ATE443082T1 - Insulinvorstufen und verfahren zu deren herstellung - Google Patents
Insulinvorstufen und verfahren zu deren herstellungInfo
- Publication number
- ATE443082T1 ATE443082T1 AT02717999T AT02717999T ATE443082T1 AT E443082 T1 ATE443082 T1 AT E443082T1 AT 02717999 T AT02717999 T AT 02717999T AT 02717999 T AT02717999 T AT 02717999T AT E443082 T1 ATE443082 T1 AT E443082T1
- Authority
- AT
- Austria
- Prior art keywords
- insulin
- production
- precursors
- peptide
- insulin precursors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200100547 | 2001-04-02 | ||
| PCT/DK2002/000190 WO2002079250A1 (en) | 2001-04-02 | 2002-03-21 | Insulin precursors and a process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE443082T1 true ATE443082T1 (de) | 2009-10-15 |
Family
ID=8160415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02717999T ATE443082T1 (de) | 2001-04-02 | 2002-03-21 | Insulinvorstufen und verfahren zu deren herstellung |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1377608B1 (de) |
| JP (1) | JP4855640B2 (de) |
| AT (1) | ATE443082T1 (de) |
| DE (1) | DE60233722D1 (de) |
| ES (1) | ES2333942T3 (de) |
| WO (1) | WO2002079250A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004085472A1 (en) * | 2003-03-27 | 2004-10-07 | Novo Nordisk A/S | Method for making human insulin precursors and human insulin |
| EP1687428A1 (de) * | 2003-11-14 | 2006-08-09 | Novo Nordisk A/S | Verfahren zur herstellung von acyliertem insulin |
| JP5697831B2 (ja) * | 2003-12-03 | 2015-04-08 | ノヴォ ノルディスク アー/エス | 単鎖インシュリン |
| CN101243190B (zh) * | 2005-08-16 | 2015-05-13 | 诺沃-诺迪斯克有限公司 | 制备成熟胰岛素多肽的方法 |
| US8518668B2 (en) | 2006-09-27 | 2013-08-27 | Novo Nordisk A/S | Method for making maturated insulin polypeptides in a fungal cell |
| PL2229407T3 (pl) | 2008-01-09 | 2017-06-30 | Sanofi-Aventis Deutschland Gmbh | Nowe pochodne insuliny o ekstremalnie spowolnionym profilu czasu działania |
| NZ586589A (en) * | 2008-01-09 | 2012-04-27 | Sanofi Aventis Deutschland | Novel insulin analogues having an extremely delayed time-action profile |
| EP3228320B1 (de) | 2008-10-17 | 2019-12-18 | Sanofi-Aventis Deutschland GmbH | Kombination von einem insulin und einem glp-1-agonisten |
| EP3202394A1 (de) | 2009-07-06 | 2017-08-09 | Sanofi-Aventis Deutschland GmbH | Wässrige insulinzubereitungen enthaltend methionin |
| PT2554183T (pt) | 2009-11-13 | 2018-07-09 | Sanofi Aventis Deutschland | Composição farmacêutica que compreende um agonista de glp-1, uma insulina e metionina |
| PE20121316A1 (es) | 2009-11-13 | 2012-10-05 | Sanofi Aventis Deutschland | Composicion farmaceutica que comprende un agonista de glp-1 y metionina |
| US20140148384A1 (en) | 2010-08-30 | 2014-05-29 | Sanofi-Aventis Deutschland Gmbh | Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2 |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| CN108079281A (zh) | 2011-08-29 | 2018-05-29 | 赛诺菲-安万特德国有限公司 | 用于2型糖尿病患者中的血糖控制的药物组合 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| TWI641381B (zh) | 2013-02-04 | 2018-11-21 | 法商賽諾菲公司 | 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物 |
| JP2016521701A (ja) | 2013-06-07 | 2016-07-25 | ノヴォ ノルディスク アー/エス | 成熟インスリンポリペプチドを作製するための方法 |
| KR20160104724A (ko) | 2014-01-09 | 2016-09-05 | 사노피 | 인슐린 유사체 및/또는 인슐린 유도체의 안정화된 약제학적 제형 |
| RU2016132340A (ru) | 2014-01-09 | 2018-02-14 | Санофи | Стабилизированные фармацевтические составы на основе инсулина аспарта |
| CN105899191B (zh) | 2014-01-09 | 2020-06-16 | 赛诺菲 | 胰岛素类似物和/或胰岛素衍生物的稳定化不含甘油的药物制剂 |
| TWI758239B (zh) | 2014-12-12 | 2022-03-21 | 德商賽諾菲阿凡提斯德意志有限公司 | 甘精胰島素/利司那肽固定比率配製劑 |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK58285D0 (da) * | 1984-05-30 | 1985-02-08 | Novo Industri As | Peptider samt fremstilling og anvendelse deraf |
| DK336188D0 (da) * | 1988-06-20 | 1988-06-20 | Nordisk Gentofte | Propeptider |
| KR0150565B1 (ko) * | 1995-02-15 | 1998-08-17 | 김정재 | 유전자 조환에 의한 사람 인슐린 전구체의 제조 및 이를 이용한 인슐린의 제조방법 |
| US5840542A (en) * | 1995-07-28 | 1998-11-24 | Mogam Biotechnology Research Institute | Method for manufacture of proinsulin with high export yield |
| KR20030004315A (ko) * | 1999-12-29 | 2003-01-14 | 노보 노르디스크 에이/에스 | 효모에서 개선된 발효 수율을 갖는 인슐린 선구물질 및인슐린 선구물질 유사체의 제조 방법 |
| HUP0203475A3 (en) * | 1999-12-29 | 2005-11-28 | Novo Nordisk As | Method for making insulin precursors and insulin precursor analogs |
-
2002
- 2002-03-21 WO PCT/DK2002/000190 patent/WO2002079250A1/en not_active Ceased
- 2002-03-21 JP JP2002577874A patent/JP4855640B2/ja not_active Expired - Fee Related
- 2002-03-21 EP EP02717999A patent/EP1377608B1/de not_active Expired - Lifetime
- 2002-03-21 AT AT02717999T patent/ATE443082T1/de not_active IP Right Cessation
- 2002-03-21 ES ES02717999T patent/ES2333942T3/es not_active Expired - Lifetime
- 2002-03-21 DE DE60233722T patent/DE60233722D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2333942T3 (es) | 2010-03-03 |
| JP2004533821A (ja) | 2004-11-11 |
| WO2002079250A1 (en) | 2002-10-10 |
| DE60233722D1 (de) | 2009-10-29 |
| EP1377608B1 (de) | 2009-09-16 |
| JP4855640B2 (ja) | 2012-01-18 |
| EP1377608A1 (de) | 2004-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |