诺和药物研究股份有限公司 | 一种制备鲁拉西酮基毒杂质的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS517440A (de) * | 1974-07-08 | 1976-01-21 | Japan Storage Battery Co Ltd | |
| JPS57197265A (en) | 1981-05-29 | 1982-12-03 | Eisai Co Ltd | Carboxylic acid imide derivative, its preparation and medicament containing the same |
| AU615966B2 (en) | 1987-12-04 | 1991-10-17 | Takeda Chemical Industries Ltd. | Crystals of cephem hydrochloride |
| JP2800953B2 (ja) | 1990-07-06 | 1998-09-21 | 住友製薬株式会社 | 新規なイミド誘導体 |
| US5663381A (en) * | 1995-04-21 | 1997-09-02 | Hexal Pharmaceuticals, Inc. | Process for preparing form 1 ranitidine hydrochloride |
| DK1254092T3 (da) | 2000-02-11 | 2004-03-15 | Degussa | Resolvering af DL-racemiske blandinger |
| AU2001246861A1 (en) * | 2000-04-10 | 2001-10-23 | Sumitomo Pharmaceuticals Co. Ltd. | Sustained release preparations |
| CA2431041A1 (en) * | 2001-01-02 | 2002-07-11 | Pharmacia & Upjohn Company | New drug combinations of norepinehrine reuptake inhibitors and neuroleptic agents |
-
2004
- 2004-07-27 KR KR1020067001255A patent/KR101085806B1/ko not_active Expired - Lifetime
- 2004-07-27 US US10/565,105 patent/US7605260B2/en not_active Expired - Lifetime
- 2004-07-27 ES ES04748182T patent/ES2378990T3/es not_active Expired - Lifetime
- 2004-07-27 CN CNB2004800221687A patent/CN100422178C/zh not_active Expired - Lifetime
- 2004-07-27 WO PCT/JP2004/011035 patent/WO2005009999A1/ja not_active Ceased
- 2004-07-27 AT AT04748182T patent/ATE543817T1/de active
- 2004-07-27 BR BRPI0413081A patent/BRPI0413081B8/pt not_active IP Right Cessation
- 2004-07-27 CA CA2538265A patent/CA2538265C/en not_active Expired - Lifetime
- 2004-07-27 DK DK04748182.5T patent/DK1652848T3/da active
- 2004-07-27 US US14/137,464 patent/USRE45573E1/en not_active Expired - Lifetime
- 2004-07-27 JP JP2005512110A patent/JP4610485B2/ja not_active Expired - Lifetime
- 2004-07-27 AU AU2004259305A patent/AU2004259305B2/en not_active Expired
- 2004-07-27 EP EP04748182A patent/EP1652848B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2005009999A1 (ja) | 2006-09-07 |
| BRPI0413081B1 (pt) | 2018-03-20 |
| DK1652848T3 (da) | 2012-02-27 |
| EP1652848A1 (de) | 2006-05-03 |
| CN1832946A (zh) | 2006-09-13 |
| KR101085806B1 (ko) | 2011-11-22 |
| CA2538265A1 (en) | 2005-02-03 |
| AU2004259305B2 (en) | 2009-06-04 |
| JP4610485B2 (ja) | 2011-01-12 |
| BRPI0413081A (pt) | 2006-10-03 |
| CN100422178C (zh) | 2008-10-01 |
| CA2538265C (en) | 2012-10-02 |
| EP1652848B1 (de) | 2012-02-01 |
| US7605260B2 (en) | 2009-10-20 |
| WO2005009999A1 (ja) | 2005-02-03 |
| ES2378990T3 (es) | 2012-04-19 |
| EP1652848A4 (de) | 2009-04-15 |
| USRE45573E1 (en) | 2015-06-23 |
| AU2004259305A1 (en) | 2005-02-03 |
| US20060194970A1 (en) | 2006-08-31 |
| KR20060052840A (ko) | 2006-05-19 |
| BRPI0413081B8 (pt) | 2021-05-25 |
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