ATE431361T1 - Verwendung vom transportergen oatp-c zur screening von testsubstanzen - Google Patents

Verwendung vom transportergen oatp-c zur screening von testsubstanzen

Info

Publication number
ATE431361T1
ATE431361T1 AT04077191T AT04077191T ATE431361T1 AT E431361 T1 ATE431361 T1 AT E431361T1 AT 04077191 T AT04077191 T AT 04077191T AT 04077191 T AT04077191 T AT 04077191T AT E431361 T1 ATE431361 T1 AT E431361T1
Authority
AT
Austria
Prior art keywords
oatp
transporter genes
test substances
screening test
transporter
Prior art date
Application number
AT04077191T
Other languages
English (en)
Inventor
Jun-Ichi Nezu
Asuka Ose
Akira Tsuji
Original Assignee
Chugai Pharmaceutical Co Ltd
Akira Tsuji
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Akira Tsuji filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE431361T1 publication Critical patent/ATE431361T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
AT04077191T 1999-09-21 2000-09-20 Verwendung vom transportergen oatp-c zur screening von testsubstanzen ATE431361T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26783599 1999-09-21

Publications (1)

Publication Number Publication Date
ATE431361T1 true ATE431361T1 (de) 2009-05-15

Family

ID=17450292

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04077191T ATE431361T1 (de) 1999-09-21 2000-09-20 Verwendung vom transportergen oatp-c zur screening von testsubstanzen

Country Status (7)

Country Link
US (3) US7045316B2 (de)
EP (4) EP2316848A1 (de)
JP (2) JP4838961B2 (de)
AT (1) ATE431361T1 (de)
AU (1) AU7317400A (de)
DE (1) DE60042220D1 (de)
WO (1) WO2001021792A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2316848A1 (de) 1999-09-21 2011-05-04 Chugai Seiyaku Kabushiki Kaisha Transportgene OATP-B, C, D und E
WO2002095069A2 (en) * 2001-05-18 2002-11-28 Astrazeneca Ab Methods
US20040171010A1 (en) * 2001-05-24 2004-09-02 Rachael Moore Methods
US20080319795A1 (en) * 2002-11-21 2008-12-25 Cdex, Inc. System and methods for detection and identification of chemical substances
US7723019B2 (en) * 2003-05-20 2010-05-25 University Of Kentucky Research Foundation Organic cation transporter preferentially expressed in hematopoietic cells and leukemias and uses thereof
US20070148703A1 (en) * 2003-06-20 2007-06-28 Genomembrane, Inc. Method of screening remedy for breast cancer
CA2629786C (en) 2005-11-17 2017-07-18 Karolinska Institutet Innovations Ab Human bocavirus and methods of diagnosis and treatment
US7435771B2 (en) 2005-11-23 2008-10-14 Arch Chemicals, Inc. Stable antifouling paint composition containing metal salt of pyrithione and cuprous oxide
SG193022A1 (en) * 2011-03-10 2013-10-30 Eisai R&D Man Co Ltd Method for screening for compound capable of enhancing or inhibiting oatp1b1 transport activity, and method for determining expression level of oatp1b1
KR102211189B1 (ko) 2012-09-11 2021-02-03 코닝 인코포레이티드 약물 트랜스포터 단백질(들) 및/또는 약물대사 효소(들)를 인코딩하는 유전자(들)를 일시적으로 과발현하는 소모성 냉동보존 세포

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GB1592954A (en) * 1976-12-16 1981-07-15 Int Inst Of Differentiation Cell line
EP0239102A3 (de) 1986-03-28 1989-07-12 Tsuji, Kimiyoshi Verfahren zur Herstellung eines Human-Human-Hybridoms
AU8507191A (en) 1990-08-29 1992-03-30 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
WO1993002227A1 (en) 1991-07-15 1993-02-04 Eco-Tec Limited Process and apparatus for treating fluoride containing acid solutions
AU3328493A (en) 1991-12-17 1993-07-19 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
ES2301158T3 (es) 1992-07-24 2008-06-16 Amgen Fremont Inc. Produccion de anticuerpos xenogenicos.
AU6819494A (en) 1993-04-26 1994-11-21 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
JPH11506309A (ja) * 1995-03-01 1999-06-08 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド ヒトアミン輸送体
EP0822830B1 (de) 1995-04-27 2008-04-02 Amgen Fremont Inc. Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8
WO1996034096A1 (en) 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
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JP2001519179A (ja) * 1997-10-09 2001-10-23 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ５３個のヒト分泌タンパク質
EP1093516A2 (de) * 1998-07-06 2001-04-25 Schering Corporation Säugergenen; dendritische zellen prostaglandin- förmigen transporterprotein (dc-pgt), hdtea84, hsljd37r und rankl, hcc5 chemokine, deubiquitine 11 und 12 (dub11, dub12), md-1, md2 und cyclin e2, zugehörige reagenzien und verfahren
EP1141282A2 (de) * 1998-08-07 2001-10-10 Axys Pharmaceuticals, Inc. Humäne anionstransporter-genen atnov
WO2000009557A1 (fr) * 1998-08-12 2000-02-24 Kazusa Dna Research Institute Foundation Nouveau gene et nouvelle proteine pgth codee par ce gene
JP2000116384A (ja) * 1998-08-12 2000-04-25 Kazusa Dna Kenkyusho 新規遺伝子及びそれにコ―ドされる蛋白質ｐｇｔｈ
WO2000026245A2 (en) * 1998-11-04 2000-05-11 Incyte Pharmaceuticals, Inc. Human membrane transport proteins
EP1131425A2 (de) * 1998-11-18 2001-09-12 Incyte Pharmaceuticals, Inc. Gene, die mit entzündungen verbunden sind
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EP1177287A2 (de) * 1999-04-09 2002-02-06 Chiron Corporation Sekretierte menschliche proteine
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DE60044433D1 (de) * 1999-05-20 2010-07-01 Bristol Myers Squibb Co Transportproteine fuer organische anionen
JP2001046083A (ja) * 1999-06-03 2001-02-20 Sankyo Co Ltd 肝臓に発現している新規トランスポーター遺伝子
WO2001009185A2 (en) * 1999-07-30 2001-02-08 Millennium Pharmaceuticals, Inc. Transmembrane transport proteins, nucleic acids encoding them and uses therefor
EP2316848A1 (de) 1999-09-21 2011-05-04 Chugai Seiyaku Kabushiki Kaisha Transportgene OATP-B, C, D und E
WO2001074897A2 (en) * 2000-04-03 2001-10-11 Curagen Corporation Protein amf-1 to amf-10 and nucleic acids encoding the same
US20020090622A1 (en) * 2000-08-23 2002-07-11 Monisola Adeokun Chemical compounds
DE10043748B4 (de) 2000-09-05 2004-01-15 W. C. Heraeus Gmbh & Co. Kg Zylinderförmiges Sputtertarget, Verfahren zu seiner Herstellung und Verwendung

Also Published As

Publication number Publication date
US20060121523A1 (en) 2006-06-08
JP5395767B2 (ja) 2014-01-22
EP1223217A4 (de) 2003-06-25
US8748128B2 (en) 2014-06-10
JP4838961B2 (ja) 2011-12-14
EP2030985A1 (de) 2009-03-04
JP2011015694A (ja) 2011-01-27
EP1223217A1 (de) 2002-07-17
WO2001021792A1 (en) 2001-03-29
US7045316B2 (en) 2006-05-16
EP2316848A1 (de) 2011-05-04
EP1486510A1 (de) 2004-12-15
DE60042220D1 (de) 2009-06-25
AU7317400A (en) 2001-04-24
US20100196960A1 (en) 2010-08-05
EP1486510B1 (de) 2009-05-13
US20030022199A1 (en) 2003-01-30

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