ATE441102T1 - Verfahren zur detektion von intrazellulären parametern mit lumineszierenden proteinsonden zur selektion von molekülen, die diese parameter ändern kínnen - Google Patents

Verfahren zur detektion von intrazellulären parametern mit lumineszierenden proteinsonden zur selektion von molekülen, die diese parameter ändern kínnen

Info

Publication number
ATE441102T1
ATE441102T1 AT05718286T AT05718286T ATE441102T1 AT E441102 T1 ATE441102 T1 AT E441102T1 AT 05718286 T AT05718286 T AT 05718286T AT 05718286 T AT05718286 T AT 05718286T AT E441102 T1 ATE441102 T1 AT E441102T1
Authority
AT
Austria
Prior art keywords
parameters
change
luminescent protein
protein probe
detecting intracellular
Prior art date
Application number
AT05718286T
Other languages
English (en)
Inventor
Rosario Rizzuto
Tullio Pozzan
Paolo Pinton
Carlotta Giorgi
Original Assignee
Aequotech S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aequotech S R L filed Critical Aequotech S R L
Application granted granted Critical
Publication of ATE441102T1 publication Critical patent/ATE441102T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT05718286T 2004-03-26 2005-03-23 Verfahren zur detektion von intrazellulären parametern mit lumineszierenden proteinsonden zur selektion von molekülen, die diese parameter ändern kínnen ATE441102T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000598A ITMI20040598A1 (it) 2004-03-26 2004-03-26 Metodo per la rilevazione di parametri intracellulari con sonde proteiche luminescenti per lo screening di molecole in grado di alterare detti parametri
PCT/IB2005/000795 WO2005093429A2 (en) 2004-03-26 2005-03-23 Method for the detection of intracellular parameters with luminescent protein probes for the screening of molecules capable of altering said parameters

Publications (1)

Publication Number Publication Date
ATE441102T1 true ATE441102T1 (de) 2009-09-15

Family

ID=35033456

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05718286T ATE441102T1 (de) 2004-03-26 2005-03-23 Verfahren zur detektion von intrazellulären parametern mit lumineszierenden proteinsonden zur selektion von molekülen, die diese parameter ändern kínnen

Country Status (7)

Country Link
US (1) US20080003569A1 (de)
EP (1) EP1730499B1 (de)
JP (1) JP2007530027A (de)
AT (1) ATE441102T1 (de)
DE (1) DE602005016230D1 (de)
IT (1) ITMI20040598A1 (de)
WO (1) WO2005093429A2 (de)

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US9238150B2 (en) 2005-07-22 2016-01-19 The Board Of Trustees Of The Leland Stanford Junior University Optical tissue interface method and apparatus for stimulating cells
US9274099B2 (en) 2005-07-22 2016-03-01 The Board Of Trustees Of The Leland Stanford Junior University Screening test drugs to identify their effects on cell membrane voltage-gated ion channel
US8906360B2 (en) 2005-07-22 2014-12-09 The Board Of Trustees Of The Leland Stanford Junior University Light-activated cation channel and uses thereof
US8926959B2 (en) 2005-07-22 2015-01-06 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
US10052497B2 (en) 2005-07-22 2018-08-21 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
WO2008086470A1 (en) 2007-01-10 2008-07-17 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
WO2008106694A2 (en) 2007-03-01 2008-09-04 The Board Of Trustees Of The Leland Stanford Junior University Systems, methods and compositions for optical stimulation of target cells
US10035027B2 (en) 2007-10-31 2018-07-31 The Board Of Trustees Of The Leland Stanford Junior University Device and method for ultrasonic neuromodulation via stereotactic frame based technique
US10434327B2 (en) 2007-10-31 2019-10-08 The Board Of Trustees Of The Leland Stanford Junior University Implantable optical stimulators
MY169771A (en) 2008-04-23 2019-05-15 Univ Leland Stanford Junior Systems, methods and compositions for optical stimulation of target cells
AU2009256457B2 (en) * 2008-05-29 2014-06-26 The Board Of Trustees Of The Leland Stanford Junior University Cell line, system and method for optical control of secondary messengers
BRPI0915583A2 (pt) 2008-06-17 2016-01-26 Univ Leland Stanford Junior aparelho e métodos para controle do desenvolvimento celular
US9101759B2 (en) 2008-07-08 2015-08-11 The Board Of Trustees Of The Leland Stanford Junior University Materials and approaches for optical stimulation of the peripheral nervous system
NZ602416A (en) 2008-11-14 2014-08-29 Univ Leland Stanford Junior Optically-based stimulation of target cells and modifications thereto
EP2635341B1 (de) 2010-11-05 2018-08-08 The Board of Trustees of the Leland Stanford Junior University Aufwärtswandlung von licht zur verwendung in optogenetischen verfahren
WO2012061690A2 (en) 2010-11-05 2012-05-10 The Board Of Trustees Of The Leland Stanford Junior University Optically-controlled cns dysfunction
CN103491770B (zh) 2010-11-05 2016-06-08 斯坦福大学托管董事会 稳定阶跃函数视蛋白及其使用方法
CN106376525A (zh) 2010-11-05 2017-02-08 斯坦福大学托管董事会 记忆功能的控制和表征
CA2816971A1 (en) 2010-11-05 2012-05-10 The Board Of Trustees Of The Leland Stanford Junior University Light-activated chimeric opsins and methods of using the same
EP3225108A1 (de) 2010-11-05 2017-10-04 The Board of Trustees of The Leland Stanford Junior University Optogenetische steuerung eines verhaltens in zusammenhang mit belohnungen
US8696722B2 (en) 2010-11-22 2014-04-15 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic magnetic resonance imaging
EP3524676A1 (de) 2011-12-16 2019-08-14 The Board of Trustees of The Leland Stanford Junior University Opsin-polypeptide und verfahren zu ihrer verwendung
EP2817068B1 (de) 2012-02-21 2017-04-12 The Board of Trustees of the Leland Stanford Junior University Zusammensetzungen zur behandlung neurogener erkrankungen des beckenbodens
CA2906756A1 (en) 2013-03-15 2014-09-18 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic control of behavioral state
JP6549559B2 (ja) 2013-04-29 2019-07-24 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 標的細胞における活動電位の光遺伝学的調節のための装置、システム及び方法
CN105829538A (zh) 2013-08-14 2016-08-03 小利兰·斯坦福大学托管委员会 用于控制疼痛的组合物和方法
WO2016209654A1 (en) 2015-06-22 2016-12-29 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for imaging and/or optogenetic control of light-responsive neurons
US11294165B2 (en) 2017-03-30 2022-04-05 The Board Of Trustees Of The Leland Stanford Junior University Modular, electro-optical device for increasing the imaging field of view using time-sequential capture

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958713A (en) * 1995-01-31 1999-09-28 Novo Nordisk A/S Method of detecting biologically active substances by using green fluorescent protein
DE69905291T3 (de) * 1998-07-06 2009-06-25 Perkinelmer Cellular Sciences Belgium Sprl Bioluminenztest für agonisten oder antagonisten eines kalzium-gekuppelten-rezeptors
WO2003082904A2 (en) * 2002-03-25 2003-10-09 Chemicon International Inc. Modified aequorins having enhanced glowing kinetics and methods of using same

Also Published As

Publication number Publication date
WO2005093429A2 (en) 2005-10-06
DE602005016230D1 (de) 2009-10-08
US20080003569A1 (en) 2008-01-03
WO2005093429A3 (en) 2006-04-13
ITMI20040598A1 (it) 2004-06-26
EP1730499B1 (de) 2009-08-26
EP1730499A2 (de) 2006-12-13
JP2007530027A (ja) 2007-11-01

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