ATE431361T1 - Verwendung vom transportergen oatp-c zur screening von testsubstanzen - Google Patents

Verwendung vom transportergen oatp-c zur screening von testsubstanzen

Info

Publication number
ATE431361T1
ATE431361T1 AT04077191T AT04077191T ATE431361T1 AT E431361 T1 ATE431361 T1 AT E431361T1 AT 04077191 T AT04077191 T AT 04077191T AT 04077191 T AT04077191 T AT 04077191T AT E431361 T1 ATE431361 T1 AT E431361T1
Authority
AT
Austria
Prior art keywords
oatp
transporter genes
test substances
screening test
transporter
Prior art date
Application number
AT04077191T
Other languages
English (en)
Inventor
Jun-Ichi Nezu
Asuka Ose
Akira Tsuji
Original Assignee
Chugai Pharmaceutical Co Ltd
Akira Tsuji
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Akira Tsuji filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE431361T1 publication Critical patent/ATE431361T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04077191T 1999-09-21 2000-09-20 Verwendung vom transportergen oatp-c zur screening von testsubstanzen ATE431361T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26783599 1999-09-21

Publications (1)

Publication Number Publication Date
ATE431361T1 true ATE431361T1 (de) 2009-05-15

Family

ID=17450292

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04077191T ATE431361T1 (de) 1999-09-21 2000-09-20 Verwendung vom transportergen oatp-c zur screening von testsubstanzen

Country Status (7)

Country Link
US (3) US7045316B2 (de)
EP (4) EP1223217A4 (de)
JP (2) JP4838961B2 (de)
AT (1) ATE431361T1 (de)
AU (1) AU7317400A (de)
DE (1) DE60042220D1 (de)
WO (1) WO2001021792A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1223217A4 (de) * 1999-09-21 2003-06-25 Chugai Pharmaceutical Co Ltd Transporter-gene oatp-b, c, d und e
WO2002095069A2 (en) * 2001-05-18 2002-11-28 Astrazeneca Ab Methods
US20040171010A1 (en) * 2001-05-24 2004-09-02 Rachael Moore Methods
US20080319795A1 (en) * 2002-11-21 2008-12-25 Cdex, Inc. System and methods for detection and identification of chemical substances
US7723019B2 (en) * 2003-05-20 2010-05-25 University Of Kentucky Research Foundation Organic cation transporter preferentially expressed in hematopoietic cells and leukemias and uses thereof
JPWO2004113558A1 (ja) * 2003-06-20 2006-09-14 株式会社ジェノメンブレン 乳癌治療剤のスクリーニング方法
WO2007057062A1 (en) 2005-11-17 2007-05-24 Karolinska Institutet Innovations Ab Human bocavirus and methods of diagnosis and treatment
US7435771B2 (en) 2005-11-23 2008-10-14 Arch Chemicals, Inc. Stable antifouling paint composition containing metal salt of pyrithione and cuprous oxide
JP5830085B2 (ja) * 2011-03-10 2015-12-09 エーザイ・アール・アンド・ディー・マネジメント株式会社 Ｏａｔｐ１ｂ１の輸送活性を促進又は阻害する化合物をスクリーニングするための方法、及びｏａｔｐ１ｂ１発現量を測定するための方法
EP4056686A1 (de) 2012-09-11 2022-09-14 Corning Incorporated Verbrauchbare kryokonservierte zellen mit vorübergehender überexpression von gen(en), die für wirkstofftransporterprotein(e) und/oder wirkstoffmetabolisierende enzym(e) codieren

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EP0239102A3 (de) 1986-03-28 1989-07-12 Tsuji, Kimiyoshi Verfahren zur Herstellung eines Human-Human-Hybridoms
WO1996033735A1 (en) 1995-04-27 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
ATE158021T1 (de) 1990-08-29 1997-09-15 Genpharm Int Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
WO1993012227A1 (en) 1991-12-17 1993-06-24 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
WO1993002227A1 (en) 1991-07-15 1993-02-04 Eco-Tec Limited Process and apparatus for treating fluoride containing acid solutions
ES2301158T3 (es) 1992-07-24 2008-06-16 Amgen Fremont Inc. Produccion de anticuerpos xenogenicos.
JPH08509612A (ja) 1993-04-26 1996-10-15 ジェンファーム インターナショナル インコーポレイテッド 異種抗体を産生することができるトランスジェニック非ヒト動物
AU2271995A (en) * 1995-03-01 1996-09-18 Human Genome Sciences, Inc. Human amine transporter
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WO2000001817A2 (en) * 1998-07-06 2000-01-13 Schering Corporation Mammalian genes; dendritic cell prostaglandin-like transponder (dc-pgt), hdtea84, hsljd37r and rankl, hcc5 chemokine, deubiquitinating 11 and 12 (dub11, dub12), md-1, md2 and cyclin e2, related reagents and methods
WO2000008157A2 (en) * 1998-08-07 2000-02-17 Axys Pharmaceuticals, Inc. Human anion transporter genes atnov
AU5196699A (en) * 1998-08-12 2000-03-06 Kazusa Dna Research Institute Foundation Novel gene and protein pgth encoded thereby
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CA2349818A1 (en) * 1998-11-04 2000-05-11 Incyte Pharmaceuticals, Inc. Membrane transport proteins
AU1344400A (en) * 1998-11-18 2000-06-05 Incyte Pharmaceuticals, Inc. Inflammation-associated genes
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EP1223217A4 (de) * 1999-09-21 2003-06-25 Chugai Pharmaceutical Co Ltd Transporter-gene oatp-b, c, d und e
WO2001074897A2 (en) * 2000-04-03 2001-10-11 Curagen Corporation Protein amf-1 to amf-10 and nucleic acids encoding the same
US20020090622A1 (en) * 2000-08-23 2002-07-11 Monisola Adeokun Chemical compounds
DE10043748B4 (de) 2000-09-05 2004-01-15 W. C. Heraeus Gmbh & Co. Kg Zylinderförmiges Sputtertarget, Verfahren zu seiner Herstellung und Verwendung

Also Published As

Publication number Publication date
US8748128B2 (en) 2014-06-10
DE60042220D1 (de) 2009-06-25
US20060121523A1 (en) 2006-06-08
EP1223217A1 (de) 2002-07-17
EP2316848A1 (de) 2011-05-04
EP1223217A4 (de) 2003-06-25
EP1486510A1 (de) 2004-12-15
JP4838961B2 (ja) 2011-12-14
US20030022199A1 (en) 2003-01-30
JP2011015694A (ja) 2011-01-27
EP1486510B1 (de) 2009-05-13
EP2030985A1 (de) 2009-03-04
US20100196960A1 (en) 2010-08-05
US7045316B2 (en) 2006-05-16
WO2001021792A1 (en) 2001-03-29
JP5395767B2 (ja) 2014-01-22
AU7317400A (en) 2001-04-24

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