ATE424187T1 - Bioerodierbare folie zur abgabe eines ophthalmischen arzneimittels - Google Patents

Bioerodierbare folie zur abgabe eines ophthalmischen arzneimittels

Info

Publication number
ATE424187T1
ATE424187T1 AT03764333T AT03764333T ATE424187T1 AT E424187 T1 ATE424187 T1 AT E424187T1 AT 03764333 T AT03764333 T AT 03764333T AT 03764333 T AT03764333 T AT 03764333T AT E424187 T1 ATE424187 T1 AT E424187T1
Authority
AT
Austria
Prior art keywords
delivering
medicinal product
film
ophthalmic medicinal
bioerodible
Prior art date
Application number
AT03764333T
Other languages
English (en)
Inventor
Bhagwati Kabra
Janet Howie
Youqin Tian
David Marsh
Gustav Graff
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of ATE424187T1 publication Critical patent/ATE424187T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03764333T 2002-07-15 2003-06-30 Bioerodierbare folie zur abgabe eines ophthalmischen arzneimittels ATE424187T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39584002P 2002-07-15 2002-07-15
US43272102P 2002-12-12 2002-12-12

Publications (1)

Publication Number Publication Date
ATE424187T1 true ATE424187T1 (de) 2009-03-15

Family

ID=30118549

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03764333T ATE424187T1 (de) 2002-07-15 2003-06-30 Bioerodierbare folie zur abgabe eines ophthalmischen arzneimittels

Country Status (17)

Country Link
US (1) US8084054B2 (de)
EP (1) EP1521572B1 (de)
JP (1) JP4454019B2 (de)
KR (1) KR101003514B1 (de)
CN (1) CN100500221C (de)
AT (1) ATE424187T1 (de)
AU (1) AU2003247671B2 (de)
CA (1) CA2491312C (de)
CY (1) CY1109606T1 (de)
DE (1) DE60326455D1 (de)
DK (1) DK1521572T3 (de)
ES (1) ES2321083T3 (de)
MX (1) MXPA05000631A (de)
PL (1) PL206379B1 (de)
PT (1) PT1521572E (de)
SI (1) SI1521572T1 (de)
WO (1) WO2004006889A1 (de)

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US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
CA2757037C (en) 2009-01-29 2019-08-06 Forsight Vision4, Inc. Posterior segment drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
CA2807065A1 (en) * 2010-07-29 2012-02-02 Santen Pharmaceutical Co., Ltd. Drug support body, and method for producing same
EP2600876B1 (de) 2010-08-05 2015-04-29 Forsight Vision4, Inc. Verfahren und vorrichtung zur verabreichung kombinierter arzneimittel
WO2012019136A2 (en) 2010-08-05 2012-02-09 Forsight Vision 4, Inc. Injector apparatus and method for drug delivery
PT2600812T (pt) 2010-08-05 2021-11-09 Forsight Vision4 Inc Aparelho para tratar um olho
WO2012068549A2 (en) 2010-11-19 2012-05-24 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
JPWO2012153870A1 (ja) * 2011-05-11 2014-07-31 帝人株式会社 緑内障治療材
US20120302954A1 (en) * 2011-05-25 2012-11-29 Zhao Jonathon Z Expandable devices coated with a paclitaxel composition
WO2013003620A2 (en) 2011-06-28 2013-01-03 Forsight Vision4, Inc. Diagnostic methods and apparatus
ES2864203T3 (es) 2011-09-16 2021-10-13 Forsight Vision4 Inc Aparato de intercambio de fluido
WO2013116061A1 (en) 2012-02-03 2013-08-08 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
AU2012385956B2 (en) 2012-07-23 2017-03-30 Crayola, Llc Dissolvable films and methods of using the same
EP2968113B8 (de) 2013-03-14 2020-10-28 Forsight Vision4, Inc. Systeme zur verzögerten intraokularen abgabe schwerlöslicher verbindungen aus einem implantat mit einem portabgabesystem
CN105246438B (zh) 2013-03-28 2018-01-26 弗赛特影像4股份有限公司 用于输送治疗物质的眼科植入物
MX384889B (es) 2014-07-15 2025-03-14 Forsight Vision4 Inc Dispositivo y metodo de entrega de implante ocular.
KR20170040798A (ko) 2014-08-08 2017-04-13 포사이트 비젼4, 인크. 수용체 티로신 키나제 억제제의 안정한 가용성 제제 및 그의 제조 방법
EP3217924B1 (de) 2014-11-10 2025-07-16 ForSight Vision4, Inc. Expandierbare wirkstofffreisetzungsvorrichtungen
KR20180084104A (ko) 2015-11-20 2018-07-24 포사이트 비젼4, 인크. 연장 방출 약물 전달 장치를 위한 다공성 구조물
US11617680B2 (en) 2016-04-05 2023-04-04 Forsight Vision4, Inc. Implantable ocular drug delivery devices
CN115607358A (zh) 2017-11-21 2023-01-17 弗赛特影像4股份有限公司 用于可扩展端口递送系统的流体交换装置及使用方法
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EP4590283A1 (de) * 2022-09-23 2025-07-30 Madd Ophthalmics Ltd. Mukoadhäsive wirkstofffreisetzungssysteme und verfahren zur verwendung

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Also Published As

Publication number Publication date
EP1521572B1 (de) 2009-03-04
CA2491312C (en) 2011-05-31
AU2003247671B2 (en) 2008-02-14
WO2004006889A1 (en) 2004-01-22
KR101003514B1 (ko) 2010-12-30
EP1521572A1 (de) 2005-04-13
DK1521572T3 (da) 2009-05-04
KR20050025961A (ko) 2005-03-14
PT1521572E (pt) 2009-04-21
SI1521572T1 (sl) 2009-06-30
DE60326455D1 (de) 2009-04-16
JP4454019B2 (ja) 2010-04-21
CA2491312A1 (en) 2004-01-22
CN100500221C (zh) 2009-06-17
ES2321083T3 (es) 2009-06-02
PL206379B1 (pl) 2010-08-31
US20040126408A1 (en) 2004-07-01
CN1668278A (zh) 2005-09-14
MXPA05000631A (es) 2005-03-31
AU2003247671A1 (en) 2004-02-02
US8084054B2 (en) 2011-12-27
JP2005533106A (ja) 2005-11-04
PL374764A1 (en) 2005-10-31
CY1109606T1 (el) 2014-08-13

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