ATE441102T1 - Verfahren zur detektion von intrazellulären parametern mit lumineszierenden proteinsonden zur selektion von molekülen, die diese parameter ändern kínnen - Google Patents

Verfahren zur detektion von intrazellulären parametern mit lumineszierenden proteinsonden zur selektion von molekülen, die diese parameter ändern kínnen

Info

Publication number
ATE441102T1
ATE441102T1 AT05718286T AT05718286T ATE441102T1 AT E441102 T1 ATE441102 T1 AT E441102T1 AT 05718286 T AT05718286 T AT 05718286T AT 05718286 T AT05718286 T AT 05718286T AT E441102 T1 ATE441102 T1 AT E441102T1
Authority
AT
Austria
Prior art keywords
parameters
change
luminescent protein
protein probe
detecting intracellular
Prior art date
Application number
AT05718286T
Other languages
English (en)
Inventor
Rosario Rizzuto
Tullio Pozzan
Paolo Pinton
Carlotta Giorgi
Original Assignee
Aequotech S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aequotech S R L filed Critical Aequotech S R L
Application granted granted Critical
Publication of ATE441102T1 publication Critical patent/ATE441102T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT05718286T 2004-03-26 2005-03-23 Verfahren zur detektion von intrazellulären parametern mit lumineszierenden proteinsonden zur selektion von molekülen, die diese parameter ändern kínnen ATE441102T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000598A ITMI20040598A1 (it) 2004-03-26 2004-03-26 Metodo per la rilevazione di parametri intracellulari con sonde proteiche luminescenti per lo screening di molecole in grado di alterare detti parametri
PCT/IB2005/000795 WO2005093429A2 (en) 2004-03-26 2005-03-23 Method for the detection of intracellular parameters with luminescent protein probes for the screening of molecules capable of altering said parameters

Publications (1)

Publication Number Publication Date
ATE441102T1 true ATE441102T1 (de) 2009-09-15

Family

ID=35033456

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05718286T ATE441102T1 (de) 2004-03-26 2005-03-23 Verfahren zur detektion von intrazellulären parametern mit lumineszierenden proteinsonden zur selektion von molekülen, die diese parameter ändern kínnen

Country Status (7)

Country Link
US (1) US20080003569A1 (de)
EP (1) EP1730499B1 (de)
JP (1) JP2007530027A (de)
AT (1) ATE441102T1 (de)
DE (1) DE602005016230D1 (de)
IT (1) ITMI20040598A1 (de)
WO (1) WO2005093429A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9238150B2 (en) 2005-07-22 2016-01-19 The Board Of Trustees Of The Leland Stanford Junior University Optical tissue interface method and apparatus for stimulating cells
US20090093403A1 (en) 2007-03-01 2009-04-09 Feng Zhang Systems, methods and compositions for optical stimulation of target cells
US10052497B2 (en) 2005-07-22 2018-08-21 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
US8926959B2 (en) 2005-07-22 2015-01-06 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
JP2009502140A (ja) 2005-07-22 2009-01-29 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 光活性化陽イオンチャネルおよびその使用
US9274099B2 (en) 2005-07-22 2016-03-01 The Board Of Trustees Of The Leland Stanford Junior University Screening test drugs to identify their effects on cell membrane voltage-gated ion channel
US8398692B2 (en) 2007-01-10 2013-03-19 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
US10434327B2 (en) 2007-10-31 2019-10-08 The Board Of Trustees Of The Leland Stanford Junior University Implantable optical stimulators
US10035027B2 (en) 2007-10-31 2018-07-31 The Board Of Trustees Of The Leland Stanford Junior University Device and method for ultrasonic neuromodulation via stereotactic frame based technique
ES2701349T3 (es) 2008-04-23 2019-02-21 Univ Leland Stanford Junior Sistemas, métodos y composiciones para la estimulación óptica de células diana
EP2294208B1 (de) * 2008-05-29 2013-05-08 The Board of Trustees of The Leland Stanford Junior University Zelllinie, system und verfahren zur optischen steuerung von sekundären botenstoffen
EP2303405A4 (de) 2008-06-17 2017-12-27 The Board of Trustees of the Leland Stanford Junior University Gerät und verfahren zur kontrolle der zellentwicklung
WO2010006049A1 (en) 2008-07-08 2010-01-14 The Board Of Trustees Of The Leland Stanford Junior University Materials and approaches for optical stimulation of the peripheral nervous system
NZ602416A (en) 2008-11-14 2014-08-29 Univ Leland Stanford Junior Optically-based stimulation of target cells and modifications thereto
US10568307B2 (en) 2010-11-05 2020-02-25 The Board Of Trustees Of The Leland Stanford Junior University Stabilized step function opsin proteins and methods of using the same
EP3486253A1 (de) 2010-11-05 2019-05-22 The Board of Trustees of The Leland Stanford Junior University Lichtaktivierte chimäre opsine und verwendungsverfahren dafür
CN106422081B (zh) 2010-11-05 2019-06-21 斯坦福大学托管董事会 用于光遗传学方法的光的上转换
US10086012B2 (en) 2010-11-05 2018-10-02 The Board Of Trustees Of The Leland Stanford Junior University Control and characterization of memory function
ES2625179T3 (es) 2010-11-05 2017-07-18 The Board Of Trustees Of The Leland Stanford Junior University Control optogenético de comportamientos relacionados con la recompensa
CN103384469B (zh) 2010-11-05 2016-06-15 斯坦福大学托管董事会 光控cns功能障碍
US8696722B2 (en) 2010-11-22 2014-04-15 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic magnetic resonance imaging
CA2859364C (en) 2011-12-16 2019-05-07 The Board Of Trustees Of The Leland Stanford Junior University Opsin polypeptides and methods of use thereof
ES2628006T3 (es) 2012-02-21 2017-08-01 Circuit Therapeutics, Inc. Composiciones para el tratamiento de trastornos neurogénicos del suelo pélvico
ES2742492T3 (es) 2013-03-15 2020-02-14 Univ Leland Stanford Junior Control optogenético del estado conductual
US10220092B2 (en) 2013-04-29 2019-03-05 The Board Of Trustees Of The Leland Stanford Junior University Devices, systems and methods for optogenetic modulation of action potentials in target cells
JP6621747B2 (ja) 2013-08-14 2019-12-18 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 疼痛を制御するための組成物及び方法
US10568516B2 (en) 2015-06-22 2020-02-25 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for imaging and/or optogenetic control of light-responsive neurons
US11294165B2 (en) 2017-03-30 2022-04-05 The Board Of Trustees Of The Leland Stanford Junior University Modular, electro-optical device for increasing the imaging field of view using time-sequential capture

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958713A (en) * 1995-01-31 1999-09-28 Novo Nordisk A/S Method of detecting biologically active substances by using green fluorescent protein
US6872538B1 (en) * 1998-07-06 2005-03-29 Euroscreen S.A. High-throughput screening diagnostic and/or dosage method of an agonist and/or an antagonist for a calcium-coupled receptor
WO2003082904A2 (en) * 2002-03-25 2003-10-09 Chemicon International Inc. Modified aequorins having enhanced glowing kinetics and methods of using same

Also Published As

Publication number Publication date
EP1730499B1 (de) 2009-08-26
US20080003569A1 (en) 2008-01-03
WO2005093429A2 (en) 2005-10-06
WO2005093429A3 (en) 2006-04-13
EP1730499A2 (de) 2006-12-13
JP2007530027A (ja) 2007-11-01
DE602005016230D1 (de) 2009-10-08
ITMI20040598A1 (it) 2004-06-26

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