ATE428702T1 - Verfahren zur herstellung von aminosäurederivaten - Google Patents
Verfahren zur herstellung von aminosäurederivatenInfo
- Publication number
- ATE428702T1 ATE428702T1 AT06803891T AT06803891T ATE428702T1 AT E428702 T1 ATE428702 T1 AT E428702T1 AT 06803891 T AT06803891 T AT 06803891T AT 06803891 T AT06803891 T AT 06803891T AT E428702 T1 ATE428702 T1 AT E428702T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- acid derivatives
- invention comprises
- avoiding
- producing amino
- Prior art date
Links
- 150000003862 amino acid derivatives Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- SDGKUVSVPIIUCF-KNVOCYPGSA-N (2r,6s)-2,6-dimethylpiperidine Chemical compound C[C@H]1CCC[C@@H](C)N1 SDGKUVSVPIIUCF-KNVOCYPGSA-N 0.000 abstract 1
- ZFHUHPNDGVGXMS-UHFFFAOYSA-N 4-(hydroxymethyl)benzaldehyde Chemical compound OCC1=CC=C(C=O)C=C1 ZFHUHPNDGVGXMS-UHFFFAOYSA-N 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 238000009876 asymmetric hydrogenation reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 238000007086 side reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71899505P | 2005-09-21 | 2005-09-21 | |
| PCT/US2006/036607 WO2007038116A1 (en) | 2005-09-21 | 2006-09-20 | Process to prepare amino acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE428702T1 true ATE428702T1 (de) | 2009-05-15 |
Family
ID=37492339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06803891T ATE428702T1 (de) | 2005-09-21 | 2006-09-20 | Verfahren zur herstellung von aminosäurederivaten |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1945621B1 (de) |
| JP (1) | JP2009508961A (de) |
| CN (1) | CN101268061B (de) |
| AT (1) | ATE428702T1 (de) |
| DE (1) | DE602006006334D1 (de) |
| WO (1) | WO2007038116A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111004145B (zh) * | 2019-12-11 | 2021-06-08 | 中山大学 | 一种手性光学酰胺取代的α,β-二氨基酸衍生物及其制备方法和应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2822827B1 (fr) * | 2001-03-28 | 2003-05-16 | Sanofi Synthelabo | Nouveaux derives de n-(arylsulfonyl) beta-aminoacides comportant un groupe aminomethyle substitue, leur procede de preparation et les compositions pharmaceutiques en contenant |
-
2006
- 2006-09-20 CN CN2006800345763A patent/CN101268061B/zh not_active Expired - Fee Related
- 2006-09-20 WO PCT/US2006/036607 patent/WO2007038116A1/en not_active Ceased
- 2006-09-20 JP JP2008532343A patent/JP2009508961A/ja not_active Withdrawn
- 2006-09-20 EP EP06803891A patent/EP1945621B1/de not_active Not-in-force
- 2006-09-20 DE DE602006006334T patent/DE602006006334D1/de active Active
- 2006-09-20 AT AT06803891T patent/ATE428702T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009508961A (ja) | 2009-03-05 |
| EP1945621A1 (de) | 2008-07-23 |
| CN101268061A (zh) | 2008-09-17 |
| CN101268061B (zh) | 2011-06-08 |
| DE602006006334D1 (de) | 2009-05-28 |
| EP1945621B1 (de) | 2009-04-15 |
| WO2007038116A1 (en) | 2007-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |