ATE430745T1 - Aza- und polyaza naphthalenyl karboxamide als inhibitoren der hiv-integrase - Google Patents

Aza- und polyaza naphthalenyl karboxamide als inhibitoren der hiv-integrase

Info

Publication number
ATE430745T1
ATE430745T1 AT01979582T AT01979582T ATE430745T1 AT E430745 T1 ATE430745 T1 AT E430745T1 AT 01979582 T AT01979582 T AT 01979582T AT 01979582 T AT01979582 T AT 01979582T AT E430745 T1 ATE430745 T1 AT E430745T1
Authority
AT
Austria
Prior art keywords
polyaza
aza
inhibitors
hiv integrase
naphthalenyl
Prior art date
Application number
AT01979582T
Other languages
English (en)
Inventor
Neville Anthony
Robert Gomez
Steven Young
Melissa Egbertson
John Wai
Linghang Zhuang
Mark Embrey
Lekhanh Tran
Jeffrey Melamed
H Langford
James Guare
Thorsten FISHER
Samson JOLLY
Michelle KUO
Debra Perlow
Jennifer Bennett
Timothy FUNK
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE430745T1 publication Critical patent/ATE430745T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT01979582T 2000-10-12 2001-10-09 Aza- und polyaza naphthalenyl karboxamide als inhibitoren der hiv-integrase ATE430745T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23970700P 2000-10-12 2000-10-12
US28165601P 2001-04-05 2001-04-05
PCT/US2001/031456 WO2002030930A2 (en) 2000-10-12 2001-10-09 Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors

Publications (1)

Publication Number Publication Date
ATE430745T1 true ATE430745T1 (de) 2009-05-15

Family

ID=26932782

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01979582T ATE430745T1 (de) 2000-10-12 2001-10-09 Aza- und polyaza naphthalenyl karboxamide als inhibitoren der hiv-integrase

Country Status (26)

Country Link
US (2) US6921759B2 (de)
EP (1) EP1326865B1 (de)
JP (1) JP4252797B2 (de)
KR (1) KR20030036922A (de)
CN (1) CN1469878A (de)
AR (1) AR033845A1 (de)
AT (1) ATE430745T1 (de)
AU (3) AU2002211874A1 (de)
BG (1) BG107677A (de)
BR (1) BR0114610A (de)
CA (1) CA2425440C (de)
CZ (1) CZ20031028A3 (de)
DE (1) DE60138635D1 (de)
EA (1) EA200300449A1 (de)
EE (1) EE200300145A (de)
HU (1) HUP0302367A2 (de)
IL (1) IL155089A0 (de)
IS (1) IS6760A (de)
MX (1) MXPA03003263A (de)
NO (1) NO20031672L (de)
NZ (1) NZ525088A (de)
PE (1) PE20020509A1 (de)
PL (1) PL360944A1 (de)
SK (1) SK4322003A3 (de)
WO (2) WO2002030931A2 (de)
YU (1) YU27903A (de)

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Also Published As

Publication number Publication date
PE20020509A1 (es) 2002-06-20
US20030055071A1 (en) 2003-03-20
NO20031672D0 (no) 2003-04-11
JP2004511483A (ja) 2004-04-15
BG107677A (bg) 2003-11-28
SK4322003A3 (en) 2003-09-11
WO2002030930A3 (en) 2002-08-29
WO2002030931A3 (en) 2002-10-24
AU2002211874A1 (en) 2002-04-22
EA200300449A1 (ru) 2003-10-30
KR20030036922A (ko) 2003-05-09
YU27903A (sh) 2006-05-25
AR033845A1 (es) 2004-01-07
AU2002211527B2 (en) 2006-08-24
DE60138635D1 (de) 2009-06-18
US20050176718A1 (en) 2005-08-11
PL360944A1 (en) 2004-09-20
EP1326865A2 (de) 2003-07-16
NZ525088A (en) 2004-11-26
CA2425440A1 (en) 2002-04-18
CZ20031028A3 (cs) 2003-08-13
MXPA03003263A (es) 2003-06-06
IL155089A0 (en) 2003-10-31
CA2425440C (en) 2010-04-13
WO2002030930A2 (en) 2002-04-18
AU1152702A (en) 2002-04-22
CN1469878A (zh) 2004-01-21
IS6760A (is) 2003-03-27
EE200300145A (et) 2003-06-16
US6921759B2 (en) 2005-07-26
HUP0302367A2 (hu) 2003-11-28
EP1326865B1 (de) 2009-05-06
JP4252797B2 (ja) 2009-04-08
WO2002030931A2 (en) 2002-04-18
BR0114610A (pt) 2005-12-13
NO20031672L (no) 2003-06-05

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