ATE431361T1 - Verwendung vom transportergen oatp-c zur screening von testsubstanzen - Google Patents

Verwendung vom transportergen oatp-c zur screening von testsubstanzen

Info

Publication number
ATE431361T1
ATE431361T1 AT04077191T AT04077191T ATE431361T1 AT E431361 T1 ATE431361 T1 AT E431361T1 AT 04077191 T AT04077191 T AT 04077191T AT 04077191 T AT04077191 T AT 04077191T AT E431361 T1 ATE431361 T1 AT E431361T1
Authority
AT
Austria
Prior art keywords
oatp
transporter genes
test substances
screening test
transporter
Prior art date
Application number
AT04077191T
Other languages
English (en)
Inventor
Jun-Ichi Nezu
Asuka Ose
Akira Tsuji
Original Assignee
Chugai Pharmaceutical Co Ltd
Akira Tsuji
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Akira Tsuji filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE431361T1 publication Critical patent/ATE431361T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04077191T 1999-09-21 2000-09-20 Verwendung vom transportergen oatp-c zur screening von testsubstanzen ATE431361T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26783599 1999-09-21

Publications (1)

Publication Number Publication Date
ATE431361T1 true ATE431361T1 (de) 2009-05-15

Family

ID=17450292

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04077191T ATE431361T1 (de) 1999-09-21 2000-09-20 Verwendung vom transportergen oatp-c zur screening von testsubstanzen

Country Status (7)

Country Link
US (3) US7045316B2 (de)
EP (4) EP2030985A1 (de)
JP (2) JP4838961B2 (de)
AT (1) ATE431361T1 (de)
AU (1) AU7317400A (de)
DE (1) DE60042220D1 (de)
WO (1) WO2001021792A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021792A1 (en) * 1999-09-21 2001-03-29 Chugai Seiyaku Kabushiki Kaisha Transporter genes oatp-b, c, d and e
EP1395680A2 (de) * 2001-05-18 2004-03-10 AstraZeneca AB Methode zum nachweis eines polymorphismus im humanen oatpb gen
US20040171010A1 (en) * 2001-05-24 2004-09-02 Rachael Moore Methods
US20080319795A1 (en) * 2002-11-21 2008-12-25 Cdex, Inc. System and methods for detection and identification of chemical substances
US7723019B2 (en) * 2003-05-20 2010-05-25 University Of Kentucky Research Foundation Organic cation transporter preferentially expressed in hematopoietic cells and leukemias and uses thereof
JPWO2004113558A1 (ja) * 2003-06-20 2006-09-14 株式会社ジェノメンブレン 乳癌治療剤のスクリーニング方法
AU2006314843B2 (en) 2005-11-17 2011-06-30 Karolinska Institutet Innovations Ab Human bocavirus and methods of diagnosis and treatment
US7435771B2 (en) 2005-11-23 2008-10-14 Arch Chemicals, Inc. Stable antifouling paint composition containing metal salt of pyrithione and cuprous oxide
US8945865B2 (en) * 2011-03-10 2015-02-03 Eisai R&D Management Co., Ltd. Method for screening for compound capable of enhancing or inhibiting OATP1B1 transport activity, and method for determining expression level of OATP1B1
JP6417554B2 (ja) 2012-09-11 2018-11-07 コーニング インコーポレイテッド 薬物輸送タンパク質および／または薬物代謝酵素をコード化する遺伝子を一過的に過剰発現する摂取できる凍結保存細胞

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EP0239102A3 (de) 1986-03-28 1989-07-12 Tsuji, Kimiyoshi Verfahren zur Herstellung eines Human-Human-Hybridoms
ES2246502T3 (es) 1990-08-29 2006-02-16 Genpharm International, Inc. Animales no humanos transgenicos capaces de producir anticuerpos heterologos.
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JPH07503132A (ja) 1991-12-17 1995-04-06 ジェンファーム　インターナショナル，インコーポレイティド 異種抗体を産生することができるトランスジェニック非ヒト動物
ES2301158T3 (es) 1992-07-24 2008-06-16 Amgen Fremont Inc. Produccion de anticuerpos xenogenicos.
AU6819494A (en) 1993-04-26 1994-11-21 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
EP0815220A4 (de) * 1995-03-01 2000-10-11 Human Genome Sciences Inc Menschlicher amintransporter
CA2219361C (en) 1995-04-27 2012-02-28 Abgenix, Inc. Human antibodies derived from immunized xenomice
WO1996034096A1 (en) 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
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EP1093516A2 (de) * 1998-07-06 2001-04-25 Schering Corporation Säugergenen; dendritische zellen prostaglandin- förmigen transporterprotein (dc-pgt), hdtea84, hsljd37r und rankl, hcc5 chemokine, deubiquitine 11 und 12 (dub11, dub12), md-1, md2 und cyclin e2, zugehörige reagenzien und verfahren
WO2000008157A2 (en) * 1998-08-07 2000-02-17 Axys Pharmaceuticals, Inc. Human anion transporter genes atnov
JP2000116384A (ja) * 1998-08-12 2000-04-25 Kazusa Dna Kenkyusho 新規遺伝子及びそれにコ―ドされる蛋白質ｐｇｔｈ
AU5196699A (en) * 1998-08-12 2000-03-06 Kazusa Dna Research Institute Foundation Novel gene and protein pgth encoded thereby
CA2349818A1 (en) * 1998-11-04 2000-05-11 Incyte Pharmaceuticals, Inc. Membrane transport proteins
EP1131425A2 (de) * 1998-11-18 2001-09-12 Incyte Pharmaceuticals, Inc. Gene, die mit entzündungen verbunden sind
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US6692934B1 (en) * 1999-05-20 2004-02-17 Bristol-Myers Squibb Co. Organic anion transport proteins
BR0010552A (pt) * 1999-05-20 2002-02-13 Bristol Myers Squibb Co Proteìnas de transporte de anions orgânicos
JP2001046083A (ja) * 1999-06-03 2001-02-20 Sankyo Co Ltd 肝臓に発現している新規トランスポーター遺伝子
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WO2001021792A1 (en) 1999-09-21 2001-03-29 Chugai Seiyaku Kabushiki Kaisha Transporter genes oatp-b, c, d and e
WO2001074897A2 (en) * 2000-04-03 2001-10-11 Curagen Corporation Protein amf-1 to amf-10 and nucleic acids encoding the same
US20020090622A1 (en) * 2000-08-23 2002-07-11 Monisola Adeokun Chemical compounds
DE10043748B4 (de) 2000-09-05 2004-01-15 W. C. Heraeus Gmbh & Co. Kg Zylinderförmiges Sputtertarget, Verfahren zu seiner Herstellung und Verwendung

Also Published As

Publication number Publication date
US20030022199A1 (en) 2003-01-30
DE60042220D1 (de) 2009-06-25
EP2030985A1 (de) 2009-03-04
JP4838961B2 (ja) 2011-12-14
US20060121523A1 (en) 2006-06-08
US8748128B2 (en) 2014-06-10
US20100196960A1 (en) 2010-08-05
AU7317400A (en) 2001-04-24
EP2316848A1 (de) 2011-05-04
US7045316B2 (en) 2006-05-16
WO2001021792A1 (en) 2001-03-29
JP5395767B2 (ja) 2014-01-22
EP1223217A4 (de) 2003-06-25
EP1486510A1 (de) 2004-12-15
EP1223217A1 (de) 2002-07-17
EP1486510B1 (de) 2009-05-13
JP2011015694A (ja) 2011-01-27

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