ATE443756T1 - Chondroitin synthasegen und verfahren zur dessen herstellung und anwendung - Google Patents
Chondroitin synthasegen und verfahren zur dessen herstellung und anwendungInfo
- Publication number
- ATE443756T1 ATE443756T1 AT01927344T AT01927344T ATE443756T1 AT E443756 T1 ATE443756 T1 AT E443756T1 AT 01927344 T AT01927344 T AT 01927344T AT 01927344 T AT01927344 T AT 01927344T AT E443756 T1 ATE443756 T1 AT E443756T1
- Authority
- AT
- Austria
- Prior art keywords
- synthase gene
- chondroitin
- production
- chondroitin synthase
- relates
- Prior art date
Links
- 108010009115 chondroitin synthase Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 abstract 1
- 229920001287 Chondroitin sulfate Polymers 0.000 abstract 1
- 229920000045 Dermatan sulfate Polymers 0.000 abstract 1
- 241000606856 Pasteurella multocida Species 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical class CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 abstract 1
- 229940059329 chondroitin sulfate Drugs 0.000 abstract 1
- AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 abstract 1
- 229940051593 dermatan sulfate Drugs 0.000 abstract 1
- 229940051027 pasteurella multocida Drugs 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19953800P | 2000-04-25 | 2000-04-25 | |
| PCT/US2001/013395 WO2001080810A2 (en) | 1999-11-10 | 2001-04-25 | Chondroitin synthase gene and methods of making and using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE443756T1 true ATE443756T1 (de) | 2009-10-15 |
Family
ID=22737955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01927344T ATE443756T1 (de) | 2000-04-25 | 2001-04-25 | Chondroitin synthasegen und verfahren zur dessen herstellung und anwendung |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1282684B1 (de) |
| JP (1) | JP2004512013A (de) |
| AT (1) | ATE443756T1 (de) |
| AU (2) | AU2001253805B2 (de) |
| CA (1) | CA2407415C (de) |
| DE (1) | DE60139993D1 (de) |
| WO (1) | WO2001080810A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030104601A1 (en) | 1999-04-01 | 2003-06-05 | Deangelis Paul L. | Chondroitin synthase gene and methods of making and using same |
| US7223571B2 (en) | 1998-04-02 | 2007-05-29 | The Board Of Regents Of The Universtiy Of Oklahoma | Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same |
| US20060188966A1 (en) | 1998-04-02 | 2006-08-24 | Deangelis Paul L | Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same |
| US7642071B2 (en) | 1999-04-01 | 2010-01-05 | The Board Of Regents Of The University Of Oklahoma | Methods of expressing gram-negative glycosaminoglycan synthase genes in gram-positive hosts |
| US8580290B2 (en) | 2001-05-08 | 2013-11-12 | The Board Of Regents Of The University Of Oklahoma | Heparosan-based biomaterials and coatings and methods of production and use thereof |
| EP1470235A4 (de) * | 2001-07-13 | 2008-05-21 | Univ Oklahoma | Glycosaminoglycanpolymere und verfahren zur deren herstellung und anwendung |
| JP4101548B2 (ja) | 2001-08-10 | 2008-06-18 | 生化学工業株式会社 | コンドロイチン合成酵素及びそれをコードするｄｎａ |
| ATE414774T1 (de) | 2002-05-31 | 2008-12-15 | Seikagaku Kogyo Co Ltd | Chondroitinsynthetase und das enzym codierende dna |
| US7232676B2 (en) * | 2002-05-31 | 2007-06-19 | Seikagaku Kogyo Kabushiki Kaisha | Chondroitin synthase and nucleic acid encoding the enzyme |
| CN104974973B (zh) * | 2007-04-24 | 2022-07-26 | 生化学工业株式会社 | 生产软骨素的细菌及生产软骨素的方法 |
| IT1394311B1 (it) * | 2009-05-25 | 2012-06-06 | Altergon Sa | Produzione biotecnologica di condroitina |
| JP5946703B2 (ja) * | 2011-06-30 | 2016-07-06 | 三洋化成工業株式会社 | 変性多糖の製造方法 |
| AU2013237894B2 (en) | 2012-03-30 | 2018-06-21 | The Board Of Regents Of The University Of Oklahoma | High molecular weight heparosan polymers and methods of production and use thereof |
| ITMI20120896A1 (it) | 2012-05-23 | 2013-11-24 | Bongulielmi Reto | Condroitina per uso in medicina |
| ITMI20121316A1 (it) | 2012-07-27 | 2014-01-28 | Altergon Sa | Complessi di condroitina ad assorbimento transcutaneo |
| CN104388372B (zh) * | 2014-12-04 | 2017-07-21 | 江南大学 | 一种产软骨素的重组枯草芽孢杆菌及其应用 |
| CN109628622A (zh) * | 2019-02-02 | 2019-04-16 | 广西壮族自治区兽医研究所 | 一种检测多杀性巴氏杆菌的实时定量lamp引物组及试剂盒 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4585754A (en) * | 1984-01-09 | 1986-04-29 | Valcor Scientific, Ltd. | Stabilization of proteins and peptides by chemical binding with chondroitin |
| EP1073460A4 (de) * | 1998-04-02 | 2001-05-23 | Univ Oklahoma | Nukleinsäure kodierend für hyaluronan synthase und methoden zur verwendung |
| CA2351593C (en) * | 1998-11-11 | 2012-02-21 | The Board Of Regents Of The University Of Oklahoma | Polymer grafting by polysaccharide synthases |
-
2001
- 2001-04-25 AT AT01927344T patent/ATE443756T1/de not_active IP Right Cessation
- 2001-04-25 DE DE60139993T patent/DE60139993D1/de not_active Expired - Lifetime
- 2001-04-25 EP EP01927344A patent/EP1282684B1/de not_active Expired - Lifetime
- 2001-04-25 JP JP2001577911A patent/JP2004512013A/ja active Pending
- 2001-04-25 CA CA2407415A patent/CA2407415C/en not_active Expired - Lifetime
- 2001-04-25 WO PCT/US2001/013395 patent/WO2001080810A2/en not_active Ceased
- 2001-04-25 AU AU2001253805A patent/AU2001253805B2/en not_active Ceased
- 2001-04-25 AU AU5380501A patent/AU5380501A/xx active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2407415A1 (en) | 2001-11-01 |
| JP2004512013A (ja) | 2004-04-22 |
| EP1282684A2 (de) | 2003-02-12 |
| WO2001080810A2 (en) | 2001-11-01 |
| EP1282684A4 (de) | 2004-05-12 |
| WO2001080810A3 (en) | 2002-05-16 |
| WO2001080810A9 (en) | 2002-03-07 |
| DE60139993D1 (de) | 2009-11-05 |
| AU5380501A (en) | 2001-11-07 |
| AU2001253805B2 (en) | 2006-08-03 |
| EP1282684B1 (de) | 2009-09-23 |
| CA2407415C (en) | 2011-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |