ATE438647T1 - N-ä3- ä3-(dimethylamino)-1-oxo-2-propenylüphenylü-n-e hyl-acetamide hydrochlorid - Google Patents

N-ä3- ä3-(dimethylamino)-1-oxo-2-propenylüphenylü-n-e hyl-acetamide hydrochlorid

Info

Publication number
ATE438647T1
ATE438647T1 AT08008434T AT08008434T ATE438647T1 AT E438647 T1 ATE438647 T1 AT E438647T1 AT 08008434 T AT08008434 T AT 08008434T AT 08008434 T AT08008434 T AT 08008434T AT E438647 T1 ATE438647 T1 AT E438647T1
Authority
AT
Austria
Prior art keywords
dimethylamino
oxo
propenylüphenylü
hyl
acetamide hydrochloride
Prior art date
Application number
AT08008434T
Other languages
English (en)
Inventor
Laszlo Czibula
Laszlo Dobay
Katalin Szoeke
Papp Eva Wernke
Badgy Judit Nagyne
Gabor Tarkanyi
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Application granted granted Critical
Publication of ATE438647T1 publication Critical patent/ATE438647T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/42Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/43Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT08008434T 2004-02-02 2005-01-31 N-ä3- ä3-(dimethylamino)-1-oxo-2-propenylüphenylü-n-e hyl-acetamide hydrochlorid ATE438647T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0400325A HUP0400325A3 (en) 2004-02-02 2004-02-02 Pure n-[3-(-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-n-ethyl-acetamide, process for its preparation and intermediates

Publications (1)

Publication Number Publication Date
ATE438647T1 true ATE438647T1 (de) 2009-08-15

Family

ID=89981959

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05708499T ATE420882T1 (de) 2004-02-02 2005-01-31 Verfahren zur synthese von n-ä3-(3- cyanopyrazoloä1,5aüpyrimidin-7-yl)-phenylü-n- ethylacetamid
AT08008434T ATE438647T1 (de) 2004-02-02 2005-01-31 N-ä3- ä3-(dimethylamino)-1-oxo-2-propenylüphenylü-n-e hyl-acetamide hydrochlorid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT05708499T ATE420882T1 (de) 2004-02-02 2005-01-31 Verfahren zur synthese von n-ä3-(3- cyanopyrazoloä1,5aüpyrimidin-7-yl)-phenylü-n- ethylacetamid

Country Status (9)

Country Link
EP (2) EP1950213B1 (de)
JP (1) JP2007519700A (de)
AT (2) ATE420882T1 (de)
DE (2) DE602005012365D1 (de)
EA (1) EA010830B1 (de)
HU (1) HUP0400325A3 (de)
NO (1) NO20063917L (de)
RS (1) RS20060427A (de)
WO (1) WO2005073235A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005099712A2 (en) * 2004-04-19 2005-10-27 Sanmar Speciality Chemicals Limited Process for preparation of n-[3-(3-cyanopyrazolo [1,5-a]pyrimidin-7-yl)phenyl]-n-ethylacetamide
WO2006070244A2 (en) * 2004-11-22 2006-07-06 Bakulesh Mafatlal Khamar A process for the preparation of zaleplon

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626538A (en) 1983-06-23 1986-12-02 American Cyanamid Company [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
US5714607A (en) 1995-12-01 1998-02-03 American Cyanamid Company Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide
TR200402588T3 (tr) * 2001-06-12 2004-11-22 Biogal Gyogyszergyar Rt N-[3-(3-siyanopirazolo[1,5-A]pirimidin-7-il)fenil]-N- etilasetamidin(zaleplon) üretim işlemi
CA2453751A1 (en) * 2001-08-01 2003-02-13 Biogal Gyogyszergyar Rt. Purification and crystalline forms of zapelon
PL207322B1 (pl) * 2002-05-14 2010-11-30 Adamed Społka Z Ograniczoną Odpowiedzialnością Sposób wytwarzania zaleplonu

Also Published As

Publication number Publication date
EP1950213A3 (de) 2008-08-13
DE602005015902D1 (de) 2009-09-17
RS20060427A (sr) 2008-08-07
EP1950213A2 (de) 2008-07-30
EA200601417A1 (ru) 2006-12-29
JP2007519700A (ja) 2007-07-19
NO20063917L (no) 2006-11-01
HUP0400325A3 (en) 2005-11-28
HU0400325D0 (en) 2004-04-28
EP1711501A2 (de) 2006-10-18
WO2005073235A3 (en) 2005-10-06
HUP0400325A2 (hu) 2005-09-28
ATE420882T1 (de) 2009-01-15
EA010830B1 (ru) 2008-12-30
EP1950213B1 (de) 2009-08-05
DE602005012365D1 (de) 2009-03-05
WO2005073235A2 (en) 2005-08-11
EP1711501B1 (de) 2009-01-14

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Legal Events

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