ATE420882T1 - Verfahren zur synthese von n-ä3-(3- cyanopyrazoloä1,5aüpyrimidin-7-yl)-phenylü-n- ethylacetamid - Google Patents

Verfahren zur synthese von n-ä3-(3- cyanopyrazoloä1,5aüpyrimidin-7-yl)-phenylü-n- ethylacetamid

Info

Publication number: ATE420882T1
Authority: AT; Austria
Prior art keywords: ethylacetamide; phenylü; synthesis; propenyl; dimethylamino
Prior art date: 2004-02-02

Application number

AT05708499T

Other languages

English (en)

Inventor

Laszlo Czibula

Laszlo Dobay

Katalin Szoeke

Papp Eva Werkne

Bagdy Judit Nagyne

Gabor Tarkanyi

Original Assignee

Richter Gedeon Nyrt

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-02

Filing date

2005-01-31

Publication date

2009-01-15

2005-01-31 Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt

2009-01-15 Application granted granted Critical

2009-01-15 Publication of ATE420882T1 publication Critical patent/ATE420882T1/de

Links

238000000034 method Methods 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
FZSDJRKAWHMQFF-UHFFFAOYSA-N n-[3-[3-(dimethylamino)prop-2-enoyl]phenyl]-n-ethylacetamide;hydrochloride Chemical compound Cl.CCN(C(C)=O)C1=CC=CC(C(=O)C=CN(C)C)=C1 FZSDJRKAWHMQFF-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT05708499T 2004-02-02 2005-01-31 Verfahren zur synthese von n-ä3-(3- cyanopyrazoloä1,5aüpyrimidin-7-yl)-phenylü-n- ethylacetamid ATE420882T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU0400325A HUP0400325A3 (en)	2004-02-02	2004-02-02	Pure n-[3-(-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-n-ethyl-acetamide, process for its preparation and intermediates

Publications (1)

Publication Number	Publication Date
ATE420882T1 true ATE420882T1 (de)	2009-01-15

Family

ID=89981959

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT05708499T ATE420882T1 (de)	2004-02-02	2005-01-31	Verfahren zur synthese von n-ä3-(3- cyanopyrazoloä1,5aüpyrimidin-7-yl)-phenylü-n- ethylacetamid
AT08008434T ATE438647T1 (de)	2004-02-02	2005-01-31	N-ä3- ä3-(dimethylamino)-1-oxo-2-propenylüphenylü-n-e hyl-acetamide hydrochlorid

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT08008434T ATE438647T1 (de)	2004-02-02	2005-01-31	N-ä3- ä3-(dimethylamino)-1-oxo-2-propenylüphenylü-n-e hyl-acetamide hydrochlorid

Country Status (9)

Country	Link
EP (2)	EP1950213B1 (de)
JP (1)	JP2007519700A (de)
AT (2)	ATE420882T1 (de)
DE (2)	DE602005012365D1 (de)
EA (1)	EA010830B1 (de)
HU (1)	HUP0400325A3 (de)
NO (1)	NO20063917L (de)
RS (1)	RS20060427A (de)
WO (1)	WO2005073235A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005099712A2 (en) *	2004-04-19	2005-10-27	Sanmar Speciality Chemicals Limited	Process for preparation of n-[3-(3-cyanopyrazolo [1,5-a]pyrimidin-7-yl)phenyl]-n-ethylacetamide
WO2006070244A2 (en) *	2004-11-22	2006-07-06	Bakulesh Mafatlal Khamar	A process for the preparation of zaleplon

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4626538A (en)	1983-06-23	1986-12-02	American Cyanamid Company	[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
US5714607A (en)	1995-12-01	1998-02-03	American Cyanamid Company	Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide
TR200402588T3 (tr) *	2001-06-12	2004-11-22	Biogal Gyogyszergyar Rt	N-[3-(3-siyanopirazolo[1,5-A]pirimidin-7-il)fenil]-N- etilasetamidin(zaleplon) üretim işlemi
CA2453751A1 (en) *	2001-08-01	2003-02-13	Biogal Gyogyszergyar Rt.	Purification and crystalline forms of zapelon
PL207322B1 (pl) *	2002-05-14	2010-11-30	Adamed Społka Z Ograniczoną Odpowiedzialnością	Sposób wytwarzania zaleplonu

2004
- 2004-02-02 HU HU0400325A patent/HUP0400325A3/hu unknown
2005
- 2005-01-31 DE DE602005012365T patent/DE602005012365D1/de not_active Expired - Fee Related
- 2005-01-31 AT AT05708499T patent/ATE420882T1/de not_active IP Right Cessation
- 2005-01-31 AT AT08008434T patent/ATE438647T1/de not_active IP Right Cessation
- 2005-01-31 EA EA200601417A patent/EA010830B1/ru not_active IP Right Cessation
- 2005-01-31 EP EP08008434A patent/EP1950213B1/de not_active Expired - Lifetime
- 2005-01-31 JP JP2006550312A patent/JP2007519700A/ja active Pending
- 2005-01-31 RS RSP-2006/0427A patent/RS20060427A/sr unknown
- 2005-01-31 DE DE602005015902T patent/DE602005015902D1/de not_active Expired - Fee Related
- 2005-01-31 EP EP05708499A patent/EP1711501B1/de not_active Expired - Lifetime
- 2005-01-31 WO PCT/HU2005/000008 patent/WO2005073235A2/en not_active Ceased
2006
- 2006-09-01 NO NO20063917A patent/NO20063917L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1950213A3 (de)	2008-08-13
DE602005015902D1 (de)	2009-09-17
ATE438647T1 (de)	2009-08-15
RS20060427A (sr)	2008-08-07
EP1950213A2 (de)	2008-07-30
EA200601417A1 (ru)	2006-12-29
JP2007519700A (ja)	2007-07-19
NO20063917L (no)	2006-11-01
HUP0400325A3 (en)	2005-11-28
HU0400325D0 (en)	2004-04-28
EP1711501A2 (de)	2006-10-18
WO2005073235A3 (en)	2005-10-06
HUP0400325A2 (hu)	2005-09-28
EA010830B1 (ru)	2008-12-30
EP1950213B1 (de)	2009-08-05
DE602005012365D1 (de)	2009-03-05
WO2005073235A2 (en)	2005-08-11
EP1711501B1 (de)	2009-01-14

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Legal Events

Date	Code	Title	Description
2009-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties