ATE438607T1 - Neues herstellungsverfahren für ein 5-hydroxy-3- oxo-hexansäure-derivat - Google Patents

Neues herstellungsverfahren für ein 5-hydroxy-3- oxo-hexansäure-derivat

Info

Publication number: ATE438607T1
Authority: AT; Austria
Prior art keywords: oxo; hydroxy; acid derivative; production process; new production
Prior art date: 2003-01-16

Application number

AT03772907T

Other languages

English (en)

Inventor

Hyun-Ik Shin

Bo-Seung Choi

Original Assignee

Lg Life Sciences Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-16

Filing date

2003-11-17

Publication date

2009-08-15

2003-11-17 Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd

2009-08-15 Application granted granted Critical

2009-08-15 Publication of ATE438607T1 publication Critical patent/ATE438607T1/de

Links

ZQPJZYKENZNLOW-UHFFFAOYSA-N 5-hydroxy-3-oxohexanoic acid Chemical class CC(O)CC(=O)CC(O)=O ZQPJZYKENZNLOW-UHFFFAOYSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title abstract 2
XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical compound C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 abstract 1
XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Natural products C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 abstract 1
238000007024 Blaise reaction Methods 0.000 abstract 1
229940121710 HMGCoA reductase inhibitor Drugs 0.000 abstract 1
229960005370 atorvastatin Drugs 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
239000006227 byproduct Substances 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 abstract 1
239000000047 product Substances 0.000 abstract 1
229960000672 rosuvastatin Drugs 0.000 abstract 1
BPRHUIZQVSMCRT-VEUZHWNKSA-N rosuvastatin Chemical compound CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O BPRHUIZQVSMCRT-VEUZHWNKSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT03772907T 2003-01-16 2003-11-17 Neues herstellungsverfahren für ein 5-hydroxy-3- oxo-hexansäure-derivat ATE438607T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR20030002991		2003-01-16
PCT/KR2003/002470 WO2004063132A1 (en)	2003-01-16	2003-11-17	Novel process for preparing a 5-hydroxy-3-oxo-hexanoic acid derivative

Publications (1)

Publication Number	Publication Date
ATE438607T1 true ATE438607T1 (de)	2009-08-15

Family

ID=36081186

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03772907T ATE438607T1 (de)	2003-01-16	2003-11-17	Neues herstellungsverfahren für ein 5-hydroxy-3- oxo-hexansäure-derivat

Country Status (11)

Country	Link
US (1)	US7081546B2 (de)
EP (1)	EP1583730B1 (de)
JP (1)	JP4252037B2 (de)
KR (1)	KR100979496B1 (de)
CN (1)	CN100582073C (de)
AT (1)	ATE438607T1 (de)
AU (1)	AU2003279583A1 (de)
CA (1)	CA2512630C (de)
DE (1)	DE60328717D1 (de)
IL (1)	IL169191A (de)
WO (1)	WO2004063132A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100771708B1 (ko) *	2005-12-28	2007-10-30	엘지전자 주식회사	센서 네트워크에서의 센서 노드 배터리 충전 장치와 그방법
US7732546B2 (en) *	2007-10-03	2010-06-08	Bausch & Lomb Incorporated	Use of silylated sulfonate monomers to improve contact lens wettability
KR101076680B1 (ko) *	2007-11-01	2011-10-26	한미홀딩스 주식회사	(6ｒ)-3-헥실-4-히드록시-6-운데실-5,6-다이히드로피란-2-온의 제조방법 및 이에 사용되는 중간체
KR100980379B1 (ko) *	2008-04-02	2010-09-06	주식회사 파마코스텍	광학활성을 갖는 5-히드록시-3-옥소헵타노에이트 유도체의제조방법
CN117304028A (zh) *	2023-09-24	2023-12-29	重庆普佑生物医药有限公司	一种瑞舒伐他汀钙中间体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5278313A (en) *	1992-03-27	1994-01-11	E. R. Squibb & Sons, Inc.	Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors
CN1162422C (zh)	1998-08-05	2004-08-18	钟渊化学工业株式会社	制备光学活性的2－[6－(羟甲基)－1,3－二噁烷－4－基]乙酸衍生物的方法
DE19857302C2 (de)	1998-12-14	2000-10-26	Forschungszentrum Juelich Gmbh	Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren, deren Salze und Ester
WO2000075099A1 (en) *	1999-06-04	2000-12-14	Kaneka Corporation	Processes for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives

2003
- 2003-11-17 AT AT03772907T patent/ATE438607T1/de not_active IP Right Cessation
- 2003-11-17 DE DE60328717T patent/DE60328717D1/de not_active Expired - Fee Related
- 2003-11-17 AU AU2003279583A patent/AU2003279583A1/en not_active Abandoned
- 2003-11-17 CA CA002512630A patent/CA2512630C/en not_active Expired - Fee Related
- 2003-11-17 KR KR1020057010123A patent/KR100979496B1/ko not_active Expired - Fee Related
- 2003-11-17 CN CN200380108888A patent/CN100582073C/zh not_active Expired - Fee Related
- 2003-11-17 WO PCT/KR2003/002470 patent/WO2004063132A1/en not_active Ceased
- 2003-11-17 JP JP2004566329A patent/JP4252037B2/ja not_active Expired - Fee Related
- 2003-11-17 EP EP03772907A patent/EP1583730B1/de not_active Expired - Lifetime
- 2003-11-17 US US10/540,524 patent/US7081546B2/en not_active Expired - Fee Related
2005
- 2005-06-15 IL IL169191A patent/IL169191A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL169191A0 (en)	2009-02-11
KR20050088299A (ko)	2005-09-05
IL169191A (en)	2011-03-31
CA2512630A1 (en)	2004-07-29
EP1583730B1 (de)	2009-08-05
US20060079710A1 (en)	2006-04-13
CN100582073C (zh)	2010-01-20
DE60328717D1 (de)	2009-09-17
AU2003279583A1 (en)	2004-08-10
EP1583730A1 (de)	2005-10-12
CN1738789A (zh)	2006-02-22
CA2512630C (en)	2009-01-20
US7081546B2 (en)	2006-07-25
EP1583730A4 (de)	2006-08-09
JP4252037B2 (ja)	2009-04-08
KR100979496B1 (ko)	2010-09-02
JP2006513245A (ja)	2006-04-20
WO2004063132A1 (en)	2004-07-29

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Legal Events

Date	Code	Title	Description
2010-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties